Hotels in Sanctuary

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Where to stay in Sanctuary?

A spacious living room with a large flat-screen TV, a ceiling fan, and a view of the ocean through large windows.

A spacious dining area with multiple tables and chairs, large windows offering ocean views, and hanging pendant lights.

A modern kitchen with a large island, a dining area with white wicker chairs, and a view of the ocean through large windows.

A spacious living room with a large window overlooking a beach, wooden flooring, and a ceiling fan.

1. South Seas

5.5 km from Sanctuary

Jarrett

$202

$341 total

includes taxes & fees

Nov 11 - Nov 12

A covered outdoor area with a table and chairs, a ceiling fan, and a view of a beach with palm trees and a boat.

A multi-story hotel with a central entrance, balconies, and palm trees.

A beach with a view of the ocean and a sunset.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, and a dining area with white chairs and a table.

2. Island Inn

West End, 9.6 km from Sanctuary

Andrew

$215

$240 total

includes taxes & fees

Nov 8 - Nov 9

A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

A spacious indoor dining area with high ceilings, large windows, and modern orange chairs and white tables.

A reception area with a beach view mural, a staircase, and a reception desk.

A hotel room with two beds, a desk, a chair, artwork on the walls, and a television.

3. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

19.9 km from Sanctuary

Carol

$84

$94 total

includes taxes & fees

Oct 28 - Oct 29

A resort with multiple-story buildings, palm trees, and a well-maintained lawn.

A beach with a variety of seashells and pebbles.

A hotel room with a bed, a view of the beach, and a window with curtains.

A pool area with lounge chairs and a building with a red roof.

4. Sanibel Island Beach Resort

Mid Island, 13.1 km from Sanctuary

Cary

$179

$227 total

includes taxes & fees

Oct 27 - Oct 28

A balcony with a table and chairs, large windows, and a view of the sea.

A swimming pool with clear blue water, surrounded by lounge chairs and umbrellas, and a building with a tiled roof.

A spacious living area with a high ceiling, a ceiling fan, a pool table, and a view of the outdoors.

5. The Westin Cape Coral Resort At Marina Village

18.1 km from Sanctuary

Danny

$146

$208 total

includes taxes & fees

Nov 15 - Nov 16

A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.

A resort with a pool, thatched umbrellas, and palm trees.

A beachfront hotel with palm trees, a sandy walkway, and a pool.

A bedroom with a large bed, a desk, and a chair. There is a sliding barn door and a painting of a beach on the wall.

6. Off the Charts Inn & Out Island Resort

8.8 km from Sanctuary

Catherine

$179

$234 total

includes taxes & fees

Oct 27 - Oct 28

A resort with a central pool, multiple lounge areas, and a beach view.

A covered porch with a view of the sea, a white railing, and two Adirondack chairs.

A sandy pathway leading to a beach with palm trees and a clear sky.

A hotel room with a bed, a desk, a TV, a ceiling fan, and a view of the outdoors.

7. Tween Waters Island Resort & Spa

3.7 km from Sanctuary

Matt

$341

$415 total

includes taxes & fees

Nov 24 - Nov 25

A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

A swimming pool area with lounge chairs, a small building, and a basketball court surrounded by palm trees and greenery.

A modern hotel room with a large bed, two armchairs, a small side table with a lamp, and a large window with blinds.

A hotel lobby with a reception desk, seating area, and a large window.

8. Residence Inn by Marriott Fort Myers Sanibel

19.3 km from Sanctuary

Susan

$94

$105 total

includes taxes & fees

Oct 27 - Oct 28

A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

A table set for two on a beach with a view of the sea and distant islands.

A spacious living area with wicker furniture, a chandelier, and large windows offering a view of palm trees and a balcony.

A resort pool area with a large pool, lounge chairs, and umbrellas.

9. Marriott Sanibel Harbour Resort & Spa

15.6 km from Sanctuary

Matthew

$207

$266 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

A modern indoor space with a large table, chairs, and a television.

A swimming pool with lounge chairs and palm trees.

A Holiday Inn Express & Suites building with a modern facade, multiple windows, and a covered entrance area.

10. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

23.1 km from Sanctuary

Phillip

$87

$97 total

includes taxes & fees

Oct 29 - Oct 30

A pathway flanked by palm trees and wooden buildings with thatched roofs.

A compact kitchen with a stainless steel refrigerator, a microwave, a coffee maker, and a sink.

A hotel room with a bed, a television, a desk, a chair, and a ceiling fan.

A thatched-roof structure with outdoor seating, surrounded by palm trees and a wooden deck.

11. Kona Kai Motel

Mid Island, 12.2 km from Sanctuary

Paloma

$179

$206 total

includes taxes & fees

Oct 27 - Oct 28

A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

A swimming pool with lounge chairs and palm trees, surrounded by a building with a red roof and multiple windows.

A reception desk with a wooden panel design, a welcome sign for 'Sunshine State', and a motivational rug on the floor.

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and artwork on the walls.

12. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

22.9 km from Sanctuary

Frank

$91

$101 total

includes taxes & fees

Oct 29 - Oct 30

A kitchen with white cabinets, a microwave, a sink, and a green refrigerator.

13. The Anchor Inn

Mid Island, 12.8 km from Sanctuary

Ricardo E

$158

$191 total

includes taxes & fees

Oct 27 - Oct 28

A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.

A well-maintained garden with a wooden deck, palm trees, and a building in the background.

A wooden pathway leading to a beach with a clear view of the ocean.

A large, two-story house with a wrap-around porch and a steeply pitched roof.

14. Casa Ybel Resort

Ybel, 11.6 km from Sanctuary

Juan

$265

$296 total

includes taxes & fees

Oct 27 - Oct 28

A swimming pool with a stone wall and palm trees, surrounded by a building with large windows and outdoor seating.

An outdoor patio area with round tables and chairs, ceiling fans, and a bar area with shelves of bottles.

A modern living room with a grey sofa, a wooden accent wall, a coffee table with a plant, and sheer curtains allowing natural light.

A modern reception area with a large abstract mural, a wooden reception desk, and a seating area with a long table and chairs.

15. Doubletree by Hilton Fort Myers at Bell Tower Shops

30.8 km from Sanctuary

Holly

$105

$118 total

includes taxes & fees

Oct 30 - Oct 31

A turquoise building with a red door, surrounded by potted plants and flowers.

A sign for Angler's Inn in Melita, Florida, with a contact number.

A patio area with outdoor seating, a grill, and a view of a building with large windows.

A bedroom with a bed, a nightstand, a painting, and a window with blinds.

16. Angler's Inn

18.8 km from Sanctuary

Cindy

$113

$215 total

includes taxes & fees

Nov 24 - Nov 25

An outdoor seating area with tables and chairs, surrounded by palm trees and a thatched-roof structure.

A nighttime view of a bar with a pool in front.

A lobby with a mural of dolphins, seating area, and a reception desk.

A bar with multiple liquor bottles and a large American flag in the background.

17. Dolphin Key Resort

23.8 km from Sanctuary

Patrick

$94

$105 total

includes taxes & fees

Nov 22 - Nov 23

A beachside area with colorful Adirondack chairs, a fire pit, and a view of the water.

A bedroom with a large bed, a TV mounted on the wall, two bedside tables with lamps, and a window with blinds.

A modern kitchen with white cabinets, granite countertops, a built-in oven, and a microwave.

A balcony with wicker furniture, a pool, and a white fence.

18. Matlacha on Shoreview

20.2 km from Sanctuary

Jacquelyn

$60

$134 total

includes taxes & fees

Oct 27 - Oct 28

A resort with multiple buildings featuring blue roofs, a beach, and a clear view of the ocean.

A pool area with lounge chairs and umbrellas, a wooden deck, and a view of the beach and ocean.

A hotel room with a large bed, a desk, a chair, and a view of the beach through the window.

A modern room with a large sliding glass door leading to a balcony with a view of the beach. There is a white sofa, a small table, and a white desk with a chair.

19. Shalimar Beach Resort

West End, 10.3 km from Sanctuary

Martha

$349

$389 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

A modern hotel lobby with a sofa, chairs, a TV, and a dining area.

A buffet with various food items, including omelets and other dishes, served in metal containers.

A Holiday Inn Express building with a clear entrance, palm trees, and a purple sky.

20. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

23.9 km from Sanctuary

Shannon

$101

$113 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Compare popular hotels in Sanctuary

Property	Property class	Guest rating
Island Inn	9.4 Exceptional 1,165 reviews	View
Sanibel Island Beach Resort	9.2 Wonderful 2,389 reviews	View
Off the Charts Inn & Out Island Resort	9.6 Exceptional 164 reviews	View
The Anchor Inn	10.0 Exceptional 81 reviews	View
South Seas	8.4 Very good 1,001 reviews	View

Our prices for hotels in Sanibel are cheapest in October

Check out reviews of Sanctuary hotels guests love

The Lighthouse Resort Inn & Suites

10/10 Excellent

"Clean, big rooms. Walking distance to the beach, stores, restaurants, bars, ice cream! Walmart is 6-7 minutes down the road which is helpful with kids."

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

10/10 Excellent

"Overall"

Sanibel Island Beach Resort

8/10 Good

"This is my second visit and I was never able to use the coffee machine in the room."

Tween Waters Island Resort & Spa

10/10 Excellent

"Tween waters was absolutely wonderful! No complaints. The room was beautiful, the amenities were clean, and the staff was So helpful"

The Bay Inn at Lani Kai

10/10 Excellent

"Right in the heart of everything, great spot to stay!"

Hilton Garden Inn Ft Myers

10/10 Excellent

"Staff was amazing and hotel was quiet clean and convenient"

Sundial Beach Resort & Spa

8/10 Good

"Gotta get rid of the sand chiggers."

Find out more about Sanctuary

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Hotels in Sanctuary

Room 1

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Sanctuary?

1. South Seas

2. Island Inn

3. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

4. Sanibel Island Beach Resort

5. The Westin Cape Coral Resort At Marina Village

6. Off the Charts Inn & Out Island Resort

7. Tween Waters Island Resort & Spa

8. Residence Inn by Marriott Fort Myers Sanibel

9. Marriott Sanibel Harbour Resort & Spa

10. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

11. Kona Kai Motel

12. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

13. The Anchor Inn

14. Casa Ybel Resort

15. Doubletree by Hilton Fort Myers at Bell Tower Shops

16. Angler's Inn

17. Dolphin Key Resort

18. Matlacha on Shoreview

19. Shalimar Beach Resort

20. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Compare popular hotels in Sanctuary

Typical weather for Sanibel

Check out reviews of Sanctuary hotels guests love

The Lighthouse Resort Inn & Suites

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Sanibel Island Beach Resort

Tween Waters Island Resort & Spa

The Bay Inn at Lani Kai

Hilton Garden Inn Ft Myers

Sundial Beach Resort & Spa

Keep exploring

Hotels in Sanctuary

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Sanctuary?

1. South Seas

2. Island Inn

3. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

4. Sanibel Island Beach Resort

5. The Westin Cape Coral Resort At Marina Village

6. Off the Charts Inn & Out Island Resort

7. Tween Waters Island Resort & Spa

8. Residence Inn by Marriott Fort Myers Sanibel

9. Marriott Sanibel Harbour Resort & Spa

10. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

11. Kona Kai Motel

12. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

13. The Anchor Inn

14. Casa Ybel Resort

15. Doubletree by Hilton Fort Myers at Bell Tower Shops

16. Angler's Inn

17. Dolphin Key Resort

18. Matlacha on Shoreview

19. Shalimar Beach Resort

20. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Compare popular hotels in Sanctuary

Price trends for hotels in Sanibel

Typical weather for Sanibel

Check out reviews of Sanctuary hotels guests love

The Lighthouse Resort Inn & Suites

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Sanibel Island Beach Resort

Tween Waters Island Resort & Spa

The Bay Inn at Lani Kai

Hilton Garden Inn Ft Myers

Sundial Beach Resort & Spa

Keep exploring