Hotels in Sikeston

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Tonight
Oct 2 - Oct 3
Tomorrow
Oct 3 - Oct 4
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Where to stay in Sikeston?

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

1. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
$94
$108 total
includes taxes & fees
Oct 12 - Oct 13
Drury Inn & Suites Sikeston, MO
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

2. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
$105
$119 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn Sikeston
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A kitchenette with a coffee machine, a kettle, and storage shelves.
A buffet with various food items, including omelets and baked goods, served in metal containers.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
$99
$113 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Sikeston Southwest by IHG
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

4. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
$101
$114 total
includes taxes & fees
Oct 11 - Oct 12
Fairfield Inn & Suites by Marriott Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
Room

5. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
$85
$97 total
includes taxes & fees
Nov 1 - Nov 2
Best Western Plus Sikeston I-55
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.
A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

6. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
$69
$79 total
includes taxes & fees
Oct 4 - Oct 5
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
Lobby
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.
A spacious lobby with a central atrium, a piano, and a reception desk.

7. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
$66
$76 total
includes taxes & fees
Nov 1 - Nov 2
Days Inn and Suites by Wyndham Sikeston
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A hotel kitchen with a long counter, various appliances, and a tiled backsplash.
A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

8. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
$57
$65 total
includes taxes & fees
Oct 13 - Oct 14
Super 8 by Wyndham Sikeston/Miner Area
Property amenity
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

9. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
$105
$119 total
includes taxes & fees
Oct 18 - Oct 19
TownePlace Suites by Marriott Sikeston
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.
A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.
A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.
A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

10. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
$83
$95 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Inn & Suites Sikeston I-55
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

11. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Oct 6 - Oct 7
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with two beds, a desk, a chair, a TV, and a mirror.
A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.
A bathroom with a bathtub, toilet, and shower curtain.
A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

12. Country Yard Inn and Suite

Country Yard Inn and Suite
Sikeston
$61
$73 total
includes taxes & fees
Oct 3 - Oct 4
Country Yard Inn and Suite
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.
A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

13. The Riverview

The Riverview
Cape Girardeau
$114
$129 total
includes taxes & fees
Oct 5 - Oct 6
The Riverview
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

14. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
$101
$114 total
includes taxes & fees
Oct 8 - Oct 9
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

15. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
$92
$104 total
includes taxes & fees
Oct 11 - Oct 12
Drury Inn & Suites Cape Girardeau
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

16. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$72
$81 total
includes taxes & fees
Oct 11 - Oct 12
Pear Tree Inn Cape Girardeau West
A modern retail area with a display of local items and snacks.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

17. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
$89
$102 total
includes taxes & fees
Oct 8 - Oct 9
Tru By Hilton Cape Girardeau
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

18. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
$106
$119 total
includes taxes & fees
Oct 8 - Oct 9
Hampton Inn Cape Girardeau I 55 East
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

19. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
$101
$115 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A lobby with seating areas, a reception desk, and a bar.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

20. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
$125
$142 total
includes taxes & fees
Oct 12 - Oct 13
Courtyard by Marriott Cape Girardeau Downtown
View all properties

Check out pet-friendly hotels in Sikeston

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
$94
$108 total
includes taxes & fees
Oct 12 - Oct 13
Drury Inn & Suites Sikeston, MO
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
$105
$119 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
Room

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
$85
$97 total
includes taxes & fees
Nov 1 - Nov 2
Best Western Plus Sikeston I-55
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.
A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.
A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.
A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
$83
$95 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Inn & Suites Sikeston I-55
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.
A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
$69
$79 total
includes taxes & fees
Oct 4 - Oct 5
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
Lobby
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.
A spacious lobby with a central atrium, a piano, and a reception desk.

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
$66
$76 total
includes taxes & fees
Nov 1 - Nov 2
Days Inn and Suites by Wyndham Sikeston
Property amenity
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
$105
$119 total
includes taxes & fees
Oct 18 - Oct 19
TownePlace Suites by Marriott Sikeston
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Oct 6 - Oct 7
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A hotel kitchen with a long counter, various appliances, and a tiled backsplash.
A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
$57
$65 total
includes taxes & fees
Oct 13 - Oct 14
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$72
$81 total
includes taxes & fees
Oct 11 - Oct 12
Pear Tree Inn Cape Girardeau West
View all properties

You can also stay at hotels with a pool in Sikeston

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
$94
$108 total
includes taxes & fees
Oct 12 - Oct 13
Drury Inn & Suites Sikeston, MO
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A kitchenette with a coffee machine, a kettle, and storage shelves.
A buffet with various food items, including omelets and baked goods, served in metal containers.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
$99
$113 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Sikeston Southwest by IHG
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
$101
$114 total
includes taxes & fees
Oct 11 - Oct 12
Fairfield Inn & Suites by Marriott Sikeston
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
$105
$119 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
Room

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
$85
$97 total
includes taxes & fees
Nov 1 - Nov 2
Best Western Plus Sikeston I-55
Property amenity
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
$105
$119 total
includes taxes & fees
Oct 18 - Oct 19
TownePlace Suites by Marriott Sikeston
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.
A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.
A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.
A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
$83
$95 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Inn & Suites Sikeston I-55
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Oct 6 - Oct 7
Drury Plaza Hotel Cape Girardeau Conference Center
A modern retail area with a display of local items and snacks.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
$89
$102 total
includes taxes & fees
Oct 8 - Oct 9
Tru By Hilton Cape Girardeau
A modern hotel lobby with a bar area, seating, and artwork on the walls.
A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.
A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.
A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
$98
$110 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn By Hilton Dexter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in Sikeston are cheapest in November
Price trends for hotels in Sikeston
Pricing is based on two traveler single night rates
View properties in October
Typical weather for Sikeston
October
High 21°C / low 11°C. Sunny most days.
View properties in October
21°
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5°
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-1°
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0°
14°
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Monthly weather averages (˚C)

Top landmarks in Sikeston

City of Miner Convention Center

City of Miner Convention Center is worth a visit when in central Miner.
See properties

Sikeston Depot Museum

7.6/10 (57 reviews)
The center of Sikeston is home to cultural attractions like Sikeston Depot Museum, so you might want to stop by during your stay. If you want to experience more of the culture Sikeston has to offer, head to City of Miner Convention Center and Central Park.
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Central Park

7.2/10 (56 reviews)
Central Park is 0.5 mi (0.8 km) from central Sikeston, why not stop by during your stay.
See properties

Sikeston and related destinations

Catch a hot roll in mid-air at Lambert's Cafe, where servers hurl fresh bread across the dining room with remarkable accuracy. The historic downtown reveals a slice of small-town Americana, while the Sikeston Depot Museum chronicles the railroad heritage that put this place on the map. Central Park offers a leafy respite after exploring Front Street Studio & Art Gallery's local artwork. The City of Miner Convention Center hosts events that draw visitors from across the region. Positioned at the crossroads of major highways, this makes an ideal stopover between larger destinations, though locals insist you'll find reasons to linger beyond the flying carbs that made the town famous.

See all hotels in Sikeston
A tree with sunlight filtering through its leaves, creating a warm glow.

Check out reviews of Sikeston hotels guests love

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"EVERYONE was EXTREMELY FRIENDLY"
Rex 1-night trip
Posted 1 day ago
Drury Inn & Suites Sikeston, MO
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

8/10 Good
"Friendly staff. Room was clean and comfortable. Would stay there again!"
Amanda 1-night trip
Posted 1 day ago
Super 8 by Wyndham Sikeston/Miner Area
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent
"Everything"
James 1-night trip
Posted 3 days ago
Holiday Inn Express & Suites Sikeston Southwest by IHG
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent
"trodo estubo excelente gracias por sus servicios"
Julio 1-night trip
Posted 3 days ago
Candlewood Suites Cape Girardeau by IHG
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent
"Clean rooms. Nice breakfast. Very nice staff."
Teresa 1-night trip
Posted 3 days ago
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good
"NA NA NA NA NA NA NA NA NA NA NA NA NA"
Kevin 1-night trip
Posted 4 days ago
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"This was a very good value. It has been the best hotel I've stayed at in awhile."
David 1-night trip
Posted 10 days ago
Days Inn and Suites by Wyndham Sikeston

Frequently asked questions

What accommodations do travelers recommend in Sikeston?
Guests like Drury Inn & Suites Sikeston, MO, Days Inn and Suites by Wyndham Sikeston and Best Western Plus Sikeston I-55.
Can I book a refundable accommodation in Sikeston?
If you're looking for the flexibility to change your travel plans to Sikeston, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Sikeston if I want a cheap accommodation?
Days Inn and Suites by Wyndham Sikeston, Best Western Plus Sikeston I-55 and Super 8 by Wyndham Sikeston/Miner Area are a few accommodations you might want to consider that'll save you money.
What will the weather in Sikeston be like during my vacation?
The warmest months in Sikeston are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.
Why should I book my Sikeston hotel with Hotels.com?
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