Hotels in Charleston

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Tonight
Oct 17 - Oct 18
Tomorrow
Oct 18 - Oct 19
Next weekend
Oct 23 - Oct 25
In two weeks
Oct 30 - Nov 1

Where to stay in Charleston?

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
A reception area with a counter, a flat-screen TV, and a window with blinds.
A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.
A hotel with a covered entrance, a sign for the brand, and a parking lot with cars.

1. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
$60
$67 total
includes taxes & fees
Oct 18 - Oct 19
Super 8 by Wyndham Charleston/Sikeston East MO
A building with a fountain and flower beds in front.
A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.
A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.
A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

2. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
$66
$74 total
includes taxes & fees
Oct 19 - Oct 20
The Riverstone Hotel Charleston-Sikeston
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
A kitchen with wooden cabinets, a granite countertop, a built-in microwave, and a window with a view.
A motel with a sign reading "Eagle Inn" and a parking lot with several cars.
A bathroom with a sink, mirror, towel rack, shower, and toilet.

3. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
$66
$74 total
includes taxes & fees
Oct 18 - Oct 19
Eagle Inn Charleston
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

4. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
$94
$108 total
includes taxes & fees
Oct 25 - Oct 26
Drury Inn & Suites Sikeston, MO
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A Travel Inn and Suites with a brick facade, a flat roof, and a welcoming entrance.
A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

5. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
$69
$79 total
includes taxes & fees
Oct 18 - Oct 19
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.
Room

6. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
$80
$91 total
includes taxes & fees
Nov 8 - Nov 9
Best Western Plus Sikeston I-55
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
Lobby
A spacious lobby with a central atrium, a piano, and a reception desk.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

7. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
$66
$76 total
includes taxes & fees
Nov 1 - Nov 2
Days Inn and Suites by Wyndham Sikeston
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

8. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
$101
$115 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield Inn & Suites by Marriott Sikeston
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.
A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.
A motel with a covered entrance, multiple rooms, and a parking lot.

9. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
$57
$65 total
includes taxes & fees
Oct 25 - Oct 26
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with two beds, a desk, a chair, a TV, and a mirror.
A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.
A bathroom with a bathtub, toilet, and shower curtain.
A reception area with a counter, a coffee machine, and seating.

10. Country Yard Inn and Suite

Country Yard Inn and Suite
Sikeston
$58
$70 total
includes taxes & fees
Oct 18 - Oct 19
Country Yard Inn and Suite
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

11. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
$105
$120 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn Sikeston
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A kitchenette with a coffee machine, a kettle, and storage shelves.
A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

12. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
$95
$108 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express & Suites Sikeston Southwest by IHG
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.
A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.
A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.
A living room with two sofas, a coffee table, a TV, and a cabinet.

13. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
Sikeston
$79
$90 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn & Suites Sikeston I-55
A hotel lobby with a reception desk, seating area, and a large window.
A hotel room with a desk, chair, television, and a lamp.
A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.
A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

14. Quality Inn Cairo I-57

Quality Inn Cairo I-57
Cairo
$68
$76 total
includes taxes & fees
Nov 13 - Nov 14
Quality Inn Cairo I-57
Property amenity
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

15. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
$109
$124 total
includes taxes & fees
Oct 25 - Oct 26
TownePlace Suites by Marriott Sikeston
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

16. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
$90
$102 total
includes taxes & fees
Oct 25 - Oct 26
Drury Inn & Suites Cape Girardeau
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

17. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$72
$81 total
includes taxes & fees
Oct 25 - Oct 26
Pear Tree Inn Cape Girardeau West
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

18. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Oct 22 - Oct 23
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

19. The Riverview

The Riverview
Cape Girardeau
$114
$129 total
includes taxes & fees
Oct 19 - Oct 20
The Riverview
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.
A bathroom with yellow walls, a wooden cabinet, a sink, a mirror, and a hanging towel rack.
A compact room with a television on a cabinet, a microwave, a small refrigerator, a table, and a chair.
A motel with a red roof and beige walls, a parking lot, and a signboard.

20. La Center Motel

La Center Motel
La Center
$54
$63 total
includes taxes & fees
Oct 18 - Oct 19
La Center Motel
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Our prices for hotels in Charleston are cheapest in January
Price trends for hotels in Charleston
Pricing is based on two traveler single night rates
View properties in October
Typical weather for Charleston
October
High 21°C / low 11°C. Sunny most days.
View properties in October
21°
11°
14°
5°
9°
2°
6°
-1°
8°
0°
14°
5°
20°
10°
25°
15°
30°
20°
31°
22°
31°
21°
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17°
Monthly weather averages (˚C)

Learn more about Charleston

Charleston is well-known for its attractions such as Mississippi River and Ohio River. Visitors give high marks to the city's restaurants and small-town setting.

See all hotels in Charleston
A sunset over a calm lake with tall trees reflected in the water.

Check out reviews of Charleston hotels guests love

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Great as usual"
Frank 1-night trip
Posted 19 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent
"I was surprised how reasonable the cost was considering how clean & nice all of the finishers were."
John 1-night trip
Posted 19 hours ago
Courtyard by Marriott Cape Girardeau Downtown
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"We arrived just before the evening meal was closing so the staff recommended we get something to eat and then check in. Very thoughtful!"
Caroline 1-night trip
Posted 1 day ago
Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"It was nice having a 2 room suite. Plenty of room. Fridge with freezer was a plus."
Randy 1-night trip
Posted 2 days ago
Days Inn and Suites by Wyndham Sikeston
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

8/10 Good
"It was good. No complaints. The walls weren't terrible. No smells. It was clean & nice."
John 1-night trip
Posted 2 days ago
Hampton Inn Cape Girardeau I 55 East
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"We have stayed at the Pear Tree several times and never disappointed!! Great staff, clean rooms, generous breakfast. A special thanks to Lydia who took extra care to make our last stay remarkable. Thank you."
Sally 1-night trip
Posted 2 days ago
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"The room was clean, the pillows were great and the bed was comfy. the dinner service and breakfast were very nice and the staff was helpful and friendly! 10/10"
Cynthia 1-night trip
Posted 2 days ago
Drury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"We have stayed here a number of times over 20 years. It’s always clean and well maintained. Breakfast is very good. Staff is always friendly and helpful."
John 3-night trip
Posted 4 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"good, clean, affordable :)"
Nicholas 1-night trip
Posted 4 days ago
Super 8 by Wyndham Sikeston/Miner Area

Frequently asked questions

What hotels do travelers recommend in Charleston?
Guests like Super 8 by Wyndham Charleston/Sikeston East MO, The Riverstone Hotel Charleston-Sikeston and Eagle Inn Charleston.
Can I book a refundable accommodation in Charleston?
If you're looking for the flexibility to change your plans to Charleston, most accommodations offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where should I consider staying in Charleston if I'm looking for a cheap accommodation?
An inexpensive option worth considering is The Riverstone Hotel Charleston-Sikeston.
What will the weather in Charleston be like during my vacation?
July and August are typically the warmest months in Charleston when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. April and March are the months with the most rain.
Why should I book my Charleston accommodation with Hotels.com?
There are lots of reasons to book your Charleston trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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