Hotels in Mesa

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A restaurant interior with wooden beams, antler decorations, and a long wooden bench.

A bar area with wooden bar stools, a central bar counter, and shelves stocked with bottles and glasses.

A bedroom with a wooden headboard, a bed with a green bedspread, two bedside tables with lamps, and a small wooden desk with a plant.

A building with a porch, wooden steps, and two large wheels on the facade.

1. Wagon Wheel Restaurant Bar and Motel

Mesa

$170

$179 total

includes taxes & fees

Oct 20 - Oct 21

A hotel with a swimming pool, lounge chairs, and a view of a mountain.

A vineyard estate with multiple buildings, including a large house with a green roof and several smaller structures.

A covered porch with white rocking chairs, a wooden barrel, and a view of a mountain.

A formal dining setting with a table set for four, including wine glasses and a vase of red roses.

2. Wine Country Inn Palisade

Palisade

$152

$169 total

includes taxes & fees

Nov 1 - Nov 2

Two people sitting on chairs outside a building with green doors, one holding a bottle.

A room with a sofa, a dining table, chairs, a potted plant, a wall-mounted plant, and a framed picture.

Two people sitting on a bed with a laptop and a book.

A room with a dark blue wall, a brown sofa, a wicker chair, a small side table with a plant, and a hanging macrame piece.

3. The Alpine Motel

Collbran

$122

$131 total

includes taxes & fees

Oct 20 - Oct 21

A rustic cabin with a garage, surrounded by a gravel driveway, a large tree with yellow leaves, and a rocky cliff in the background.

A modern bedroom with a large bed, a TV mounted on the wall, a bathroom with a shower curtain, and a small seating area with a chair.

A patio with a lounge chair and a table, a tree, and a view of the landscape.

A rustic building with a red exterior and white walls, a gravel driveway, and a large tree in front.

4. The Homestead

Palisade

$207

$218 total

includes taxes & fees

Nov 1 - Nov 2

A sign for the Spoke and Vine Motel with a bicycle symbol, set against a mountainous backdrop.

A metal cart with shelves holding mugs, a kettle, wine bottles, and fruit.

A bar area with a bicycle wheel decoration, a bar menu, and shelves with bottles and snacks.

A covered outdoor seating area with wooden benches and a round table.

5. Spoke and Vine Motel

Palisade

$152

$169 total

includes taxes & fees

Oct 27 - Oct 28

A wooden deck with a view of a forest and a lake.

A spacious restaurant with wooden tables and chairs, a chandelier, and a mural on the wall.

A rustic interior with a wooden dining table, a striped armchair, a gray sofa, and a wooden cabinet.

A cozy cabin interior with a wooden dining table, a sofa, and a kitchen area including a stove and cabinets.

6. Grand Mesa Lodge

Cedaredge

$122

$133 total

includes taxes & fees

Nov 1 - Nov 2

A wooden deck with a table and chairs, a stone wall, and a view of a lake surrounded by trees.

A wooden cabin room with two beds, a small desk, and a stone archway.

A log cabin with large windows, surrounded by snow.

A long wooden table with a polished surface, surrounded by chairs, in a rustic room with wooden walls and a brick fireplace.

7. Alexander lake lodge

Cedaredge

$113

$122 total

includes taxes & fees

Oct 20 - Oct 21

A spacious living area with a high ceiling, a wooden coffee table, a leather sofa, and a staircase leading to an upper level.

A spacious living room with a stone fireplace, a leather sofa, a desk with a computer, and a large mirror.

A hotel room with a large bed, a TV, a dresser, and a door.

An indoor swimming pool with clear water, a 3-foot depth marker, and a lifeguard stand.

8. Best Western Grande River Inn & Suites

Clifton

$110

$117 total

includes taxes & fees

Oct 26 - Oct 27

A rustic interior with a staircase, wooden beams, and potted plants.

A kitchen with wooden cabinets, a large island, stainless steel appliances, and a window providing natural light.

A stone-floored patio with a bed, a chair, and a table.

A modern building with large windows, a staircase, and a solar panel.

9. Maison de Terre

Cedaredge

$140

$179 total

includes taxes & fees

Oct 22 - Oct 23

A parking lot with a red SUV, a blue truck, and a white car.

A reception area with a wooden counter, a coffee bar, and a large landscape painting on the wall.

A gym with treadmills, weight machines, and exercise balls.

A hotel room with a bed, a desk, a television, and a window with curtains.

10. Western Slope suites

Parachute

$72

$81 total

includes taxes & fees

Nov 1 - Nov 2

A reception desk at the Grand River Hotel with a stone wall backdrop and a large illuminated sign.

A cozy living room with a stone accent wall, leather sofa, patterned chairs, and horse-themed artwork.

A Grand River Hotel with a modern design, featuring a prominent entrance and a parking lot.

A cozy living room with a fireplace, leather sofa, and horse-themed artwork.

11. Grand River Hotel

Parachute

$65

$74 total

includes taxes & fees

Nov 1 - Nov 2

A restaurant with stone walls and large windows, outdoor wooden tables and chairs, and a garden with colorful flowers.

A building with a stone facade and a wooden fence adorned with colorful flowers.

An indoor swimming pool with a mural of a desert landscape, a ceiling with skylights, and a seating area with chairs.

A bar area with a wooden interior, bar stools, and a sign for Cook's Goldblume beer.

12. Grand Vista Hotel

Horizon Drive District

$79

$91 total

includes taxes & fees

Nov 1 - Nov 2

A reception desk with a clock, a computer, and a potted plant.

A corridor with tiled flooring, several round tables with chairs, and a black refrigerator.

A hotel hallway with a patterned carpet, doors on both sides, and a tiled ceiling.

A modern office space with a desk, office chair, and a large landscape painting on the wall.

13. Ramada by Wyndham Grand Junction

Horizon Drive District

$76

$87 total

includes taxes & fees

Oct 20 - Oct 21

A breakfast bar with a variety of food items, including fruits, pastries, and dairy products.

A modern lounge area with a leather sofa, two patterned side tables, a flat-screen TV mounted on a textured wall, and a built-in fireplace.

A reception area with a large mural of a desert landscape, two reception desks with modern design, and a patterned wall to the left.

A hot tub surrounded by lounge chairs and a pool, with a building in the background.

14. La Quinta Inn & Suites by Wyndham Grand Junction

Horizon Drive District

$79

$91 total

includes taxes & fees

Nov 15 - Nov 16

A reception area with a wooden reception desk, a framed welcome sign, and a no-smoking sign.

A laundry area with stacked washers and dryers, a window with blinds, and wall-mounted artwork.

A hotel room with two beds, a nightstand with a lamp, and two framed pictures on the wall.

A clean, modern dining area with a wooden counter and chairs.

15. Super 8 by Wyndham Grand Junction Colorado

Horizon Drive District

$60

$68 total

includes taxes & fees

Oct 25 - Oct 26

A spacious room with a large window, a red armchair, a wooden desk, and a lamp.

A hotel room with a green sofa, a small table with a lamp, a phone, a mirror, and a red carpeted floor.

A buffet area with a wooden counter, a glass display case, and a Coca-Cola machine.

A hotel room with a bed, a desk with a computer, a mirror, a lamp, and a telephone.

16. Quality Inn Grand Junction near University

Horizon Drive District

$79

$90 total

includes taxes & fees

Nov 14 - Nov 15

A large indoor swimming pool with a hot tub, surrounded by lounge chairs and a tiled floor.

A hotel lobby with a reception desk, seating area, and fireplace.

A Grand Vista Hotel with a covered entrance, multiple windows, and a well-lit facade.

A hotel room with a large bed, two bedside tables with lamps, a window with curtains, and a view of mountains.

17. Grand Vista Hotel Parachute

Parachute

$77

$88 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a central seating area, a reception desk, and a digital information screen.

A modern lobby with a sectional sofa, round ottomans, and a red reception desk.

An outdoor patio area with multiple wooden tables and chairs, some with red umbrellas.

A hotel room with a desk, office chair, sofa, and a TV on a wooden cabinet.

18. Doubletree Hotel Grand Junction

Horizon Drive District

$87

$100 total

includes taxes & fees

Nov 7 - Nov 8

19. Camp Eddy

Pear Park

$60

$123 total

includes taxes & fees

Nov 9 - Nov 10

A spacious living area with a staircase, two grey armchairs, a round coffee table, and a view of the outside.

A spacious dining area with multiple tables and chairs, a kitchen in the background, and a modern ceiling design.

An indoor swimming pool with a lifeguard chair, pool ladder, and a seating area with tables and chairs.

A hotel room with a large bed, a desk, a chair, a small table, and a wall-mounted heater.

20. Comfort Inn Grand Junction I-70

Horizon Drive District

$78

$90 total

includes taxes & fees

Nov 15 - Nov 16

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Go beyond your typical stay in Mesa

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Cottage

Hot tub

Pool

Family friendly

Our prices for hotels in Mesa are cheapest in September

Top landmarks in Mesa

Powderhorn Resort

8.6/10 (106 reviews)

Skiers and snowboarders might want to test out the slopes at Powderhorn Resort, a skiing spot located 6.7 mi (10.8 km) from central Mesa.

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Learn more about Mesa

Mesa is well-known for its attractions such as Powderhorn Resort and Grand Mesa National Forest.

See all hotels in Mesa

Ancient cliff dwellings carved into a canyon wall.

Check out reviews of Mesa hotels guests love

Wine Country Inn Palisade

10/10 Excellent

"Great place to stay 3 nights for a wedding in Palisade. Very central location to all the wedding activities and beautiful grounds. Staff was very helpful and kind. Shout out to the very hard-working woman who was running breakfast each morning. It was very busy and she kept up with everything, She deserves a raise!"

Grand Vista Hotel Parachute

10/10 Excellent

"everyone was great! would stay there again"

La Quinta Inn & Suites by Wyndham Grand Junction

8/10 Good

"The room was nice and clean, we. Just had one problem, the shower faucet. We had to call the desk clerk to help us shut it off. The sweet desk clerk Michelle, bless her heart came to our room in her wheelchair and helped us turn it off, that's dedication! A keeper! She deserves a raise!"

Clarion Inn Grand Junction

8/10 Good

"Charming place. Happy to visit again."

Quality Inn Grand Junction near University

10/10 Excellent

"Staff was super friendly and welcoming. The breakfast was really good, and the rooms were clean."

Camp Eddy

8/10 Good

"Interesting place, we rented a tiny house and it was indeed tiny, especially with 2 dogs. The location was great if you go to a concert. The monument and Grand Mesa are close."

Ville 718

10/10 Excellent

"Awesome"

Grand River Hotel

10/10 Excellent

"Huge thanks to the front desk team for taking care of my booking. They were super helpful!"

Super 8 by Wyndham Grand Junction Colorado

10/10 Excellent

"Good place to halt for and breakfast included as well"

Frequently asked questions

What accommodations do travelers like in Mesa?

Guests like Wagon Wheel Restaurant Bar and Motel and Powderhorn Lodging.

Can I book a refundable hotel in Mesa?

If you need the flexibility to change your travel plans to Mesa, most properties offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Mesa if I want a vacation home instead of a hotel?

Browse 10 vacation homes on our site. You can also book one of the 13 cabins for your stay.

What will the weather in Mesa be like during my vacation?

July and August are typically the warmest months in Mesa when the average temp is 69°F. January and December are the coldest months when the average temperature is 27°F. March and December are the months with the most rain.

Why should I book my Mesa hotel with Hotels.com?

There are lots of reasons to book your Mesa trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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Book Hotels in Mesa on Hotels.com

Hotels in Mesa

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Mesa?

1. Wagon Wheel Restaurant Bar and Motel

2. Wine Country Inn Palisade

3. The Alpine Motel

4. The Homestead

5. Spoke and Vine Motel

6. Grand Mesa Lodge

7. Alexander lake lodge

8. Best Western Grande River Inn & Suites

9. Maison de Terre

10. Western Slope suites

11. Grand River Hotel

12. Grand Vista Hotel

13. Ramada by Wyndham Grand Junction

14. La Quinta Inn & Suites by Wyndham Grand Junction

15. Super 8 by Wyndham Grand Junction Colorado

16. Quality Inn Grand Junction near University

17. Grand Vista Hotel Parachute

18. Doubletree Hotel Grand Junction

19. Camp Eddy

20. Comfort Inn Grand Junction I-70

Go beyond your typical stay in Mesa

Price trends for hotels in Mesa

Typical weather for Mesa

Top landmarks in Mesa

Powderhorn Resort

Learn more about Mesa

Check out reviews of Mesa hotels guests love

Wine Country Inn Palisade

Grand Vista Hotel Parachute

La Quinta Inn & Suites by Wyndham Grand Junction

Clarion Inn Grand Junction

Quality Inn Grand Junction near University

Camp Eddy

Ville 718

Grand River Hotel

Super 8 by Wyndham Grand Junction Colorado

Frequently asked questions

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