Hotels in Santa Cruz

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Check prices for these dates

Tonight
Nov 7 - Nov 8
Tomorrow
Nov 8 - Nov 9
Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22

Where to stay in Santa Cruz?

A modern bar with a long counter, shelves with decorative items, and a coffee machine.

1. Novotel Medellín El Tesoro

Novotel Medellín El Tesoro
4.5 star property
El Poblado
9.4 out of 10, Exceptional, (1,492 reviews)
Unwind at this upscale Medellín sanctuary featuring an outdoor pool, poolside bar, and full-service spa. Just moments from El Tesoro Shopping Park and near Lleras Park, this hotel offers 2 restaurants, free WiFi, and complimentary parking.
The price is $111
$111 total
Dec 5 - Dec 6
Novotel Medellín El Tesoro
A buffet with various fruits, vegetables, and beverages.

2. ibis Medellin

ibis Medellin
3.0 star property
El Poblado
8.8 out of 10, Excellent, (1,000 reviews)
The price is $40
$40 total
Dec 6 - Dec 7
ibis Medellin
A modern bedroom with a large bed, bedside table, and a view of trees through a window.

3. Soy Local Reserva Sajonia

Soy Local Reserva Sajonia
2.5 star property
Rionegro
9.0 out of 10, Wonderful, (112 reviews)
Tranquil hotel near Llanogrande shopping areas offers free WiFi and parking for hassle-free exploration. Just 9 minutes from Jose Maria Cordova Airport with 24-hour front desk service for late arrivals or early departures.
The price is $66
$66 total
Nov 8 - Nov 9
Soy Local Reserva Sajonia
An outdoor patio area with wicker furniture, a brick floor, and a view of a building with large windows and indoor lighting.

4. Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
3.5 star property
Sabaneta
9.4 out of 10, Exceptional, (291 reviews)
Wake up to complimentary breakfast at this Sabaneta hotel, just a 13-minute walk from transit. After exploring nearby Santafé Mall and Oviedo Shopping Center, unwind at the bar or dine at one of 2 restaurants with outdoor terrace views.
The price is $89
$89 total
Dec 4 - Dec 5
Fairfield by Marriott Medellin Sabaneta
A spacious living area with a leather sofa, a coffee table, and a large window with curtains.

5. Hotel Lagoon

Hotel Lagoon
3.5 star property
Rionegro
9.2 out of 10, Wonderful, (399 reviews)
This Rionegro hotel combines outdoor and children's pools with convenient access to Complex Llanogrande Shopping Center. Enjoy free breakfast, WiFi and parking, plus fitness center and bar options after exploring nearby attractions.
The price is $169
$169 total
Nov 9 - Nov 10
Hotel Lagoon
A swimming pool with tiled edges, surrounded by lounge chairs and palm trees.

6. Autenthico Sajonia Hotel Aeropuerto

Autenthico Sajonia Hotel Aeropuerto
2.0 star property
Rionegro
9.0 out of 10, Wonderful, (105 reviews)
Located near Jose Maria Cordova International Airport, this hotel offers convenient access to Silletero Monument and Complex Llanogrande Shopping Center. Enjoy the tranquil garden and terrace after a swim in the outdoor pool, with free WiFi and 24-hour assistance.
The price is $48
$48 total
Nov 9 - Nov 10
Autenthico Sajonia Hotel Aeropuerto
A swimming pool with lounge chairs and umbrellas, surrounded by greenery and a brick building.

7. Hotel Dann Carlton Belfort Medellin

Hotel Dann Carlton Belfort Medellin
4.0 star property
El Poblado
8.8 out of 10, Excellent, (1,004 reviews)
Escape to this spa-focused retreat with soothing massages and an inviting outdoor pool. Just 5 minutes from Poblado and Lleras Parks, enjoy complimentary breakfast, WiFi and parking. The fitness center and poolside bar complement the clean rooms praised by travelers.
The price is $90
$90 total
Nov 15 - Nov 16
Hotel Dann Carlton Belfort Medellin
A modern restaurant with multiple tables and chairs, a counter with staff, and large windows with a view of greenery.

8. Hotel Santiago de Arma

Hotel Santiago de Arma
3.0 star property
Rionegro
9.2 out of 10, Wonderful, (1,003 reviews)
Enjoy Italian cuisine at La Cucina de la Italia restaurant after a busy day. This Rionegro hotel features a welcoming bar, tranquil terrace garden, and convenient perks like free breakfast, WiFi and parking, near Llanogrande Mall.
The price is $103
$103 total
Nov 13 - Nov 14
Hotel Santiago de Arma
A bedroom with a large bed, a chair, and a view through a glass door.

9. Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
3.0 star property
Rionegro
9.4 out of 10, Exceptional, (784 reviews)
Enjoy airport convenience with free 24-hour shuttle service just 2 mi away. Play a round on the golf course, unwind with hot stone massages at the spa, and relax in clean rooms. Explore nearby Llanogrande Shopping Center while enjoying complimentary breakfast and WiFi.
The price is $109
$109 total
Nov 9 - Nov 10
Isak Hotel & Golf Airport
A multi-story building with balconies, a ground-level entrance, and surrounding greenery.

10. Blues Suites Laureles

Blues Suites Laureles
3.0 star property
Laureles
9.2 out of 10, Wonderful, (17 reviews)
The price is $52
$52 total
Nov 8 - Nov 9
Blues Suites Laureles
A modern lounge area with a blue sofa, pendant lights, a refrigerator stocked with snacks, and a chalkboard wall with food illustrations.

11. ibis budget Medellín Itagüí Metro

ibis budget Medellín Itagüí Metro
3.0 star property
Itagüí
9.0 out of 10, Wonderful, (441 reviews)
This Itagüí hotel offers free WiFi and convenient proximity to Santafé Mall and Oviedo Shopping Center. Explore local hiking trails or drive to Poblado Park. Just 3 minutes from Sabaneta Station, guests praise the exceptionally helpful staff.
The price is $50
$50 total
Nov 22 - Nov 23
ibis budget Medellín Itagüí Metro
A hotel room with a balcony overlooking a cityscape, a bed with patterned pillows, and a painting of a flower on the wall.

12. Hotel Dorado La 70

Hotel Dorado La 70
4.0 star property
Laureles
9.0 out of 10, Wonderful, (1,910 reviews)
Embrace the energy near Estadio Station at this Medellín retreat. Just steps from Atanasio Giradot Stadium, you'll enjoy a fitness center, garden terrace, and stylish bar. Free perks include WiFi, breakfast, and parking while the attentive staff ensures a memorable stay.
The price is $70
$70 total
Nov 11 - Nov 12
Hotel Dorado La 70
A hotel sign with a sun emblem, a modern glass building, and flags.

13. La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego
9.0 out of 10, Wonderful, (1,000 reviews)
The price is $84
$84 total
Nov 13 - Nov 14
La Quinta by Wyndham Medellin
A woman in a black swimsuit sitting in a hot tub with a cityscape view through a glass railing.

14. Hotel Living 35 Suites by Growing Group

Hotel Living 35 Suites by Growing Group
4.0 star property
La América
9.6 out of 10, Exceptional, (256 reviews)
Sophisticated accommodations in an excellent location near Botero Plaza and Atanasio Giradot Stadium. Unwind with deep-tissue massages at the onsite spa, grab coffee at the café, or enjoy drinks at the bar. Santa Lucia Station is just a 4-minute drive away.
The price is $46
$46 total
Nov 10 - Nov 11
Hotel Living 35 Suites by Growing Group
A modern indoor pool with a hot tub, lounge chairs, and a view of the surrounding garden.

15. Movich Hotel Las Lomas

Movich Hotel Las Lomas
4.0 star property
Rionegro
9.2 out of 10, Wonderful, (1,001 reviews)
Unwind at this Rionegro retreat near Llanogrande Mall with 2 restaurants and a poolside bar. Take a dip in the outdoor pool, enjoy spa treatments, or work out in the health club. Free WiFi, parking, and airport shuttle add convenience.
The price is $165
$165 total
Nov 28 - Nov 29
Movich Hotel Las Lomas
A modern kitchen with a central island, bar area, and seating.

16. Loma, Medellin, a Tribute Portfolio Hotel

Loma, Medellin, a Tribute Portfolio Hotel
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (468 reviews)
Tucked into vibrant Medellín with an indoor pool for relaxation after exploring. Just minutes from Poblado Park and Lleras Park with free WiFi and parking. El Tesoro Shopping Park and Oviedo Shopping Center are nearby for retail therapy.
The price is $92
$92 total
Nov 27 - Nov 28
Loma, Medellin, a Tribute Portfolio Hotel
A rooftop bar with tables and chairs, a bar counter, and a city view at night.

17. Indie Universe Creative Hotel

Indie Universe Creative Hotel
4.5 star property
Laureles
8.6 out of 10, Excellent, (224 reviews)
Immerse yourself in Medellín's culture at this welcoming hotel near Botero Plaza and Plaza Mayor Convention Center. Enjoy free continental breakfast, WiFi, and receive insider tips from staff praised by past guests. Estadio Station is just a 19-minute walk away.
The price is $48
$48 total
Nov 8 - Nov 9
Indie Universe Creative Hotel
A row of modern, glass-roofed buildings with a garden in front featuring various colorful flowers.

18. NEW STAR CENTER

NEW STAR CENTER
3.0 star property
Rionegro
8.8 out of 10, Excellent, (89 reviews)
Modern comfort awaits at this convenient hotel, just minutes from MDE airport and popular Llanogrande shopping destinations. Enjoy complimentary WiFi while friendly staff provide 24-hour assistance for your daily needs.
The price is $61
$61 total
Nov 8 - Nov 9
NEW STAR CENTER
A rooftop terrace with a hot tub, outdoor seating, and a city view.

19. Hotel Sixtina Plaza Medellin

Hotel Sixtina Plaza Medellin
3.0 star property
Itagüí
8.6 out of 10, Excellent, (176 reviews)
An elegant retreat in Itagüí with a rejuvenating spa offering massages, body treatments, and aromatherapy. Just 5 minutes from Santafé Mall, this hotel features a sauna, steam room, restaurant, and bar. Ayura Station is only a 12-minute walk away.
The price is $35
$35 total
Nov 11 - Nov 12
Hotel Sixtina Plaza Medellin
A hotel room with two beds, a TV, a balcony with a city view, and artwork on the walls.

20. Urbit Social Lofts

Urbit Social Lofts
3.0 star property
Laureles
9.2 out of 10, Wonderful, (576 reviews)
The price is $47
$47 total
Nov 8 - Nov 9
Urbit Social Lofts
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in Santa Cruz

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Check out reviews of Santa Cruz hotels guests love

A woman in a black swimsuit sitting in a hot tub with a cityscape view through a glass railing.
Hotel Living 35 Suites by Growing Group

Hotel Living 35 Suites by Growing Group

Hotel Living 35 Suites by Growing Group
La América

10/10 Exceptional

The hotel was great!! All the staff were so helpful!!! They love to help!! Pretty a good choice and reasonable price
United States
WALTER
Reviewed August 8, 2026
Hotel Living 35 Suites by Growing Group

Frequently Asked Questions

What hotels do travelers like in Santa Cruz?

Guests like Calle Flora Hotel by Jalo, Heiss Hotel By Jalo and Hashtag 98 Hotel By Jalo.

Can I book refundable accommodations in Santa Cruz?

If you need the flexibility to change your plans to Santa Cruz, most hotels offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Santa Cruz be like during my trip?

The warmest months in Santa Cruz are usually August and July with an average temp of 66°F. December and January are the chilliest months when the average temp is 64°F. The rainiest months are May and April.

Why should I book my Santa Cruz accommodation with Hotels.com?

There are plenty of reasons to book your Santa Cruz travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.