The Hilton Garden Inn (HGI) is an excellent hotel. The rooms are spacious by Frankfurt standards, the staff is very friendly and helpful, the facility is well maintained and the internet was flawless. I have only good things to say about the hotel itself. (As an aside, this is my first stay at this particular HGI in Frankfurt. I have stayed at the HGI located at Frankfurt airport FRA above the railway station several times, and can recommend that HGI as well.) All that said, the local neighborhood of this HGI is questionable. Between the HGI and the rail-station (about a 8-10 minute walk) is the Frankfurt red-light district. I was accosted more than once by street people and people-of-the-evening. In every direction other than towards the train-station, the neighborhood is just fine. The HGI borders on the downtown business district - and that is just fine. I did not dine at the hotel as I typically will shop locally. As you exit the front of the HGI turn right and two blocks on the right (on the corner) is an excellent small market open until 11:00 pm. Running is fairly good. Again, as you exit the front of the HGI, turn right and go about 5 or 6 blocks and you arrive at the Main river. There are bicycle-walking-running paths on both sides of the river with several bridges across the river.