Hotels in Sanctuary

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Where to stay in Sanctuary?

A spacious kitchen with a large island, white cabinetry, and a view through the windows.

A bunk bed room with a ceiling fan, a patterned rug, and a dresser with drawers.

A modern living room with a sofa, a coffee table, and a TV. There is a balcony with a view of the ocean.

1. South Seas

5.5 km from Sanctuary

Jarrett

$202

$341 total

includes taxes & fees

Nov 11 - Nov 12

A resort with multiple-story buildings, palm trees, and a well-maintained lawn.

A hammock between palm trees with a view of the ocean.

A hotel room with a bed, a view of the beach, and a window with curtains.

A beach with a variety of seashells and pebbles.

2. Sanibel Island Beach Resort

Mid Island, 13.1 km from Sanctuary

Cary

$179

$227 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, a nightstand, a desk, a chair, a painting, and a bathroom with a mirror and sink.

A reception area with a beach view mural, a staircase, and a reception desk.

A modern lobby with a white brick wall, a flat-screen TV, and colorful abstract paintings. There are several seating areas with different styles of chairs.

A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

3. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

19.9 km from Sanctuary

Carol

$72

$80 total

includes taxes & fees

Oct 29 - Oct 30

A covered outdoor area with a table and chairs, a ceiling fan, and a view of a beach with palm trees and a boat.

A modern living room with a sofa, chairs, and a dining table. There is a kitchen area with cabinets and appliances.

A beach with a view of the ocean and a sunset.

A multi-story hotel with a central entrance, balconies, and palm trees.

4. Island Inn

West End, 9.6 km from Sanctuary

Andrew

$215

$240 total

includes taxes & fees

Nov 8 - Nov 9

A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.

A beachfront hotel with palm trees, a sandy walkway, and a pool.

A resort with a pool, thatched umbrellas, and palm trees.

A bedroom with a large bed, a desk, and a chair. There is a sliding barn door and a painting of a beach on the wall.

5. Off the Charts Inn & Out Island Resort

8.8 km from Sanctuary

Catherine

$179

$234 total

includes taxes & fees

Oct 26 - Oct 27

A balcony with a table and chairs, large windows, and a view of the sea.

A spacious living area with a high ceiling, a ceiling fan, a pool table, and a view of the outdoors.

An outdoor seating area with round tables and pink cushions, palm trees, and string lights against a twilight sky.

6. The Westin Cape Coral Resort At Marina Village

18.1 km from Sanctuary

jessica

$137

$197 total

includes taxes & fees

Nov 22 - Nov 23

A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

A table set for two on a beach with a view of the sea and distant islands.

A spacious living area with wicker furniture, a chandelier, and large windows offering a view of palm trees and a balcony.

A resort pool area with a large pool, lounge chairs, and umbrellas.

7. Marriott Sanibel Harbour Resort & Spa

15.6 km from Sanctuary

Matthew

$207

$266 total

includes taxes & fees

Nov 5 - Nov 6

A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

A hotel room with two beds, a large mirror, and a view of the outdoors.

A modern hotel room with a large bed, two armchairs, a small side table with a lamp, and a large window with blinds.

A swimming pool area with lounge chairs, a small building, and a basketball court surrounded by palm trees and greenery.

8. Residence Inn by Marriott Fort Myers Sanibel

19.3 km from Sanctuary

Benjamin

$94

$105 total

includes taxes & fees

Oct 25 - Oct 26

A resort with a central pool, multiple lounge areas, and a beach view.

A covered porch with a view of the sea, a white railing, and two Adirondack chairs.

A table set for dining with a view of the sunset over the ocean.

A sandy pathway leading to a beach with palm trees and a clear sky.

9. Tween Waters Island Resort & Spa

3.7 km from Sanctuary

Matt

$323

$395 total

includes taxes & fees

Nov 21 - Nov 22

A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

A reception desk with a wooden panel design, a welcome sign for 'Sunshine State', and a motivational rug on the floor.

A grocery store with shelves stocked with snacks, beverages, and dairy products.

A swimming pool with lounge chairs and palm trees, surrounded by a building with a red roof and multiple windows.

10. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

22.9 km from Sanctuary

Felicia

$78

$87 total

includes taxes & fees

Oct 29 - Oct 30

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

A modern hotel room with a wooden desk, a flat-screen TV, a chair, a wardrobe, and a framed picture on the wall.

A hotel reception area with a check-in counter, a self-service kiosk, and a small kitchenette.

A swimming pool with lounge chairs and palm trees.

11. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

23.9 km from Sanctuary

Shannon

$101

$113 total

includes taxes & fees

Oct 28 - Oct 29

A kitchen with white cabinets, a microwave, a sink, and a green refrigerator.

12. The Anchor Inn

Mid Island, 12.8 km from Sanctuary

Ricardo E

$148

$180 total

includes taxes & fees

Oct 28 - Oct 29

A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.

A resort pool area with a clear view of the ocean, surrounded by palm trees and lounge chairs.

A well-maintained garden with a wooden deck, palm trees, and a building in the background.

A wooden pathway leading to a beach with a clear view of the ocean.

13. Casa Ybel Resort

Ybel, 11.6 km from Sanctuary

Juan

$238

$265 total

includes taxes & fees

Oct 25 - Oct 26

A pathway flanked by palm trees and wooden buildings with thatched roofs.

A hotel room with a bed, a television, a desk, a chair, and a ceiling fan.

A compact kitchen with a stainless steel refrigerator, a microwave, a coffee maker, and a sink.

A clear blue pool with lounge chairs and umbrellas, surrounded by palm trees and a thatched-roof structure.

14. Kona Kai Motel

Mid Island, 12.2 km from Sanctuary

$179

$206 total

includes taxes & fees

Oct 26 - Oct 27

A hotel with a modern facade, palm trees, and a clear blue sky.

A gym with treadmills, elliptical machines, and exercise bikes.

A hotel room with a sofa, armchair, TV, and a small table with a vase.

A compact kitchen with a wooden table, chairs, a refrigerator, a microwave, and cabinets.

15. Candlewood Suites Fort Myers Sanibel Gateway by IHG

25.4 km from Sanctuary

Beatrice

$67

$75 total

includes taxes & fees

Oct 25 - Oct 26

A large, clear swimming pool with multiple lounge areas and palm trees.

A beach with rows of blue umbrellas and lounge chairs, a building with multiple balconies, and palm trees.

A beach-themed bar with wicker furniture, a bar counter with a variety of bottles, and a view of the beach through large windows.

A balcony with a view of the beach, wicker chairs, a table, and a railing.

16. Margaritaville Beach Resort Fort Myers

21.6 km from Sanctuary

Phyllis

$179

$250 total

includes taxes & fees

Oct 24 - Oct 25

An outdoor seating area with tables and chairs, surrounded by palm trees and a thatched-roof structure.

A nighttime view of a bar with a pool in front.

A bar with multiple liquor bottles and a large American flag in the background.

A lobby with a mural of dolphins, seating area, and a reception desk.

17. Dolphin Key Resort

23.8 km from Sanctuary

Patrick

$94

$105 total

includes taxes & fees

Nov 22 - Nov 23

A beachside area with colorful Adirondack chairs, a fire pit, and a view of the water.

A living room with two sofas, a coffee table, a ceiling fan, a TV, and a cabinet.

A bedroom with a large bed, a TV mounted on the wall, two bedside tables with lamps, and a window with blinds.

A balcony with wicker furniture, a pool, and a white fence.

18. Matlacha on Shoreview

20.2 km from Sanctuary

Jacquelyn

$60

$134 total

includes taxes & fees

Oct 25 - Oct 26

A sign for Sunshine Island Inn with a palm tree and beach scene.

A hotel room with a bed, a TV, a desk with chairs, a kitchenette, and a sliding glass door to a pool area.

A modern bathroom with a round mirror, a coffee maker, and a sink.

A living room with a sofa, chairs, a wooden table, a ceiling fan, and a kitchen area with a refrigerator and sink.

19. Sunshine Island Inn

East End, 14.3 km from Sanctuary

Benjamin

$199

$229 total

includes taxes & fees

Oct 23 - Oct 24

A modern hotel lobby with a seating area, a reception desk, and a dining area.

A modern hotel room with a flat-screen TV mounted on a wooden console, a microwave, a small sink, and a yellow chair.

A Hampton Inn & Suites hotel entrance with a 'Welcome' sign, palm trees, and a well-lit facade.

A hotel room with a bed, a desk, a chair, a TV, and a mirror.

20. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

22.6 km from Sanctuary

Amy

$97

$108 total

includes taxes & fees

Oct 29 - Oct 30

View all properties

Compare popular hotels in Sanctuary

Property	Property class	Guest rating
Tween Waters Island Resort & Spa	8.6 Excellent 1,000 reviews	View
Shalimar Beach Resort	9.8 Exceptional 108 reviews	View
South Seas	8.4 Very good 1,000 reviews	View
Sanibel Island Beach Resort	9.2 Wonderful 2,375 reviews	View
Island Inn	9.4 Exceptional 1,164 reviews	View

Our prices for hotels in Sanibel are cheapest in October

Check out reviews of Sanctuary hotels guests love

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

8/10 Good

"Nice staff and excellent breakfast. Hotel could use some sprucing up"

DiamondHead Beach Resort

10/10 Excellent

"Clean room, beach view, nice staff!"

Lani Kai Beachfront Resort

10/10 Excellent

"Beach"

The Lighthouse Resort Inn & Suites

10/10 Excellent

"Great staff, pools and tiki bars were awesome! Beach was across the street and restaurants were within a 10 minute walk."

Sanibel Island Beach Resort

10/10 Excellent

"Easy check in and check out. Steps from the beach. Very clean. Comfortable beds."

Pink Shell Beach Resort and Marina

10/10 Excellent

"Loved the time there, want to return again!"

Hilton Garden Inn Ft Myers

10/10 Excellent

"I stay often in Fort Myers (family), this is 1st at Garden Inn, I will definitely stay here in the future. Everything was immaculate, staff is friendly and ever so helpful. The rates were less than what I had been paying for someplace a few mins closer to the family. Discovered Garden Inn was <5 mins further, worth the extra few mins at less the cost. We ordered a breakfast to take to our room, cooked to order and plentiful."

The Westin Cape Coral Resort At Marina Village

10/10 Excellent

"Very clean and nice place!"

Sundial Beach Resort & Spa

8/10 Good

"Gotta get rid of the sand chiggers."

Find out more about Sanctuary

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Hotels in Sanctuary

Room 1

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Sanctuary?

1. South Seas

2. Sanibel Island Beach Resort

3. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

4. Island Inn

5. Off the Charts Inn & Out Island Resort

6. The Westin Cape Coral Resort At Marina Village

7. Marriott Sanibel Harbour Resort & Spa

8. Residence Inn by Marriott Fort Myers Sanibel

9. Tween Waters Island Resort & Spa

10. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

11. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

12. The Anchor Inn

13. Casa Ybel Resort

14. Kona Kai Motel

15. Candlewood Suites Fort Myers Sanibel Gateway by IHG

16. Margaritaville Beach Resort Fort Myers

17. Dolphin Key Resort

18. Matlacha on Shoreview

19. Sunshine Island Inn

20. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Compare popular hotels in Sanctuary

Typical weather for Sanibel

Check out reviews of Sanctuary hotels guests love

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

DiamondHead Beach Resort

Lani Kai Beachfront Resort

The Lighthouse Resort Inn & Suites

Sanibel Island Beach Resort

Pink Shell Beach Resort and Marina

Hilton Garden Inn Ft Myers

The Westin Cape Coral Resort At Marina Village

Sundial Beach Resort & Spa

Keep exploring

Hotels in Sanctuary

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Sanctuary?

1. South Seas

2. Sanibel Island Beach Resort

3. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

4. Island Inn

5. Off the Charts Inn & Out Island Resort

6. The Westin Cape Coral Resort At Marina Village

7. Marriott Sanibel Harbour Resort & Spa

8. Residence Inn by Marriott Fort Myers Sanibel

9. Tween Waters Island Resort & Spa

10. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

11. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

12. The Anchor Inn

13. Casa Ybel Resort

14. Kona Kai Motel

15. Candlewood Suites Fort Myers Sanibel Gateway by IHG

16. Margaritaville Beach Resort Fort Myers

17. Dolphin Key Resort

18. Matlacha on Shoreview

19. Sunshine Island Inn

20. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Compare popular hotels in Sanctuary

Price trends for hotels in Sanibel

Typical weather for Sanibel

Check out reviews of Sanctuary hotels guests love

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

DiamondHead Beach Resort

Lani Kai Beachfront Resort

The Lighthouse Resort Inn & Suites

Sanibel Island Beach Resort

Pink Shell Beach Resort and Marina

Hilton Garden Inn Ft Myers

The Westin Cape Coral Resort At Marina Village

Sundial Beach Resort & Spa

Keep exploring