Hotels in South Carolina Lowcountry

Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices

Check prices for these dates

Tonight
May 21 - May 22
Tomorrow
May 22 - May 23
This weekend
May 23 - May 25
Next weekend
May 30 - Jun 1

Where to stay in South Carolina Lowcountry?

Red Roof Inn Yemassee
Lobby

Red Roof Inn Yemassee

2.0 star property
7.6 out of 10, Good, (549)
The price is $74
$81 total
includes taxes & fees
May 22 - May 23
Red Roof Inn Yemassee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in South Carolina Lowcountry, SC

Showing deals for:May 30 - Jun 1

Image gallery for The Westin Hilton Head Island Resort & Spa

2 bars/lounges, poolside bar

The Westin Hilton Head Island Resort & Spa

4.0 star property
Hilton Head Island
8.4/10Very Good (1,001 reviews)
14% off
Price is $1,054
$441 nightly
$1,054 total
Total includes taxes and fees
The Westin Hilton Head Island Resort & Spa

Top neighborhoods in South Carolina Lowcountry

Default Image

Sea Pines

Hilton Head Island's Sea Pines neighborhood has a host of places to visit such as Atlantic Dunes by Davis Love III and Harbour Town Golf Links.

See properties in Sea Pines
Sea Pines

Top landmarks in South Carolina Lowcountry

Marine Corps Recruit Depot Parris Island

Marine Corps Recruit Depot Parris Island

Marine Corps Recruit Depot Parris Island is worth a visit, located 0.6 mi (0.9 km) from central Parris Island. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.

See properties in Marine Corps Recruit Depot Parris Island
Marine Corps Recruit Depot Parris Island

Learn more about South Carolina Lowcountry

South Carolina Lowcountry is applauded for its cultural attractions such as Parris Island Museum and Highway 21 Drive-In Theater.

See all hotels in South Carolina Lowcountry
Hilton Head featuring heritage architecture
Photo by Hilton Head Island Visitor & Convention Bureau
Open Photo by Hilton Head Island Visitor & Convention Bureau

Frequently asked questions

Can I book refundable hotels in South Carolina Lowcountry?
If you want the flexibility to change your travel plans to South Carolina Lowcountry, most hotels provide refundable* bookable rates. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in South Carolina Lowcountry if I want a vacation home instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 4188 vacation homes. In addition, there are 225 apartments and 3043 condos.
Why should I book my South Carolina Lowcountry accommodation with Hotels.com?
There are lots of reasons to book your South Carolina Lowcountry trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.