Top 10 Hotels in Central, SC in 2026 (from $59)

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Where to stay in Central?

Room, 1 King Bed, Non Smoking | Premium bedding, desk, laptop workspace, blackout drapes

1. Comfort Inn & Suites Clemson - University Area

Clemson

$105

$117 total

includes taxes & fees

Oct 8 - Oct 9

2. Best Western Plus Clemson Hotel & Conference Center

Clemson

$101

$112 total

includes taxes & fees

Sep 21 - Sep 22

Double Room, 2 Queen Beds | Desk, soundproofing, iron/ironing board, WiFi (free)

3. Inn @ Clemson

Clemson

$99

$110 total

includes taxes & fees

Sep 20 - Sep 21

4. The Inn at Patrick Square

Clemson

$149

$165 total

includes taxes & fees

Sep 27 - Sep 28

5. Hampton Inn Clemson-University Area

Clemson

$106

$117 total

includes taxes & fees

Sep 27 - Sep 28

Suite, 1 King Bed with Sofa bed (Low Floor) | Desk, blackout drapes, iron/ironing board, WiFi (free)

6. Holiday Inn Express & Suites Clemson by IHG

Clemson

$129

$143 total

includes taxes & fees

Sep 20 - Sep 21

Standard Room, 1 King Bed, Smoking | In-room safe, WiFi (free), bed sheets

Standard Room, 1 King Bed, Non Smoking | In-room safe, WiFi (free), bed sheets

7. Econo Lodge Clemson - University Area

Clemson

$84

$95 total

includes taxes & fees

Oct 8 - Oct 9

Daily cooked-to-order breakfast for a fee

8. Courtyard Marriott Clemson

Clemson

$134

$149 total

includes taxes & fees

Oct 18 - Oct 19

9. Lakeside Lodge Clemson

Seneca

$109

$135 total

includes taxes & fees

Sep 20 - Sep 21

Desk, soundproofing, iron/ironing board, WiFi (free)

10. Days Inn by Wyndham Clemson

Clemson

$85

$94 total

includes taxes & fees

Sep 20 - Sep 21

Seasonal outdoor pool, open 10:00 AM to 9:00 PM, free cabanas

11. Clemson University's James F. Martin Inn

Clemson

$127

$141 total

includes taxes & fees

Sep 20 - Sep 21

Desk, blackout drapes, iron/ironing board, WiFi (free)

12. Tru by Hilton Seneca Clemson

Seneca

$110

$121 total

includes taxes & fees

Oct 11 - Oct 12

Custom King Full | In-room safe, desk, blackout drapes, iron/ironing board

13. The Abernathy of Clemson

Clemson

$161

$179 total

includes taxes & fees

Oct 18 - Oct 19

Signature Cottage, 2 Bedrooms | Living room | 43-inch Smart TV with cable channels, TV, Netflix

Signature Cottage, 2 Bedrooms | Private kitchen | Coffee/tea maker, fridge, microwave, oven

Signature Cottage, 2 Bedrooms | 2 bedrooms, iron/ironing board, WiFi (free), individually decorated

14. Clemson Memorabilia House

Clemson

$89

$238 total

includes taxes & fees

Sep 20 - Sep 21

15. Microtel Inn & Suites by Wyndham Anderson/Clemson

Anderson

$84

$93 total

includes taxes & fees

Sep 30 - Oct 1

Studio Suite, 1 King Bed, Non Smoking | Jetted tub

16. Days Inn by Wyndham Anderson

Anderson

$60

$66 total

includes taxes & fees

Sep 21 - Sep 22

17. Quality Inn Seneca US-123

Seneca

$76

$89 total

includes taxes & fees

Sep 24 - Sep 25

Standard Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board

18. Best Western Seneca-Clemson

Seneca

$97

$107 total

includes taxes & fees

Sep 21 - Sep 22

In-room safe, desk, iron/ironing board, cribs (free)

19. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Anderson

$103

$114 total

includes taxes & fees

Oct 18 - Oct 19

20. Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

$120

$132 total

includes taxes & fees

Sep 27 - Sep 28

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Go beyond your typical stay in Central

Top landmarks in Central

Southern Wesleyan University

10.0/10 (2 reviews)

If you'd like to get a taste of Central student life, check out Southern Wesleyan University, located 1.1 mi (1.8 km) from central Central.

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Lake Issaqueena

Lake Issaqueena is 4.7 mi (7.6 km) from central Central, why not stop by during your stay.

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P. B. Wood Golf Practice Facility

P. B. Wood Golf Practice Facility is 0.9 mi (1.5 km) from central Central, why not stop by during your stay.

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Learn more about Central

Central is well-known for its attractions such as Lake Hartwell and Lake Issaqueena. The city has something for everyone including sights like P. B. Wood Golf Practice Facility within a sunny setting.

See all hotels in Central

Check out reviews of Central hotels guests love

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Anderson

10/10 Exceptional

Ruth

Michele

Frequently Asked Questions

What accommodations do travelers recommend in Central?

Guests like Best Western Plus Clemson Hotel & Conference Center, Comfort Inn & Suites Clemson - University Area and Lakeside Lodge Clemson.

Can I book a refundable accommodation in Central?

If you want the flexibility to change your plans to Central, most properties provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Central if I want a vacation rental instead of a hotel?

If you want to find a good alternative to a hotel, browse our selection of 33 vacation homes. You can also consider one of the 15 apartments or 5 cottages.

What will the weather in Central be like during my vacation?

July and August are typically the warmest months in Central when the average temp is 77°F. January and February are the coldest months when the average temperature is 47°F. December and January are the months with the most rain.

Why should I book my Central hotel through Hotels.com?

There are lots of reasons to book your Central trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.