Hotels in Greenville

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Where to stay in Greenville?

A modern cafe with seating, a coffee machine, and a sign indicating availability of coffee and juice.

A hotel room with a TV mounted on the wall, a microwave, a small refrigerator, a desk with a chair, and a bed.

Reston Inn & Suites

Spencer

$99

$111 total

includes taxes & fees

Aug 30 - Aug 31

A stone fountain in a garden with a building in the background.

A hotel room with a wooden desk, two lamps, a chair, a trash bin, a coffee maker, a television, and framed artwork on the wall.

A living room with patterned armchairs, a red plant, and a mirror on the wall.

Spencer Inn and Suites

Spencer

$99

$111 total

includes taxes & fees

Aug 30 - Aug 31

A building with a large entrance, numbered 1005, and a covered walkway leading to the entrance.

An indoor swimming pool with wooden beams and large windows.

A kitchen area with a chalkboard sign that reads "Think Spring," a waffle maker, a coffee machine, and a display case with pastries.

A modern bathroom with a large bathtub, a television mounted on the wall, and a towel rack with towels.

AmericInn by Wyndham Spencer

Spencer

$76

$85 total

includes taxes & fees

Sep 21 - Sep 22

A Holiday Inn Express & Suites hotel with multiple floors, a parking lot, and a covered entrance.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a sign indicating pool rules.

A hotel lobby with a seating area, a reception desk, and a bar.

A bathroom with a large mirror, a sink, and a towel rack.

Holiday Inn Express & Suites Spencer by IHG

Spencer

$107

$120 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a large bed, a headboard with three pillows, a wall-mounted TV displaying a snowy landscape, and a wooden nightstand with a lamp.

A tan leather sofa in a room with a large painting of a barn on the wall, a water dispenser, and a potted plant.

A framed sign with "Greetings from Iowa" and a cityscape.

The Northwest Inn

Spencer

$84

$94 total

includes taxes & fees

Aug 30 - Aug 31

A hotel room with two beds, a desk, a chair, a sofa, a round mirror, and a large landscape painting on the wall.

A breakfast buffet area with waffle makers, syrup dispensers, and a coffee station.

A hotel room with a sofa, a desk with a chair, a lamp, and a television.

A hotel with a central tower, multiple windows, and a covered entrance.

Emmetsburg Hotel and Suites

Emmetsburg

$69

$78 total

includes taxes & fees

Aug 30 - Aug 31

A modern living room with a fireplace, two sofas, a coffee table, and decorative items on a white rug.

A hotel room with two beds, a desk, a lamp, and a coffee maker.

A modern kitchen with a granite countertop, a bar area with chairs, a flat-screen TV mounted on the wall, and a framed abstract painting above the counter.

A modern lobby with a fireplace, seating area, and reception desk.

Reston Lodge & Suites

Emmetsburg

$79

$88 total

includes taxes & fees

Aug 30 - Aug 31

A hotel lobby with a long marble bar, seating area with sofas and chairs, a reception desk, and a staircase leading to an upper level.

An indoor swimming pool with wooden walls, a lifebuoy, and plastic chairs.

A hotel lobby with a reception desk, wooden cabinets, a sofa, and potted plants.

A living room with patterned sofas, a round coffee table, and leather ottomans.

Rodeway Inn Milford

Milford

$95

$106 total

includes taxes & fees

Aug 31 - Sep 1

A dining area with a table, chairs, a coffee machine, and a potted plant.

A two-story blue house with a sloped roof, white shutters, and a small porch with a flag.

A sign for a suburban Best Value Inn with a high-speed internet advertisement.

A wooden deck with a lattice railing, a tree, and a flower pot.

Americas Best Value Inn Suburban Motel

Emmetsburg

$68

$76 total

includes taxes & fees

Aug 30 - Aug 31

View all properties

Check out reviews of Greenville hotels guests love

Reston Inn & Suites

8/10 Good

"We enjoyed the hotel for the most part. But the beds in our room were really hard and none of us got much sleep while we were there. So if you enjoy extremely firm mattresses, this is your perfect hotel."

Rodeway Inn Milford

10/10 Excellent

"the room was clean the continental breakfast was small but good waffles and muffins and some fruit and juice and bagels and toast"

Americas Best Value Inn Suburban Motel

10/10 Excellent

"I thought the manager was very accommodating and friendly. The rooms were clean and comfortable. The price was very reasonable, and Manny honored our request to have our rooms closer together. Parking was great, right outside of our rooms I would stay there again."

Holiday Inn Express & Suites Spencer by IHG

10/10 Excellent

"K"

Frequently asked questions

What hotels do travelers like in Greenville?

Guests like Reston Inn & Suites, AmericInn by Wyndham Spencer and Holiday Inn Express & Suites Spencer by IHG.

Can I book refundable hotels in Greenville?

If you need the flexibility to change your plans to Greenville, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Greenville be like during my vacation?

The warmest months in Greenville are usually July and August with an average temp of 69°F. January and February are the chilliest months when the average temp is 24°F. The rainiest months are June and May.

Why should I book my Greenville accommodation with Hotels.com?

There are plenty of reasons to book your Greenville travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

More ways to book

Book Hotels in Greenville on Hotels.com