Hotels in Sanctuary

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Where to stay in Sanctuary?

A spacious living room with a view of the ocean, featuring a sofa set, a coffee table, and a console table with decorative items.

A modern kitchen with a large island, built-in appliances, and a view of the outdoors.

A modern kitchen with built-in appliances, a large island, and a view of the sea.

1. South Seas

5.5 km from Sanctuary

Jarrett

$202

$341 total

includes taxes & fees

Nov 11 - Nov 12

A covered outdoor area with a table and chairs, a ceiling fan, and a view of a beach with palm trees and a boat.

A beach with a view of the ocean and a sunset.

A multi-story hotel with a central entrance, balconies, and palm trees.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, and a dining area with white chairs and a table.

2. Island Inn

West End, 9.6 km from Sanctuary

Andrew

$215

$240 total

includes taxes & fees

Nov 8 - Nov 9

A resort with multiple-story buildings, palm trees, and a well-maintained lawn.

A hotel room with a bed, a view of the beach, and a window with curtains.

A pool area with lounge chairs and a building with a red roof.

A beach with a variety of seashells and pebbles.

3. Sanibel Island Beach Resort

Mid Island, 13.1 km from Sanctuary

Cary

$179

$227 total

includes taxes & fees

Oct 25 - Oct 26

A resort with a central pool, multiple lounge areas, and a beach view.

A covered porch with a view of the sea, a white railing, and two Adirondack chairs.

A sandy pathway leading to a beach with palm trees and a clear sky.

A table set for dining with a view of the sunset over the ocean.

4. Tween Waters Island Resort & Spa

3.7 km from Sanctuary

Matt

$341

$415 total

includes taxes & fees

Nov 23 - Nov 24

A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.

A beachfront hotel with palm trees, a sandy walkway, and a pool.

A modern kitchen with grey cabinets, a stainless steel refrigerator, a microwave, and a sink. There is a painting of a flamingo on the wall.

A bedroom with a large bed, a desk, and a chair. There is a sliding barn door and a painting of a beach on the wall.

5. Off the Charts Inn & Out Island Resort

8.8 km from Sanctuary

Catherine

$179

$234 total

includes taxes & fees

Oct 26 - Oct 27

A balcony with a table and chairs, large windows, and a view of the sea.

A swimming pool with clear blue water, surrounded by lounge chairs and umbrellas, and a building with a tiled roof.

A spacious living area with a high ceiling, a ceiling fan, a pool table, and a view of the outdoors.

6. The Westin Cape Coral Resort At Marina Village

18.1 km from Sanctuary

jessica

$137

$197 total

includes taxes & fees

Nov 22 - Nov 23

A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

A swimming pool area with lounge chairs, a small building, and a basketball court surrounded by palm trees and greenery.

A modern hotel room with a large bed, two armchairs, a small side table with a lamp, and a large window with blinds.

A hotel room with two beds, a large mirror, and a view of the outdoors.

7. Residence Inn by Marriott Fort Myers Sanibel

19.3 km from Sanctuary

Benjamin

$94

$105 total

includes taxes & fees

Oct 25 - Oct 26

A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

A resort pool area with a large pool, lounge chairs, and umbrellas.

A spacious lobby with a staircase, large windows, and a chandelier.

A table set for two on a beach with a view of the sea and distant islands.

8. Marriott Sanibel Harbour Resort & Spa

15.6 km from Sanctuary

Matthew

$207

$266 total

includes taxes & fees

Nov 8 - Nov 9

A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

A spacious indoor dining area with high ceilings, large windows, and modern orange chairs and white tables.

A modern lobby with a white brick wall, a flat-screen TV, and colorful abstract paintings. There are several seating areas with different styles of chairs.

A hotel room with two beds, a desk, a chair, artwork on the walls, and a television.

9. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

19.9 km from Sanctuary

Carol

$76

$85 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

A coffee station with two coffee machines, a coffee press, and various coffee cups and containers.

A hotel reception area with a check-in counter, a self-service kiosk, and a small kitchenette.

A modern hotel lobby with a sofa, chairs, a TV, and a dining area.

10. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

23.9 km from Sanctuary

Shannon

$101

$113 total

includes taxes & fees

Oct 28 - Oct 29

A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

A grocery store with shelves stocked with snacks, beverages, and dairy products.

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and artwork on the walls.

A swimming pool with lounge chairs and palm trees, surrounded by a building with a red roof and multiple windows.

11. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

22.9 km from Sanctuary

Felicia

$86

$96 total

includes taxes & fees

Oct 29 - Oct 30

A pathway flanked by palm trees and wooden buildings with thatched roofs.

A clear blue pool with lounge chairs and umbrellas, surrounded by palm trees and a thatched-roof structure.

A hotel room with a bed, a television, a desk, a chair, and a ceiling fan.

A thatched-roof structure with outdoor seating, surrounded by palm trees and a wooden deck.

12. Kona Kai Motel

Mid Island, 12.2 km from Sanctuary

Paloma

$179

$206 total

includes taxes & fees

Oct 26 - Oct 27

A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.

A resort pool area with a clear view of the ocean, surrounded by palm trees and lounge chairs.

A well-maintained garden with a wooden deck, palm trees, and a building in the background.

A wooden pathway leading to a beach with a clear view of the ocean.

13. Casa Ybel Resort

Ybel, 11.6 km from Sanctuary

Juan

$265

$296 total

includes taxes & fees

Oct 25 - Oct 26

A boat-shaped deck chair with cushions, positioned on a wooden deck with a white fence.

A kitchen with white cabinets, a microwave, a sink, and a green refrigerator.

14. The Anchor Inn

Mid Island, 12.8 km from Sanctuary

Ricardo E

$158

$191 total

includes taxes & fees

Oct 26 - Oct 27

A covered patio with tiled flooring, wooden lounge chairs, and a small table.

A hotel room with a bed, a desk, a chair, a TV mounted on the wall, and a sliding glass door leading to a balcony.

A modern living room with a grey sofa, a small table, and a TV mounted on the wall.

15. White Orchid Apartments

20 km from Sanctuary

Laura

$65

$105 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor seating area with tables and chairs, surrounded by palm trees and a thatched-roof structure.

A lobby with a mural of dolphins, seating area, and a reception desk.

A restaurant with a high wooden ceiling, hanging flags, and a variety of flags and decorations.

A nighttime view of a bar with a pool in front.

16. Dolphin Key Resort

23.8 km from Sanctuary

Patrick

$94

$105 total

includes taxes & fees

Nov 22 - Nov 23

A sign for Sunshine Island Inn with a palm tree and beach scene.

A poolside area with lounge chairs and umbrellas, surrounded by palm trees and a white fence.

A hotel room with a bed, a TV, a desk with chairs, a kitchenette, and a sliding glass door to a pool area.

A living room with a sofa, chairs, a wooden table, a ceiling fan, and a kitchen area with a refrigerator and sink.

17. Sunshine Island Inn

East End, 14.3 km from Sanctuary

Benjamin

$199

$229 total

includes taxes & fees

Oct 25 - Oct 26

A hotel reception area with a wooden reception desk, a digital phone, and a self-service beverage dispenser.

A conference room with a large wooden table, multiple chairs, and pendant lighting.

18. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

30.1 km from Sanctuary

Margaret

$79

$88 total

includes taxes & fees

Oct 30 - Oct 31

A beachside area with colorful Adirondack chairs, a fire pit, and a view of the water.

A bedroom with a large bed, a TV mounted on the wall, two bedside tables with lamps, and a window with blinds.

A modern kitchen with white cabinets, granite countertops, a built-in oven, and a microwave.

A living room with two sofas, a coffee table, a ceiling fan, a TV, and a cabinet.

19. Matlacha on Shoreview

20.2 km from Sanctuary

Jacquelyn

$60

$134 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

A modern reception desk with a digital display, a cash register, and a customer service counter.

A modern indoor space with a large table, chairs, and a television.

A swimming pool with lounge chairs and palm trees.

20. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

23.1 km from Sanctuary

Phillip

$87

$97 total

includes taxes & fees

Oct 27 - Oct 28

View all properties

Compare popular hotels in Sanctuary

Property	Property class	Guest rating
Island Inn	9.4 Exceptional 1,164 reviews	View
Sanibel Island Beach Resort	9.2 Wonderful 2,382 reviews	View
Off the Charts Inn & Out Island Resort	9.6 Exceptional 164 reviews	View
The Anchor Inn	9.8 Exceptional 80 reviews	View
South Seas	8.4 Very good 1,001 reviews	View

Our prices for hotels in Sanibel are cheapest in October

Check out reviews of Sanctuary hotels guests love

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

10/10 Excellent

"Staff was excellent we were late arriving and staff upgraded the room at no charge. The breakfast was excellent for free amenities"

DiamondHead Beach Resort

10/10 Excellent

"Great"

Hilton Garden Inn Ft Myers

10/10 Excellent

"Staff was amazing and hotel was quiet clean and convenient"

Sanibel Island Beach Resort

10/10 Excellent

"Amazing helpful staff at checkin and checkout. Extremely clean room."

The Lighthouse Resort Inn & Suites

10/10 Excellent

"Had various stays there before, but this was the BEST room. Location was terrific for us, pool & bar right outside the door, but away from the main Tiki Bar (where all the noise is). Will definitely ask for that room again on our next visit."

The Westin Cape Coral Resort At Marina Village

10/10 Excellent

"Very clean and nice place!"

Sundial Beach Resort & Spa

8/10 Good

"Gotta get rid of the sand chiggers."

Candlewood Suites Fort Myers Sanibel Gateway by IHG

10/10 Excellent

"Excellent"

Find out more about Sanctuary

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Hotels in Sanctuary

Room 1

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Sanctuary?

1. South Seas

2. Island Inn

3. Sanibel Island Beach Resort

4. Tween Waters Island Resort & Spa

5. Off the Charts Inn & Out Island Resort

6. The Westin Cape Coral Resort At Marina Village

7. Residence Inn by Marriott Fort Myers Sanibel

8. Marriott Sanibel Harbour Resort & Spa

9. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

10. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

11. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

12. Kona Kai Motel

13. Casa Ybel Resort

14. The Anchor Inn

15. White Orchid Apartments

16. Dolphin Key Resort

17. Sunshine Island Inn

18. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

19. Matlacha on Shoreview

20. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Compare popular hotels in Sanctuary

Typical weather for Sanibel

Check out reviews of Sanctuary hotels guests love

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

DiamondHead Beach Resort

Hilton Garden Inn Ft Myers

Sanibel Island Beach Resort

The Lighthouse Resort Inn & Suites

The Westin Cape Coral Resort At Marina Village

Sundial Beach Resort & Spa

Candlewood Suites Fort Myers Sanibel Gateway by IHG

Keep exploring

Hotels in Sanctuary

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Sanctuary?

1. South Seas

2. Island Inn

3. Sanibel Island Beach Resort

4. Tween Waters Island Resort & Spa

5. Off the Charts Inn & Out Island Resort

6. The Westin Cape Coral Resort At Marina Village

7. Residence Inn by Marriott Fort Myers Sanibel

8. Marriott Sanibel Harbour Resort & Spa

9. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

10. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

11. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

12. Kona Kai Motel

13. Casa Ybel Resort

14. The Anchor Inn

15. White Orchid Apartments

16. Dolphin Key Resort

17. Sunshine Island Inn

18. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

19. Matlacha on Shoreview

20. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Compare popular hotels in Sanctuary

Price trends for hotels in Sanibel

Typical weather for Sanibel

Check out reviews of Sanctuary hotels guests love

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

DiamondHead Beach Resort

Hilton Garden Inn Ft Myers

Sanibel Island Beach Resort

The Lighthouse Resort Inn & Suites

The Westin Cape Coral Resort At Marina Village

Sundial Beach Resort & Spa

Candlewood Suites Fort Myers Sanibel Gateway by IHG

Keep exploring