Hotels in Mesa

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Sep 2 - Sep 3
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Sep 3 - Sep 4
This weekend
Sep 4 - Sep 6
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Sep 11 - Sep 13

Top 5 hotels in Mesa at a glance

  1. Wagon Wheel Restaurant Bar and Motel — 3-star hotel in Mesa. Guest rating: 8.8/10 — Excellent.
  2. Wine Country Inn Palisade — 3.5-star hotel in Palisade. Guest rating: 9.6/10 — Exceptional.
  3. Best Western Grande River Inn & Suites — 2.5-star hotel in Clifton. Guest rating: 8.8/10 — Excellent.
  4. Grand Mesa Lodge — 2-star hotel in Cedaredge. Guest rating: 8.0/10 — Very Good.
  5. The Homestead — 4.5-star hotel in Palisade. Guest rating: 10/10 — Exceptional.

Where to stay in Mesa?

A restaurant interior with wooden beams, antler decorations, and a long wooden bench.
A bar area with wooden bar stools, a central bar counter, and shelves stocked with bottles and glasses.
A bedroom with a wooden headboard, a bed with a green bedspread, two bedside tables with lamps, and a small wooden desk with a plant.
A building with a porch, wooden steps, and two large wheels on the facade.

Wagon Wheel Restaurant Bar and Motel

Wagon Wheel Restaurant Bar and Motel
Mesa
Wagon Wheel Restaurant Bar and Motel
A hotel with a swimming pool, lounge chairs, and a view of a mountain.
A vineyard estate with multiple buildings, including a large house with a green roof and several smaller structures.
A formal dining setting with a table set for four, including wine glasses and a vase of red roses.
A covered porch with white rocking chairs, a wooden barrel, and a view of a mountain.

Wine Country Inn Palisade

Wine Country Inn Palisade
Palisade
Wine Country Inn Palisade
A spacious living area with a high ceiling, a wooden coffee table, a leather sofa, and a staircase leading to an upper level.
A spacious living room with a stone fireplace, a leather sofa, a desk with a computer, and a large mirror.
A hotel room with a large bed, a TV, a dresser, and a door.

Best Western Grande River Inn & Suites

Best Western Grande River Inn & Suites
Clifton
Best Western Grande River Inn & Suites
A wooden deck with a view of a forest and a lake.
A cozy cabin interior with a wooden dining table, a sofa, and a kitchen area including a stove and cabinets.
A rustic interior with a wooden dining table, a striped armchair, a gray sofa, and a wooden cabinet.
A spacious restaurant with wooden tables and chairs, a chandelier, and a mural on the wall.

Grand Mesa Lodge

Grand Mesa Lodge
Cedaredge
Grand Mesa Lodge
A rustic cabin with a garage, surrounded by a gravel driveway, a large tree with yellow leaves, and a rocky cliff in the background.
A patio with two lounge chairs and a wooden table, overlooking a grassy area with autumn foliage and distant mountains.
A modern bedroom with a large bed, a TV mounted on the wall, a bathroom with a shower curtain, and a small seating area with a chair.
A patio with a lounge chair and a table, a tree, and a view of the landscape.

The Homestead

The Homestead
Palisade
The Homestead
Two people sitting on chairs outside a building with green doors, one holding a bottle.
A room with a dark blue wall, a brown sofa, a wicker chair, a small side table with a plant, and a hanging macrame piece.
Two people sitting on a bed with a laptop and a book.
A green door with the number 3, two brown chairs, and a potted plant.

The Alpine Motel

The Alpine Motel
Collbran
The Alpine Motel
A sign for the Spoke and Vine Motel with a bicycle symbol, set against a mountainous backdrop.
A bar area with a bicycle wheel decoration, a bar menu, and shelves with bottles and snacks.
A covered outdoor seating area with wooden benches and a round table.
A dining area with a wooden table and chairs, a patterned rug, and pendant lighting.

Spoke and Vine Motel

Spoke and Vine Motel
Palisade
Spoke and Vine Motel
A rustic interior with a staircase, wooden beams, and potted plants.
A kitchen with wooden cabinets, a large island, stainless steel appliances, and a window providing natural light.
A room with a bed, a desk, a chair, a table, and a view through a glass door to the outside.
A stone-floored patio with a bed, a chair, and a table.

Maison de Terre

Maison de Terre
Cedaredge
Maison de Terre
A parking lot with a red SUV, a blue truck, and a white car.
A reception area with a wooden counter, a coffee bar, and a large landscape painting on the wall.
A hotel room with a bed, a desk, a television, and a window with curtains.
A gym with treadmills, weight machines, and exercise balls.

Western Slope suites

Western Slope suites
Parachute
Western Slope suites
A reception desk at the Grand River Hotel with a stone wall backdrop and a large illuminated sign.
A Grand River Hotel with a modern design, featuring a prominent entrance and a parking lot.
A cozy living room with a fireplace, leather sofa, and horse-themed artwork.
A cozy living room with a stone accent wall, leather sofa, patterned chairs, and horse-themed artwork.

Grand River Hotel

Grand River Hotel
Parachute
Grand River Hotel
A large indoor swimming pool with a hot tub, surrounded by lounge chairs and a tiled floor.
A hotel lobby with a reception desk, seating area, and fireplace.
A Grand Vista Hotel with a covered entrance, multiple windows, and a well-lit facade.
An outdoor patio with stone walls, wooden benches, and a fire pit.

Grand Vista Hotel Parachute

Grand Vista Hotel Parachute
Parachute
Grand Vista Hotel Parachute
A hotel room with a wooden floor, a sofa, a small table with a lamp, a bathroom with a bathtub, and a window with curtains.
A circular fire pit surrounded by a brick border, set in a gravel area with a grassy background.
An indoor swimming pool with a tiled edge, a lifeguard chair, and a door with an exit sign.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

Stay Wise Inn Cedaredge

Stay Wise Inn Cedaredge
Cedaredge
Stay Wise Inn Cedaredge
A spacious room with a large window, a red armchair, a wooden desk, and a lamp.
A hotel room with a green sofa, a small table with a lamp, a phone, a mirror, and a red carpeted floor.
A buffet area with a wooden counter, a glass display case, and a Coca-Cola machine.
A hotel room with a bed, a desk with a computer, a mirror, a lamp, and a telephone.

Quality Inn Grand Junction near University

Quality Inn Grand Junction near University
Horizon Drive District
Quality Inn Grand Junction near University
A spacious living area with a staircase, two grey armchairs, a round coffee table, and a view of the outside.
A hotel room with a large bed, a desk, a chair, a small table, and a wall-mounted heater.
An indoor swimming pool with a lifeguard chair, pool ladder, and a seating area with tables and chairs.
A spacious dining area with multiple tables and chairs, a kitchen in the background, and a modern ceiling design.

Comfort Inn Grand Junction I-70

Comfort Inn Grand Junction I-70
Horizon Drive District
Comfort Inn Grand Junction I-70
A breakfast bar with a variety of food items, including fruits, pastries, and dairy products.
A modern lounge area with a leather sofa, two patterned side tables, a flat-screen TV mounted on a textured wall, and a built-in fireplace.
A reception area with a large mural of a desert landscape, two reception desks with modern design, and a patterned wall to the left.
A hot tub surrounded by lounge chairs and a pool, with a building in the background.

La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction
Horizon Drive District
La Quinta Inn & Suites by Wyndham Grand Junction
A reception desk with a clock, a computer, and a potted plant.
A hotel hallway with a patterned carpet, doors on both sides, and a tiled ceiling.
A corridor with tiled flooring, several round tables with chairs, and a black refrigerator.
A modern office space with a desk, office chair, and a large landscape painting on the wall.

Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction
Horizon Drive District
Ramada by Wyndham Grand Junction
A restaurant with stone walls and large windows, outdoor wooden tables and chairs, and a garden with colorful flowers.
A building with a stone facade and a wooden fence adorned with colorful flowers.
A bar area with a wooden interior, bar stools, and a sign for Cook's Goldblume beer.
An indoor swimming pool with a mural of a desert landscape, a ceiling with skylights, and a seating area with chairs.

Grand Vista Hotel

Grand Vista Hotel
Horizon Drive District
Grand Vista Hotel
A reception area with a wooden reception desk, a framed welcome sign, and a no-smoking sign.
A rectangular swimming pool with a blue tiled edge, surrounded by white lounge chairs and a metal fence.
A clean, modern dining area with a wooden counter and chairs.
A laundry area with stacked washers and dryers, a window with blinds, and wall-mounted artwork.

Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado
Horizon Drive District
Super 8 by Wyndham Grand Junction Colorado
A golf course with a large green, sand bunkers, and a rocky hill in the background.
Rockslide Brewery with outdoor seating and a brick facade.
A Holiday Inn & Suites building with a modern design, featuring a prominent entrance and a stone facade.
A large indoor swimming pool with clear blue water, surrounded by walls with tiled patterns and a tiled floor.

Holiday Inn & Suites Grand Junction-Airport by IHG

Holiday Inn & Suites Grand Junction-Airport by IHG
Horizon Drive District
Holiday Inn & Suites Grand Junction-Airport by IHG
A hotel room with two beds, a desk, a chair, and a window with curtains.
A reception desk with a sign for Econoloog by Choice Hotels, a computer, a phone, and a potted plant.
A lobby with a brown leather sofa, a wooden chair, a small table with a lamp, and a staircase.
A kitchen with wooden cabinets, a dishwasher, a coffee machine, and various food items on shelves.

Econo Lodge Grand Junction North

Econo Lodge Grand Junction North
Horizon Drive District
Econo Lodge Grand Junction North
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Our prices for hotels in Mesa are cheapest in September
Price trends for hotels in Mesa
Pricing is based on two traveler single night rates
View properties in September
Typical weather for Mesa
September
High 24°C / low 11°C. Sunny most days.
View properties in September
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Monthly weather averages (˚C)

Top landmarks in Mesa

Powderhorn Resort

8.6/10 (106 reviews)
Skiers and snowboarders might want to test out the slopes at Powderhorn Resort, a skiing spot located 6.7 mi (10.8 km) from central Mesa.
See properties

Learn more about Mesa

Mesa is well-known for its attractions such as Powderhorn Resort and Grand Mesa National Forest.

See all hotels in Mesa
A leafless tree on a rocky hillside with a vast landscape in the background.

Check out reviews of Mesa hotels guests love

La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction

10/10 Excellent
"Great location, free parking and breakfast. Very comfy room and bed."
Stephen 1-night trip
Posted 4 hours ago
La Quinta Inn & Suites by Wyndham Grand Junction
Grand River Hotel

Grand River Hotel

8/10 Good
"It was clean comfortable and quiet."
William 1-night trip
Posted 5 hours ago
Grand River Hotel
Quality Inn Grand Junction near University

Quality Inn Grand Junction near University

8/10 Good
"The breakfast was delicious and the room was very clean and quiet."
Paul 1-night trip
Posted 6 hours ago
Quality Inn Grand Junction near University
Doubletree Hotel Grand Junction

Doubletree Hotel Grand Junction

10/10 Excellent
"The staff was very friendly at check in. I was disappointed in the fact that for the 1st night I reserved a king bed and was given two queens."
Kerry 1-night trip
Posted 3 days ago
Doubletree Hotel Grand Junction
Wagon Wheel Restaurant Bar and Motel

Wagon Wheel Restaurant Bar and Motel

10/10 Excellent
"Quaint motel in Mesa with friendly staff. Restaurant and bar was great!"
Jean 1-night trip
Posted 1 month ago
Wagon Wheel Restaurant Bar and Motel
Powderhorn Lodging

Powderhorn Lodging

10/10 Excellent
"The tiny homes were a perfect place to recconet with family."
Glenda 3-night trip
Posted 2 months ago
Powderhorn Lodging

Frequently asked questions

What accommodations do travelers like in Mesa?
Guests like Wagon Wheel Restaurant Bar and Motel and Powderhorn Lodging.
Can I book a refundable hotel in Mesa?
If you need the flexibility to change your travel plans to Mesa, most properties offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Mesa if I want a vacation home instead of a hotel?
Browse 10 vacation homes on our site. You can also book one of the 18 cabins for your stay.
What will the weather in Mesa be like during my vacation?
July and August are typically the warmest months in Mesa when the average temp is 69°F. January and December are the coldest months when the average temperature is 27°F. March and December are the months with the most rain.
Why should I book my Mesa hotel with Hotels.com?
There are lots of reasons to book your Mesa trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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