2 Star Hotels in Santa Ana

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

5 best 2 Star Hotels in Santa Ana at a glance

Hostal La Cigarra — 2-star hotel in Santa Ana. Guest rating: 7.6/10 — Good.
Hotel República — 2-star hotel in Santa Ana. Guest rating: 6.8/10.
ART CASCO The Hotel — 2-star hotel in Santa Ana. Guest rating: 6.2/10.
Room-sofa Bed Stay Rooftop Pool & Gym, A — 2-star hotel in Santa Ana. Guest rating: 2.0/10.
Hotel Magnolia Boutique — 2-star hotel in San Felipe, 0.7 km from Santa Ana. Guest rating: 8.8/10 — Excellent.

2 Star Hotels in Santa Ana

A restaurant with a long counter, chairs, and tables. There are plants and lights decorating the space.

A hallway with a wooden door marked '14', a window, and a staircase with a railing.

A staircase with white walls and a blue wall at the top. There are green and black safety lines on the stairs.

A living room with wicker furniture, a yellow sofa, and a bookshelf.

Hostal La Cigarra

Santa Ana

$31

$34 total

includes taxes & fees

Sep 1 - Sep 2

A hotel room with a large bed, a window with curtains, a city view, and a lamp.

A corridor with tiled flooring, doors, and a fire extinguisher mounted on the wall.

A plaza with a central open space surrounded by buildings, a crosswalk, and a road with vehicles.

A multi-story building with a flat facade, multiple balconies, and a sign indicating it is a public building.

Hotel República

Santa Ana

$29

$92 total

includes taxes & fees

Sep 1 - Sep 2

A hotel entrance with a green facade and a metal fence.

A spacious living area with a staircase, a dining table, and a television.

A neatly made bed with a teal bedspread, two pillows, and two towels folded at the foot of the bed. There is a wooden nightstand with a phone and a small table beside the bed.

A living room with a television on a stand, a Christmas tree, and a small table with two chairs.

ART CASCO The Hotel

Santa Ana

$25

$27 total

includes taxes & fees

Sep 1 - Sep 2

A high-rise building with a glass balcony overlooking a city skyline and a body of water.

A high-rise building with a grid of windows and balconies.

A modern dining area with grey sofas and blue chairs, large windows offering a view of the sea and cityscape.

Room-sofa Bed Stay Rooftop Pool & Gym, A

Santa Ana

$104

$115 total

includes taxes & fees

Sep 7 - Sep 8

A spacious living room with blue sofas, a marble coffee table, and framed pictures on the walls.

A blue building with arched windows and balconies, labeled 'Magnolia.'

A hotel room with a large bed, a TV, a balcony with a view of the outside, and a window with decorative ironwork.

A bedroom with a large bed, white walls, and a view of a building through arched windows.

Hotel Magnolia Boutique

San Felipe, 0.7 km from Santa Ana

$77

$85 total

includes taxes & fees

Sep 1 - Sep 2

A pool area with lounge chairs, a white building with a crest, and a clear view of the ocean.

A spacious lobby with a modern design, featuring a sofa set, multiple chairs, a coffee table, and a staircase with a glass railing.

A hotel room with a bed, two chairs, a small table with a lamp, a vase with sunflowers, and a view of tall buildings and the sea.

A reception area with a marble counter, a sign for Faranda Express Soho & Casino, and a decorative yellow partition.

Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals

Calidonia, 1.4 km from Santa Ana

$68

$75 total

includes taxes & fees

Sep 6 - Sep 7

A modern hotel lobby with marble walls, a black and white tiled floor, and a kitchen area visible through a glass partition.

A neatly made bed with a grey skirt, a white duvet, and a floral pillow. There are two bedside tables with a phone and a lamp. The room has a simple, clean design with a light-colored floor.

A modern kitchen with a central island, black leather seating, and a view through a window.

A rooftop pool with two people swimming, a blue inflatable float, and a city skyline in the background.

Hotel Dos Mares

Calidonia, 1.3 km from Santa Ana

$43

$48 total

includes taxes & fees

Sep 1 - Sep 2

A modern lobby with a stone wall, two potted plants, and a checkered floor.

w Engaging 2BR in Casco Viejo

San Felipe, 0.6 km from Santa Ana

$95

$142 total

includes taxes & fees

Sep 3 - Sep 4

A room with two beds, a window with curtains, a radiator, and a wardrobe.

A multi-story hotel with a modern design, featuring a prominent entrance and a visible sign indicating it is a hotel.

A reception area with a counter, seating, and a potted plant.

A street view with a sidewalk, a yellow taxi, and storefronts including a neon sign.

Hotel Discovery

Calidonia, 1.6 km from Santa Ana

$27

$30 total

includes taxes & fees

Sep 1 - Sep 2

A bedroom with a large bed, a nightstand, a dresser, and decorative wall art.

A cozy living room with a television, a lamp, and a sofa.

A multi-level interior with a wooden staircase, decorative lighting, and a blue wall.

An outdoor dining area with two stone statues, string lights, and a covered seating area.

ORHO Hotel Boutique 15 Minutes from PTY Airport

20.5 km from Santa Ana

$102

$133 total

includes taxes & fees

Sep 1 - Sep 2

A beachside resort with thatched-roof huts, clear turquoise waters, and palm trees.

A hallway leading to a staircase with a refrigerator and a brown couch in the foreground.

A narrow alleyway with potted plants on one side and a brick wall on the other.

A neatly made bed with white linens and a folded towel, a black headboard, a nightstand, a wall-mounted light, and a window with patterned curtains.

Hotel Pension Corona

Calidonia, 1.8 km from Santa Ana

$19

$21 total

includes taxes & fees

Sep 1 - Sep 2

A room with two beds, a desk with chairs, a television, and a window with blinds.

A bathroom with a sink, toilet, and shower curtain.

A small kitchenette with a microwave, a coffee maker, and a refrigerator. There are two chairs and a sofa.

A kitchen with a wooden cabinet, a TV mounted on the wall, and three bar stools.

B&B Lodgings

26.3 km from Santa Ana

$49

$54 total

includes taxes & fees

Sep 1 - Sep 2

A swimming pool with a tiled edge, surrounded by a fence and potted plants.

A multi-story hotel with a prominent 'HOTEL' sign on the facade.

A hotel room with three beds, a desk, and a chair.

A hotel corridor with hexagonal patterned flooring, a wooden staircase, an elevator, and a reception area with a counter and informational signs.

HOTEL SAN THOMAS INN

Calidonia, 1.5 km from Santa Ana

$30

$33 total

includes taxes & fees

Sep 1 - Sep 2

An outdoor seating area with wooden tables and chairs, surrounded by potted plants and a yellow wall.

A hotel room with two beds, a sofa, and a brick wall with artwork.

A garden pathway with various plants and a yellow brick path.

A group of people seated at a wooden table in a restaurant with a staircase in the background.

Panama House Bed & Breakfast

Bella Vista, 4.6 km from Santa Ana

$29

$32 total

includes taxes & fees

Sep 8 - Sep 9

A hotel room with a bed, a desk, and a chair. There is a window with a view of palm trees and tall buildings.

A staircase with a wooden handrail, surrounded by various plants and sculptures.

A brick pathway leading to a wicker chair surrounded by lush greenery.

A modern building with multiple balconies and a rooftop garden.

Casa Orquídea

Punta Paitilla, 3.8 km from Santa Ana

$57

$63 total

includes taxes & fees

Sep 8 - Sep 9

A view through a window of a building with multiple floors, featuring a mix of residential and commercial buildings, a parking area, and a clear sky.

An elevator with a sign indicating it is a fire emergency exit and a maximum occupancy of two people.

A reception desk with a 'No Entry' sign, a 'No Smoking' sign, and a 'Reception' sign above it.

A hotel room with a bed, a chair, a window with a view of buildings, and an air conditioning unit on the wall.

Pension Monaco

Calidonia, 1.2 km from Santa Ana

$29

$32 total

includes taxes & fees

Sep 1 - Sep 2

Modern apartment in the city center

Bella Vista, 2.8 km from Santa Ana

$71

$108 total

includes taxes & fees

Sep 20 - Sep 21

A living room with a beige sofa, a round glass coffee table, and a wicker side table. A painting of houses is on the wall, and a stone wall is visible.

A staircase with wooden balusters leading to a landing, flanked by stone walls and a polished wooden floor.

A living room with a stone wall, a sofa, a TV, and a ceiling fan.

w Grandiose 1BR w Balcony in San Felipe

San Felipe, 0.8 km from Santa Ana

$94

$143 total

includes taxes & fees

Sep 5 - Sep 6

A bedroom with a bed, a nightstand, a window with curtains, and an air conditioning unit.

A bathroom with a wooden shelf holding a roll of toilet paper and a folded white towel.

A reception area with a check-in counter, a door with a security screen, and a wall-mounted light fixture.

A bathroom with a pedestal sink, toilet, and shower.

Hotel Residencial Turistico Cuba

Calidonia, 1.9 km from Santa Ana

$24

$27 total

includes taxes & fees

Sep 1 - Sep 2

See more properties

Top landmarks in Santa Ana

El Machetazo Santa Ana

If you want to give your credit card some exercise, head out to El Machetazo Santa Ana in Santa Ana. Splash some more cash at Avenida Central and Paseo de Las Bovedas.

See properties

Check out reviews of Santa Ana hotels guests love

Ramada Plaza by Wyndham Panama Punta Pacifica

8/10 Good

"The breakfast was cool, parking clean"

Hotel Riu Plaza Panama

10/10 Excellent

"I love my experience there at RIU Panama, and the staff was helpful,the rooms was always clean and neat.Will visit again."

Waymore Hotel Spa & Casino

10/10 Excellent

"Great property"

JW Marriott Panama

10/10 Excellent

"Room was very clean and comfortable."

Central Hotel Panama Casco Viejo

8/10 Good

"Muy bueno el desayuno"

The Executive Hotel

10/10 Excellent

"Excellent hotel and staff; definitely will repeat"

Aloft by Marriott Panama

10/10 Excellent

"It was a great stay"

Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals

8/10 Good

"Breakfast was very good."

Casco View Apartments

10/10 Excellent

"The apartment was beautifully decorated, modern, and clean. The staff are friendly, extremely resourceful, and caring. They went above and beyond to ensure my deliveries, including prescriptions and food, were received. The staff also referred me to a wonderful Logistics Manager who drove and accompanied me to all of my appointments. A top-tier experience. Best customer service I've experienced in years!"