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Hotels in San Antonio Palopo

November 2026
December 2026

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This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Where to stay in San Antonio Palopo?

A coastal property with multiple buildings, a dock, and a clear blue sea.
A round glass table with four chairs in a corner room with large windows.
A window with a view of mountains and a body of water.
A rustic room with a bed, a chair, and a table. There are large windows with a view of greenery outside.

1. Atitlan Oasis Eco Hotel and Spa Kaalpul

Atitlan Oasis Eco Hotel and Spa Kaalpul
San Antonio Palopo
$149
$181 total
includes taxes & fees
Oct 20 - Oct 21
Atitlan Oasis Eco Hotel and Spa Kaalpul
A living room with a large sliding glass door leading to a balcony with a view of the sea and mountains.
A hotel room with a large bed, a balcony with a red railing, and a view of a lake and mountains.
A coastal property with a red-roofed building, a garden with various plants, and a view of the sea.
A cozy living room with a sofa, a coffee table, and a view of the sea through large windows.

2. Hotel La Villa de los Dioses

Hotel La Villa de los Dioses
San Antonio Palopo
$82
$130 total
includes taxes & fees
Oct 20 - Oct 21
Hotel La Villa de los Dioses
A vibrant red building with a white door, surrounded by lush greenery and flowering plants.
A kitchen with a gas stove, a window with a view of greenery, and curtains.
A compact kitchen with wooden cabinets, a white refrigerator, and a red countertop. There are two stools and a small sink.
A narrow room with a wooden bunk bed, a window with patterned curtains, and a tiled floor.

3. Pink house

Pink house
San Antonio Palopo
$54
$71 total
includes taxes & fees
Oct 20 - Oct 21
Pink house
A resort with a swimming pool, a covered patio, and a view of the ocean and mountains.
A cozy living room with a fireplace, sofas, and a coffee table.
A balcony with a table and chairs, overlooking a scenic view of a lake and mountains.
A spacious bedroom with a large bed, wooden ceiling beams, and a view of the sea through an open door.

4. Hotel Villa Santa Catarina

Hotel Villa Santa Catarina
Santa Catarina Palopo
$99
$121 total
includes taxes & fees
Oct 20 - Oct 21
Hotel Villa Santa Catarina
A balcony with a view of a swimming pool, outdoor seating, and a mountainous landscape.
A dining area with tables set for a meal, overlooking a scenic view of a volcano and the sea.
An aerial view of a coastal town with a marina, buildings, and mountains in the background.
A hotel with a central courtyard, surrounded by lush greenery and a view of a lake with mountains in the background.

5. Porta Hotel del Lago

Porta Hotel del Lago
Panajachel
$122
$155 total
includes taxes & fees
Nov 18 - Nov 19
Porta Hotel del Lago
A resort with a pool, lounge chairs, and a mountainous backdrop.
A cozy interior with wooden beams, a chandelier, and a fireplace.
A bedroom with a large bed, a TV, a dresser, and a view of the sea.
An outdoor dining area with a view of the ocean and mountains, featuring rustic wooden beams, metal chairs, and a decorative wreath.

6. Hotel Atitlán

Hotel Atitlán
Panajachel
$244
$297 total
includes taxes & fees
Oct 21 - Oct 22
Hotel Atitlán
A hillside property with multiple buildings, including a prominent house with a spiral staircase and a smaller structure with a red roof.
A room with a large sliding glass door leading to an outdoor area, a bathtub, and a dining table.
A room with a bed, a hanging light fixture, and a wall tapestry.
A balcony with two wooden chairs, a small table with a vase, and a view of a lake and mountains.

7. Jenna's River Bed & Breakfast

Jenna's River Bed & Breakfast
Panajachel
$122
$148 total
includes taxes & fees
Oct 20 - Oct 21
Jenna's River Bed & Breakfast
A hotel room with two beds, a TV, a fireplace, and a wooden cabinet.
A traditional building with a tiled roof, surrounded by lush greenery and a well-maintained lawn.
A stone wall with a small waterfall, surrounded by lush tropical plants.
A bar area with wooden furniture, a checkered floor, and a bar counter with bottles.

8. Regis Hotel & Spa

Regis Hotel & Spa
Panajachel
$76
$98 total
includes taxes & fees
Oct 21 - Oct 22
Regis Hotel & Spa
A covered outdoor area with a view of a mountain and a body of water.
A hotel room with two beds, each with blue bedding and decorative headboards.
A corridor with tiled flooring, wooden doors, and hanging plants.
A building with a balcony, a wooden door, and a window with curtains.

9. Perla Maya Hotel

Perla Maya Hotel
Panajachel
$48
$59 total
includes taxes & fees
Oct 28 - Oct 29
Perla Maya Hotel
A pool area with a view of the sunset and mountains in the background.
A wedding ceremony on a grassy area with a backdrop of a calm lake and a mountain.
A hotel with a covered outdoor seating area, a garden with various plants, and a view of the sea.
A hotel with a view of the sea and mountains.

10. Hotel y Centro de Convenciones Jardines del Lago

Hotel y Centro de Convenciones Jardines del Lago
Panajachel
$102
$124 total
includes taxes & fees
Oct 23 - Oct 24
Hotel y Centro de Convenciones Jardines del Lago
Exterior
Property grounds
Interior
Room

11. Hotel Tzanjuyú Bay Historic

Hotel Tzanjuyú Bay Historic
Panajachel
$90
$110 total
includes taxes & fees
Oct 20 - Oct 21
Hotel Tzanjuyú Bay Historic
A pool area with lounge chairs and red umbrellas, surrounded by lush greenery and a view of a lake and mountains.
A bar with wooden shelves stocked with bottles and glasses, a bar counter, and a person preparing a drink.
A bedroom with a large bed, a wooden headboard, a bench, a window, and a door leading outside.
A pathway leading to a house surrounded by lush greenery and flowering plants.

12. Hotel Toliman

Hotel Toliman
San Lucas Toliman
$59
$82 total
includes taxes & fees
Oct 27 - Oct 28
Hotel Toliman
A patio with a round table and chairs, a view of a mountain and a lake.
A infinity pool with a view of a mountain range and a body of water.
A bedroom with a large bed, a nightstand, a lamp, and a view of the sea and mountains.
A cozy seating area with a bench and cushions, a fireplace, and colorful hanging lights.

13. Hotel Casa Palopó - Relais & Chateaux

Hotel Casa Palopó - Relais & Chateaux
Santa Catarina Palopo
$321
$424 total
includes taxes & fees
Oct 28 - Oct 29
Hotel Casa Palopó - Relais & Chateaux
A blue pool with a view of the sea and boats.
A view of a lake with mountains in the background, boats on the water, and a wooden deck in the foreground.
A wooden staircase with handrails, potted plants, and a view of the outside through a window.
A bedroom with a bed, a TV, and a view of the outdoors.

14. Posada de Don Rodrigo Panajachel

Posada de Don Rodrigo Panajachel
Panajachel
$176
$281 total
includes taxes & fees
Oct 20 - Oct 21
Posada de Don Rodrigo Panajachel
A large, multi-story house with a red roof, situated on a cliff overlooking a body of water.
An aerial view of a coastal property with multiple buildings, a dock with boats, and lush greenery.
A window with a view of a lake and a mountain.
A lush garden with a stone house and a view of the sea.

15. Hotel y Cafe La Casa del Mundo

Hotel y Cafe La Casa del Mundo
Santa Cruz La Laguna
$135
$165 total
includes taxes & fees
Nov 2 - Nov 3
Hotel y Cafe La Casa del Mundo
A dining table with a variety of breakfast items including pancakes, a bowl of fruit, and a plate with eggs and toast.
An outdoor bar area with wooden furniture, a Coca-Cola refrigerator, and a variety of bottles on the counter.
A hotel room with three beds, a wooden headboard, a TV mounted on the wall, and a window with curtains.
An outdoor bar area with wooden furniture and a thatched roof.

16. Hotel Panajachel Oasis

Hotel Panajachel Oasis
Panajachel
$58
$71 total
includes taxes & fees
Oct 20 - Oct 21
Hotel Panajachel Oasis
A multi-level outdoor patio with brick flooring, a wooden bench, and a staircase.
A multi-level residential building with a balcony, stairs, and a view of the surrounding landscape.
A compact kitchen with a built-in oven, a sink, and a stove. There is a wooden bench and a small table with a TV mounted above it.
A hotel room with two beds, a TV, and a small desk.

17. Hotel Posada don Miguel

Hotel Posada don Miguel
Panajachel
$33
$40 total
includes taxes & fees
Oct 21 - Oct 22
Hotel Posada don Miguel
A two-story building with balconies, potted plants, and outdoor seating.
A room with two beds, a nightstand, a wall-mounted lamp, and a framed picture.
A well-maintained garden with a lawn, a flowering bush, and a green building in the background.
A wooden staircase with black railings leading to a door.

18. Hotel Posada Kamol Bey

Hotel Posada Kamol Bey
Panajachel
$32
$39 total
includes taxes & fees
Oct 20 - Oct 21
Hotel Posada Kamol Bey
A pool area with stone flooring, lounge chairs, and a mountain backdrop.
A beach with colorful wire mesh chairs, a spherical sculpture, and umbrellas.
A wooden cabin with a bed, a small table, and a bench.
A beachside seating area with wooden tables and chairs, a thatched roof, and a view of the sea and mountains.

19. Socialtel Atitlan

Socialtel Atitlan
Panajachel
$59
$72 total
includes taxes & fees
Oct 20 - Oct 21
Socialtel Atitlan
A gazebo with a view of a lake and mountains during sunset.
A building with a stone foundation and a wooden upper structure.
A room with a bed, two chairs, a small table, and a view of the sea and mountains.
A garden with a view of a lake and mountains.

20. Hotel Hanna Suites

Hotel Hanna Suites
Panajachel
$38
$46 total
includes taxes & fees
Oct 29 - Oct 30
Hotel Hanna Suites
View all properties

Go beyond your typical stay in San Antonio Palopo

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Family friendly
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Our prices for hotels in San Antonio Palopo are cheapest in May

Price trends for hotels in San Antonio Palopo

Pricing is based on two traveler single night rates
View properties in October

October

High 28°C / low 19°C. Rainy most days.
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Learn more about San Antonio Palopo

The region around San Antonio Palopo is home to attractions such as Lake Atitlán and Casa Cakchiquel Arts Center.

See all hotels in San Antonio Palopo
A wooden pier extending into a calm sea with mountains in the background.

Check out reviews of San Antonio Palopo hotels guests love

A coastal property with multiple buildings, a dock, and a clear blue sea.
A round glass table with four chairs in a corner room with large windows.
A window with a view of mountains and a body of water.
A rustic room with a bed, a chair, and a table. There are large windows with a view of greenery outside.

Atitlan Oasis Eco Hotel and Spa Kaalpul

Atitlan Oasis Eco Hotel and Spa Kaalpul
San Antonio Palopo

10/10 Exceptional

United States
Erik
Atitlan Oasis Eco Hotel and Spa Kaalpul
A living room with a large sliding glass door leading to a balcony with a view of the sea and mountains.
A hotel room with a large bed, a balcony with a red railing, and a view of a lake and mountains.
A coastal property with a red-roofed building, a garden with various plants, and a view of the sea.
A cozy living room with a sofa, a coffee table, and a view of the sea through large windows.

Hotel La Villa de los Dioses

Hotel La Villa de los Dioses
San Antonio Palopo

10/10 Exceptional

United States
dixi
Hotel La Villa de los Dioses
A balcony with a view of a swimming pool, outdoor seating, and a mountainous landscape.
A dining area with tables set for a meal, overlooking a scenic view of a volcano and the sea.
An aerial view of a coastal town with a marina, buildings, and mountains in the background.
A hotel with a central courtyard, surrounded by lush greenery and a view of a lake with mountains in the background.

Porta Hotel del Lago

Porta Hotel del Lago
Panajachel

10/10 Exceptional

United States
Edwin
Porta Hotel del Lago
A resort with a swimming pool, a covered patio, and a view of the ocean and mountains.
A cozy living room with a fireplace, sofas, and a coffee table.
A balcony with a table and chairs, overlooking a scenic view of a lake and mountains.
A spacious bedroom with a large bed, wooden ceiling beams, and a view of the sea through an open door.

Hotel Villa Santa Catarina

Hotel Villa Santa Catarina
Santa Catarina Palopo

10/10 Exceptional

United States
Jose
Hotel Villa Santa Catarina
A hillside property with multiple buildings, including a prominent house with a spiral staircase and a smaller structure with a red roof.
A room with a large sliding glass door leading to an outdoor area, a bathtub, and a dining table.
A room with a bed, a hanging light fixture, and a wall tapestry.
A balcony with two wooden chairs, a small table with a vase, and a view of a lake and mountains.

Jenna's River Bed & Breakfast

Jenna's River Bed & Breakfast
Panajachel

10/10 Exceptional

United States
Leslie-Ann
Jenna's River Bed & Breakfast
A resort with a pool, lounge chairs, and a mountainous backdrop.
A cozy interior with wooden beams, a chandelier, and a fireplace.
A bedroom with a large bed, a TV, a dresser, and a view of the sea.
An outdoor dining area with a view of the ocean and mountains, featuring rustic wooden beams, metal chairs, and a decorative wreath.

Hotel Atitlán

Hotel Atitlán
Panajachel

10/10 Exceptional

United States
Liz
Hotel Atitlán
A patio with a round table and chairs, a view of a mountain and a lake.
A infinity pool with a view of a mountain range and a body of water.
A bedroom with a large bed, a nightstand, a lamp, and a view of the sea and mountains.
A cozy seating area with a bench and cushions, a fireplace, and colorful hanging lights.

Hotel Casa Palopó - Relais & Chateaux

Hotel Casa Palopó - Relais & Chateaux
Santa Catarina Palopo

10/10 Exceptional

United States
Edwin
Hotel Casa Palopó - Relais & Chateaux
A hotel room with two beds, a TV, a fireplace, and a wooden cabinet.
A traditional building with a tiled roof, surrounded by lush greenery and a well-maintained lawn.
A stone wall with a small waterfall, surrounded by lush tropical plants.
A bar area with wooden furniture, a checkered floor, and a bar counter with bottles.

Regis Hotel & Spa

Regis Hotel & Spa
Panajachel

10/10 Exceptional

United States
Jill
Regis Hotel & Spa
A large, multi-story house with a red roof, situated on a cliff overlooking a body of water.
An aerial view of a coastal property with multiple buildings, a dock with boats, and lush greenery.
A window with a view of a lake and a mountain.
A lush garden with a stone house and a view of the sea.

Hotel y Cafe La Casa del Mundo

Hotel y Cafe La Casa del Mundo
Santa Cruz La Laguna

10/10 Exceptional

United States
Mohammad
Hotel y Cafe La Casa del Mundo
A pool area with a view of the sunset and mountains in the background.
A wedding ceremony on a grassy area with a backdrop of a calm lake and a mountain.
A hotel with a covered outdoor seating area, a garden with various plants, and a view of the sea.
A hotel with a view of the sea and mountains.

Hotel y Centro de Convenciones Jardines del Lago

Hotel y Centro de Convenciones Jardines del Lago
Panajachel

10/10 Exceptional

United States
Juliana
Hotel y Centro de Convenciones Jardines del Lago
A table with a variety of food and drinks, including bread, cheese, and fruit, with a scenic view of a lake and mountains in the background.
A kitchen with a marble countertop, stainless steel sink, and hanging utensils.
A bedroom with a stone wall, a wooden ceiling, a bed with pillows, a chair, and a shelf with items.
A window with a view of a lake, trees, and a mountain.

El Picnic Atitlan

El Picnic Atitlan
Santa Cruz La Laguna

10/10 Exceptional

United States
deepti
El Picnic Atitlan
A blue pool with a view of the sea and boats.
A view of a lake with mountains in the background, boats on the water, and a wooden deck in the foreground.
A wooden staircase with handrails, potted plants, and a view of the outside through a window.
A bedroom with a bed, a TV, and a view of the outdoors.

Posada de Don Rodrigo Panajachel

Posada de Don Rodrigo Panajachel
Panajachel

10/10 Exceptional

United States
Carmen
Posada de Don Rodrigo Panajachel
A clear view of a lake with rocky shoreline and distant hills.
A bedroom with a bed, two bedside tables, a lamp on each table, and a window with curtains.
A calm lake with boats docked at a pier, surrounded by hills.
A bed with a blue quilt and white pillows, a rolled white towel, and yellow curtains.

Hotel Minnesota

Hotel Minnesota
San Lucas Tolimán

10/10 Exceptional

United States
Nelson
Hotel Minnesota
A two-story building with a balcony and a covered patio area.
A well-lit courtyard with a stone pathway, a parked car, and a small red-roofed structure.
A balcony with potted plants and a view of a mountainous landscape.
A room with two beds, a nightstand, a mirror, and a door.

Jabel Tinamit Hotel & Villas

Jabel Tinamit Hotel & Villas
Panajachel

10/10 Exceptional

United States
Clay
Jabel Tinamit Hotel & Villas
A luxurious resort with a large swimming pool, a well-lit outdoor area, and a canopy bed.
A wooden deck with potted plants and a view of a lake and a mountain.
A spacious room with large windows, a wooden ceiling, and a stone pillar.
A wooden pathway leading to a building with a sign reading "CASA PRANA BE WITH US."

Casa Prana Hotel In Atitlan

Casa Prana Hotel In Atitlan
Santa Cruz La Laguna

10/10 Exceptional

United States
Gabriela Soledad
Casa Prana Hotel In Atitlan
A multi-level outdoor patio with brick flooring, a wooden bench, and a staircase.
A multi-level residential building with a balcony, stairs, and a view of the surrounding landscape.
A compact kitchen with a built-in oven, a sink, and a stove. There is a wooden bench and a small table with a TV mounted above it.
A hotel room with two beds, a TV, and a small desk.

Hotel Posada don Miguel

Hotel Posada don Miguel
Panajachel

10/10 Exceptional

United States
Sonia
Hotel Posada don Miguel
A covered outdoor area with a view of a mountain and a body of water.
A hotel room with two beds, each with blue bedding and decorative headboards.
A corridor with tiled flooring, wooden doors, and hanging plants.
A building with a balcony, a wooden door, and a window with curtains.

Perla Maya Hotel

Perla Maya Hotel
Panajachel

10/10 Exceptional

United States
Yolanda
Perla Maya Hotel
A stone pathway flanked by lush green plants and hanging ferns.
A reception area with a wooden counter, a clock, and a bulletin board.
A hotel room with two beds, a wooden desk, a window with red curtains, and a decorative ceiling.
A corridor with hanging floral decorations and a central drainage grate.

Posada de Don Jose

Posada de Don Jose
Panajachel

10/10 Exceptional

United States
Azadeh
Posada de Don Jose
A resort with a pool, outdoor seating, and a view of the ocean and a mountain.
A tented accommodation with a bed, seating area, and large windows.
A resort with thatched-roof buildings, a pond with stepping stones, and lush greenery.
A stone-tiled bathroom with a wooden bench, hanging plants, and a stone sink.

Kula Maya Boutique Hotel & Spa

Kula Maya Boutique Hotel & Spa
San Marcos La Laguna

10/10 Exceptional

United States
Taneisha
Kula Maya Boutique Hotel & Spa

Frequently Asked Questions

What hotels do travelers like in San Antonio Palopo?

Guests like Atitlan Oasis Eco Hotel and Spa Kaalpul, Hotel La Villa de los Dioses and Porta Hotel del Lago.

Can I book a refundable hotel in San Antonio Palopo?

If you want the flexibility to change your plans to San Antonio Palopo, most hotels provide refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in San Antonio Palopo be like during my trip?

San Antonio Palopo is a great place to visit to enjoy the sunshine any time of year with an average temp of 74°F.

Why should I book my San Antonio Palopo hotel with Hotels.com?

There are lots of reasons to book your San Antonio Palopo trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.