Hotels in Charleston
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Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (620 reviews)
cleanliness Gateway to historic Charleston with easy interstate access and free breakfast.

Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (105 reviews)
cleanliness Stay fit while visiting Charleston with a health club at this convenient motel.

Pear Tree Inn Sikeston
Pear Tree Inn SikestonSikeston
9.4 out of 10, Exceptional, (1,003 reviews)
cleanliness Quiet, dual pool paradise near Central Park in charming Sikeston.

Best Western Plus Sikeston
Best Western Plus SikestonSikeston
8.4 out of 10, Very Good, (1,011 reviews)
cleanliness Stay minutes from Central Park at this inviting hotel with an indoor pool and gym.

Country Yard Inn and Suite
Country Yard Inn and SuiteSikeston
6.8 out of 10, (121 reviews)
cleanliness Enjoy a comfortable base in Sikeston with free perks and 24-hour service.

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,002 reviews)
cleanliness Peaceful highway-adjacent retreat with indoor and outdoor pool options.

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very Good, (730 reviews)
cleanliness Enjoy a serene stay in Sikeston, just minutes from Central Park and Depot Museum.

Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
6.8 out of 10, (580 reviews)
cleanliness Convenient Sikeston escape with free amenities and easy access to local attractions.

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,001 reviews)
cleanliness Enjoy a peaceful night's rest and complimentary breakfast at this quiet Sikeston hotel.

Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
8.4 out of 10, Very Good, (284 reviews)
cleanliness Cozy stay near Central Park with indoor pool, free WiFi, and friendly staff.

Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (275 reviews)
cleanliness Convenient Cairo hotel offers comfortable stay with free breakfast and WiFi.

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (446 reviews)
cleanliness Convenient stay near Central Park with refreshing pool and complimentary perks.

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (463 reviews)
cleanliness Discover contemporary comfort with an indoor pool just off I-55 in Sikeston.

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (49 reviews)
cleanliness Discover a modern retreat with a welcoming indoor pool and sip drinks at the bar.

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (11 reviews)

La Center Motel
La Center MotelLa Center
7.8 out of 10, Good, (17 reviews)
cleanliness Only minutes from the Ohio River Valley, this hotel offers free perks in La Center.

Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
8.2 out of 10, Very Good, (890 reviews)

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (479 reviews)
cleanliness Riverside location with Marriott quality and nearby national forest access.

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (490 reviews)
cleanliness Try your luck at the casino and savor American cuisine at this Cape Girardeau hotel.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Charleston
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Learn more about Charleston
Charleston is well-known for its attractions such as Mississippi River and Ohio River. Visitors give high marks to the city's restaurants and small-town setting.

Check out reviews of Charleston hotels guests love

Pear Tree Inn Sikeston
10/10 Excellent





































































