Hotels in La Mesa

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Apr 20 - Apr 21
Tomorrow
Apr 21 - Apr 22
This weekend
Apr 24 - Apr 26
Next weekend
May 1 - May 3

Where to stay in La Mesa?

Lobby
Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San Diego
2.5 star property
La Mesa
8.4 out of 10, Very Good, (1,007 reviews)
Enjoy easy access to Mount Helix Park from this welcoming hotel with an outdoor pool and complimentary breakfast. Near Amaya Trolley Station, you're just a short drive from Balboa Park and San Diego State University, with free parking for stress-free exploring.
The price is $136
$150 total
includes taxes & fees
Apr 27 - Apr 28
Best Western Plus La Mesa San Diego
Blackout drapes, free WiFi, bed sheets
Motel 6 La Mesa, CA - San Diego
Motel 6 La Mesa, CA - San Diego
2.0 star property
La Mesa
7.4 out of 10, Good, (1,006 reviews)
Set in La Mesa, this convenient motel offers free WiFi and parking, plus 24-hour service. Just a 10-minute drive from SDSU and Snapdragon Stadium, with Balboa Park nearby. The 70th St. Trolley Station is an 11-minute walk for easy city exploration.
The price is $96
$106 total
includes taxes & fees
Apr 21 - Apr 22
Motel 6 La Mesa, CA - San Diego
Front of property
Heritage Inn La Mesa
Heritage Inn La Mesa
2.0 star property
La Mesa
7.0 out of 10, Good, (1,406 reviews)
Minutes from Balboa Park and Petco Park, this La Mesa hotel offers an outdoor pool and relaxing hot tub. Enjoy free WiFi and parking, with San Diego State University just a short drive away and La Mesa Boulevard Station within walking distance.
The price is $68
$75 total
includes taxes & fees
Apr 22 - Apr 23
Heritage Inn La Mesa
Blackout drapes, free WiFi, bed sheets
Motel 6 La Mesa, CA
Motel 6 La Mesa, CA
2.0 star property
La Mesa
7.2 out of 10, Good, (1,001 reviews)
This well-placed La Mesa motel offers free WiFi and parking, just a short drive from Balboa Park and San Diego Zoo. Praised for helpful staff and clean rooms, it's minutes from Lemon Grove Depot Station with 24-hour front desk service.
The price is $100
$110 total
includes taxes & fees
Apr 22 - Apr 23
Motel 6 La Mesa, CA
Breakfast and dinner served, American cuisine
Courtyard by Marriott San Diego El Cajon
Courtyard by Marriott San Diego El Cajon
3.0 star property
El Cajon
9.2 out of 10, Wonderful, (1,003 reviews)
Courtyard by Marriott puts you near San Diego State University and Snapdragon Stadium. The American cuisine at The Bistro fuels morning meetings or evening relaxation at the bar. A fitness center and garden round out your stay in this clean, well-staffed hotel.
The price is $152
$167 total
includes taxes & fees
May 10 - May 11
Courtyard by Marriott San Diego El Cajon
Terrace/patio
DoubleTree by Hilton Hotel San Diego - Mission Valley
DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very Good, (1,621 reviews)
Immerse yourself in this tranquil Mission Valley retreat near dining and shopping. Just steps from Hazard Center Station, the hotel offers dual pools, a 24-hour fitness center, and a bar/lounge for unwinding after exploring San Diego Zoo.
The price is $156
$180 total
includes taxes & fees
Apr 26 - Apr 27
DoubleTree by Hilton Hotel San Diego - Mission Valley
Free continental breakfast
La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
Chula Vista
8.6 out of 10, Excellent, (1,595 reviews)
Swim in the outdoor pool or use the fitness center at this Chula Vista hotel near shopping centers. Free breakfast, WiFi and parking add value while Petco Park and San Ysidro Border Crossing are just a short drive away.
The price is $101
$111 total
includes taxes & fees
May 3 - May 4
La Quinta Inn by Wyndham San Diego Chula Vista
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)
Marriott Marquis San Diego Marina
Marriott Marquis San Diego Marina
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,093 reviews)
The price is $239
$324 total
includes taxes & fees
May 1 - May 2
Marriott Marquis San Diego Marina
Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel
3.5 star property
National City
9.2 out of 10, Wonderful, (3,789 reviews)
Unwind in American comfort at this National City hotel, just a short walk from 24th St Trolley Station. The outdoor pool provides cooling respite while Kimball's restaurant serves delicious meals. Free WiFi and convenient parking enhance your San Diego Bay adventure.
The price is $152
$168 total
includes taxes & fees
Apr 26 - Apr 27
Best Western Plus Marina Gateway Hotel
Room, 2 Queen Beds (Trendy, Firepit) | Lobby
Town and Country San Diego
Town and Country San Diego
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1,451 reviews)
Surrounded by beautiful gardens, this San Diego retreat offers 2 outdoor pools and a hot tub for relaxation. Just minutes from Mission Bay and San Diego Zoo, the hotel features American dining options and convenient access to beaches and shopping malls.
The price is $217
$284 total
includes taxes & fees
Apr 29 - Apr 30
Town and Country San Diego
Exterior
Best Western Seven Seas
Best Western Seven Seas
3.0 star property
Mission Valley
7.8 out of 10, Good, (3,403 reviews)
Tropical oasis near Fashion Valley Mall offers peaceful gardens and an outdoor pool with poolside bar. The Seven Seas Cafe serves meals all day, while 2 hot tubs provide relaxation. San Diego Zoo and Balboa Park are just minutes away.
The price is $82
$94 total
includes taxes & fees
Apr 29 - Apr 30
Best Western Seven Seas
Poolside bar
Hard Rock Hotel San Diego
Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3,567 reviews)
The price is $212
$294 total
includes taxes & fees
May 3 - May 4
Hard Rock Hotel San Diego
Restaurant
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1,300 reviews)
Wake to complimentary breakfast at this Victorian hotel, just 4 minutes from Gaslamp Quarter Station. Explore nearby Petco Park and San Diego Convention Center, or squeeze in a workout at the fitness center before strolling to Seaport Village and San Diego Bay.
The price is $152
$176 total
includes taxes & fees
Apr 22 - Apr 23
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Outdoor pool, a heated pool
Days Inn by Wyndham San Diego Hotel Circle
Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
Mission Valley
8.0 out of 10, Very Good, (2,647 reviews)
This San Diego hotel offers an outdoor pool and hot tub for relaxation after sightseeing. Located just minutes from San Diego Zoo and Balboa Park with Fashion Valley Transit Center a 13-minute walk away.
The price is $98
$113 total
includes taxes & fees
Apr 26 - Apr 27
Days Inn by Wyndham San Diego Hotel Circle
Lobby lounge
Courtyard by Marriott San Diego Central
Courtyard by Marriott San Diego Central
3.0 star property
Kearny Mesa
8.8 out of 10, Excellent, (1,002 reviews)
This modern hotel offers an inviting outdoor pool, fitness center, and American cuisine at The Bistro. Just 8 minutes from Montgomery Field airport, you'll enjoy clean rooms and free WiFi while exploring nearby attractions with helpful staff ready to assist.
The price is $122
$140 total
includes taxes & fees
May 10 - May 11
Courtyard by Marriott San Diego Central
View from property
SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
Chula Vista
9.6 out of 10, Exceptional, (629 reviews)
Modern comfort awaits at this Chula Vista hotel with a 24-hour fitness center and relaxing hot tub. Free breakfast, parking, and WiFi enhance your stay near Sky Zone San Diego Indoor Trampoline Park.
The price is $188
$207 total
includes taxes & fees
May 3 - May 4
SpringHill Suites by Marriott Chula Vista Eastlake
Lobby
Embassy Suites by Hilton San Diego Bay Downtown
Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1,731 reviews)
Experience panoramic bay vistas from this downtown San Diego hotel, just steps from USS Midway Museum. Guests love the quiet rooms with refrigerators, complimentary breakfast, and Pacific Fish Company's American cuisine. Seaport Village Station is only 4 minutes away.
The price is $171
$235 total
includes taxes & fees
May 13 - May 14
Embassy Suites by Hilton San Diego Bay Downtown
Lobby
Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2,984 reviews)
Relax at this San Diego spa hotel just minutes from Old Town State Park. After enjoying the outdoor pool and poolside bar, recharge with deep-tissue massages and facials. The fitness center and coffee shop add convenience while nearby attractions await exploration.
The price is $182
$209 total
includes taxes & fees
May 17 - May 18
Legacy Resort Hotel & Spa
Outdoor pool, pool umbrellas, sun loungers
Handlery Hotel
Handlery Hotel
3.5 star property
Mission Valley
8.4 out of 10, Very Good, (2,430 reviews)
Experience a peaceful retreat with an outdoor pool, 2 restaurants, and poolside bar. Just 5 minutes from Mission Bay and steps to Fashion Valley Transit, you'll enjoy quiet surroundings while staying connected to San Diego Zoo and beach adventures.
The price is $116
$133 total
includes taxes & fees
Apr 29 - Apr 30
Handlery Hotel
Dinner served
Omni San Diego Hotel at the Ballpark
Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,159 reviews)
Immerse yourself in downtown San Diego at this welcoming hotel with an outdoor pool and poolside bar. Located minutes from the Convention Center and near public transit, this hotel offers massage services and a 24-hour fitness center for relaxation between adventures.
The price is $229
$310 total
includes taxes & fees
Apr 24 - Apr 25
Omni San Diego Hotel at the Ballpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Get last-minute hotel deals in La Mesa and save more

Sign in to unlock great savings.
Showing deals for:May 1 - May 3
House (4 Bedrooms) | Interior
Spacious Getaway w/ Pool & Spa in La Mesa!

Spacious Getaway w/ Pool & Spa in La Mesa!

Spacious Getaway w/ Pool & Spa in La Mesa!
3.0 star property
La Mesa
The price is $306
per night
$1,112 total
includes taxes & fees
Spacious Getaway w/ Pool & Spa in La Mesa!

When is the best time to visit La Mesa?

Our prices for hotels in La Mesa are cheapest in December
Price trends for hotels in La Mesa
Pricing is based on two traveler single night rates
View properties in April
Currently viewing crowd sizes and weather for April.
Typical weather for La Mesa
April
High 21°C / low 12°C. Sunny most days.
View properties in April
21°
weather_sun
April, no crowd data, average high temperature 21 degrees Celsius, average low temperature 12 degrees Celsius. Sunny most days.
12°
22°
weather_sun
May, no crowd data, average high temperature 22 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
25°
weather_sun
June, no crowd data, average high temperature 25 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
16°
28°
weather_sun
July, no crowd data, average high temperature 28 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
19°
29°
weather_sun
August, no crowd data, average high temperature 29 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
28°
weather_sun
September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
19°
26°
weather_sun
October, no crowd data, average high temperature 26 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
16°
22°
weather_sun
November, no crowd data, average high temperature 22 degrees Celsius, average low temperature 13 degrees Celsius. Sunny most days.
13°
18°
weather_sun
December, no crowd data, average high temperature 18 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
19°
weather_sun
January, no crowd data, average high temperature 19 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
19°
weather_sun
February, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
20°
weather_sun
March, no crowd data, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
Monthly weather averages (˚C)

Top neighborhoods in La Mesa

Cross on Mount Helix, in La Mesa, California.

Mount Helix

La Mesa's Mount Helix neighborhood offers attractions including Mount Helix Park.

Top landmarks in La Mesa

Mount Helix Park

3.7/5 (59 reviews)
If you're planning a bit of sightseeing head to Mount Helix Park— just one of the monuments in Mount Helix. Why not take a stroll along the port and watch the sunset while you're here?
See properties

Computer Museum of America

3.3/5 (36 reviews)
Computer Museum of America is 1 mi (1.6 km) from central La Mesa, why not stop by during your stay. Hotels.com travelers also say the area is walkable and has lots of nice beaches. If you want to experience more of the culture La Mesa has to offer, head to San Diego State University, Cal Coast Credit Union Open Air Theater, and Viejas Arena.
See properties

Learn more about La Mesa

Between the bustle of San Diego and the quiet of the hills, La Mesa lives up to its 'Jewel of the Hills' nickname without trying too hard. The historic Village area offers boutiques and cafés where locals actually eat, not just places that survive on tourist traffic. Mount Helix rewards a short climb with panoramic views that explain why everyone in California seems suspiciously content. Lake Murray Park provides a refreshing escape where fishing lines dangle alongside kayakers who've discovered this urban oasis. Train enthusiasts find unexpected delight at the Pacific Southwest Railway Museum, where vintage locomotives sit frozen in time.

See all hotels in La Mesa
Beautiful sunset with popcorn clouds in San Diego East County with mountain views.

Check out reviews of La Mesa hotels guests love

The Sofia Hotel

The Sofia Hotel

10/10 Excellent
"Excellent stay, but the charge for amenities, I don’t understand. I never used anything but regular items (towels, soap, watched a little TV). Also, parking is a little excessive. "
Ron 3-night trip
Posted 3 hours ago
The Sofia Hotel

Frequently asked questions

What accommodations do travelers like in La Mesa?
Guests like Best Western Seven Seas, Hard Rock Hotel San Diego and Handlery Hotel.
Can I book a refundable accommodation in La Mesa?
If you need the flexibility to change your travel plans to La Mesa, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in La Mesa if I want a vacation home instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 68 vacation homes. In addition, you can choose from 8 apartments.
What will the weather in La Mesa be like during my trip?
August and September are typically the warmest months in La Mesa when the average temp is 72°F. February and January are the coldest months when the average temperature is 56°F. December and February are the months with the most rain.
Why should I book my La Mesa hotel through Hotels.com?
There are lots of reasons to book your La Mesa trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.