Hotels in Cape Girardeau

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Check prices for these dates

Tonight
Oct 16 - Oct 17
Tomorrow
Oct 17 - Oct 18
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Where to stay in Cape Girardeau?

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Oct 22 - Oct 23
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A hotel room with two beds, a desk, a chair, and a view of the city.

2. The Riverview

The Riverview
Cape Girardeau
$114
$129 total
includes taxes & fees
Oct 18 - Oct 19
The Riverview
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

3. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
$90
$102 total
includes taxes & fees
Nov 1 - Nov 2
Drury Inn & Suites Cape Girardeau
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.
A spacious living room with a sofa set, a coffee table, and a dining area.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

4. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
$125
$142 total
includes taxes & fees
Oct 25 - Oct 26
Courtyard by Marriott Cape Girardeau Downtown
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

5. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
$95
$108 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
An outdoor patio with stone walls, wicker furniture, and large windows.
A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

6. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
$106
$119 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn Cape Girardeau I 55 East
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

7. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$72
$81 total
includes taxes & fees
Oct 25 - Oct 26
Pear Tree Inn Cape Girardeau West
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

8. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
$101
$114 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.
A hotel room with a bed, a TV, a desk, and a chair.
A hotel patio with a gazebo, outdoor seating, and a view of the road.

9. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
$72
$87 total
includes taxes & fees
Nov 1 - Nov 2
Candlewood Suites Cape Girardeau by IHG
A modern retail area with a display of local items and snacks.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

10. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
$89
$102 total
includes taxes & fees
Oct 22 - Oct 23
Tru By Hilton Cape Girardeau
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.
A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
$59
$67 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Cape Girardeau North
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A bathroom with a marble wall and a white bathtub.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.
A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

12. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
$70
$82 total
includes taxes & fees
Oct 19 - Oct 20
Town House Inn Cape Giradreau
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
A hotel room with two beds, a nightstand, a lamp, and a chair.

13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
$80
$86 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.
A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.
A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.
A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

14. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
Jackson
$76
$82 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Suites Jackson-Cape Girardeau
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.
A hotel room with two beds, a brick wall, and a wooden headboard.
A restaurant with a brick wall, a flat-screen TV, and a bar area.

15. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
$80
$85 total
includes taxes & fees
Nov 1 - Nov 2
Drury Inn & Suites Jackson MO
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.
A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.
A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.
A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

16. Town House Inn

Town House Inn
Jackson
$71
$77 total
includes taxes & fees
Oct 18 - Oct 19
Town House Inn
A living room with a blue wall, a fireplace, a sofa, and a chair.
A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.
A bar area with stools and a counter where a bartender is serving drinks.
A brick building with a sign reading "Mercantile & Hotel".

17. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
$105
$114 total
includes taxes & fees
Oct 18 - Oct 19
EC Reed's Mercantile and Hotel
A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.
A stone building with a patio area, string lights, and outdoor seating.
A cozy living room with a brown leather sofa, a wooden coffee table, and a window with a view of trees.
A cozy log cabin interior with a wooden staircase, a cushioned sofa, a small table, and a lamp.

18. Makanda Inn

Makanda Inn
Makanda
$262
$299 total
includes taxes & fees
Oct 19 - Oct 20
Makanda Inn
View all properties

You may also like family-friendly hotels in Cape Girardeau

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Oct 22 - Oct 23
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
$95
$108 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
$90
$102 total
includes taxes & fees
Nov 1 - Nov 2
Drury Inn & Suites Cape Girardeau
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.
A spacious living room with a sofa set, a coffee table, and a dining area.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
$125
$142 total
includes taxes & fees
Oct 25 - Oct 26
Courtyard by Marriott Cape Girardeau Downtown
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
An outdoor patio with stone walls, wicker furniture, and large windows.
A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
$106
$119 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn Cape Girardeau I 55 East
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A hotel room with two beds, a desk, a chair, and a view of the city.

The Riverview

The Riverview
Cape Girardeau
$114
$129 total
includes taxes & fees
Oct 18 - Oct 19
The Riverview
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$72
$81 total
includes taxes & fees
Oct 25 - Oct 26
Pear Tree Inn Cape Girardeau West
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
$101
$114 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.
A hotel room with a bed, a TV, a desk, and a chair.
A hotel patio with a gazebo, outdoor seating, and a view of the road.

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
$72
$87 total
includes taxes & fees
Nov 1 - Nov 2
Candlewood Suites Cape Girardeau by IHG
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.
A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
$59
$67 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Cape Girardeau North
View all properties

You can also stay at pet-friendly hotels in Cape Girardeau

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
$90
$102 total
includes taxes & fees
Nov 1 - Nov 2
Drury Inn & Suites Cape Girardeau
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
$100
$113 total
includes taxes & fees
Oct 22 - Oct 23
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
An outdoor patio with stone walls, wicker furniture, and large windows.
A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
$106
$119 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn Cape Girardeau I 55 East
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
$72
$81 total
includes taxes & fees
Oct 25 - Oct 26
Pear Tree Inn Cape Girardeau West
A modern retail area with a display of local items and snacks.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
$89
$102 total
includes taxes & fees
Oct 22 - Oct 23
Tru By Hilton Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.
A hotel room with a bed, a TV, a desk, and a chair.
A hotel patio with a gazebo, outdoor seating, and a view of the road.

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
$72
$87 total
includes taxes & fees
Nov 1 - Nov 2
Candlewood Suites Cape Girardeau by IHG
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A bathroom with a marble wall and a white bathtub.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.
A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
$70
$82 total
includes taxes & fees
Oct 19 - Oct 20
Town House Inn Cape Giradreau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in Cape Girardeau are cheapest in December
Price trends for hotels in Cape Girardeau
Pricing is based on two traveler single night rates
View properties in October
Typical weather for Cape Girardeau
October
High 21°C / low 11°C. Sunny most days.
View properties in October
21°
11°
13°
4°
9°
1°
6°
-2°
8°
-1°
14°
5°
19°
9°
25°
15°
30°
20°
32°
21°
31°
20°
28°
17°
Monthly weather averages (˚C)

Top landmarks in Cape Girardeau

A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
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A cable-stayed bridge over a river with a rocky shoreline in the foreground.

Riverfront Bridge Park

8.8/10 (129 reviews)
Riverfront Bridge Park is worth a visit, located 0.7 mi (1.1 km) from central Cape Girardeau.
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Century Casino & Hotel Cape Girardeau

8.4/10 (176 reviews)
Century Casino & Hotel Cape Girardeau is 0.5 mi (0.8 km) from central Cape Girardeau, why not stop by during your stay.
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Hunter Valley Winery

7.4/10 (48 reviews)
Travelers might want a tour of Hunter Valley Winery, just one of the places to visit, and located 9.3 mi (14.9 km) from central Cape Girardeau.
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Riverfront Park

8.0/10 (2 reviews)
Riverfront Park is worth a visit when in central Cape Girardeau.
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Show Me Center

8.6/10 (40 reviews)
You can catch an event at Show Me Center, located 1.1 mi (1.8 km) from central Cape Girardeau.
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Cape Splash Family Aquatic Center

8.6/10 (21 reviews)
Why not give yourself a treat with a trip to Cape Splash Family Aquatic Center, one of the family attractions located 3.1 mi (5.1 km) from central Cape Girardeau. If you have fun at Cape Splash Family Aquatic Center, you'll love Cape Girardeau Conservation Nature Center, located nearby.
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eDen Spa & Salon

7.8/10 (25 reviews)
If massages and hot tubs are your thing, you might want to pamper yourself at eDen Spa & Salon located 0.4 mi (0.6 km) from central Cape Girardeau.
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Learn more about Cape Girardeau

Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Center or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic downtown invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.

See all hotels in Cape Girardeau
A nighttime view of a bridge with its cables illuminated against a starry sky.

Check out reviews of Cape Girardeau hotels guests love

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

8/10 Good
"It was good. No complaints. The walls weren't terrible. No smells. It was clean & nice."
John 1-night trip
Posted 15 hours ago
Hampton Inn Cape Girardeau I 55 East
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"We have stayed at the Pear Tree several times and never disappointed!! Great staff, clean rooms, generous breakfast. A special thanks to Lydia who took extra care to make our last stay remarkable. Thank you."
Sally 1-night trip
Posted 18 hours ago
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"The room was clean, the pillows were great and the bed was comfy. the dinner service and breakfast were very nice and the staff was helpful and friendly! 10/10"
Cynthia 1-night trip
Posted 22 hours ago
Drury Inn & Suites Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"We have stayed here a number of times over 20 years. It’s always clean and well maintained. Breakfast is very good. Staff is always friendly and helpful."
John 3-night trip
Posted 3 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

8/10 Good
"The outside needed cleaning, but the room was very clean and well maintained."
Michael p 1-night trip
Posted 2 months ago
Town House Inn Cape Giradreau

Frequently asked questions

What hotels do travelers recommend in Cape Girardeau?
Guests like Drury Plaza Hotel Cape Girardeau Conference Center, The Riverview and Pear Tree Inn Cape Girardeau West.
Can I book a refundable hotel in Cape Girardeau?
If you need the flexibility to change your travel plans to Cape Girardeau, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Cape Girardeau if I'm looking for an affordable accommodation?
Pear Tree Inn Cape Girardeau West, Candlewood Suites Cape Girardeau by IHG and Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG are a few accommodations you might want to consider that'll save you money.
Where can I stay in Cape Girardeau if I want a vacation rental instead of a hotel?
If you want a good alternative to a hotel, look over our selection of 30 vacation homes. In addition, you can choose from 20 apartments.
What will the weather in Cape Girardeau be like during my vacation?
July and August are typically the warmest months in Cape Girardeau when the average temp is 76°F. January and February are the coldest months when the average temperature is 40°F. April and March are the months with the most rain.
Why should I book my Cape Girardeau hotel through Hotels.com?
There are lots of reasons to book your Cape Girardeau trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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