Hotels in Sikeston
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Sep 3 - Sep 4Tomorrow
Sep 4 - Sep 5This weekend
Sep 4 - Sep 6Next weekend
Sep 11 - Sep 13Top 5 hotels in Sikeston at a glance
- Drury Inn & Suites Sikeston, MO — 3-star hotel in Sikeston. Guest rating: 9.6/10 — Exceptional.
- Holiday Inn Express & Suites Sikeston Southwest by IHG — 2.5-star hotel in Sikeston. Guest rating: 8.8/10 — Excellent.
- Hampton Inn Sikeston — 2.5-star hotel in Sikeston. Guest rating: 9.0/10 — Wonderful.
- Fairfield Inn & Suites by Marriott Sikeston — 3-star hotel in Sikeston. Guest rating: 9.4/10 — Exceptional.
- Best Western Plus Sikeston I-55 — 2.5-star hotel in Sikeston. Guest rating: 8.4/10 — Very Good.
Where to stay in Sikeston?
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
$94
$108 total
includes taxes & fees
Sep 14 - Sep 15
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
$105
$119 total
includes taxes & fees
Sep 13 - Sep 14
Hampton Inn Sikeston
Hampton Inn SikestonSikeston
$105
$119 total
includes taxes & fees
Oct 4 - Oct 5
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
$101
$114 total
includes taxes & fees
Sep 13 - Sep 14
Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
$93
$106 total
includes taxes & fees
Sep 8 - Sep 9
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
$66
$76 total
includes taxes & fees
Sep 7 - Sep 8
Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
$57
$65 total
includes taxes & fees
Sep 9 - Sep 10
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
$68
$78 total
includes taxes & fees
Sep 7 - Sep 8
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
$100
$113 total
includes taxes & fees
Sep 7 - Sep 8
TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
$118
$134 total
includes taxes & fees
Sep 13 - Sep 14
Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
$89
$101 total
includes taxes & fees
Sep 27 - Sep 28
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
$72
$81 total
includes taxes & fees
Sep 7 - Sep 8
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
$101
$115 total
includes taxes & fees
Sep 6 - Sep 7
Country Yard Inn and Suite
Country Yard Inn and SuiteSikeston
$59
$71 total
includes taxes & fees
Sep 16 - Sep 17
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
$80
$85 total
includes taxes & fees
Sep 7 - Sep 8
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
$101
$114 total
includes taxes & fees
Sep 10 - Sep 11
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
$106
$119 total
includes taxes & fees
Sep 13 - Sep 14
The Riverview
The RiverviewCape Girardeau
$114
$129 total
includes taxes & fees
Sep 8 - Sep 9
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
$125
$142 total
includes taxes & fees
Sep 13 - Sep 14
Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
$89
$102 total
includes taxes & fees
Sep 9 - Sep 10
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$111
per night
$255 total
includes taxes & fees
$106
per night
$240 total
includes taxes & fees
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
$123
per night
$279 total
includes taxes & fees
$118
per night
$267 total
includes taxes & fees
$89
per night
$203 total
includes taxes & fees
$131
per night
$297 total
includes taxes & fees
$68
per night
$155 total
includes taxes & fees
Sign in for extra savings
$59
per night
$134 total
includes taxes & fees
Sign in for extra savings
$98
per night
$223 total
includes taxes & fees
Sign in for extra savings
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
$73
per night
$168 total
includes taxes & fees
$61
per night
$146 total
includes taxes & fees
$106
per night
$238 total
includes taxes & fees
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
$195
per night
$441 total
includes taxes & fees
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
$141
per night
$318 total
includes taxes & fees
$134
per night
$302 total
includes taxes & fees
Check out pet-friendly hotels in Sikeston
$94
$108 total
includes taxes & fees
Sep 14 - Sep 15
$93
$106 total
includes taxes & fees
Sep 8 - Sep 9
$105
$119 total
includes taxes & fees
Oct 4 - Oct 5
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
$68
$78 total
includes taxes & fees
Sep 7 - Sep 8
$118
$134 total
includes taxes & fees
Sep 13 - Sep 14
$66
$76 total
includes taxes & fees
Sep 7 - Sep 8
$89
$101 total
includes taxes & fees
Sep 27 - Sep 28
$57
$65 total
includes taxes & fees
Sep 9 - Sep 10
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
$100
$113 total
includes taxes & fees
Sep 7 - Sep 8
$72
$81 total
includes taxes & fees
Sep 7 - Sep 8
You can also stay at hotels with a pool in Sikeston
$94
$108 total
includes taxes & fees
Sep 14 - Sep 15
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
$105
$119 total
includes taxes & fees
Sep 13 - Sep 14
$101
$114 total
includes taxes & fees
Sep 13 - Sep 14
$105
$119 total
includes taxes & fees
Oct 4 - Oct 5
$93
$106 total
includes taxes & fees
Sep 8 - Sep 9
$118
$134 total
includes taxes & fees
Sep 13 - Sep 14
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
$100
$113 total
includes taxes & fees
Sep 7 - Sep 8
$89
$101 total
includes taxes & fees
Sep 27 - Sep 28
$89
$102 total
includes taxes & fees
Sep 9 - Sep 10
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
$93
$100 total
includes taxes & fees
Sep 6 - Sep 7
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Sikeston
Pet friendly
Cottage
Family friendly
Our prices for hotels in Sikeston are cheapest in November
Our prices for hotels in Sikeston are cheapest in November
Price trends for hotels in Sikeston
Pricing is based on two traveler single night rates
Top landmarks in Sikeston
Sikeston Depot Museum
7.6/10 (57 reviews)
The center of Sikeston is home to cultural attractions like Sikeston Depot Museum, so you might want to stop by during your stay. If you want to experience more of the culture Sikeston has to offer, head to Central Park and City of Miner Convention Center.
Central Park
7.2/10 (56 reviews)
Central Park is 0.5 mi (0.8 km) from central Sikeston, why not stop by during your stay.
City of Miner Convention Center
City of Miner Convention Center is worth a visit when in central Miner.
Sikeston and related destinations
Catch a hot roll in mid-air at Lambert's Cafe, where servers hurl fresh bread across the dining room with remarkable accuracy. The historic downtown reveals a slice of small-town Americana, while the Sikeston Depot Museum chronicles the railroad heritage that put this place on the map. Central Park offers a leafy respite after exploring Front Street Studio & Art Gallery's local artwork. The City of Miner Convention Center hosts events that draw visitors from across the region. Positioned at the crossroads of major highways, this makes an ideal stopover between larger destinations, though locals insist you'll find reasons to linger beyond the flying carbs that made the town famous.
See all hotels in Sikeston
Check out reviews of Sikeston hotels guests love
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
10/10 Excellent
"Room was clean. Bed was a very comfortable best pillows We’ve had the whole trip . close to several different places to eat."
Pear Tree Inn Cape Girardeau West
10/10 Excellent
"Quick check in, Friendly Staff. AC was cold. Breakfast was good, preparer was friendly."
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
10/10 Excellent
"This location is a must stay any time I am traveling in the area. The staff are helpful. There are lots of dinning options near by. I can always count on a peaceful night sleep at this location."
Days Inn and Suites by Wyndham Sikeston
10/10 Excellent
"Front desk was welcoming and nice. Room was cleaned, beds were comfy. Very spacious. Quiet as well."
The Riverview
10/10 Excellent
"My stay was wonderful and the food was good"
Hampton Inn Sikeston
10/10 Excellent
"Very clean and very nice"