Hotels in Sikeston

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Check prices for these dates

Tonight
Apr 18 - Apr 19
Tomorrow
Apr 19 - Apr 20
Next weekend
Apr 24 - Apr 26
In two weeks
May 1 - May 3

Where to stay in Sikeston?

Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (173 reviews)
Discover Cape Girardeau from this hotel with free WiFi, parking, and continental breakfast. Take a refreshing dip in the indoor pool after exploring nearby attractions like Fort D Historic Site and Cape Splash Family Aquatic Center.
The price is $88
$100 total
includes taxes & fees
Apr 26 - Apr 27
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,001 reviews)
This peaceful Jackson hotel features a relaxing hot tub and indoor swimming pool. Free breakfast, WiFi, and parking add value, while the helpful staff ensures a comfortable stay. Litz Park and Lazy L Safari Park are nearby attractions to explore.
The price is $84
$89 total
includes taxes & fees
Apr 30 - May 1
Drury Inn & Suites Jackson MO
Exterior
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (747 reviews)
The price is $89
$96 total
includes taxes & fees
Apr 26 - Apr 27
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,009 reviews)
Located minutes from Shawnee National Forest, this hotel offers a refreshing indoor pool and hot tub for unwinding after adventures. Enjoy complimentary breakfast, WiFi, and parking while being close to Cape Splash Family Aquatic Center.
The price is $100
$113 total
includes taxes & fees
May 3 - May 4
Drury Plaza Hotel Cape Girardeau Conference Center
Free daily full breakfast
Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,001 reviews)
Experience comfort at this Sikeston hotel, offering free breakfast and parking close to Central Park. The helpful staff welcomes guests to enjoy the indoor pool and fitness center. With easy access to Sikeston Depot Museum, you'll find everything needed for a convenient Missouri stay.
The price is $77
$88 total
includes taxes & fees
Apr 26 - Apr 27
Best Western Plus Sikeston I-55
Desk, laptop workspace, blackout drapes, free cribs/infant beds
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
This tranquil hotel provides easy access to Cape Splash Family Aquatic Center and Conservation Nature Center. Enjoy complimentary breakfast, WiFi, and parking, with helpful staff ensuring a relaxing atmosphere near local restaurants and shopping.
The price is $72
$81 total
includes taxes & fees
Apr 23 - Apr 24
Pear Tree Inn Cape Girardeau West
Snack bar
Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (120 reviews)
This Cape Girardeau hotel offers convenient access to Shawnee National Forest and local nature attractions. Start each morning with free breakfast before exploring nearby conservation areas, then return for a swim in the indoor pool or a workout at the fitness center.
The price is $98
$111 total
includes taxes & fees
Apr 27 - Apr 28
Tru By Hilton Cape Girardeau
Individually decorated, individually furnished, desk, blackout drapes
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (766 reviews)
This peaceful hotel offers a complimentary continental breakfast, free WiFi, and convenient parking. Located near I-55 Exit 67, guests consistently praise the helpful staff and clean rooms that provide a quiet retreat after exploring local attractions.
The price is $65
$75 total
includes taxes & fees
Apr 19 - Apr 20
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
Discover Cape Girardeau from this central hotel with easy access to restaurants and shopping. Enjoy the indoor pool and fitness center, then wake up to a free breakfast. Helpful staff ensure a smooth stay with convenient free WiFi and parking.
The price is $102
$115 total
includes taxes & fees
May 17 - May 18
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby
Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (729 reviews)
Escape to this welcoming hotel featuring an outdoor pool and free daily English breakfast. Just minutes from Mississippi River and popular attractions, with free WiFi and parking. Guests rave about the helpful staff ready to make your stay enjoyable.
The price is $67
$75 total
includes taxes & fees
Apr 26 - Apr 27
Quality Inn Cape Girardeau North
Property amenity
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (72 reviews)
Located in Sikeston, this hotel offers free breakfast, WiFi, and parking. Take a refreshing swim in the indoor pool or grab a bite at the restaurant. Nearby attractions include Central Park and Sikeston Depot Museum for local exploration.
The price is $110
$125 total
includes taxes & fees
Apr 26 - Apr 27
Fairfield Inn & Suites by Marriott Sikeston
Indoor pool, outdoor pool
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,001 reviews)
Escape to this serene Sikeston hotel with both indoor and outdoor pools near restaurants and shopping. The fitness center, free breakfast, WiFi and parking enhance your stay, while the helpful staff ensures comfort just minutes from Central Park.
The price is $102
$117 total
includes taxes & fees
Apr 27 - Apr 28
Drury Inn & Suites Sikeston, MO
Lobby
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (804 reviews)
Wake up to a free breakfast at this Cape Girardeau hotel, just minutes from Shawnee National Forest and the Mississippi River. Swim in the indoor pool, work out in the fitness center, or relax on the terrace after exploring nearby aquatic attractions.
The price is $106
$119 total
includes taxes & fees
Apr 26 - Apr 27
Hampton Inn Cape Girardeau I 55 East
Free daily buffet breakfast
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,003 reviews)
Peaceful retreat in Cape Girardeau with shopping and restaurants within walking distance. Start your day with free breakfast before enjoying the indoor pool, then unwind in the hot tub. Near Cape Splash Family Aquatic Center with free WiFi and parking.
The price is $91
$103 total
includes taxes & fees
May 3 - May 4
Drury Inn & Suites Cape Girardeau
1 bedroom, desk, laptop workspace, blackout drapes
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,000 reviews)
Travelers rave about this serene retreat with helpful staff and clean rooms. Take advantage of free WiFi, parking, and on-the-go breakfast. Work out in the fitness center before exploring Central Park and Sikeston Depot Museum nearby.
The price is $68
$78 total
includes taxes & fees
Apr 26 - Apr 27
Days Inn and Suites by Wyndham Sikeston
Lobby
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very Good, (760 reviews)
Begin your day with a complimentary breakfast at this Jackson hotel near Mississippi River and Shawnee National Forest. The indoor pool offers year-round swimming while free WiFi and parking add value. Cape Girardeau Conservation Nature Center awaits nearby.
The price is $92
$100 total
includes taxes & fees
May 10 - May 11
Comfort Suites Jackson-Cape Girardeau
Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi
Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (629 reviews)
This Charleston motel offers complimentary WiFi, parking, and on-the-go breakfast daily. Located with convenient interstate access to Cape Girardeau, guests consistently praise the helpful staff. The comfortable accommodations provide a practical base for exploring southeastern Missouri.
The price is $65
$72 total
includes taxes & fees
Apr 21 - Apr 22
Super 8 by Wyndham Charleston/Sikeston East MO
Room, 1 King Bed, Non Smoking | View from room
Eagle Inn Charleston
Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
Active travelers will appreciate the health club at this comfortable Charleston motel. Free WiFi keeps you connected, while complimentary parking saves you money. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.
The price is $55
$61 total
includes taxes & fees
May 2 - May 3
Eagle Inn Charleston
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (459 reviews)
Experience Sikeston from this hotel with free breakfast, WiFi, and parking. Take a morning dip in the indoor pool or hit the fitness center. Near Central Park and Sikeston Depot Museum, guests love the helpful staff and clean rooms.
The price is $101
$114 total
includes taxes & fees
May 3 - May 4
Holiday Inn Express & Suites Sikeston Southwest by IHG
Lobby sitting area
The Riverview
The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (548 reviews)
Overlooking the Mississippi River, this hotel puts you near Isle Casino Cape Girardeau and Riverfront Park. Enjoy 2 restaurants including Beacon 53, plus free WiFi and complimentary parking during your business-friendly stay.
The price is $132
$149 total
includes taxes & fees
Apr 28 - Apr 29
The Riverview
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Showing deals for:Apr 18 - Apr 19
Indoor pool, outdoor pool
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,001 reviews)
The price is $160
per night
$184 total
includes taxes & fees
Drury Inn & Suites Sikeston, MO
Showing deals for:Apr 24 - Apr 26
Indoor pool, outdoor pool
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,001 reviews)
The price is $112
per night
$258 total
includes taxes & fees
Drury Inn & Suites Sikeston, MO

Check out family-friendly hotels in Sikeston

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1009)
The price is $100
$113 total
includes taxes & fees
May 3 - May 4
Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Sikeston?

Our prices for hotels in Sikeston are cheapest in December
Price trends for hotels in Sikeston
Pricing is based on two traveler single night rates
View properties in April
Currently viewing crowd sizes and weather for April.
Typical weather for Sikeston
April
High 20°C / low 10°C. Sunny most days.
View properties in April
20°
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April, no crowd data, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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25°
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May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
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30°
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June, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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32°
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July, no crowd data, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
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31°
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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28°
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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21°
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October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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14°
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November, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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9°
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December, no crowd data, average high temperature 9 degrees Celsius, average low temperature 2 degrees Celsius. Partly sunny.
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6°
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January, no crowd data, average high temperature 6 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
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8°
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February, no crowd data, average high temperature 8 degrees Celsius, average low temperature 0 degrees Celsius. Partly sunny.
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14°
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March, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
5°
Monthly weather averages (˚C)

Top landmarks in Sikeston

Sikeston Depot Museum

3.8/5 (57 reviews)
Step inside a restored 1916 train depot where local history meets art in downtown Sikeston. The free museum showcases the region's cotton-growing past and rotating exhibits by area artists.
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Central Park

3.6/5 (56 reviews)
This family-friendly oasis offers playground equipment and open spaces perfect for impromptu picnics. Pack a blanket and some snacks for a relaxed afternoon of people-watching and outdoor games.
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Sikeston and related destinations

Catch a hot roll in mid-air at Lambert's Cafe, where servers hurl fresh bread across the dining room with remarkable accuracy. The historic downtown reveals a slice of small-town Americana, while the Sikeston Depot Museum chronicles the railroad heritage that put this place on the map. Central Park offers a leafy respite after exploring Front Street Studio & Art Gallery's local artwork. The City of Miner Convention Center hosts events that draw visitors from across the region. Positioned at the crossroads of major highways, this makes an ideal stopover between larger destinations, though locals insist you'll find reasons to linger beyond the flying carbs that made the town famous.

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Good Day Sunshine Early Morning Sunshine passes through the fog and scatters through the leaves of a tree in Scott County Missouri

Check out reviews of Sikeston hotels guests love

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

8/10 Good
"With the exception of people's dogs barking all day and night, my stay at the motel was mostly rather pleasant. There are restaurants and retail establishments nearby, and the hotels location is conveniently close to the freeway. There were no problems with amenities or cleanliness, and the staff was welcoming."
Jeremy 2-night trip
Posted 21 hours ago
Super 8 by Wyndham Sikeston/Miner Area

Frequently asked questions

What accommodations do travelers recommend in Sikeston?
Guests like Drury Inn & Suites Sikeston, MO, Hampton Inn Sikeston and Best Western Plus Sikeston I-55.
Can I book a refundable accommodation in Sikeston?
If you're looking for the flexibility to change your travel plans to Sikeston, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Sikeston if I want a cheap accommodation?
Hampton Inn Sikeston, Best Western Plus Sikeston I-55 and Days Inn and Suites by Wyndham Sikeston are a few accommodations you might want to consider that'll save you money.
What will the weather in Sikeston be like during my vacation?
The warmest months in Sikeston are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.
Why should I book my Sikeston hotel with Hotels.com?
There are plenty of reasons to book your Sikeston travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.