Hotels in Upstate South Carolina

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Where to stay in Upstate South Carolina?

Extended Stay America Premier Suites - Greenville - Spartanburg - I-85

2.5 star property
8.6 out of 10, Excellent, (167)
The price is $79
$88 total
includes taxes & fees
Aug 22 - Aug 23
Extended Stay America Premier Suites - Greenville - Spartanburg - I-85

Baymont by Wyndham Duncan/Spartanburg

2.5 star property
7.0 out of 10, Good, (404)
The price is $78
$87 total
includes taxes & fees
Jul 24 - Jul 25
Baymont by Wyndham Duncan/Spartanburg

Microtel Inn by Wyndham Duncan/Spartanburg

2.0 star property
7.2 out of 10, Good, (508)
The price is $70
$77 total
includes taxes & fees
Aug 21 - Aug 22
Microtel Inn by Wyndham Duncan/Spartanburg

Sleep Inn

2.5 star property
5.8 out of 10, (489)
The price is $66
$73 total
includes taxes & fees
Aug 15 - Aug 16
Sleep Inn

Comfort Suites At WestGate Mall

2.5 star property
8.2 out of 10, Very Good, (1004)
The price is $93
$105 total
includes taxes & fees
Aug 3 - Aug 4
Comfort Suites At WestGate Mall

Quality Inn Duncan - Spartanburg West

2.5 star property
7.6 out of 10, Good, (343)
The price is $68
$76 total
includes taxes & fees
Aug 21 - Aug 22
Quality Inn Duncan - Spartanburg West

ECHO Suites Extended Stay by Wyndham Spartanburg

2.0 star property
8.0 out of 10, Very Good, (182)
The price is $94
$106 total
includes taxes & fees
Jul 27 - Jul 28
ECHO Suites Extended Stay by Wyndham Spartanburg

Super 8 by Wyndham Greer/Spartanburg Area

2.0 star property
7.2 out of 10, Good, (488)
The price is $63
$71 total
includes taxes & fees
Jul 26 - Jul 27
Super 8 by Wyndham Greer/Spartanburg Area

Red Roof Inn & Suites Duncan

2.0 star property
6.8 out of 10, (333)
The price is $67
$75 total
includes taxes & fees
Jul 27 - Jul 28
Red Roof Inn & Suites Duncan

WoodSpring Suites Spartanburg - Duncan

2.5 star property
6.4 out of 10, (225)
The price is $69
$78 total
includes taxes & fees
Jul 24 - Jul 25
WoodSpring Suites Spartanburg - Duncan

stayAPT Suites Greenville Greer BMW

3.0 star property
8.6 out of 10, Excellent, (82)
The price is $129
$146 total
includes taxes & fees
Jul 24 - Jul 25
stayAPT Suites Greenville Greer BMW

Days Inn by Wyndham Simpsonville

2.0 star property
7.2 out of 10, Good, (376)
The price is $66
$73 total
includes taxes & fees
Aug 1 - Aug 2
Days Inn by Wyndham Simpsonville

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (562)
The price is $187
$240 total
includes taxes & fees
Aug 12 - Aug 13
Hotel Hartness

Woodspring Suites Greenville Airport

2.5 star property
8.6 out of 10, Excellent, (121)
The price is $72
$79 total
includes taxes & fees
Jul 24 - Jul 25
Woodspring Suites Greenville Airport

Best Western Spartanburg Northwest

3.0 star property
8.2 out of 10, Very Good, (759)
The price is $87
$98 total
includes taxes & fees
Jul 27 - Jul 28
Best Western Spartanburg Northwest

Days Inn by Wyndham Spartanburg Waccamaw

2.0 star property
7.2 out of 10, Good, (708)
The price is $66
$74 total
includes taxes & fees
Jul 26 - Jul 27
Days Inn by Wyndham Spartanburg Waccamaw

Hampton Inn & Suites Greenville Airport, SC

2.5 star property
9.2 out of 10, Wonderful, (918)
The price is $101
$111 total
includes taxes & fees
Aug 15 - Aug 16
Hampton Inn & Suites Greenville Airport, SC

Red Roof Inn Spartanburg – I-26

2.0 star property
7.0 out of 10, Good, (718)
The price is $70
$77 total
includes taxes & fees
Aug 12 - Aug 13
Red Roof Inn Spartanburg – I-26

MainStay Suites Greenville Airport

2.5 star property
7.6 out of 10, Good, (567)
The price is $80
$88 total
includes taxes & fees
Aug 1 - Aug 2
MainStay Suites Greenville Airport

Quality Inn

2.0 star property
7.0 out of 10, Good, (794)
The price is $60
$66 total
includes taxes & fees
Aug 7 - Aug 8
Quality Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Upstate South Carolina, SC

Showing deals for:Aug 1 - Aug 3

Top landmarks in Upstate South Carolina

Learn more about Upstate South Carolina

Upstate South Carolina is applauded for its cultural attractions such as Heritage Park and Roper Mountain Science Center.

Greenville - Spartanburg showing a sunset, tranquil scenes and mountains
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Check out reviews of Upstate South Carolina hotels guests love

Frequently asked questions

Can I book a refundable hotel in Upstate South Carolina?
If you're looking for the flexibility to change your travel plans to Upstate South Carolina, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Upstate South Carolina if I want a vacation rental instead of a traditional hotel?
If you're looking for a good alternative to a hotel, review our selection of 1073 vacation homes. In addition, there are 111 apartments and 92 condos.
Why should I book my Upstate South Carolina hotel through Hotels.com?
There are lots of reasons to book your Upstate South Carolina trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.