Hotels in Santa Cruz Island

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Blu Galapagos Sustainable Waterfront Lodge
Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (126 reviews)
  • cleanliness
    Stay on the coast with easy access to Galápagos National Park and free bicycles.
The price is $247
$272 total
Apr 11 - Apr 12
Blu Galapagos Sustainable Waterfront Lodge
Posada del Mar
Posada del Mar
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (225 reviews)
  • cleanliness
    Discover a hotel steps from Galápagos National Park with exceptional staff service.
The price is $70
$70 total
Mar 15 - Mar 16
Posada del Mar
Maidith Galapagos Inn
Maidith Galapagos Inn
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (117 reviews)
  • cleanliness
    Retreat into the Galapagos wild at this Mediterranean hotel near the National Park.
The price is $144
$144 total
Mar 23 - Mar 24
Maidith Galapagos Inn
Enchanted Galapagos Lodge
Enchanted Galapagos Lodge
3.0 star property
Bella Vista
8.0 out of 10, Very Good, (3 reviews)
The price is $224
$224 total
Mar 14 - Mar 15
Enchanted Galapagos Lodge
Semilla Verde Boutique Hotel
Semilla Verde Boutique Hotel
3.5 star property
Bella Vista
9.8 out of 10, Exceptional, (61 reviews)
  • cleanliness
    Relax among wild tortoises at this secluded Galapagos retreat with spa services.
The price is $176
$193 total
Mar 16 - Mar 17
Semilla Verde Boutique Hotel
Hotel Fiesta
Hotel Fiesta
3.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (395 reviews)
  • cleanliness
    Savor tropical island luxury just steps from the Galápagos National Park.
The price is $155
$155 total
Mar 17 - Mar 18
Hotel Fiesta
Angermeyer Waterfront Inn
Angermeyer Waterfront Inn
3.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (130 reviews)
The price is $265
$292 total
Apr 1 - Apr 2
Angermeyer Waterfront Inn
Royal Palm Galapagos, Curio Collection Hotel by Hilton
Royal Palm Galapagos, Curio Collection Hotel by Hilton
4.5 star property
Santa Rosa
9.2 out of 10, Wonderful, (55 reviews)
  • cleanliness
    Galapagos luxury retreat with national park access and pampering spa services.
The price is $262
$289 total
Apr 6 - Apr 7
Royal Palm Galapagos, Curio Collection Hotel by Hilton
Hotel Cucuve
Hotel Cucuve
4.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (281 reviews)
  • cleanliness
    Stay steps from Galápagos National Park at this Puerto Ayora B&B with free breakfast.
The price is $198
$218 total
Mar 16 - Mar 17
Hotel Cucuve
Hotel Ninfa
Hotel Ninfa
3.5 star property
Puerto Ayora
8.4 out of 10, Very Good, (230 reviews)
  • cleanliness
    Unwind near Galápagos National Park with easy access to natural wonders.
The price is $158
$158 total
Mar 14 - Mar 15
Hotel Ninfa
Hotel Palace Galapagos
Hotel Palace Galapagos
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (104 reviews)
  • cleanliness
    Discover the wonders of Puerto Ayora at this hotel near Galápagos National Park.
The price is $81
$81 total
Mar 21 - Mar 22
Hotel Palace Galapagos
La Peregrina Bed & Breakfast
La Peregrina Bed & Breakfast
2.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (33 reviews)
  • cleanliness
    Immerse in Galápagos wilderness at this Puerto Ayora sanctuary near the National Park.
The price is $151
$151 total
Mar 15 - Mar 16
La Peregrina Bed & Breakfast
Galapagos Dreams
Galapagos Dreams
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (130 reviews)
  • cleanliness
    Lush island escape in Puerto Ayora near Galápagos National Park and local piers.
Galapagos Dreams
Capitan Max B&B
Capitan Max B&B
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (216 reviews)
  • cleanliness
    Serene B&B minutes from Galápagos National Park for nature enthusiasts.
The price is $77
$77 total
Mar 21 - Mar 22
Capitan Max B&B
Hotel Galapagos Suites
Hotel Galapagos Suites
2.5 star property
Puerto Ayora
10.0 out of 10, Exceptional, (10 reviews)
  • cleanliness
    Experience the wonders of the Galapagos at this hotel next to the National Park.
The price is $104
$115 total
Mar 16 - Mar 17
Hotel Galapagos Suites
Ikala Galapagos Hotel
Ikala Galapagos Hotel
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (136 reviews)
  • cleanliness
    Boutique retreat with terrace views, minutes from Galápagos National Park.
The price is $221
$243 total
Mar 19 - Mar 20
Ikala Galapagos Hotel
Fernandina Hotel & Spa Galápagos
Fernandina Hotel & Spa Galápagos
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (34 reviews)
  • cleanliness
    Relaxing Galápagos retreat with poolside drinks and spa treatments near the national park.
The price is $113
$113 total
Mar 17 - Mar 18
Fernandina Hotel & Spa Galápagos
Twin Hotel Galapagos
Twin Hotel Galapagos
3.0 star property
Bella Vista
8.4 out of 10, Very Good, (45 reviews)
  • cleanliness
    Unwind at this family-friendly spot with rooftop views of Galápagos National Park.
The price is $92
$92 total
Apr 10 - Apr 11
Twin Hotel Galapagos
Acacia Galapagos Boutique Hotel
Acacia Galapagos Boutique Hotel
2.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (29 reviews)
  • cleanliness
    Galapagos retreat with nature park access and rooftop terrace for sunset viewing.
The price is $243
$243 total
Mar 18 - Mar 19
Acacia Galapagos Boutique Hotel
Hotel La Isla
Hotel La Isla
3.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (67 reviews)
  • cleanliness
    Experience Galápagos right at your doorstep with snorkeling and a scenic rooftop.
The price is $180
$198 total
Mar 14 - Mar 15
Hotel La Isla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top landmarks in Santa Cruz Island

Learn more about Santa Cruz Island

Santa Cruz Island is well-known for its attractions such as Charles Darwin Research Station and Academy Bay. Visitors to this beachside city speak highly of the restaurants whereas sights include Playa de los Alemanes and Tortuga Bay Beach.

Galapagos Marine Iguana walking and swimming on Tortuga bay. Marine iguanas on beach on Santa Cruz Island, Galapagos Islands. Animals, wildlife and amazing nature in Ecuador, South America

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Frequently asked questions

Why should I book my Santa Cruz Island accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz Island trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.