Hotels in Santa Cruz

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Hotel Finca Las Hortensias
Hotel Finca Las Hortensias
3.0 star property
Tepotzotlán
8.4 out of 10, Very Good, (189 reviews)
This charming Tepotzotlán hotel offers two swimming pools, Mexican cuisine at Los Girasoles restaurant, and a welcoming bar. Just minutes from the Artisan Market and National Museum of the Viceroyalty, with free WiFi and parking for a convenient stay.
The price is $62
$75 total
includes taxes & fees
Apr 28 - Apr 29
Hotel Finca Las Hortensias
La Morada Tepotzotlan Boutique & Spa
La Morada Tepotzotlan Boutique & Spa
3.5 star property
Tepotzotlán
7.6 out of 10, Good, (43 reviews)
Escape to this spa hotel with an outdoor pool and soothing hot stone massages. After a treatment at the full-service spa, enjoy dinner at the restaurant or drinks at the bar. Near Hacienda La Concepcion and Artisan Market with free parking for day trips.
The price is $254
$305 total
includes taxes & fees
Apr 28 - Apr 29
La Morada Tepotzotlan Boutique & Spa
Verticca Hotel
Verticca Hotel
3.0 star property
Ojo de Agua
9.2 out of 10, Wonderful, (281 reviews)
This sleek Tecamac hotel offers convenient access to Felipe Ángeles International Airport and the fascinating Santa Lucía Quinamétzin Paleontological Museum. Enjoy complimentary breakfast, WiFi, and parking while unwinding with a drink after your workout.
The price is $148
$178 total
includes taxes & fees
Apr 28 - Apr 29
Verticca Hotel
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
3.5 star property
Zumpango
9.4 out of 10, Exceptional, (1,122 reviews)
This peaceful oasis offers surprising tranquility despite its airport-adjacent location. Just 1.6 mi from Felipe Ángeles Intl. Airport with free shuttle service, you'll find 2 restaurants and a fitness center. Business travelers appreciate the helpful staff and free WiFi.
The price is $133
$159 total
includes taxes & fees
May 12 - May 13
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
Fiesta Inn Ecatepec
Fiesta Inn Ecatepec
3.5 star property
Ecatepec de Morelos
8.8 out of 10, Excellent, (934 reviews)
Unwind in this convenient Ecatepec de Morelos hotel featuring an indoor pool and international cuisine at Cafe la Fiesta. Just 15 minutes from the famous Basilica and Centro Las Américas with free WiFi and parking for easy city exploration.
The price is $94
$113 total
includes taxes & fees
May 8 - May 9
Fiesta Inn Ecatepec
Hotel Vía la Villa
Hotel Vía la Villa
2.5 star property
Gustavo A. Madero
8.0 out of 10, Very Good, (365 reviews)
Discover Mexico City from this welcoming hotel with free WiFi and 24-hour front desk service. Just a 10-minute drive from the famous Basilica and Zócalo, with Bondojito Station a 13-minute walk away for convenient exploration of nearby Paseo de la Reforma.
The price is $50
$59 total
includes taxes & fees
May 20 - May 21
Hotel Vía la Villa
Hotel Único La Villa
Hotel Único La Villa
2.0 star property
Gustavo A. Madero
7.0 out of 10, Good, (48 reviews)
The price is $43
$52 total
includes taxes & fees
Apr 28 - Apr 29
Hotel Único La Villa
City Express by Marriott Ciudad de México La Villa
City Express by Marriott Ciudad de México La Villa
4.0 star property
Gustavo A. Madero
8.8 out of 10, Excellent, (1,003 reviews)
The price is $66
$79 total
includes taxes & fees
Apr 28 - Apr 29
City Express by Marriott Ciudad de México La Villa
Gran Hotel Villa de Madrid
Gran Hotel Villa de Madrid
3.5 star property
Gustavo A. Madero
8.2 out of 10, Very Good, (477 reviews)
This Mexico City hotel offers 24-hour room service and easy access to Misterios Station, just 7 minutes away by foot. Enjoy free WiFi and parking while being within a short drive of Zócalo and Palacio de Bellas Artes. Savor Mexican cuisine at La Zarzuela restaurant.
The price is $56
$67 total
includes taxes & fees
Apr 28 - Apr 29
Gran Hotel Villa de Madrid
Gran Hotel Panorama
Gran Hotel Panorama
3.0 star property
Cuauhtémoc
8.4 out of 10, Very Good, (1,004 reviews)
The price is $24
$28 total
includes taxes & fees
Apr 28 - Apr 29
Gran Hotel Panorama
Hotel Escala Central del Norte
Hotel Escala Central del Norte
3.0 star property
Gustavo A. Madero
8.2 out of 10, Very Good, (699 reviews)
Located just minutes from Northern Bus Terminal Metro Station, this Mexico City hotel offers easy access to top attractions. Enjoy international cuisine at La Muralla restaurant and take advantage of free WiFi and parking during your stay.
The price is $45
$54 total
includes taxes & fees
Apr 28 - Apr 29
Hotel Escala Central del Norte
Hotel Brasilia
Hotel Brasilia
3.0 star property
Gustavo A. Madero
9.0 out of 10, Wonderful, (1,002 reviews)
Steps from Northern Bus Terminal Metro Station, this Mexico City hotel offers free WiFi and parking. Work out in the fitness center, then relax with a drink at the bar. Within driving distance of Palacio de Bellas Artes and the Angel of Independence Monument.
The price is $63
$75 total
includes taxes & fees
Apr 28 - Apr 29
Hotel Brasilia
Mala Vecindad Centro Historico
Mala Vecindad Centro Historico
3.0 star property
Cuauhtémoc
9.0 out of 10, Wonderful, (89 reviews)
Immerse yourself in Mexico City's historic center at this charming hotel with a welcoming bar and café. Just steps from Garibaldi-Lagunilla Station and a short walk to Palacio de Bellas Artes and Alameda Central. Zócalo and Paseo de la Reforma are only 5 minutes away by car.
The price is $13
$34 total
includes taxes & fees
Apr 30 - May 1
Mala Vecindad Centro Historico
Holiday Inn Express Mexico Basilica by IHG
Holiday Inn Express Mexico Basilica by IHG
3.0 star property
Cuauhtémoc
9.2 out of 10, Wonderful, (1,127 reviews)
The price is $80
$95 total
includes taxes & fees
Apr 30 - May 1
Holiday Inn Express Mexico Basilica by IHG
Hotel Aquario CDMX - Central del Norte
Hotel Aquario CDMX - Central del Norte
3.0 star property
Gustavo A. Madero
7.2 out of 10, Good, (65 reviews)
Conveniently located just 5 minutes from Northern Bus Terminal Metro Station, this hotel offers easy access to Basilica of Our Lady of Guadalupe and Palacio de Bellas Artes. Enjoy 24-hour room service and free parking while exploring Mexico City's iconic landmarks.
The price is $30
$36 total
includes taxes & fees
Apr 28 - Apr 29
Hotel Aquario CDMX - Central del Norte
Hotel MX lagunilla CDMX, Trademark Collection by Wyndham
Hotel MX lagunilla CDMX, Trademark Collection by Wyndham
3.5 star property
Cuauhtémoc
8.4 out of 10, Very Good, (676 reviews)
Just steps from Garibaldi-Lagunilla Station, this Mexico City hotel offers free breakfast, WiFi, and parking. Work out in the fitness center before exploring nearby attractions like Alameda Central, Paseo de la Reforma, and Zócalo.
The price is $43
$51 total
includes taxes & fees
May 3 - May 4
Hotel MX lagunilla CDMX, Trademark Collection by Wyndham
City Express by Marriott Ciudad De México La Raza
City Express by Marriott Ciudad De México La Raza
3.0 star property
Azcapotzalco
8.8 out of 10, Excellent, (1,003 reviews)
Immerse yourself in Mexico City's vibrant culture with free breakfast and WiFi at this conveniently located hotel. Just minutes from La Raza Station and a short drive to iconic Palacio de Bellas Artes and Basilica of Our Lady of Guadalupe.
The price is $73
$87 total
includes taxes & fees
May 24 - May 25
City Express by Marriott Ciudad De México La Raza
KALI La Raza Mexico City
KALI La Raza Mexico City
2.5 star property
Cuauhtémoc
9.2 out of 10, Wonderful, (306 reviews)
Soak in Mexico City's energy at this modern hotel near iconic landmarks. Just minutes from Bellas Artes and Revolution Monument, enjoy complimentary WiFi and parking while staying active in the 24-hour fitness center.
The price is $62
$75 total
includes taxes & fees
Apr 28 - Apr 29
KALI La Raza Mexico City
Downtown Treasure Place
Downtown Treasure Place
2.5 star property
Cuauhtémoc
8.8 out of 10, Excellent, (816 reviews)
This urban retreat serves free breakfast and offers valet parking and WiFi. Located just 9 minutes from Guerrero Station, the condo features fully-equipped kitchenettes. Palacio de Bellas Artes and Zócalo attractions are a short journey away.
The price is $38
$46 total
includes taxes & fees
Apr 28 - Apr 29
Downtown Treasure Place
One Ciudad de Mexico La Raza
One Ciudad de Mexico La Raza
3.0 star property
Cuauhtémoc
8.6 out of 10, Excellent, (1,004 reviews)
Located minutes from Paseo de la Reforma, this Mexico City hotel offers free buffet breakfast, WiFi, and parking. Tlatelolco Station is a 17-minute walk away, connecting you to Palacio de Bellas Artes and Zócalo. The helpful staff receives consistent praise from travelers.
The price is $65
$78 total
includes taxes & fees
May 24 - May 25
One Ciudad de Mexico La Raza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check out reviews of Santa Cruz hotels guests love

Frequently asked questions

What accommodations do travelers like in Santa Cruz?
La Morada Tepotzotlan Boutique & Spa and Hotel Finca Las Hortensias are a couple of accommodations that are popular with guests.
Can I book refundable hotels in Santa Cruz?
If you want the flexibility to change your travel plans to Santa Cruz, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Cruz be like during my vacation?
April and May are typically the warmest months in Santa Cruz when the average temp is 64°F. January and December are the coldest months when the average temperature is 57°F. August and July are the months with the most rain.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.