Hotels in Sanctuary

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Sanctuary?

1. South Seas

South Seas
3.5 star property
5.5 km from Sanctuary
8.4 out of 10, Very good, (1,001 reviews)
"Rooms were very nice staff was very helpful great place to go with a family "
United States
Jarrett
The price is $206
$346 total
includes taxes & fees
Dec 1 - Dec 2
South Seas

2. Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
8.8 km from Sanctuary
9.6 out of 10, Exceptional, (165 reviews)
"The motel was clean and the staff was great! I’d go back there."
United States
Catherine
The price is $158
$210 total
includes taxes & fees
Dec 1 - Dec 2
Off the Charts Inn & Out Island Resort

3. Island Inn

Island Inn
3.5 star property
West End, 9.6 km from Sanctuary
9.4 out of 10, Exceptional, (1,168 reviews)
"Very clean room. Beautiful view of the ocean. Easy access to beach."
United States
Andrew
The price is $219
$244 total
includes taxes & fees
Nov 8 - Nov 9
Island Inn

4. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (2,415 reviews)
"Very nice place to stay right on the beach with nice pool as well."
United States
Cary
The price is $199
$250 total
includes taxes & fees
Nov 8 - Nov 9
Sanibel Island Beach Resort

5. Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
3.7 km from Sanctuary
8.6 out of 10, Excellent, (1,001 reviews)
"Great view, friendly staff!"
United States
Nicholas J
The price is $215
$275 total
includes taxes & fees
Nov 9 - Nov 10
Tween Waters Island Resort & Spa

6. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
19.9 km from Sanctuary
8.2 out of 10, Very good, (1,401 reviews)
"Good service and good people"
United States
ANGEL
The price is $80
$89 total
includes taxes & fees
Nov 23 - Nov 24
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

7. The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 12.8 km from Sanctuary
10.0 out of 10, Exceptional, (85 reviews)
"It was an amazing Stay, the rooms were incredible and beautiful, the location amazing!!! The Inn was very very good, all around, God willing we will definitely come back!!!"
United States
Ricardo E
The price is $176
$211 total
includes taxes & fees
Nov 10 - Nov 11
The Anchor Inn

8. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
18.1 km from Sanctuary
9.0 out of 10, Wonderful, (1,001 reviews)
"Very friendly staff pools are amazing and the rooms are very convenient and clean"
United States
Danny
The price is $146
$208 total
includes taxes & fees
Nov 15 - Nov 16
The Westin Cape Coral Resort At Marina Village

9. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
15.6 km from Sanctuary
8.6 out of 10, Excellent, (1,002 reviews)
"Very nice clean and very helpful staff"
United States
Matthew
The price is $223
$284 total
includes taxes & fees
Nov 22 - Nov 23
Marriott Sanibel Harbour Resort & Spa

10. Hideaway Waterfront Resort & Hotel

Hideaway Waterfront Resort & Hotel
2.0 star property
22.4 km from Sanctuary
10.0 out of 10, Exceptional, (1 review)
"Nice older property and the staff was extremely hospitable and helpful. Beautiful spaces and water features around the property. Convenient location as I needed to go on a boat trip from the marina close by."
United States
Dawn
The price is $100
$112 total
includes taxes & fees
Nov 8 - Nov 9
Hideaway Waterfront Resort & Hotel

11. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
19.3 km from Sanctuary
8.8 out of 10, Excellent, (1,001 reviews)
"The staff was very helpful with every question I had, really enjoyed our stay."
United States
Amy
The price is $102
$114 total
includes taxes & fees
Nov 15 - Nov 16
Residence Inn by Marriott Fort Myers Sanibel

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
23.9 km from Sanctuary
9.4 out of 10, Exceptional, (1,749 reviews)
"Breakfast was great. Staff was pleasant. Clean room and comfortable mattress. Great location too."
United States
LeAnn
The price is $100
$112 total
includes taxes & fees
Nov 11 - Nov 12
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

13. Casa Ybel Resort

Casa Ybel Resort
2.5 star property
Ybel, 11.6 km from Sanctuary
8.8 out of 10, Excellent, (480 reviews)
"We liked it because it was very close to the beach and pool area."
United States
Juan
The price is $265
$296 total
includes taxes & fees
Nov 8 - Nov 9
Casa Ybel Resort

14. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
22.6 km from Sanctuary
8.8 out of 10, Excellent, (1,000 reviews)
"Great hotel for the price. Central to dining, coffee, shopping, and the beach."
United States
Amy
The price is $96
$107 total
includes taxes & fees
Dec 3 - Dec 4
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

15. Dolphin Key Resort

Dolphin Key Resort
3.0 star property
23.8 km from Sanctuary
8.8 out of 10, Excellent, (1,166 reviews)
"Great staff Great environment"
United States
Patrick
The price is $94
$105 total
includes taxes & fees
Nov 22 - Nov 23
Dolphin Key Resort

16. White Orchid Apartments

White Orchid Apartments
2.0 star property
20 km from Sanctuary
8.4 out of 10, Very good, (58 reviews)
"Super clean, had everything you need, easy access and departure, good location."
United States
Laura
The price is $65
$105 total
includes taxes & fees
Nov 8 - Nov 9
White Orchid Apartments

17. Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
21.8 km from Sanctuary
8.8 out of 10, Excellent, (2,185 reviews)
"Nice place to stay. Great location"
United States
David
The price is $129
$166 total
includes taxes & fees
Dec 3 - Dec 4
Lani Kai Beachfront Resort

18. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
30.1 km from Sanctuary
8.8 out of 10, Excellent, (940 reviews)
"Very good breakfast friendly staff clean room comfortable bed"
United States
Clifford
The price is $79
$88 total
includes taxes & fees
Nov 22 - Nov 23
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

19. Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
20.2 km from Sanctuary
9.6 out of 10, Exceptional, (304 reviews)
"Great location very well kept clean will be back soon."
United States
Robby
The price is $60
$134 total
includes taxes & fees
Nov 9 - Nov 10
Matlacha on Shoreview

20. The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
21.5 km from Sanctuary
8.6 out of 10, Excellent, (1,849 reviews)
"Had various stays there before, but this was the BEST room. Location was terrific for us, pool & bar right outside the door, but away from the main Tiki Bar (where all the noise is). Will definitely ask for that room again on our next visit."
United States
Judith
The price is $91
$122 total
includes taxes & fees
Nov 16 - Nov 17
The Lighthouse Resort Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.
Off the Charts Inn & Out Island Resort
2.5 star property
9.6
Exceptional
165 reviews
View
Living area
The Anchor Inn
2.0 star property
10.0
Exceptional
85 reviews
View
A resort with a central pool, multiple lounge areas, and a beach view.
Tween Waters Island Resort & Spa
3.0 star property
8.6
Excellent
1,001 reviews
View
A resort with multiple-story buildings, palm trees, and a well-maintained lawn.
Sanibel Island Beach Resort
3.0 star property
9.2
Wonderful
2,415 reviews
View
A covered outdoor area with a table and chairs, a ceiling fan, and a view of a beach with palm trees and a boat.
Island Inn
3.5 star property
9.4
Exceptional
1,168 reviews
View

When is the best time to visit Sanibel?

Our prices for hotels in Sanibel are cheapest in October

Price trends for hotels in Sanibel

Pricing is based on two traveler single night rates
View properties in November
Currently viewing crowd sizes and weather for November.

November

High 25°C / low 20°C. Sunny most days.
25°
weather_sun
November, no crowd data, average high temperature 25 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
23°
weather_sun
December, no crowd data, average high temperature 23 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
18°
21°
weather_sun
January, no crowd data, average high temperature 21 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
23°
weather_sun
February, no crowd data, average high temperature 23 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
24°
weather_sun
March, no crowd data, average high temperature 24 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
18°
27°
weather_sun
April, no crowd data, average high temperature 27 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
29°
weather_sun
May, no crowd data, average high temperature 29 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
30°
weather_partly_sunny
June, no crowd data, average high temperature 30 degrees Celsius, average low temperature 26 degrees Celsius. Partly sunny.
26°
31°
weather_partly_sunny
July, no crowd data, average high temperature 31 degrees Celsius, average low temperature 27 degrees Celsius. Partly sunny.
27°
31°
weather_partly_sunny
August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 27 degrees Celsius. Partly sunny.
27°
30°
weather_partly_sunny
September, no crowd data, average high temperature 30 degrees Celsius, average low temperature 26 degrees Celsius. Partly sunny.
26°
29°
weather_sun
October, no crowd data, average high temperature 29 degrees Celsius, average low temperature 23 degrees Celsius. Sunny most days.
23°
Monthly weather averages (˚C)

Check out reviews of Sanctuary hotels guests love