Luxury Hotels in Panama City
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Luxury Hotels in Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
9.6 out of 10, Exceptional, (621)
The price is $206
$226 total
includes taxes & fees
Nov 23 - Nov 24
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top neighborhoods in Panama City
Casco Viejo
Panama City's Casco Viejo neighborhood is known for its bars and offers a host of things to see such as Interoceanic Canal Museum and National Theater.
Bella Vista
Panama City's Bella Vista neighborhood is known for its cafes and restaurants, and entices visitors with attractions including Via Espana and Iglesia del Carmen.
El Cangrejo
Panama City's El Cangrejo neighborhood is known for its restaurants and cafes, and entices visitors with attractions including Crown Casino and Luxor Towers.
San Francisco
Panama City's San Francisco neighborhood is known for its restaurants and offers a host of things to see such as ATLAPA Conventions Center and Multiplaza Pacific Mall.
San Felipe
Panama City's San Felipe neighborhood has a host of places to visit such as Interoceanic Canal Museum and National Theater.
Top landmarks in Panama City
Multiplaza Pacific Mall
Multiplaza Pacific Mall
4.5/5(634 reviews)
If you want to give your credit card some exercise, head out to Multiplaza Pacific Mall in San Francisco. Splash some more cash at Avenida Balboa, Pacific Center, and Soho City Center.
Cinta Costera
Cinta Costera
4.5/5(456 reviews)
If you like quiet time surrounded by flowers and greenery, hang out at Cinta Costera in Calidonia. Want to stretch your legs some more? Head to Ancon Hill and Metropolitan Nature Park, both nearby.
Keep exploring
- Top areas for Luxury Hotels
- Theme
- Neighborhoods
- Landmarks
- Star Rating
- Accommodation Types
- Top cities in Panama
- Hotels close to nearby airports
- More Hotels
- Most popular destinations
- Panama City Cheap Hotels
- Panama City Hotels with Free Breakfast
- Panama City Casino Hotels
- Panama City Hotels with a Pool
- Panama City Pet-Friendly Hotels
- Panama City Resorts and Hotels with Spas
- Panama City Family Hotels
- Panama City Hotels with Kitchens
- Panama City Hotels with Parking
- Panama City Hotels with a Gym
- Panama City Business Hotels
- Panama City Beach Hotels
- Casco Viejo Hotels
- El Cangrejo Hotels
- Costa del Este Hotels
- Bella Vista Hotels
- Punta Paitilla Hotels
- Punta Pacifica Hotels
- Calidonia Hotels
- San Francisco Hotels
- Rio Abajo Hotels
- Bethania Hotels
- Marbella Hotels
- Parque Lefevre Hotels
- Juan Diaz Hotels
- San Felipe Hotels
- Obarrio Hotels
- Santa Ana Hotels
- Campo Alegre Hotels
- Amador Hotels
- El Chorrillo Hotels
- Balboa Hotels
- Hotels near Albrook Shopping Mall
- Hotels near Multiplaza Pacific Mall
- Hotels near Calle 50
- Hotels near El Dorado Mall
- Hotels near Via Espana
- Hotels near Cinta Costera
- Hotels near Los Pueblos Commercial Center
- Hotels near Panama Viejo
- Hotels near Metropolitan Cathedral of Panama
- Hotels near Amador Convention Center
- Hotels near Panama Canal Railway
- Hotels near Fuerte Amador Resort & Marina
- Hotels near Miraflores Locks
- Hotels near Amador Causeway
- Hotels near Iglesia del Carmen
- Hotels near Avenida Balboa
- Hotels near Uruguay Street
- Hotels near ATLAPA Conventions Center
- Hotels near Estadio Rommel Fernandez
- Hotels near Estadio Nacional Rod Carew
- Hotels in Bocas del Toro
- Hotels in Rio Hato
- Hotels in Boquete
- Hotels in Colon
- Hotels in Veracruz
- Hotels in El Valle de Anton
- Hotels in Bastimentos
- Hotels in Tocumen
- Hotels in San Blas Islands
- Hotels in David
- Hotels in Playa Coronado
- Hotels in Isla Frangipani
- Hotels in David Sur
- Hotels in Nueva Gorgona
- Hotels in El Chiru
- Hotels in Punta Chame
- Hotels in Ancon
- Hotels in San Carlos
- Hotels in Taboga
- Hotels in Santa Catalina
- Hotel Ojos del Rio
- Bristol Panama, a Registry Collection Hotel
- TRYP by Wyndham Panamá Centro
- Aloft Panama
- Renaissance Panama City Hotel
- Residence Inn by Marriott Panama City
- Hyatt Regency Panama City
- Sofitel Legend Casco Viejo, Panama City
- Hilton Panama
- The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
- MARINN Tropical Vibes Hotel
- Courtyard by Marriott Panama Multiplaza Mall
- Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
- American Trade Hotel
- Radisson Hotel Panama Canal
- Hospedium Princess Hotel Panama
- Hotel San Felipe
- Marriott Executive Apartments Panama City, Finisterre
- InterContinental Miramar Panama by IHG
- Hotel Coral Suites
- Holiday Inn Panama Distrito Financiero by IHG
- Hotel El Panama by Faranda Grand, a member of Radisson Individuals
- The Westin Panama
- Ramada Panama Centro Via Argentina
- Hotel La Compañía Casco Antiguo
- Torres de Alba Hotel & Suites
- Boutique Apartments Panama
- Canova
- Best Western El Dorado Panama Hotel
- Summit Rainforest & Golf Resort
- Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals
- Hilton Garden Inn Panama City Downtown, Panama
- Hampton by Hilton Panama
- Le Meridien Panama
- Victoria Hotel and Suites Panama
- Hotel Casa Panamá
- Panama House Bed & Breakfast
- Hotel Mio Panama
- Crowne Plaza Panama by IHG
- Casco View Apartments
- Magnolia Inn
- Hotel Lisboa
- Exe Oriental Panama
- Hotel Costa Inn
- Hotel Tower House Suites
- Hotel Terranova
- Nomada Container Hotel Panama City
- Best Western Plus Panama Zen Hotel
- Hotel Milan
- Euro Hotel
Hotels
- Hotel del Rio
- Hotel Intercity Zapopan
- Barceló Huatulco - All Inclusive
- Los Jitos Hotel & Suites
- Hotels near U.S. Embassy
- Hotels in May Pen
- Hotel Azul Ixtapa Grand Resort Spa and Convention Center
- The Nolitan
- Bristol Hotel
- DoubleTree by Hilton Guadalajara Centro Historico
- Villa Mercedes Merida, Curio Collection by Hilton
- Hotel Misión Express San Juan Del Río
- Barceló Guadalajara
- Hotels near Coachella Music Festival
- Hotels in Colon
- Hotels near Eiffel Tower
- Hotel Rio Malecon
- Hotels near Albrook Shopping Mall
- R INN de TJ
- Hotels in Brisas de Zicatela
- Hotels near Multiplaza Pacific Mall
- Hotels in South Lake Tahoe
- ibis Monterrey Aeropuerto
- Palafitos Overwater Bungalows, Catamarán, Cenote, All & More Inclusive - Adults Only
- Ambiance Suites Cancun
- San Felipe Beach Hotel
- Hotel Eiffel