Hotels in Sikeston

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Check prices for these dates

Tonight
May 2 - May 3
Tomorrow
May 3 - May 4
Next weekend
May 8 - May 10
In two weeks
May 15 - May 17

Where to stay in Sikeston?

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,004 reviews)
Located minutes from Shawnee National Forest, this hotel offers a refreshing indoor pool and hot tub for unwinding after adventures. Enjoy complimentary breakfast, WiFi, and parking while being close to Cape Splash Family Aquatic Center.
The price is $100
$113 total
includes taxes & fees
May 10 - May 11
Drury Plaza Hotel Cape Girardeau Conference Center
Indoor pool, outdoor pool
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,003 reviews)
Escape to this serene Sikeston hotel with both indoor and outdoor pools near restaurants and shopping. The fitness center, free breakfast, WiFi and parking enhance your stay, while the helpful staff ensures comfort just minutes from Central Park.
The price is $111
$128 total
includes taxes & fees
May 6 - May 7
Drury Inn & Suites Sikeston, MO
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (177 reviews)
Discover Cape Girardeau from this hotel with free WiFi, parking, and continental breakfast. Take a refreshing dip in the indoor pool after exploring nearby attractions like Fort D Historic Site and Cape Splash Family Aquatic Center.
The price is $84
$95 total
includes taxes & fees
May 10 - May 11
Fairfield Inn & Suites by Marriott Cape Girardeau
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,004 reviews)
Discover Cape Girardeau from this central hotel with easy access to restaurants and shopping. Enjoy the indoor pool and fitness center, then wake up to a free breakfast. Helpful staff ensure a smooth stay with convenient free WiFi and parking.
The price is $105
$118 total
includes taxes & fees
May 17 - May 18
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Desk, laptop workspace, blackout drapes, free cribs/infant beds
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
This tranquil hotel provides easy access to Cape Splash Family Aquatic Center and Conservation Nature Center. Enjoy complimentary breakfast, WiFi, and parking, with helpful staff ensuring a relaxing atmosphere near local restaurants and shopping.
The price is $72
$81 total
includes taxes & fees
May 17 - May 18
Pear Tree Inn Cape Girardeau West
Free daily full breakfast
Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,000 reviews)
Experience comfort at this Sikeston hotel, offering free breakfast and parking close to Central Park. The helpful staff welcomes guests to enjoy the indoor pool and fitness center. With easy access to Sikeston Depot Museum, you'll find everything needed for a convenient Missouri stay.
The price is $81
$92 total
includes taxes & fees
May 20 - May 21
Best Western Plus Sikeston I-55
Lobby
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (808 reviews)
Wake up to a free breakfast at this Cape Girardeau hotel, just minutes from Shawnee National Forest and the Mississippi River. Swim in the indoor pool, work out in the fitness center, or relax on the terrace after exploring nearby aquatic attractions.
The price is $106
$119 total
includes taxes & fees
May 10 - May 11
Hampton Inn Cape Girardeau I 55 East
Free daily buffet breakfast
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
Peaceful retreat in Cape Girardeau with shopping and restaurants within walking distance. Start your day with free breakfast before enjoying the indoor pool, then unwind in the hot tub. Near Cape Splash Family Aquatic Center with free WiFi and parking.
The price is $90
$102 total
includes taxes & fees
May 31 - Jun 1
Drury Inn & Suites Cape Girardeau
Lobby sitting area
The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (412 reviews)
The price is $75
$83 total
includes taxes & fees
May 3 - May 4
The Riverstone Hotel Charleston-Sikeston
Lobby sitting area
The Riverview
The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (561 reviews)
Overlooking the Mississippi River, this hotel puts you near Isle Casino Cape Girardeau and Riverfront Park. Enjoy 2 restaurants including Beacon 53, plus free WiFi and complimentary parking during your business-friendly stay.
The price is $132
$149 total
includes taxes & fees
May 4 - May 5
The Riverview
Exterior
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (755 reviews)
The price is $98
$106 total
includes taxes & fees
May 3 - May 4
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,000 reviews)
This peaceful Jackson hotel features a relaxing hot tub and indoor swimming pool. Free breakfast, WiFi, and parking add value, while the helpful staff ensures a comfortable stay. Litz Park and Lazy L Safari Park are nearby attractions to explore.
The price is $80
$85 total
includes taxes & fees
May 25 - May 26
Drury Inn & Suites Jackson MO
Property amenity
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (74 reviews)
Located in Sikeston, this hotel offers free breakfast, WiFi, and parking. Take a refreshing swim in the indoor pool or grab a bite at the restaurant. Nearby attractions include Central Park and Sikeston Depot Museum for local exploration.
The price is $110
$125 total
includes taxes & fees
May 10 - May 11
Fairfield Inn & Suites by Marriott Sikeston
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (462 reviews)
Experience Sikeston from this hotel with free breakfast, WiFi, and parking. Take a morning dip in the indoor pool or hit the fitness center. Near Central Park and Sikeston Depot Museum, guests love the helpful staff and clean rooms.
The price is $105
$119 total
includes taxes & fees
May 30 - May 31
Holiday Inn Express & Suites Sikeston Southwest by IHG
Snack bar
Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (122 reviews)
This Cape Girardeau hotel offers convenient access to Shawnee National Forest and local nature attractions. Start each morning with free breakfast before exploring nearby conservation areas, then return for a swim in the indoor pool or a workout at the fitness center.
The price is $98
$111 total
includes taxes & fees
May 10 - May 11
Tru By Hilton Cape Girardeau
Room, 1 King Bed, Non Smoking | View from room
Eagle Inn Charleston
Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
Active travelers will appreciate the health club at this comfortable Charleston motel. Free WiFi keeps you connected, while complimentary parking saves you money. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.
The price is $549
$609 total
includes taxes & fees
May 3 - May 4
Eagle Inn Charleston
Exterior
Hampton Inn Sikeston
Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (552 reviews)
Dive into vacation mode at this welcoming hotel with an indoor pool and fitness center near Central Park. After enjoying the complimentary breakfast, explore Sikeston Depot Museum before returning to relax in modern rooms with free WiFi.
The price is $102
$115 total
includes taxes & fees
May 17 - May 18
Hampton Inn Sikeston
Lobby
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (504 reviews)
Experience Mississippi River views and explore Shawnee National Forest from this downtown Marriott. The Bistro serves American cuisine while in-room refrigerators and washers/dryers enhance comfort. Enjoy the 24-hour fitness center after visiting nearby Riverfront Park and Isle Casino.
The price is $125
$142 total
includes taxes & fees
May 30 - May 31
Courtyard by Marriott Cape Girardeau Downtown
Lobby
Hampton Inn By Hilton Dexter
Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (22 reviews)
The price is $89
$100 total
includes taxes & fees
May 10 - May 11
Hampton Inn By Hilton Dexter
Property amenity
TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (16 reviews)
The price is $127
$144 total
includes taxes & fees
May 10 - May 11
TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out family-friendly hotels in Sikeston

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
The price is $100
$113 total
includes taxes & fees
May 10 - May 11
Drury Plaza Hotel Cape Girardeau Conference Center
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You can also stay at pet-friendly hotels in Sikeston

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
The price is $100
$113 total
includes taxes & fees
May 10 - May 11
Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

When is the best time to visit Sikeston?

Our prices for hotels in Sikeston are cheapest in December
Price trends for hotels in Sikeston
Pricing is based on two traveler single night rates
View properties in May
Currently viewing crowd sizes and weather for May.
Typical weather for Sikeston
May
High 25°C / low 16°C. Sunny most days.
View properties in May
25°
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May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
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30°
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June, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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32°
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July, no crowd data, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
31°
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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28°
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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21°
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October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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14°
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November, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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9°
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December, no crowd data, average high temperature 9 degrees Celsius, average low temperature 2 degrees Celsius. Partly sunny.
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6°
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January, no crowd data, average high temperature 6 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
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8°
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February, no crowd data, average high temperature 8 degrees Celsius, average low temperature 0 degrees Celsius. Partly sunny.
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14°
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March, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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20°
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April, no crowd data, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
Monthly weather averages (˚C)

Top landmarks in Sikeston

Sikeston Depot Museum

3.8/5 (57 reviews)
The center of Sikeston is home to cultural attractions like Sikeston Depot Museum, so you might want to stop by during your stay. If you want to experience more of the culture Sikeston has to offer, head to Central Park and City of Miner Convention Center.
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Sikeston and related destinations

Catch a hot roll in mid-air at Lambert's Cafe, where servers hurl fresh bread across the dining room with remarkable accuracy. The historic downtown reveals a slice of small-town Americana, while the Sikeston Depot Museum chronicles the railroad heritage that put this place on the map. Central Park offers a leafy respite after exploring Front Street Studio & Art Gallery's local artwork. The City of Miner Convention Center hosts events that draw visitors from across the region. Positioned at the crossroads of major highways, this makes an ideal stopover between larger destinations, though locals insist you'll find reasons to linger beyond the flying carbs that made the town famous.

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Good Day Sunshine Early Morning Sunshine passes through the fog and scatters through the leaves of a tree in Scott County Missouri

Check out reviews of Sikeston hotels guests love

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"I have stayed at many Drury hotels in past years and this was by far the nicest. I love the kick back food and adult beverages served and the wonderful breakfast the next morning. We stayed in a two room suite and it was as gorgeous! Everything was perfectly clean and comfortable. The pool and hot tub were top notch. The area was safe and parking easy. There were multiple restaurants in the area that would suite even the pickiest eater even one on the property. "
Jennifer 1-night trip
Posted 5 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center

Frequently asked questions

What accommodations do travelers recommend in Sikeston?
Guests like Drury Inn & Suites Sikeston, MO, Hampton Inn Sikeston and Best Western Plus Sikeston I-55.
Can I book a refundable accommodation in Sikeston?
If you're looking for the flexibility to change your travel plans to Sikeston, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Sikeston if I want a cheap accommodation?
Hampton Inn Sikeston, Best Western Plus Sikeston I-55 and Days Inn and Suites by Wyndham Sikeston are a few accommodations you might want to consider that'll save you money.
What will the weather in Sikeston be like during my vacation?
The warmest months in Sikeston are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.
Why should I book my Sikeston hotel with Hotels.com?
There are plenty of reasons to book your Sikeston travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.