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Hotels in South San Francisco

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Dec 9 - Dec 10
Tomorrow
Dec 10 - Dec 11
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

Where to stay in South San Francisco?

Exterior
Hampton Inn San Francisco Airport
Hampton Inn San Francisco Airport
2.5 star property
8.8 out of 10, Excellent, (1005)
The price is $107
$127 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn San Francisco Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out hotels with a pool in South San Francisco

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AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

4.0 star property
Oyster Point
9.2 out of 10, Wonderful, (1003)
The price is $123
$147 total
includes taxes & fees
Dec 21 - Dec 22
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
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You may also like pet-friendly hotels in South San Francisco

Exterior
Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North

3.0 star property
The East Side
8.4 out of 10, Very Good, (1009)
The price is $91
$107 total
includes taxes & fees
Dec 20 - Dec 21
Hilton Garden Inn San Francisco Arpt North
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You can also stay at family-friendly hotels in South San Francisco

Exterior
Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North

3.0 star property
The East Side
8.4 out of 10, Very Good, (1009)
The price is $91
$107 total
includes taxes & fees
Dec 20 - Dec 21
Hilton Garden Inn San Francisco Arpt North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit South San Francisco?

Our prices for hotels in South San Francisco are cheapest in December
Price trends for hotels in South San Francisco
Pricing is based on two traveler single night rates
View properties in December
Currently viewing crowd sizes and weather for December.
Typical weather for South San Francisco
December
Low crowds
High 14°C / low 9°C. Sunny most days.
View properties in December
14°
weather_sun
December, Low crowds, average high temperature 14 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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14°
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January, Low crowds, average high temperature 14 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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15°
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February, Low crowds, average high temperature 15 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
15°
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March, Moderate crowds, average high temperature 15 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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16°
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April, Moderate crowds, average high temperature 16 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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17°
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May, High crowds, average high temperature 17 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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19°
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June, Moderate crowds, average high temperature 19 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
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19°
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July, High crowds, average high temperature 19 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
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August, High crowds, average high temperature 20 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
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20°
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September, High crowds, average high temperature 20 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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19°
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October, Moderate crowds, average high temperature 19 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
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17°
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November, Low crowds, average high temperature 17 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Top neighborhoods in South San Francisco

Oyster Point

South San Francisco's Oyster Point neighborhood offers attractions including San Francisco Bay.

The East Side

South San Francisco's The East Side neighborhood is home to attractions such as San Francisco Bay and San Bruno Point Park.

Top landmarks in South San Francisco

San Bruno Point Park

4.0/5 (181 reviews)
If you like quiet time surrounded by flowers and greenery, hang out at San Bruno Point Park in The East Side. Our travelers also like this walkable area for its restaurants. Want to stretch your legs some more? Head to Bayfront Park and John McLaren Park, both nearby.
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South San Francisco Convention Center

3.9/5 (221 reviews)
South San Francisco Convention Center is worth a visit, located 0.5 mi (0.8 km) from central South San Francisco. Hotels.com travelers also say the area is artsy and has lots of nice beaches. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.
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Learn more about South San Francisco

Look beyond the iconic 'South San Francisco The Industrial City' sign crowning Sign Hill Park for a city with its own distinct identity. Grand Avenue serves up a global feast of family-run eateries where locals debate the merits of each dumpling house. San Bruno Mountain offers hiking trails with sweeping Bay views that explain why residents tolerate the fog. See's Candies factory tours satisfy sweet tooths, while K1 Speed delivers indoor racing thrills. The Convention Center hosts events that draw visitors who are surprised to discover this isn't simply San Francisco's southern neighborhood. Despite tripling in population since World War II, 'South City' maintains its working-class roots while embracing its role as a Peninsula destination in its own right.

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#BVSBlue Aristodes Demetries, One Of Americas Best Known Sculptors Created This Steel Sculpture As A Symbol Of Cabot Cabot And Forbes Industrial Park. Situated 243 Feet Above Sea Level It Rises To A Be Seen From The Bay Bridge, The East Bay and SFO. Called The Wind Harp Locally. It emits eerie sounds when the wind 💨is at its strongest.
Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀
Open Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

Check out reviews of South San Francisco hotels guests love

The Marker Union Square San Francisco

The Marker Union Square San Francisco

10/10 Excellent
"Desk staff was excellent"
john 1-night trip
Posted 1 day ago
The Marker Union Square San Francisco

Frequently asked questions

What accommodations do travelers like in South San Francisco?
Hampton Inn San Francisco Airport, AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront and Home2 Suites by Hilton San Francisco Airport North are all properties that our guests really like.
Can I book refundable accommodations in South San Francisco?
If you need the flexibility to change your travel plans to South San Francisco, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in South San Francisco if I want a vacation rental instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 32 vacation homes. In addition, you can choose from 10 apartments.
What will the weather in South San Francisco be like during my visit?
The warmest months in South San Francisco are usually September and August with an average temp of 62°F. February and January are the chilliest months when the average temp is 53°F. The rainiest months are December and January.
Why should I book my South San Francisco accommodation with Hotels.com?
There are lots of reasons to book your South San Francisco trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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