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Clayton, St. Louis, Missouri, United States of America

Business Hotels in Clayton

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Business Hotels in Clayton

Enjoy the scenic views from the balcony with a black railing.

Banquet hall with high ceilings and elegant chandeliers, featuring a round table and multi-tiered wedding cake.

Enter a grand lobby with a high ceiling, ornate chandelier, and beautiful floral arrangement.

Two single beds with matching headboards and footboards, a desk with a computer and chair, and a shelf above the desk.

Clayton Plaza Hotel & Extended Stay

3.5 star property

Clayton

8.8 out of 10, Excellent, (2928)

8.8/10

Excellent

(2928)

The price is $105

$105

$122 total

includes taxes & fees

Aug 3 - Aug 4

Clayton Plaza Hotel & Extended Stay

Experience the Residence Inn's urban retreat, offering spacious rooms with large windows and balconies.

Relax in style with a fire pit surrounded by comfortable seating and a city view.

Two large beds with wooden frames and white bedding, a desk, chair, and flat-screen TV.

Relax in a spacious room with a large window offering a view of the outdoors, a comfortable sofa, and a flat-screen TV.

Residence Inn By Marriott St. Louis Clayton

3.0 star property

Clayton

9.2 out of 10, Wonderful, (163)

9.2/10

Wonderful

(163)

The price is $174

$174

$209 total

includes taxes & fees

Jul 20 - Jul 21

Residence Inn By Marriott St. Louis Clayton

Traditional Tudor-style building with a gabled roof and central entrance, featuring timber framing and a brick chimney.

Features a sleek open shelving unit, white toilet, and large mirror with a round frame.

Relax in a stylish room with a comfortable sofa, armchair, and neatly made bed, featuring a large window with a view.

Guests can dine or socialize in the shaded patio area, surrounded by tables, chairs, and decorative elements.

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

3.5 star property

Clayton

8.4 out of 10, Very Good, (565)

8.4/10

Very Good

(565)

The price is $122

$122

$145 total

includes taxes & fees

Jul 20 - Jul 21

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Relax by the warm fireplace in our inviting lounge area, featuring comfortable seating and a well-stocked bar.

Relax in this stylish lounge area with a round coffee table, armchairs, and a geometric abstract painting.

Spacious room with a dining area, staircase, and seating area featuring a long table and armchairs.

Enjoy a comfortable stay with a large window offering a view of the outdoors, a seating area, and a kitchen.

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3.0 star property

Clayton

9.0 out of 10, Wonderful, (858)

9.0/10

Wonderful

(858)

The price is $137

$137

$161 total

includes taxes & fees

Aug 3 - Aug 4

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Enjoy panoramic city views from this rooftop terrace, featuring a casual dining area and bar.

Enjoy a drink at the bar, where you can sit at the counter or at one of the tables.

Relax in a stylish lounge area with a brown leather sofa, armchairs, and a coffee table.

Two large beds with white linens, a desk, and a flat-screen TV.

AC Hotel St. Louis Clayton

3.0 star property

Clayton

9.2 out of 10, Wonderful, (100)

9.2/10

Wonderful

(100)

The price is $143

$143

$167 total

includes taxes & fees

Jul 17 - Jul 18

AC Hotel St. Louis Clayton

Relax by the pool surrounded by lush greenery and enjoy the serene atmosphere.

Enjoy a city view from the large window in this stylish room, featuring a flat-screen TV, comfortable sofa, and a coffee table.

Relax on the rooftop with a seating area, small table, and railing, surrounded by lush greenery and modern urban views.

Enjoy a sophisticated drink at the stylish bar with a round counter, surrounded by paneling and elegant decor.

Le Méridien St. Louis Clayton

4.0 star property

Clayton

8.8 out of 10, Excellent, (627)

8.8/10

Excellent

(627)

The price is $174

$174

$204 total

includes taxes & fees

Aug 3 - Aug 4

Le Méridien St. Louis Clayton

Stylish hotel building with a flat facade and evenly spaced windows, featuring a covered entrance and lush surroundings.

Two queen-sized beds with white linens and wooden headboards, a flat-screen TV, and a dresser.

Enjoy cooking in this well-equipped kitchen with a central island, stove, and ample counter space.

Enjoy casual outdoor dining and cooking in this patio area with a barbecue grill and comfortable seating.

Homewood Suites by Hilton St Louis - Galleria

3.0 star property

Clayton

8.0 out of 10, Very Good, (1004)

8.0/10

Very Good

(1004)

The price is $154

$154

$183 total

includes taxes & fees

Jul 20 - Jul 21

Homewood Suites by Hilton St Louis - Galleria

Dine al fresco with a view of the surrounding cityscape from this outdoor dining area.

Stroll through the landscaped grounds, bordered by greenery and potted plants, to the nearby Don Francisco building.

Two large beds with white linens, a flat-screen TV, and a desk with a chair, offering a city view.

Enjoy a sophisticated dining experience with a long bar and multiple seating options, surrounded by a high ceiling, hanging plants, and scenic views.

The Ritz-Carlton, St. Louis

5.0 star property

Clayton

9.2 out of 10, Wonderful, (538)

9.2/10

Wonderful

(538)

The price is $579

$579

$674 total

includes taxes & fees

Jul 13 - Jul 14

The Ritz-Carlton, St. Louis

Two beds with classic headboards and bedside tables, a wall-mounted TV, desk, and chair, and a window with curtains.

Relax in a spacious lounge area with a sectional sofa, ottomans, and a round table.

Relax by the pool surrounded by comfortable outdoor seating and enjoy the views from the adjacent building.

Stunning hotel entrance with a covered walkway leading to the main doors.

Drury Inn & Suites St. Louis Fairview Heights

3.0 star property

Fairview Heights

9.2 out of 10, Wonderful, (1015)

9.2/10

Wonderful

(1015)

The price is $93

$93

$106 total

includes taxes & fees

Jul 27 - Jul 28

Drury Inn & Suites St. Louis Fairview Heights

Relax in comfort with a large bed, two nightstands, and a city skyline view.

Enjoy a functional stay with a flat-screen TV, microwave, and refrigerator, perfect for travelers seeking convenience.

Classic lobby with a reception desk, comfortable seating area, and a large window.

Situated in a well-maintained area, this hotel features a modern architectural design with a symmetrical facade and central entrance.

Super 8 by Wyndham Fairview Heights-St. Louis

2.0 star property

Fairview Heights

6.8 out of 10, (1005)

6.8/10

(1005)

The price is $61

$61

$69 total

includes taxes & fees

Jul 20 - Jul 21

Super 8 by Wyndham Fairview Heights-St. Louis

Welcome to Country Inn & Suites, featuring a sleek entrance with a glass door and brick pillars.

Relax in a cozy seating area with a fireplace and flat-screen TV, featuring a kitchen with a coffee machine and appliances.

Compact room with a wardrobe, kitchenette, and radiator, ideal for short stays.

Two single beds with bedside tables and lamps, a television, and a dresser with a trash bin.

Country Inn & Suites by Radisson, Fairview Heights, IL

3.0 star property

Fairview Heights

7.2 out of 10, Good, (755)

7.2/10

Good

(755)

The price is $80

$80

$90 total

includes taxes & fees

Jul 27 - Jul 28

Country Inn & Suites by Radisson, Fairview Heights, IL

Relax in our spacious lobby with comfortable seating and a view of the outdoors.

Relax and unwind by the pool, surrounded by lounge chairs and tables.

Two comfortable beds with headboards and bedside tables, each made with crisp linens, and a decorative blanket.

Experience the charm of this beautifully landscaped garden, surrounded by a modern building with large windows and a welcoming atmosphere.

Drury Inn & Suites St. Louis Collinsville

3.0 star property

Eastport

9.6 out of 10, Exceptional, (1008)

9.6/10

Exceptional

(1008)

The price is $111

$111

$128 total

includes taxes & fees

Jul 20 - Jul 21

Drury Inn & Suites St. Louis Collinsville

Guests can check in at the reception desk, surrounded by artwork and comfortable seating.

Hotel entrance with a covered area supported by columns, offering a convenient parking space and access to the building.

Convenient parking with charging station and metal door.

Relax in a stylish room with a large bed, dark headboard, and two bedside tables, each with a lamp and phone.

Americas Best Value Inn Collinsville St. Louis

2.0 star property

Collinsville

6.6 out of 10, (914)

6.6/10

(914)

The price is $71

$71

$82 total

includes taxes & fees

Jul 13 - Jul 14

Americas Best Value Inn Collinsville St. Louis

Relax in comfort with a large bed, bedside tables, and a cityscape artwork above.

Relax in comfort with a large bed, bedside table, and cozy seating area.

Experience the comfort of this two-story hotel with a flat roof, offering a convenient parking area and a covered outdoor seating space.

Welcome to the reception area, where guests can check in and access hotel information on the digital screen.

Days Inn by Wyndham Collinsville/St. Louis

2.5 star property

Eastport

7.2 out of 10, Good, (1002)

7.2/10

Good

(1002)

The price is $60

$60

$69 total

includes taxes & fees

Aug 10 - Aug 11

Days Inn by Wyndham Collinsville/St. Louis

Relax in a cozy retreat with a comfortable bed, city views, and a seating area.

Welcome to this two-story hotel with a convenient parking lot and easy access to the entrance.

Enjoy a comfortable stay with a flat-screen TV, desk, and microwave in this well-appointed room.

Enjoy meals and meetings in this room with a kitchen area, dining table, and comfortable seating.

Super 8 by Wyndham Collinsville St. Louis

2.0 star property

Eastport

7.0 out of 10, Good, (1005)

7.0/10

Good

(1005)

The price is $64

$64

$74 total

includes taxes & fees

Aug 10 - Aug 11

Super 8 by Wyndham Collinsville St. Louis

Two single beds with white bedding and black pillows, a desk, flat-screen TV, and a wardrobe.

Welcome to our hotel, featuring a covered entryway with stone pillars and ample parking.

Stay fit on the go with our fully equipped gym featuring treadmills, stationary bikes, and a bench.

Relax in our inviting lobby, featuring a comfortable bench and ottoman, alongside a reception desk and snack display.

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

3.0 star property

Eastport

7.2 out of 10, Good, (1002)

7.2/10

Good

(1002)

The price is $86

$86

$99 total

includes taxes & fees

Aug 10 - Aug 11

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Enjoy a meal or snack in our communal breakfast area, featuring a selection of food and beverages.

La Quinta offers a striking symmetrical facade with a central entrance and beautifully landscaped surroundings.

Relax in the stylish lobby with a long table and comfortable seating.

Stay fit on the go with our well-equipped gym featuring treadmills, elliptical trainers, and strength training equipment.

La Quinta Inn & Suites by Wyndham Pontoon Beach

3.0 star property

Granite City

7.8 out of 10, Good, (467)

7.8/10

Good

(467)

The price is $105

$105

$121 total

includes taxes & fees

Jul 27 - Jul 28

La Quinta Inn & Suites by Wyndham Pontoon Beach

Cozy retreat with a traditional fireplace, leather sofas, and a modern TV.

Relax in the hotel lobby with a beverage refrigerator stocked with drinks and snacks, a TV, and comfortable seating.

Relax in a spacious room with a large bathtub, seating area, and flat-screen TV.

Relax in this inviting room with a large bed, two bedside tables, a comfortable chair, and a TV.

Best Western Plus Pontoon Beach

3.0 star property

Granite City

8.6 out of 10, Excellent, (693)

8.6/10

Excellent

(693)

The price is $94

$94

$105 total

includes taxes & fees

Jul 27 - Jul 28

Best Western Plus Pontoon Beach

Check-in area features a mosaic tile design, computer stations, and a mounted TV.

Welcome to CQ Hotel, a stylish hotel with a central entrance and parking available.

Experience the excitement of gaming at our casino, where tables and chairs invite you to play.

Enjoy the city view from the comfort of your room, with a prominent bridge and high-rise buildings visible through the large window.

Casino Queen Hotel

3.0 star property

East St. Louis

7.8 out of 10, Good, (1840)

7.8/10

Good

(1840)

The price is $99

$99

$115 total

includes taxes & fees

Jul 20 - Jul 21

Casino Queen Hotel

Experience the excitement of the casino floor, where gaming tables and slot machines come alive.

Experience the ultimate poker destination with tables, bold graphics, and a lively atmosphere.

Relax in the inviting lobby, surrounded by a central water feature and comfortable seating areas.

Relax in a spacious seating area with multiple sofas and chairs, perfect for unwinding or socializing.

HoteLumiere at the Arch

4.0 star property

Downtown St. Louis

6.6 out of 10, (1001)

6.6/10

(1001)

The price is $110

$110

$152 total

includes taxes & fees

Aug 11 - Aug 12

HoteLumiere at the Arch

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in St. Louis

Busch Stadium

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

See propertiesSee properties in Busch Stadium

Busch Stadium

St. Louis Union Station

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed art scene or attend a baseball game.

See propertiesSee properties in St. Louis Union Station

St. Louis Union Station

Gateway Arch

Find out about the history of Gateway Arch, one of the top monuments in St. Louis. Experience the area's acclaimed art scene or attend a baseball game.

See propertiesSee properties in Gateway Arch

Gateway Arch

St. Louis Zoo

Why not visit the animals who live at St. Louis Zoo and see why this is a popular attraction in St. Louis? Amble around the area's lush forest or attend a sporting event.

See propertiesSee properties in St. Louis Zoo

St. Louis Zoo

City Museum

You can spend an afternoon studying the exhibits at City Museum during your trip to St. Louis. Experience the area's fascinating museums and acclaimed theater scene.

See propertiesSee properties in City Museum

City Museum

Forest Park

After visiting Forest Park, make a plan to see the other sights and activities in St. Louis. Discover the area's entertainment choices and shops.

See propertiesSee properties in Forest Park

Forest Park

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3 Star Hotels in Clayton

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Business Hotels in Central West End

Forest Park Hotel by MDR
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Aloft St. Louis Cortex
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
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Live by Loews - St.Louis
The Cheshire
Hilton Pennywell St. Louis at the Arch
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Best Western St. Louis Inn
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Best Western Plus St. Louis Airport Hotel
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St. Louis Airport Hotel
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Drury Inn & Suites St. Louis Forest Park
Travelodge by Wyndham St. Louis
Drury Inn & Suites St. Louis Airport
Elimwood Hotel, A Ramada by Wyndham
Fairfield Inn & Suites by Marriott St. Louis Downtown
Best Western Plus St. Louis West-Westport
Americas Best Value Inn St. Louis South
Marriott St. Louis Airport
Sonesta ES Suites St. Louis - Chesterfield
Best Western Plus Pontoon Beach
Drury Inn & Suites Southwest St. Louis
Drury Inn & Suites St. Louis Brentwood
Pear Tree Inn St. Louis Convention Center
Hilton St. Louis Airport
Best Western St. Louis Airport North Hotel & Suites
Missouri Athletic Club
Element St. Louis Midtown
Hampton Inn & Suites St. Louis at Forest Park
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave
HoteLumiere at the Arch

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Business Hotels in Clayton

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Business Hotels in Clayton

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

Top landmarks in St. Louis

Busch Stadium

Keep exploring

Keep exploring

Most popular destinations

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