Hotels in Downtown
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Downtown?
Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-1232.5 star property
Downtown
8.0 out of 10, Very Good, (666)
8.0/10
Very Good
(666)
The price is $74
$74
$87 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area2.5 star property
2 km from Downtown
9.4 out of 10, Exceptional, (205)
9.4/10
Exceptional
(205)
The price is $120
$120
$132 total
includes taxes & fees
Jan 4 - Jan 5, 2026
8.4 out of 10, Very Good, (642)
8.4/10
Very Good
(642)
The price is $89
$89
$98 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area2.5 star property
2.2 km from Downtown
9.2 out of 10, Wonderful, (669)
9.2/10
Wonderful
(669)
The price is $120
$120
$132 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area2.0 star property
3.1 km from Downtown
6.8 out of 10, (722)
6.8/10
(722)
The price is $73
$73
$80 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy2.0 star property
7.5 km from Downtown
9.8 out of 10, Exceptional, (52)
9.8/10
Exceptional
(52)
The price is $76
$76
$127 total
includes taxes & fees
Jan 14 - Jan 15, 2026
9.0 out of 10, Wonderful, (1000)
9.0/10
Wonderful
(1000)
The price is $109
$109
$135 total
includes taxes & fees
Jan 1 - Jan 2, 2026
9.2 out of 10, Wonderful, (800)
9.2/10
Wonderful
(800)
The price is $103
$103
$113 total
includes taxes & fees
Jan 11 - Jan 12, 2026
9.6 out of 10, Exceptional, (558)
9.6/10
Exceptional
(558)
The price is $149
$149
$165 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson4.0 star property
10.6 km from Downtown
9.8 out of 10, Exceptional, (745)
9.8/10
Exceptional
(745)
The price is $179
$179
$199 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn3.0 star property
10.3 km from Downtown
9.6 out of 10, Exceptional, (961)
9.6/10
Exceptional
(961)
The price is $149
$149
$165 total
includes taxes & fees
Jan 1 - Jan 2, 2026
9.8 out of 10, Exceptional, (9)
9.8/10
Exceptional
(9)
The price is $89
$89
$238 total
includes taxes & fees
Jan 1 - Jan 2, 2026
8.0 out of 10, Very Good, (1002)
8.0/10
Very Good
(1002)
The price is $94
$94
$104 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn Clemson-University Area
Hampton Inn Clemson-University Area2.5 star property
9.7 km from Downtown
8.8 out of 10, Excellent, (624)
8.8/10
Excellent
(624)
The price is $110
$110
$122 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center2.5 star property
11.8 km from Downtown
8.2 out of 10, Very Good, (1000)
8.2/10
Very Good
(1000)
The price is $93
$93
$103 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area2.5 star property
11.7 km from Downtown
8.2 out of 10, Very Good, (1000)
8.2/10
Very Good
(1000)
The price is $103
$103
$114 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Holiday Inn Express & Suites Clemson by IHG
Holiday Inn Express & Suites Clemson by IHG2.5 star property
12.4 km from Downtown
8.8 out of 10, Excellent, (950)
8.8/10
Excellent
(950)
The price is $118
$118
$131 total
includes taxes & fees
Jan 10 - Jan 11, 2026
7.6 out of 10, Good, (174)
7.6/10
Good
(174)
The price is $76
$76
$85 total
includes taxes & fees
Jan 29 - Jan 30, 2026
9.0 out of 10, Wonderful, (524)
9.0/10
Wonderful
(524)
The price is $118
$118
$131 total
includes taxes & fees
Jan 6 - Jan 7, 2026
7.0 out of 10, Good, (199)
7.0/10
Good
(199)
The price is $85
$85
$94 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
When is the best time to visit Seneca?
When is the best time to visit Seneca?Our prices for hotels in Seneca are cheapest in January
When is the best time to visit Seneca?
When is the best time to visit Seneca?
Our prices for hotels in Seneca are cheapest in January
Price trends for hotels in Seneca
Pricing is based on two traveler single night rates
Currently viewing crowd sizes and weather for December.
Typical weather for Seneca
December
Low crowds
High 12°C / low 4°C. Sunny most days.
View properties in December 12°
December, Low crowds, average high temperature 12 degrees Celsius, average low temperature 4 degrees Celsius. Sunny most days.
4°
10°
January, Low crowds, average high temperature 10 degrees Celsius, average low temperature 1 degrees Celsius. Partly sunny.
1°
13°
February, Low crowds, average high temperature 13 degrees Celsius, average low temperature 3 degrees Celsius. Partly sunny.
3°
17°
March, Moderate crowds, average high temperature 17 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
6°
22°
April, Moderate crowds, average high temperature 22 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
26°
May, Moderate crowds, average high temperature 26 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
31°
June, Moderate crowds, average high temperature 31 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
19°
32°
July, High crowds, average high temperature 32 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
31°
August, High crowds, average high temperature 31 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
28°
September, High crowds, average high temperature 28 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
18°
23°
October, High crowds, average high temperature 23 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
12°
17°
November, Low crowds, average high temperature 17 degrees Celsius, average low temperature 6 degrees Celsius. Sunny most days.
6°
Monthly weather averages (˚C)
Top landmarks in Downtown
Bertha Lee Strickland Cultural Museum
If museums are on your list of things to see, you might want to browse the collections at Bertha Lee Strickland Cultural Museum in Downtown. If you want to experience more of the culture Seneca has to offer, head to Blue Ridge Field, Keowee Reservoir, and Seneca Historic District.
Check out reviews of Downtown hotels guests love
Hampton Inn & Suites Lavonia
10/10 Excellent
"Awesome"
Hampton Inn & Suites Seneca-Clemson Area
10/10 Excellent
"Check-in was fast and efficient. Our room was clean and spacious. Temperature control was great. Beds were comfy. The breakfast each morning was great, providing sources of protein and fruits as well as the typical continental selections, but they actually had a vat of grits that were just about the right thickness and consistency - just what a Southern boy needs!"
The Inn at Patrick Square
10/10 Excellent
"Front desk staff was amazing and very friendly. Rooms were neat, clean and spacious and had a mini fridge. Will stay again our next visit home. "
Comfort Inn & Suites Clemson - University Area
10/10 Excellent
"The room was immaculate and very comfortable."
Days Inn by Wyndham Anderson
10/10 Excellent
"Love it"
Best Western Plus Clemson Hotel & Conference Center
10/10 Excellent
"The hotel staff were efficient and friendly."
Tru by Hilton Seneca Clemson
10/10 Excellent
"Staff is amazing, hotel and amenities are great. "
Baymont by Wyndham Anderson Clemson
10/10 Excellent
"Everything was great"
Inn @ Clemson
10/10 Excellent
"No frills, comfy clean rooms in an older hotel. "
Find out more about Downtown