Hotels in Seneca

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Oct 16 - Oct 18

Where to stay in Seneca?

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.

A modern lobby with a reception desk, seating area, and a vending machine.

1. Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

$120

$132 total

includes taxes & fees

Oct 11 - Oct 12

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.

A reception area with a counter, chairs, and a patterned rug.

A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

2. Hampton Inn & Suites Seneca-Clemson Area

Seneca

$120

$132 total

includes taxes & fees

Oct 11 - Oct 12

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

3. Quality Inn Seneca US-123

Seneca

$76

$89 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

A reception area with a brick wall, a reception desk, and a glass door leading outside.

4. Best Western Seneca-Clemson

Seneca

$94

$103 total

includes taxes & fees

Oct 28 - Oct 29

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

A spacious dining area with a long wooden table and patterned upholstered chairs.

5. Lakeside Lodge Clemson

Seneca

$109

$135 total

includes taxes & fees

Oct 7 - Oct 8

An outdoor patio area with a fire pit, seating, and string lights.

A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.

A food court with a beverage display, seating area, and a Clemson University sign.

A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

6. Tru by Hilton Seneca Clemson

Seneca

$106

$116 total

includes taxes & fees

Oct 18 - Oct 19

A modern dining area with a high ceiling, large windows, and a buffet setup.

A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

A Days Inn reception area with a view of the parking lot and trees.

A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

7. Days Inn by Wyndham Seneca / Clemson Area

Seneca

$83

$91 total

includes taxes & fees

Oct 8 - Oct 9

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

A wooden interior with a table, chair, and a hanging lantern.

Private kitchen

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

$93

$146 total

includes taxes & fees

Nov 5 - Nov 6

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

A modern bar area with a wooden ceiling, green bar stools, and a bar counter.

An outdoor patio with wicker furniture, a round table, and a fountain.

A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

9. The Shepherd Hotel Downtown Clemson

Clemson

$209

$232 total

includes taxes & fees

Oct 13 - Oct 14

A modern kitchen area with a bar counter and seating.

A Hampton Inn with a modern design, featuring a prominent entrance and outdoor seating area.

A vending area with snacks and beverages, including chips and soda.

A modern living room with a grey sofa, purple and orange cushions, a coffee table with magazines, and a large window with patterned curtains.

10. Hampton Inn Clemson-University Area

Clemson

$110

$122 total

includes taxes & fees

Oct 12 - Oct 13

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

A tiger mascot holding a sign with "HOWARD'S ROCK" text, a staircase, and a desk with a computer.

A wall with a decorative design featuring a building, trees, and a sky with clouds.

A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.

11. Inn @ Clemson

Clemson

$89

$99 total

includes taxes & fees

Oct 7 - Oct 8

A golf course with a water body, trees, and a distant view of a bridge.

An outdoor patio with tables and chairs, surrounded by trees and a view of a body of water.

A modern building with a central entrance, surrounded by a well-maintained lawn and trees.

A golf course with a clubhouse, surrounded by dense trees and a large body of water.

12. Clemson University's James F. Martin Inn

Clemson

$149

$165 total

includes taxes & fees

Oct 7 - Oct 8

A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

A spacious indoor area with multiple levels of balconies, seating areas, and a central open space.

A hotel room with a bed, a desk, a TV, a mirror, and a nightstand with a lamp.

A spacious indoor area with multiple seating arrangements, a ping pong table, and a bar area with purple accents.

13. Best Western Plus Clemson Hotel & Conference Center

Clemson

$105

$117 total

includes taxes & fees

Oct 8 - Oct 9

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

A bar area with a counter, multiple chairs, and a display of bottles and glasses.

A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.

14. The Abernathy of Clemson

Clemson

$161

$179 total

includes taxes & fees

Oct 18 - Oct 19

A kitchen with a coffee maker, microwave, and refrigerator.

A red brick building with a white porch and columns, a door, and windows.

A hotel room with a bed, a desk with a chair, a television, a small table, and a microwave.

A hotel room with a large bed, a bedside table, a nightstand, and a wall-mounted lamp.

15. Rodeway Inn & Suites Walhalla

Walhalla

$76

$85 total

includes taxes & fees

Nov 4 - Nov 5

A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

A modern living room with a flat-screen TV, a desk with a chair, an orange sofa, and a framed tiger picture on the wall.

A conference room with a large round table, multiple chairs, and a projector.

A hotel room with a large bed, a desk, a chair, a mirror, and a framed picture on the wall.

16. Holiday Inn Express & Suites Clemson by IHG

Clemson

$129

$143 total

includes taxes & fees

Oct 11 - Oct 12

Room

A modern kitchen with a microwave, toaster, and coffee maker. There are white bowls and a coffee station.

A spacious room with a large window, a flat-screen TV mounted on the wall, and a seating area with sofas and chairs.

A hotel reception area with two reception desks, a digital screen, and a tiled floor.

17. Comfort Inn & Suites Clemson - University Area

Clemson

$107

$119 total

includes taxes & fees

Oct 18 - Oct 19

A modern bar area with a menu board, bar stools, and a countertop with various items.

A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.

A modern dining area with a bar, bar stools, and a patterned rug.

An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.

18. Courtyard Marriott Clemson

Clemson

$125

$139 total

includes taxes & fees

Oct 18 - Oct 19

A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

A gazebo with a tiled roof and wooden pillars, surrounded by a fence and potted plants.

A hotel room with two beds, a desk, a chair, a TV, and a painting on the wall.

A gazebo with a tiled roof and a surrounding gravel area.

19. Days Inn by Wyndham Clemson

Clemson

$80

$89 total

includes taxes & fees

Oct 7 - Oct 8

A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

A hotel lobby with a long corridor, seating areas, and a reception desk.

A brick building with a sign reading "The Inn at Patrick Square".

A modern restaurant with a marble-top dining table, blue upholstered chairs, and a variety of food items displayed in the background.

20. The Inn at Patrick Square

Clemson

$149

$165 total

includes taxes & fees

Oct 7 - Oct 8

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A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

Quality Inn Seneca US-123

Seneca

$90

per night

$105 total

includes taxes & fees

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.

A reception area with a counter, chairs, and a patterned rug.

A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

Hampton Inn & Suites Seneca-Clemson Area

Seneca

$134

per night

$147 total

includes taxes & fees

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.

A modern lobby with a reception desk, seating area, and a vending machine.

Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

$139

per night

$153 total

includes taxes & fees

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

A reception area with a brick wall, a reception desk, and a glass door leading outside.

Best Western Seneca-Clemson

Seneca

$119

per night

$131 total

includes taxes & fees

A modern dining area with a high ceiling, large windows, and a buffet setup.

A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

A Days Inn reception area with a view of the parking lot and trees.

A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

Days Inn by Wyndham Seneca / Clemson Area

Seneca

$90

per night

$99 total

includes taxes & fees

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

A spacious dining area with a long wooden table and patterned upholstered chairs.

Lakeside Lodge Clemson

Seneca

$109

per night

$135 total

includes taxes & fees

An outdoor patio area with a fire pit, seating, and string lights.

A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.

A food court with a beverage display, seating area, and a Clemson University sign.

A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

Tru by Hilton Seneca Clemson

Seneca

$139

per night

$153 total

includes taxes & fees

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

A wooden interior with a table, chair, and a hanging lantern.

Private kitchen

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

$114

per night

$169 total

includes taxes & fees

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

Quality Inn Seneca US-123

Seneca

$90

per night

$105 total

includes taxes & fees

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.

A reception area with a counter, chairs, and a patterned rug.

A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

Hampton Inn & Suites Seneca-Clemson Area

Seneca

$134

per night

$147 total

includes taxes & fees

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.

A modern lobby with a reception desk, seating area, and a vending machine.

Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

$139

per night

$153 total

includes taxes & fees

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

A reception area with a brick wall, a reception desk, and a glass door leading outside.

Best Western Seneca-Clemson

Seneca

$119

per night

$131 total

includes taxes & fees

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

A spacious dining area with a long wooden table and patterned upholstered chairs.

Lakeside Lodge Clemson

Seneca

$109

per night

$135 total

includes taxes & fees

A modern dining area with a high ceiling, large windows, and a buffet setup.

A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

A Days Inn reception area with a view of the parking lot and trees.

A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

Days Inn by Wyndham Seneca / Clemson Area

Seneca

$94

per night

$103 total

includes taxes & fees

An outdoor patio area with a fire pit, seating, and string lights.

A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.

A food court with a beverage display, seating area, and a Clemson University sign.

A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

Tru by Hilton Seneca Clemson

Seneca

$139

per night

$153 total

includes taxes & fees

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

A wooden interior with a table, chair, and a hanging lantern.

Private kitchen

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

$114

per night

$169 total

includes taxes & fees

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

Quality Inn Seneca US-123

Seneca

$107

per night

$250 total

includes taxes & fees

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.

A modern lobby with a reception desk, seating area, and a vending machine.

Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

$259

per night

$570 total

includes taxes & fees

A modern dining area with a high ceiling, large windows, and a buffet setup.

A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

A Days Inn reception area with a view of the parking lot and trees.

A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

Days Inn by Wyndham Seneca / Clemson Area

Seneca

$132

per night

$290 total

includes taxes & fees

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

A reception area with a brick wall, a reception desk, and a glass door leading outside.

Best Western Seneca-Clemson

Seneca

$212

per night

$466 total

includes taxes & fees

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.

A reception area with a counter, chairs, and a patterned rug.

A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

Hampton Inn & Suites Seneca-Clemson Area

Seneca

$324

per night

$713 total

includes taxes & fees

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

A wooden interior with a table, chair, and a hanging lantern.

Private kitchen

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

$309

per night

$768 total

includes taxes & fees

A clear lake with a rocky shoreline and a tree branch overhanging the water.

A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a dishwasher.

A grassy area with trees and a body of water.

A wooden deck with a view of a forested area and a building with a sloped roof.

6 Mi to South Cove Boat Ramp! Lake Keowee Escape

Seneca

$222

per night

$719 total

includes taxes & fees

A covered deck with wooden beams, wicker furniture, and large windows overlooking a lake.

A single-story house with a covered porch, a driveway, and a view of the water.

A dining area with a wooden table set for four, surrounded by chairs. A fireplace is visible in the background, and there is a large window providing a view of the outdoors.

A modern kitchen with a built-in stove, stainless steel appliances, and patterned flooring.

Stunning Seneca Home w/ Lake Keowee Access!

Seneca

$578

per night

$1,568 total

includes taxes & fees

A wooden deck with a metal roof, overlooking a lake and houses.

A modern multi-story building with a wooden staircase leading up to a balcony, surrounded by trees.

A modern kitchen with a central island, a dining area with a wooden table and chairs, a grey sofa, and a ceiling fan.

A wooden bridge leading to a house with a view of a lake.

Lake Keowee Gem! Close to Clemson & Hiking Trails

Seneca

$513

per night

$1,390 total

includes taxes & fees

A covered patio with wooden chairs and a table, overlooking a fenced yard with a body of water and trees.

A two-story house with a dark roof, a garage, and a large rock in the foreground.

A spacious living area with a sofa set, a glass coffee table, and a ceiling fan.

A modern kitchen with white cabinets, a stainless steel refrigerator, a microwave, a stove, and a dishwasher.

Lakefront Seneca Vacation Rental w/ Shared Dock!

Seneca

$395

per night

$1,071 total

includes taxes & fees

Check out pet-friendly hotels in Seneca

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

A spacious dining area with a long wooden table and patterned upholstered chairs.

Lakeside Lodge Clemson

Seneca

$109

$135 total

includes taxes & fees

Oct 7 - Oct 8

An outdoor patio area with a fire pit, seating, and string lights.

A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.

A food court with a beverage display, seating area, and a Clemson University sign.

A modern hotel with a prominent 'tru by Hilton' sign, a well-lit entrance, and a parking area.

Tru by Hilton Seneca Clemson

Seneca

$106

$116 total

includes taxes & fees

Oct 18 - Oct 19

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

Quality Inn Seneca US-123

Seneca

$76

$89 total

includes taxes & fees

Oct 18 - Oct 19

A modern dining area with a high ceiling, large windows, and a buffet setup.

A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

A Days Inn reception area with a view of the parking lot and trees.

A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

Days Inn by Wyndham Seneca / Clemson Area

Seneca

$83

$91 total

includes taxes & fees

Oct 8 - Oct 9

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

A wooden interior with a table, chair, and a hanging lantern.

Private kitchen

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

$93

$146 total

includes taxes & fees

Nov 5 - Nov 6

View all properties

You can also stay at hotels with a pool in Seneca

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

A deck with outdoor seating overlooking a body of water, adjacent to a building with multiple windows.

A modern lobby with a reception desk, seating area, and a vending machine.

Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

$120

$132 total

includes taxes & fees

Oct 11 - Oct 12

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.

A reception area with a counter, chairs, and a patterned rug.

A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

Hampton Inn & Suites Seneca-Clemson Area

Seneca

$120

$132 total

includes taxes & fees

Oct 11 - Oct 12

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

A spacious dining area with a long wooden table and patterned upholstered chairs.

Lakeside Lodge Clemson

Seneca

$109

$135 total

includes taxes & fees

Oct 7 - Oct 8

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

A spacious lobby with a high ceiling, a chandelier, framed artwork, a lamp, a sofa, and a view through large glass doors to an outdoor area.

A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

Quality Inn Seneca US-123

Seneca

$76

$89 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A multi-story hotel with a prominent entrance, parking area, and a car parked in front.

A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

A reception area with a brick wall, a reception desk, and a glass door leading outside.

Best Western Seneca-Clemson

Seneca

$94

$103 total

includes taxes & fees

Oct 28 - Oct 29

A modern dining area with a high ceiling, large windows, and a buffet setup.

A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

A Days Inn reception area with a view of the parking lot and trees.

A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

Days Inn by Wyndham Seneca / Clemson Area

Seneca

$83

$91 total

includes taxes & fees

Oct 8 - Oct 9

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Go beyond your typical stay in Seneca

Pet friendly

Pool

Apartment

Cottage

Family friendly

Our prices for hotels in Seneca are cheapest in December

Top neighborhoods in Seneca

A lakeside scene with autumn foliage, a clear sky, and a sunset.

A large lake surrounded by dense forests.

Downtown

Downtown Seneca charms visitors with well-preserved historical buildings that tell the story of its railroad heritage. The tree-lined Ram Cat Alley showcases local history through colorful murals, while the old courthouse square hosts seasonal farmers markets and community events. You can explore the Bertha Lee Strickland Cultural Museum or browse antique shops filled with Southern treasures. Family-owned cafes serve up delicious Southern comfort food like fried green tomatoes and barbecue. Accommodations range from historic bed & breakfasts in Victorian homes to budget-friendly motels. The entire downtown is walkable with wide sidewalks, making it easy to discover this authentic slice of small-town America at your own pace.

A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

Lake Keowee beckons from this peaceful coastal retreat nestled in Saxony Forest. Serenity Bay lives up to its name with tree-lined streets perfect for contemplative walks. Nearby Keowee Key Golf Course offers tee times for enthusiasts, while South Beach provides sandy relaxation without the crowds. The natural setting creates an ideal escape for bird watchers and nature photographers. Vacation rentals with weathered wood siding and muted earth tones blend seamlessly into the forest canopy. Getting around requires your own wheels since public transit is limited. The neighborhood trades bustling nightlife for cricket choruses and ocean breezes filtering through pine trees—exactly what makes this hidden gem worth finding.

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

Lake Keowee sparkles as the crown jewel of Pine Ridge Point, a peaceful residential haven in Seneca. Waterfront vacation homes nestle among tall pines, offering private docks and stunning views. Visitors spend days swimming in crystal-clear waters, boating across the lake, or simply unwinding on expansive decks beneath Carolina blue skies. This neighborhood is all about authentic lakeside living without commercial distractions. Most travelers cook in well-equipped rental kitchens or drive 15 minutes to Seneca for restaurants. Personal vehicles are essential for getting around, though scenic paths along the shoreline make for perfect evening strolls.

Indian Oaks

Indian Oaks gives you all the peaceful vibes of suburban life with none of the tourist chaos. This leafy neighborhood in Seneca lets you live like a local under a canopy of mature oak trees. The curved streets and manicured lawns create a park-like setting that's perfect for morning walks. Lake Keowee is just a short drive away when you need a water fix. You'll need wheels to get around since public transit is limited and restaurants aren't within walking distance. Most visitors stay in vacation rental homes with private yards and driveways. The neighborhood gets incredibly quiet after dark—ideal for travelers who want to experience authentic suburban living while having Seneca's attractions nearby.

Top landmarks in Seneca

A waterfall surrounded by autumn foliage.

High Falls County Park

High Falls County Park is worth a visit, located 7.8 mi (12.5 km) from central Seneca.

A grassy field with yellow flowers and trees in the foreground, with mountains in the background.

Blue Ridge Field

Blue Ridge Field is worth a visit, located 0.8 mi (1.2 km) from central Seneca.

Friendship Recreation Area

Friendship Recreation Area is worth a visit, located 6.5 mi (10.5 km) from central Seneca.

Toy Train Park

Toy Train Park is worth a pic or two when discovering Downtown.

Highpointe Field

Highpointe Field is worth a visit, located 5.6 mi (8.9 km) from central Seneca.

Oconee County Library Seneca Branch

Oconee County Library Seneca Branch is worth a pic or two when discovering Downtown.

South Cove Park

South Cove Park is worth a visit, located 2 mi (3.3 km) from central Seneca.

World of Energy

If museums are on your list of things to see in Seneca, then you might want to head to World of Energy. If you want to experience more of the culture Seneca has to offer, head to Lake Keowee, Keowee Key Golf Course, and High Falls County Park.

Learn more about Seneca

Between the crystal waters of Lake Keowee and the misty cascade of Isaqueena Falls lies a playground for outdoor enthusiasts. Kayak across the lake while keeping an eye out for bald eagles soaring overhead and blue herons stalking the shallows. The lush forests of Oconee State Park offer hiking trails for every skill level, with shade-dappled paths winding through ancient trees. Twin Lakes Recreation Area provides family-friendly spots to picnic after a morning on the water. Dog owners shouldn't miss The Pier Dog Park, where four-legged friends can splash along the shoreline. After a day of adventure, the coffeehouses in the historic downtown offer the perfect place to recharge while planning tomorrow's excursion to Keowee Key Golf Course or Lake Hartwell.

See all hotels in Seneca

A sunset over a lake surrounded by dense forests and residential areas.

Check out reviews of Seneca hotels guests love

Quality Inn Seneca US-123

Quality Inn Seneca US-123

8/10 Good

"Second time here! Staff great! This time my room smelled of smoke as a non smoking room! Comforter was clean but from a smoking room and smelled despite it being clean!"

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent

"Great place to stay when visiting Clemson!"

Best Western Seneca-Clemson

Best Western Seneca-Clemson

8/10 Good

"Stayed @ hotel for a football weekend. Hotel was awesome...one of the cleanest I've ever stayed in regardless of hotels' star ratings. The only reason I gave it 4 stars was two things....#1 The bed was a bit too hard for me. I'm used to softer mattresses, but these were a little too hard for me. #2....There was one staff person that was just not very friendly @ the front desk for part of my stay. She wasn't rude & she fulfilled my requests, but she just was not as outgoing as other team members & that stuck out to me. Would I stay at this hotel again? Absolutely...it's been many yrs since I've stayed in a BW...I tend to stay in the upper crust hotels, so I was very pleasantly surprised! Great job Best Western!!"

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

10/10 Excellent

"Staff was great! Room was clean!"

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"We were in town for parents weekend. Only reasonably priced accommodation. At first I was surprised at how remote the cabins were. But I understand it’s on purpose for people that want to disconnect and enjoy nature. We had no problem finding the place. It was clean. It was cozy. It was an adventure!"

Frequently asked questions

What accommodations do travelers like in Seneca?

Guests like Lakeside Lodge Clemson, Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy and Quality Inn Seneca US-123.

Can I book refundable accommodations in Seneca?

If you want the flexibility to change your travel plans to Seneca, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Seneca if I want a budget-friendly accommodation?

Lakeside Lodge Clemson, Quality Inn Seneca US-123 and Hampton Inn & Suites Seneca-Clemson Area are a few accommodations you might want to consider that'll save you money.

Where can I stay in Seneca if I want a vacation rental instead of a hotel?

If you want to find a good alternative to a hotel, review our selection of 217 vacation homes. In addition, there are 24 apartments and 13 condos.

What will the weather in Seneca be like during my visit?

The warmest months in Seneca are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are December and January.

Why should I book my Seneca hotel with Hotels.com?

There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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