Hotels in Southeast Missouri

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Tonight
Jul 14 - Jul 15
Tomorrow
Jul 15 - Jul 16
This weekend
Jul 18 - Jul 20
Next weekend
Jul 25 - Jul 27

Where to stay in Southeast Missouri?

Pear Tree Inn Sikeston
Lobby

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1005)
The price is $94
$109 total
includes taxes & fees
Jul 19 - Jul 20
Pear Tree Inn Sikeston
Drury Inn & Suites Hayti Caruthersville
Lobby

Drury Inn & Suites Hayti Caruthersville

3.0 star property
9.4 out of 10, Exceptional, (1004)
The price is $94
$107 total
includes taxes & fees
Jul 19 - Jul 20
Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Jackson MO
Lobby

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1009)
The price is $90
$95 total
includes taxes & fees
Jul 20 - Jul 21
Drury Inn & Suites Jackson MO
Drury Inn & Suites Poplar Bluff
Lobby

Drury Inn & Suites Poplar Bluff

3.0 star property
9.2 out of 10, Wonderful, (884)
The price is $94
$106 total
includes taxes & fees
Aug 10 - Aug 11
Drury Inn & Suites Poplar Bluff
Postcard Cabins St. Francois
Exterior

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (16)
The price is $89
$133 total
includes taxes & fees
Jul 15 - Jul 16
Postcard Cabins St. Francois
Pear Tree Inn Cape Girardeau West
Lobby

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1009)
The price is $73
$82 total
includes taxes & fees
Jul 29 - Jul 30
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Sikeston, MO
Property amenity

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1006)
The price is $102
$117 total
includes taxes & fees
Jul 20 - Jul 21
Drury Inn & Suites Sikeston, MO
Microtel Inn & Suites by Wyndham Sainte Genevieve
Room, 2 Queen Beds, Non Smoking | Premium bedding, individually furnished, desk, laptop workspace

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 star property
8.8 out of 10, Excellent, (579)
The price is $86
$97 total
includes taxes & fees
Jul 20 - Jul 21
Microtel Inn & Suites by Wyndham Sainte Genevieve
Hampton Inn Poplar Bluff
Terrace/patio

Hampton Inn Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (736)
The price is $97
$109 total
includes taxes & fees
Aug 10 - Aug 11
Hampton Inn Poplar Bluff
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1003)
The price is $91
$103 total
includes taxes & fees
Aug 1 - Aug 2
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express & Suites Perryville by IHG
Exterior

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (480)
The price is $95
$109 total
includes taxes & fees
Jul 20 - Jul 21
Holiday Inn Express & Suites Perryville by IHG
The Riverview
Grand Riverview Two Queen Room | 1 bedroom, premium bedding, pillowtop beds, in-room safe

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (338)
The price is $117
$132 total
includes taxes & fees
Jul 15 - Jul 16
The Riverview
Drury Inn & Suites Cape Girardeau
Business center

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (956)
The price is $90
$102 total
includes taxes & fees
Jul 25 - Jul 26
Drury Inn & Suites Cape Girardeau
Fairfield Inn & Suites by Marriott Poplar Bluff
Lobby

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (771)
The price is $99
$112 total
includes taxes & fees
Aug 3 - Aug 4
Fairfield Inn & Suites by Marriott Poplar Bluff
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Free buffet breakfast

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (653)
The price is $111
$127 total
includes taxes & fees
Jul 20 - Jul 21
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby lounge

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (114)
The price is $93
$105 total
includes taxes & fees
Jul 20 - Jul 21
Fairfield Inn & Suites by Marriott Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1009)
The price is $90
$102 total
includes taxes & fees
Jul 20 - Jul 21
Drury Plaza Hotel Cape Girardeau Conference Center
Shepherd Mountain Inn
Fridge, microwave, coffee/tea maker

Shepherd Mountain Inn

2.5 star property
9.2 out of 10, Wonderful, (282)
The price is $120
$131 total
includes taxes & fees
Jul 15 - Jul 16
Shepherd Mountain Inn
Tru By Hilton Cape Girardeau
Room, 2 Queen Beds

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (41)
The price is $101
$115 total
includes taxes & fees
Jul 20 - Jul 21
Tru By Hilton Cape Girardeau
The Wildwood Hotel
Ballroom

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1544)
The price is $88
$107 total
includes taxes & fees
Jul 27 - Jul 28
The Wildwood Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Southeast Missouri

Taum Sauk Mountain in located in the St.Francis mountain range of south/central Missouri. It's also the highest point in Missouri. My kids are standing at the spot where the actual marker sign in

Elephant Rocks State Park

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

See properties in Elephant Rocks State Park
Elephant Rocks State Park

Learn more about Southeast Missouri

Southeast Missouri is well-known for its wineries and riverfront while attractions include Sam A. Baker State Park and K Bridge Recreation Area. This family-friendly city has something for everyone including its university life, restaurants, and sights like Lake Wappapello State Park and Clearwater Lake.

See all hotels in Southeast Missouri

Check out reviews of Southeast Missouri hotels guests love

Quality Inn

Quality Inn

10/10 Excellent
"Shadefor pool"
Savanna 1-night trip
Posted 23 hours ago
Quality Inn

Frequently asked questions

Can I book a refundable accommodation in Southeast Missouri?
If you need the flexibility to change your travel plans to Southeast Missouri, most hotels provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Southeast Missouri if I want a vacation home instead of a traditional hotel?
If you want a good alternative to a hotel, look over our selection of 129 vacation homes. In addition, there are 46 apartments and 7 condos.
Why should I book my Southeast Missouri accommodation with Hotels.com?
There are plenty of reasons to book your Southeast Missouri travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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