Hotels in La Mesa

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Wyndham San Diego Bayside
Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very Good, (6,119 reviews)
Wake to stunning bay views at this waterfront hotel near Port of San Diego. Hop on the trolley at America Plaza Station, just 7 minutes away, or enjoy lunch at Hazelwoods Bayside Deli. The outdoor pool offers a refreshing retreat after exploring nearby Petco Park.
The price is $152
$211 total
includes taxes & fees
Apr 27 - Apr 28
Wyndham San Diego Bayside
InterContinental San Diego by IHG
InterContinental San Diego by IHG
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1,154 reviews)
Experience downtown San Diego from this waterfront hotel with an outdoor pool and rooftop terrace. Just minutes from America Plaza Trolley Station and the Santa Fe Depot, enjoy 2 restaurants and 3 bars while exploring nearby Petco Park.
The price is $251
$358 total
includes taxes & fees
May 25 - May 26
InterContinental San Diego by IHG
The DEXTRO Little Italy, BW Premier Collection
The DEXTRO Little Italy, BW Premier Collection
3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1,440 reviews)
Immerse yourself in San Diego's vibrant Little Italy at this Art Deco hotel. Take a dip in the outdoor pool, enjoy dinner at Ottutto, or grab drinks at the bar. Just 8 minutes from County Center station and a short drive to major attractions.
The price is $95
$110 total
includes taxes & fees
Apr 26 - Apr 27
The DEXTRO Little Italy, BW Premier Collection
Hard Rock Hotel San Diego
Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3,576 reviews)
The price is $212
$294 total
includes taxes & fees
Apr 26 - Apr 27
Hard Rock Hotel San Diego
The Sofia Hotel
The Sofia Hotel
3.5 star property
Downtown San Diego
8.6 out of 10, Excellent, (1,949 reviews)
Unwind in the heart of San Diego at this historic hotel, just minutes from the convention center and Port. A 24-hour fitness center, on-site café, and room service enhance your stay. Within walking distance of USS Midway Museum and convenient transit options.
The price is $129
$174 total
includes taxes & fees
Apr 30 - May 1
The Sofia Hotel
Days Inn by Wyndham San Diego Hotel Circle
Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
Mission Valley
8.0 out of 10, Very Good, (2,653 reviews)
This San Diego hotel offers an outdoor pool and hot tub for relaxation after sightseeing. Located just minutes from San Diego Zoo and Balboa Park with Fashion Valley Transit Center a 13-minute walk away.
The price is $98
$113 total
includes taxes & fees
Apr 28 - Apr 29
Days Inn by Wyndham San Diego Hotel Circle
Hilton San Diego Mission Valley
Hilton San Diego Mission Valley
4.0 star property
Mission Valley
8.2 out of 10, Very Good, (2,406 reviews)
Unwind at this relaxing hotel near Balboa Park and San Diego Zoo. The helpful staff, outdoor pool, and on-site restaurant Polanco create a peaceful retreat. Just a 16-minute walk to Hazard Center Station and minutes from Snapdragon Stadium.
The price is $122
$141 total
includes taxes & fees
May 3 - May 4
Hilton San Diego Mission Valley
Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2,843 reviews)
Coastal elegance awaits at this bayfront retreat just steps from Seaport Village. Enjoy 6 restaurants including Sally's Fish House, 3 bars, and an outdoor pool with stunning sunset views. The San Diego Convention Center and port are minutes away.
The price is $189
$274 total
includes taxes & fees
May 25 - May 26
Manchester Grand Hyatt San Diego
Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2,995 reviews)
Relax at this San Diego spa hotel just minutes from Old Town State Park. After enjoying the outdoor pool and poolside bar, recharge with deep-tissue massages and facials. The fitness center and coffee shop add convenience while nearby attractions await exploration.
The price is $199
$229 total
includes taxes & fees
Apr 26 - Apr 27
Legacy Resort Hotel & Spa
Paradise Point Resort & Spa
Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.8 out of 10, Excellent, (2,544 reviews)
Discover a serene paradise with lush tropical gardens and easy beach access. Rent boats right from the marina, dine at the Californian cuisine restaurant, or unwind with deep-tissue massages at the spa. Mission Bay's treasures and Port of San Diego are just minutes away.
The price is $208
$292 total
includes taxes & fees
Apr 26 - Apr 27
Paradise Point Resort & Spa
Sentral Gaslamp Quarter
Sentral Gaslamp Quarter
4.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (850 reviews)
The price is $144
$196 total
includes taxes & fees
May 10 - May 11
Sentral Gaslamp Quarter
Kings Inn San Diego
Kings Inn San Diego
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (3,684 reviews)
Soak up the sun at this quiet Art Deco hotel with 2 restaurants, including The Waffle Spot serving American cuisine. Located minutes from tourist hotspots, beaches, and Balboa Park, you'll enjoy the beautiful gardens and relaxing atmosphere.
The price is $79
$91 total
includes taxes & fees
Apr 27 - Apr 28
Kings Inn San Diego
Lamplighter Inn & Suites at SDSU
Lamplighter Inn & Suites at SDSU
2.5 star property
Mid-City
9.0 out of 10, Wonderful, (1,408 reviews)
Step into tranquility at this hotel near SDSU, where beautiful gardens create a relaxing retreat. The outdoor pool offers refreshment after exploring nearby Balboa Park and San Diego Zoo. Enjoy free breakfast, WiFi, and parking with restaurants within walking distance.
The price is $169
$191 total
includes taxes & fees
Apr 27 - Apr 28
Lamplighter Inn & Suites at SDSU
Omni San Diego Hotel at the Ballpark
Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,139 reviews)
Immerse yourself in downtown San Diego at this welcoming hotel with an outdoor pool and poolside bar. Located minutes from the Convention Center and near public transit, this hotel offers massage services and a 24-hour fitness center for relaxation between adventures.
The price is $169
$241 total
includes taxes & fees
May 25 - May 26
Omni San Diego Hotel at the Ballpark
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel
3.5 star property
National City
9.2 out of 10, Wonderful, (3,795 reviews)
Unwind in American comfort at this National City hotel, just a short walk from 24th St Trolley Station. The outdoor pool provides cooling respite while Kimball's restaurant serves delicious meals. Free WiFi and convenient parking enhance your San Diego Bay adventure.
The price is $129
$142 total
includes taxes & fees
Apr 26 - Apr 27
Best Western Plus Marina Gateway Hotel
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (706 reviews)
Immerse yourself in this stylish Art Deco hotel in the Gaslamp Quarter. Grab breakfast at 5th & Lox before exploring nearby Petco Park or strolling to the San Diego Convention Center. The cocktail bar offers the perfect nightcap after your urban adventures.
The price is $169
$196 total
includes taxes & fees
May 10 - May 11
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Hilton San Diego Bayfront
Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (2,035 reviews)
Luxurious retreat with an outdoor pool and poolside bar, just steps from Petco Park. Indulge in aromatherapy at the full-service spa, enjoy Californian cuisine at Hudson & Nash, and access the Gaslamp Quarter in 6 minutes.
The price is $163
$238 total
includes taxes & fees
May 25 - May 26
Hilton San Diego Bayfront
Marriott Vacation Club®, San Diego
Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,067 reviews)
The price is $161
$186 total
includes taxes & fees
May 10 - May 11
Marriott Vacation Club®, San Diego
Lafayette Hotel & Club
Lafayette Hotel & Club
4.0 star property
University Heights
9.2 out of 10, Wonderful, (1,613 reviews)
Splash into vacation at the outdoor pool or grab lunch at Quixote, one of 2 restaurants at this San Diego gem. With Balboa Park nearby and free WiFi throughout, you're perfectly placed for both work and play.
The price is $249
$286 total
includes taxes & fees
Apr 27 - Apr 28
Lafayette Hotel & Club
The Horton Grand, Downtown/Gaslamp Quarter
The Horton Grand, Downtown/Gaslamp Quarter
3.5 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,795 reviews)
Immerse yourself in this beautifully preserved historic hotel with comfortable beds and a peaceful courtyard. Just minutes from the Convention Center, Seaport Village, and local cafes. Salt & Whiskey serves American cuisine after a day of nearby sightseeing.
The price is $138
$188 total
includes taxes & fees
Apr 30 - May 1
The Horton Grand, Downtown/Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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When is the best time to visit La Mesa?

Our prices for hotels in La Mesa are cheapest in January
Price trends for hotels in La Mesa
Pricing is based on two traveler single night rates
View properties in April
Currently viewing crowd sizes and weather for April.
Typical weather for La Mesa
April
High 21°C / low 12°C. Sunny most days.
View properties in April
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April, no crowd data, average high temperature 21 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 22 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 25 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
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July, no crowd data, average high temperature 28 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 26 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
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November, no crowd data, average high temperature 22 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
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December, no crowd data, average high temperature 18 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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January, no crowd data, average high temperature 19 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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February, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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March, no crowd data, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Top neighborhoods in La Mesa

Mount Helix

La Mesa's Mount Helix neighborhood offers attractions including Mount Helix Park.

Top landmarks in La Mesa

Learn more about La Mesa

Between the bustle of San Diego and the quiet of the hills, La Mesa lives up to its 'Jewel of the Hills' nickname without trying too hard. The historic Village area offers boutiques and cafés where locals actually eat, not just places that survive on tourist traffic. Mount Helix rewards a short climb with panoramic views that explain why everyone in California seems suspiciously content. Lake Murray Park provides a refreshing escape where fishing lines dangle alongside kayakers who've discovered this urban oasis. Train enthusiasts find unexpected delight at the Pacific Southwest Railway Museum, where vintage locomotives sit frozen in time.

Beautiful sunset with popcorn clouds in San Diego East County with mountain views.

Check out reviews of La Mesa hotels guests love

Frequently asked questions

What accommodations do travelers like in La Mesa?
Can I book a refundable accommodation in La Mesa?
If you need the flexibility to change your travel plans to La Mesa, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in La Mesa if I want a vacation home instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 68 vacation homes. You can also consider one of the 8 apartments or 5 cottages.
What will the weather in La Mesa be like during my trip?
August and September are typically the warmest months in La Mesa when the average temp is 72°F. February and January are the coldest months when the average temperature is 56°F. December and February are the months with the most rain.
Why should I book my La Mesa hotel through Hotels.com?
There are lots of reasons to book your La Mesa trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.