Hotels in Southern Minnesota

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Tonight
May 21 - May 22
Tomorrow
May 22 - May 23
This weekend
May 23 - May 25
Next weekend
May 30 - Jun 1

Where to stay in Southern Minnesota?

AmericInn by Wyndham Mankato Event Center
Free daily continental breakfast

AmericInn by Wyndham Mankato Event Center

2.5 star property
9.2 out of 10, Wonderful, (1002)
The price is $84
$93 total
includes taxes & fees
Jun 8 - Jun 9
AmericInn by Wyndham Mankato Event Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southern Minnesota, MN

Showing deals for:May 30 - Jun 1

Image gallery for Marriott Rochester Mayo Clinic

View from property

Marriott Rochester Mayo Clinic

3.5 star property
Rochester
8.2/10Very Good (501 reviews)
15% off
Price is $389
$169 nightly
$389 total
Total includes taxes and fees
Marriott Rochester Mayo Clinic

Top neighborhoods in Southern Minnesota

Rochester showing skyline and a city

Downtown Rochester

Rochester's Downtown Rochester neighborhood has a host of places to visit such as Mayo Civic Center and Rochester Civic Theater.

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Downtown Rochester

Top landmarks in Southern Minnesota

Winona State University

Winona State University

Enjoy the collegiate vibe when you visit Winona State University, during your trip to Winona. Stroll along the riverfront or experience the area's museums.

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Winona State University

Learn more about Southern Minnesota

Southern Minnesota is applauded for its opera and entertainment with such cultural attractions as Mayo Clinic Health System Event Center and Laura Ingalls Wilder Museum. This family-friendly city has something for everyone including its university life, restaurants, and sights like Mount Kato Ski Area and Blakeslee Stadium.

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Rochester showing skyline and a city
Photo by Howard Lower Photography
Open Photo by Howard Lower Photography

Frequently asked questions

Can I book refundable accommodations in Southern Minnesota?
If you’re looking for the flexibility to change your travel plans to Southern Minnesota, most hotels offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Southern Minnesota if I want a vacation home instead of a hotel?
If you want a good alternative to a hotel, review our selection of 417 vacation homes. In addition, there are 134 apartments and 47 condos.
Why should I book my Southern Minnesota accommodation with Hotels.com?
There are plenty of reasons to book your Southern Minnesota travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.