Hotels in Cape Girardeau

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Check prices for these dates

Tonight
Oct 22 - Oct 23
Tomorrow
Oct 23 - Oct 24
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Where to stay in Cape Girardeau?

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Oct 26 - Oct 27
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A spacious living room with a sofa set, a coffee table, and a dining area.
A lobby with seating areas, a reception desk, and a bar.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

2. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
$118
$134 total
includes taxes & fees
Oct 30 - Oct 31
Courtyard by Marriott Cape Girardeau Downtown
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.
A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

3. The Riverview

The Riverview
Cape Girardeau
$114
$129 total
includes taxes & fees
Oct 25 - Oct 26
The Riverview
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
An outdoor patio with stone walls, wicker furniture, and large windows.
A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

4. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
$93
$105 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn Cape Girardeau I 55 East
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

5. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
$90
$102 total
includes taxes & fees
Nov 1 - Nov 2
Drury Inn & Suites Cape Girardeau
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

6. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
$95
$108 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

7. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$72
$81 total
includes taxes & fees
Oct 26 - Oct 27
Pear Tree Inn Cape Girardeau West
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

8. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
$101
$114 total
includes taxes & fees
Oct 29 - Oct 30
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

9. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
$71
$86 total
includes taxes & fees
Nov 22 - Nov 23
Candlewood Suites Cape Girardeau by IHG
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
A modern retail area with a display of local items and snacks.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

10. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
$89
$102 total
includes taxes & fees
Oct 29 - Oct 30
Tru By Hilton Cape Girardeau
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
$59
$67 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Cape Girardeau North
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.
A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

12. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
$70
$82 total
includes taxes & fees
Oct 25 - Oct 26
Town House Inn Cape Giradreau
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
A restaurant with a brick wall, a flat-screen TV, and a bar area.
A hotel room with two beds, a brick wall, and a wooden headboard.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

13. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
$80
$85 total
includes taxes & fees
Oct 28 - Oct 29
Drury Inn & Suites Jackson MO
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
A hotel room with two beds, a nightstand, a lamp, and a chair.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

14. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
$80
$86 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.
A room with large windows, two red upholstered chairs, a small table, and a potted plant.
A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.
A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

15. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
Jackson
$76
$82 total
includes taxes & fees
Nov 12 - Nov 13
Comfort Suites Jackson-Cape Girardeau
A living room with a blue wall, a fireplace, a sofa, and a chair.
A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.
A brick building with a sign reading "Mercantile & Hotel".
A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

16. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
$105
$114 total
includes taxes & fees
Oct 25 - Oct 26
EC Reed's Mercantile and Hotel
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.
A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.
A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.
Exterior

17. Town House Inn

Town House Inn
Jackson
$71
$77 total
includes taxes & fees
Oct 25 - Oct 26
Town House Inn
A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.
A stone building with a patio area, string lights, and outdoor seating.
A rustic building with a thatched roof, surrounded by dense greenery and a gravel path leading to it.
A cozy log cabin interior with a wooden staircase, a cushioned sofa, a small table, and a lamp.

18. Makanda Inn

Makanda Inn
Makanda
$262
$299 total
includes taxes & fees
Oct 26 - Oct 27
Makanda Inn
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A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$110
per night
$124 total
includes taxes & fees
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$90
per night
$102 total
includes taxes & fees
Pear Tree Inn Cape Girardeau West
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
$110
per night
$124 total
includes taxes & fees
Drury Inn & Suites Cape Girardeau
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
$124
per night
$141 total
includes taxes & fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.
A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

The Riverview

The Riverview
Cape Girardeau
$127
per night
$143 total
includes taxes & fees
Sign in for extra savings
The Riverview
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A spacious living room with a sofa set, a coffee table, and a dining area.
A lobby with seating areas, a reception desk, and a bar.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
$134
per night
$152 total
includes taxes & fees
Courtyard by Marriott Cape Girardeau Downtown
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
$73
per night
$83 total
includes taxes & fees
Quality Inn Cape Girardeau North
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
An outdoor patio with stone walls, wicker furniture, and large windows.
A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
$129
per night
$146 total
includes taxes & fees
Hampton Inn Cape Girardeau I 55 East
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
$94
per night
$112 total
includes taxes & fees
Candlewood Suites Cape Girardeau by IHG
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
$124
per night
$140 total
includes taxes & fees
Fairfield Inn & Suites by Marriott Cape Girardeau
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
A modern retail area with a display of local items and snacks.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
$109
per night
$124 total
includes taxes & fees
Tru By Hilton Cape Girardeau
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.
A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
$70
per night
$82 total
includes taxes & fees
Town House Inn Cape Giradreau

Check out pet-friendly hotels in Cape Girardeau

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Oct 26 - Oct 27
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
$90
$102 total
includes taxes & fees
Nov 1 - Nov 2
Drury Inn & Suites Cape Girardeau
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$72
$81 total
includes taxes & fees
Oct 26 - Oct 27
Pear Tree Inn Cape Girardeau West
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
An outdoor patio with stone walls, wicker furniture, and large windows.
A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
$93
$105 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn Cape Girardeau I 55 East
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
$71
$86 total
includes taxes & fees
Nov 22 - Nov 23
Candlewood Suites Cape Girardeau by IHG
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
A modern retail area with a display of local items and snacks.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
$89
$102 total
includes taxes & fees
Oct 29 - Oct 30
Tru By Hilton Cape Girardeau
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.
A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
$70
$82 total
includes taxes & fees
Oct 25 - Oct 26
Town House Inn Cape Giradreau
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You can also stay at hotels with a pool in Cape Girardeau

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
$95
$108 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Oct 26 - Oct 27
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
$90
$102 total
includes taxes & fees
Nov 1 - Nov 2
Drury Inn & Suites Cape Girardeau
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
$101
$114 total
includes taxes & fees
Oct 29 - Oct 30
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
An outdoor patio with stone walls, wicker furniture, and large windows.
A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
$93
$105 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn Cape Girardeau I 55 East
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
$71
$86 total
includes taxes & fees
Nov 22 - Nov 23
Candlewood Suites Cape Girardeau by IHG
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
A modern retail area with a display of local items and snacks.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
$89
$102 total
includes taxes & fees
Oct 29 - Oct 30
Tru By Hilton Cape Girardeau
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
$59
$67 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Cape Girardeau North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in Cape Girardeau are cheapest in December
Price trends for hotels in Cape Girardeau
Pricing is based on two traveler single night rates
View properties in October
Typical weather for Cape Girardeau
October
High 21°C / low 11°C. Sunny most days.
View properties in October
21°
11°
13°
4°
9°
1°
6°
-2°
8°
-1°
14°
5°
19°
9°
25°
15°
30°
20°
32°
21°
31°
20°
28°
17°
Monthly weather averages (˚C)

Top landmarks in Cape Girardeau

A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
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A cable-stayed bridge over a river with a rocky shoreline in the foreground.

Riverfront Bridge Park

8.8/10 (129 reviews)
Riverfront Bridge Park is worth a visit, located 0.7 mi (1.1 km) from central Cape Girardeau.
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Century Casino & Hotel Cape Girardeau

8.4/10 (176 reviews)
Century Casino & Hotel Cape Girardeau is 0.5 mi (0.8 km) from central Cape Girardeau, why not stop by during your stay.
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Riverfront Park

8.0/10 (2 reviews)
Riverfront Park is worth a visit when in central Cape Girardeau.
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Hunter Valley Winery

7.4/10 (48 reviews)
Travelers might want a tour of Hunter Valley Winery, just one of the places to visit, and located 9.3 mi (14.9 km) from central Cape Girardeau.
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Show Me Center

8.6/10 (40 reviews)
You can catch an event at Show Me Center, located 1.1 mi (1.8 km) from central Cape Girardeau.
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Cape Splash Family Aquatic Center

8.6/10 (21 reviews)
Why not give yourself a treat with a trip to Cape Splash Family Aquatic Center, one of the family attractions located 3.1 mi (5.1 km) from central Cape Girardeau. If you have fun at Cape Splash Family Aquatic Center, you'll love Cape Girardeau Conservation Nature Center, located nearby.
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eDen Spa & Salon

7.8/10 (25 reviews)
If massages and hot tubs are your thing, you might want to pamper yourself at eDen Spa & Salon located 0.4 mi (0.6 km) from central Cape Girardeau.
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Learn more about Cape Girardeau

Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Center or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic downtown invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.

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A nighttime view of a bridge with its cables illuminated against a starry sky.

Check out reviews of Cape Girardeau hotels guests love

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"I did not realize this was a Drury property until we got there, but I love Drury. Clean rooms, and very nice amenities. The staff was so friendly. We enjoyed our stay very much!"
Christina 1-night trip
Posted less than an hour ago
Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent
"Nice clean room"
James 1-night trip
Posted 1 hour ago
Candlewood Suites Cape Girardeau by IHG
The Riverview

The Riverview

8/10 Good
"The room was very spacious and beautiful"
Ebony 1-night trip
Posted 11 hours ago
The Riverview
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

10/10 Excellent
"Stayed here overnight for a wedding. Room was clean and they allowed us to check in early with no fee. Location is ideal, being walking distance from a Cracker Barrel and a breakfast place. Stores like Target and Walmart are only about a 5 minute drive."
Brittany 1-night trip
Posted 3 days ago
Hampton Inn Cape Girardeau I 55 East
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

8/10 Good
"Room was clean, bed was comfortable, staff was friendly, parking was easy. It was an older hotel and could use some renovation but would definitely stay again."
Jaime 1-night trip
Posted 4 days ago
Town House Inn Cape Giradreau
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

10/10 Excellent
"A new property that is very clean and well trained staff"
sterling 1-night trip
Posted 4 days ago
Tru By Hilton Cape Girardeau
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent
"I was surprised how reasonable the cost was considering how clean & nice all of the finishers were."
John 1-night trip
Posted 6 days ago
Courtyard by Marriott Cape Girardeau Downtown
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"We have stayed here a number of times over 20 years. It’s always clean and well maintained. Breakfast is very good. Staff is always friendly and helpful."
John 3-night trip
Posted 9 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Frequently asked questions

What hotels do travelers recommend in Cape Girardeau?
Guests like Drury Plaza Hotel Cape Girardeau Conference Center, The Riverview and Pear Tree Inn Cape Girardeau West.
Can I book a refundable hotel in Cape Girardeau?
If you need the flexibility to change your travel plans to Cape Girardeau, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Cape Girardeau if I'm looking for an affordable accommodation?
Pear Tree Inn Cape Girardeau West, Candlewood Suites Cape Girardeau by IHG and Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG are a few accommodations you might want to consider that'll save you money.
Where can I stay in Cape Girardeau if I want a vacation rental instead of a hotel?
If you want a good alternative to a hotel, look over our selection of 30 vacation homes. In addition, you can choose from 20 apartments.
What will the weather in Cape Girardeau be like during my vacation?
July and August are typically the warmest months in Cape Girardeau when the average temp is 76°F. January and February are the coldest months when the average temperature is 40°F. April and March are the months with the most rain.
Why should I book my Cape Girardeau hotel through Hotels.com?
There are lots of reasons to book your Cape Girardeau trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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