Hotels in Mosopuquio

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Where to stay in Mosopuquio?

A lakeside building with a reflection in the water, surrounded by trees.

A spacious bedroom with a large bed, a wooden ceiling, and a view of the city through a large window.

A brick pathway with a wooden railing, surrounded by greenery and trees.

A resort with a swimming pool, lounge chairs, and a gazebo.

1. Hotel El Lago by Luoxo

Sabandía

$62

$69 total

Nov 3 - Nov 4

An indoor dining area with wicker chairs and tables, wooden ceiling beams, and a view of the cityscape through large windows.

A reception area with a stone counter, two vases with flowers, framed artwork on the wall, and a large text display.

A modern building with a prominent glass facade and a unique triangular design.

A spa area with a hot tub, a marble table with a vase of flowers, and a view of the city through large windows.

2. Sonesta Hotel Arequipa

Cerro Colorado District

$105

$116 total

Oct 11 - Oct 12

A restaurant with a tiled backsplash, wooden chairs, and a counter with a mirror and plants.

A hotel room with a wooden headboard, a bed with white and blue bedding, a bedside table with a lamp, a chair, and a large window with curtains.

A reception desk with a wooden finish and a sign that reads "Lirium HOSTAL".

A living room with a brown leather sofa, two blue armchairs, a round coffee table, and three wall-mounted mirrors.

3. Hostal Lirium

Sachaca

$27

$27 total

Nov 3 - Nov 4

A hotel lobby with a reception desk, a seating area with patterned chairs, a glass coffee table, and a chandelier.

A hotel room with two beds, a wooden headboard, a nightstand, and a window with curtains.

A modern living room with a beige sectional sofa, a glass coffee table, and two potted plants.

A kitchen counter with breakfast items, including sliced ham, bread, and condiments.

4. HOTEL ALTIVA

Cayma

$32

$32 total

Oct 6 - Oct 7

A breakfast buffet with various fruits, beverages, and a sign indicating self-service.

A breakfast table with various food items and drinks, a rose, and a view of a cityscape with buildings and a mosque.

A hotel lobby with a reception desk, a seating area, and a refrigerator.

5. Hotel TerraMistica Monasterio

José Luis Bustamante y Rivero

$41

$41 total

Oct 6 - Oct 7

A covered patio area with a glass table and chairs, surrounded by arches and potted plants.

A bedroom with a wooden floor, a bed with a headboard, a nightstand, a window with curtains, and a brown leather chair.

A dining area with a table set for a meal, a chandelier, and a window with decorative iron bars.

A well-maintained garden with a variety of trees, a lawn, and a white metal fence.

6. Hotel Casa Campo by Cassana

Cayma

$44

$44 total

Oct 10 - Oct 11

A bathtub with rose petals and champagne glasses.

A modern hotel with a flat roof, large windows, and a sign indicating it is a hotel.

A neatly made bed with a tray of food and drinks, a vase with flowers, and a mirror on the wall.

A modern indoor garden with artificial grass, potted plants, and decorative wall art.

7. Hotel La Cuesta de Cayma

Cayma

$68

$72 total

Oct 6 - Oct 7

A well-maintained garden with various potted plants and flowers, a large decorative pot, and a stone pathway.

A reception desk with a floral arrangement, framed artwork, and a painting on the wall.

A rooftop terrace with outdoor seating, including wicker chairs and white lounge chairs, and a small table with a vase of flowers.

A hotel entrance with a tiled floor, a staircase leading to the upper floor, and potted plants along the walls.

8. HOTEL AREQUIPA INN

Historical Center

$37

$37 total

Nov 5 - Nov 6

A hotel room with a bed, a desk, a chair, a coat rack, a window with curtains, and a wall-mounted TV.

A restaurant with a bar area, tables with chairs, and a kitchen in the background.

A multi-story building with a sign that reads 'HOSTAL ORI.'

A building with a sign reading 'HOSTAL QORI' and a two-story structure with a tiled roof.

9. Qori Arequipa

Cerro Colorado District

$45

$45 total

Oct 6 - Oct 7

A bar area with wooden stools, a wooden wall with bottles, and a large window.

A room with a view of snow-capped mountains through a large window, a ceiling with a dotted pattern, and hanging light fixtures.

A modern building with large windows, indoor plants, and a well-maintained garden.

A multi-level interior with glass railings, an elevator, and a staircase with a decorative art piece.

10. Mint Hotel

Historical Center

$51

$55 total

Oct 6 - Oct 7

A hotel room with a bed, bedside table, lamp, and a small table with a vase of sunflowers.

A hallway with a wall displaying various decorative items and a website address.

A chef preparing food at a wooden table with a rustic wall in the background.

A wicker sofa with cushions, a small table with a teapot and candles, and a view of two lit towers against a mountain backdrop.

11. Los Tambos - Boutique

Historical Center

$62

$68 total

Nov 2 - Nov 3

A pool area with a stone ceiling, a chandelier, and potted plants.

An arched entrance with a brick ceiling, potted plants, and a pathway leading to a building.

A courtyard with potted plants, a fountain, and a building with yellow walls and arches.

An indoor dining area with brick flooring, wooden tables, chairs, and a mural on the wall.

12. La Hostería

Historical Center

$111

$111 total

Oct 31 - Nov 1

A stone arched window with a cushioned bench and two pillows, overlooking a garden with plants and a door.

A cozy, stone-walled interior with a dining area featuring yellow chairs and a marble table, and a kitchen with modern appliances.

An interior corridor with a rustic stone wall, a wooden door, and a welcome sign.

13. Hampton by Hilton Arequipa

Historical Center

$103

$113 total

Oct 18 - Oct 19

A bedroom with a four-poster bed, a bedside table, a bench, a nightstand, and a mirror.

A hallway with a wooden door, a lamp, a sofa, and a stone wall.

A dining area with tables set for service, a chandelier, and a mirror on the wall.

A bar area with a counter, stools, and a television screen.

14. Casa Andina Premium Arequipa

Historical Center

$158

$173 total

Oct 12 - Oct 13

A buffet with a variety of food items and beverages, including fruits, pastries, and a red refrigerator in the background.

A hotel room with a large bed, a desk, a chair, and a wall mural of a historical building.

A glass-enclosed patio with a table and chairs, surrounded by potted plants and a view of trees and buildings.

An elevator with glass doors, a wooden floor, and a view of trees outside.

15. Dreams Boutique Hotel

Historical Center

$57

$63 total

Oct 6 - Oct 7

A breakfast table with a variety of dishes, a vase with flowers, and a potted plant by a window with columns.

A table with breakfast items, a vase with flowers, and a mountain view in the background.

A grand staircase with a wooden handrail and a curved design, leading to an upper floor.

A hallway with a red wall, a large mirror, a bench, a chandelier, and a vase with flowers.

16. Casa Arequipa

Historical Center

$62

$62 total

Oct 7 - Oct 8

A modern building with glass facades and a reflective pool.

A modern hotel room with a large bed, bedside lamps, a bathroom with a bathtub, and a shower.

A balcony with a table featuring a bottle and two glasses, overlooking a historic building with two towers and a mountain backdrop.

A large bathtub with a wooden bench, a towel rack, and a small plant.

17. ARIQUEPAY HOTEL

Historical Center

$116

$128 total

Oct 9 - Oct 10

A courtyard with wooden benches, a laundry service sign, a wooden cart with potted plants, and a large orange door.

A spacious interior with a wooden bench, a cart with plants, and a sign for laundry service.

A breakfast setting with bread, cheese, fruits, coffee, and juice on a table.

A multi-level interior with potted plants, a laundry service sign, and a wooden bench.

18. Hostal Villa Sillar

Historical Center

$37

$37 total

Oct 6 - Oct 7

A courtyard with stone flooring, a central door with a decorative arch, and potted plants.

A stone staircase leading to a small waterfall, surrounded by greenery and a rustic stone wall.

A bedroom with a brick wall, a bed with a metal headboard, a chandelier, and a mirror.

A table with a cup, teapot, plate of fruit, and croissant, overlooking a cityscape.

19. Acolpacha - Tambo Boutique

Historical Center

$74

$81 total

Nov 3 - Nov 4

A rooftop patio with round wooden tables and chairs, potted plants, and umbrellas.

A modern building with a sign reading "CASA ANDINA" and the number "603".

A hotel room with a bed, desk, chair, TV, ceiling fan, window, and nightstand.

A buffet area with various food items, a flat-screen TV, and a decorative plant.

20. Casa Andina Standard Arequipa

Historical Center

$87

$96 total

Oct 11 - Oct 12

View all properties

Go beyond your typical stay in Mosopuquio

Check out reviews of Mosopuquio hotels guests love

Hotel El Lago by Luoxo

Sabandía

10/10 Exceptional

sarah

Sonesta Hotel Arequipa

Cerro Colorado District

10/10 Exceptional

hugo

A pathway leading through a garden with a stone border, surrounded by greenery and potted plants.

A stone staircase leading to a glass bridge, surrounded by lush greenery and flowering plants.

A dining area with wooden furniture, a chandelier, and a floral-patterned ceiling.

Villa Elisa Hotel Boutique with a white facade, blue shutters, and a tiled roof.

Hotel Boutique Villa Elisa

Historical Center

10/10 Exceptional

Luis Agustin

Los Tambos - Boutique

Historical Center

10/10 Exceptional

My experience with Los Tambos started from the moment we booked via Expedia. Immediately, Vanessa followed up with a welcome note. When I inquired about tours to Colca Canyon, which we had trouble booking online without a Western Union transfer, she connected us with a guide and recommended a hotel in the canyon. Our experience on that excursion was incredible. Our experience at Los Tambos itself was also remarkable. Very competent, truly charming staff! When we checked-in, Diego welcomed...

Danielle

HOTEL AREQUIPA INN

Historical Center

10/10 Exceptional

Camilo

Hampton by Hilton Arequipa

Historical Center

10/10 Exceptional

Marcel

ARIQUEPAY HOTEL

Historical Center

10/10 Exceptional

This hotel is gorgeous, super clean, and perfectly located. The beds, pillows, and linens are luxurious, providing a true 5-star experience during our 5-night stay. We enjoyed drinks on the rooftop with stunning views of Plaza del Armas, and the pizza was delicious! Highly recommended! Tip: If you use the laundry service, be sure to separate your darks from whites, as they wash everything together.

Elisha

A courtyard with a pool, stone walls, and arched doorways.

A room with a stone ceiling, a bathtub, a wooden chair, a bookshelf, and a mirror.

A bedroom with a four-poster bed, wooden furniture, and a large painting on the wall.

A bathroom with a bathtub, a large ornate mirror, a wooden vanity, and a bed with a wooden headboard.

Palacio Guaqui

Historical Center

10/10 Exceptional

Fiorella

A room with a bed, a table with a vase, and a chandelier.

A cozy room with a green armchair, a small table with a vase of flowers, and a lamp.

An outdoor dining area with tables and chairs, a rustic stone wall, and a large window.

A hotel room with a large bed, a chandelier, and arched windows with curtains.

CIRQA by Andean

Historical Center

10/10 Exceptional

This is one of the best hotels I have ever had the pleasure to stay in. The architecture is amazing. The design of the rooms is even better. The food is beyond belief. The staff is incredibly helpful, smiling and friendly. The breakfast is to die for. I truly cannot recommend this hotel enough. You will not only not be disappointed, but you will be elated at the level of comfort, delicious food and impeccable staff.

Paulette

A courtyard with wicker furniture, potted plants, and a tiled floor.

The entrance to El Conquistador Hotel with a wooden door, a sign above the door, and multiple flags on the roof.

A lobby with wicker furniture, potted plants, and a stone floor.

A spacious lobby with leather sofas, a red rug, and a wooden dining area.

Los Tambos - Colonial

Historical Center

10/10 Exceptional

Ivan

Hotel Casa Campo by Cassana

Cayma

10/10 Exceptional

John

A multi-level atrium with a central reflective pool, balconies, and a mix of modern and traditional architectural elements.

A wooden table with a bottle of wine and two glasses, a bed, and a view of a room with a bed and a window.

A view from a balcony with a glass door, looking into a courtyard with a curved roof structure and a stone wall.

A spacious lobby with a glass floor, multiple levels with balconies, and wicker furniture.

Palla Boutique Hotel

Historical Center

10/10 Exceptional

Gabriela

An outdoor dining area with tables and chairs, lanterns, and a view of a historic building with two towers and a mountain in the background.

A grand hallway with ornate furniture, a chandelier, and a mirror reflecting the room.

A modern spa room with a massage table, wooden paneling, a sink, and a mirror.

A hotel entrance with ornate wooden doors and a sign reading "KATARI AT PLAZA DE ARMAS".

Katari Hotel At Plaza de Armas

Historical Center

10/10 Exceptional

We loved our six night stay at Katari. The rooms were comfortable with traditional furniture and lovely linens. The location on the Plaza de Armas can’t be beat. The views from the rooftop restaurant and bar are spectacular at all times of the day, but especially at sunset, with the lights on the cathedral coming up and the sun turning the snow capped volcanoes pink. The only thing better are the staff, so kind, warm and responsive. Highly, highly recommend this place!

Nancy

A picnic setup with food and drinks on a wooden table in a grassy area with a tree and a llama in the background.

A swimming pool with a clear blue water, surrounded by a building with a pink facade, and a tree in the foreground.

A spacious lobby with two sofas facing a fireplace, surrounded by tables and chairs, and a large mural on the walls.

A bartender holding a glass with a drink named "BULLDOG" at a bar with a counter and bottles in the background.

Wyndham Costa del Sol Arequipa

Historical Center

10/10 Exceptional

The Hotel is a little bit old. It is not well Lit at all. But the food is outstanding, the staff is amazing. With the exception of the older guy that works at night in the front desk, that guy didn’t seem like he wanted to be bothered at all. Besides that, everybody else went out of their way to help you in anyway they could. I have stayed in five star five diamond hotels, and this has been the best staff I have ever experienced. Well done. The staff is by far the star of all of this.

William

An outdoor dining area with tables and chairs, a view of a church with a bell tower, and a clear blue sky.

A breakfast buffet with various food items and a sign indicating a capacity of 93 people.

A building entrance with a stone facade, arched doorways, and a series of columns.

A reception desk with a sign reading 'CASA ANDINA ELECT' and a 'sama 2Go!' refrigerator.

Casa Andina Select Arequipa Plaza

Historical Center

10/10 Exceptional

Ramon

Acolpacha - Tambo Boutique

Historical Center

10/10 Exceptional

Susan

Mint Hotel

Historical Center

10/10 Exceptional

Juan

A covered patio with wooden flooring, round tables, and chairs. There are arched windows with metal bars and potted plants.

A hotel with a central staircase, a sign reading "Hotel San Felipe Suites," and a gated entrance.

An indoor dining area with round tables and chairs, large arched windows, and potted plants.

A modern living room with three armchairs, a round coffee table, and a large abstract painting on the wall.

Hotel San Felipe Suites

Yanahuara

10/10 Exceptional

Layne

A modern building with a staircase leading to a second floor. There are potted plants and a framed artwork on the wall.

A modern interior with a staircase leading to an upper level, surrounded by tall potted plants and a checkered floor.

A hotel lobby with a glass door entrance, a chandelier, and red seating.

Tierra Viva Arequipa Plaza

Historical Center

10/10 Exceptional

Ernie

Frequently Asked Questions

What hotels do travelers recommend in Mosopuquio?

Guests like Hotel El Lago by Luoxo.

Can I book a refundable hotel in Mosopuquio?

If you're looking for the flexibility to change your travel plans to Mosopuquio, most hotels provide refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Mosopuquio be like during my trip?

September and October are typically the warmest months in Mosopuquio when the average temp is 58°F. July and June are the coldest months when the average temperature is 56°F. February and January are the months with the most rain.

Why should I book my Mosopuquio hotel with Hotels.com?

There are lots of reasons to book your Mosopuquio trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.