Top 10 Hotels in Salem, SC in 2026 (from $72)

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Where to stay in Salem?

A kitchen with a coffee maker, microwave, and refrigerator.

A hotel room with a large bed, a bedside table, a nightstand, and a wall-mounted lamp.

A hotel room with a bed, a desk with a chair, a television, a small table, and a microwave.

A reception area with a check-in desk, a seating area with a bench, and a wall-mounted display of postcards.

1. Rodeway Inn & Suites Walhalla

Walhalla

$72

$81 total

includes taxes & fees

Nov 15 - Nov 16

A poolside area with outdoor seating and a view of a lake and forested hills.

A modern lobby with a reception desk, seating area, and a vending machine.

A modern lounge area with a round table, two green armchairs, a sofa, and a TV mounted on the wall.

A modern cafe interior with round tables and chairs, a counter with a beverage dispenser, and a wall-mounted TV.

2. Fairfield Inn & Suites Seneca Clemson Univ Area

Seneca

$120

$132 total

includes taxes & fees

Nov 1 - Nov 2

A hotel dining area with a long table, multiple chairs, and a bar in the background.

A long, narrow hallway with white walls and a light-colored floor, leading to a door at the end.

A hotel pantry with shelves stocked with snacks, a microwave, and a refrigerator with beverages.

A Hampton Inn & Suites hotel with a well-lit entrance, a parking lot, and a clear view of the building's exterior.

3. Hampton Inn & Suites Seneca-Clemson Area

Seneca

$119

$131 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

A breakfast bar with waffle makers, coffee machines, and a clock on the wall.

A reception area with a brick wall, a reception desk, and a glass door leading outside.

A rectangular swimming pool with a metal ladder, surrounded by lounge chairs and tables, with a wooded area in the background.

4. Best Western Seneca-Clemson

Seneca

$102

$112 total

includes taxes & fees

Oct 28 - Oct 29

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

A multi-story motel with a central entrance, a flag, and a parking lot with several cars.

A hotel room with a TV on a wooden cabinet, a desk with a lamp, a framed picture, and a chair.

A hotel room with a bed, desk, TV, and a bathroom visible through an open door.

5. Quality Inn Seneca US-123

Seneca

$78

$92 total

includes taxes & fees

Oct 18 - Oct 19

A modern dining area with a high ceiling, large windows, and a buffet setup.

A swimming pool with lounge chairs and a fence, surrounded by trees.

A modern hotel lobby with a high ceiling, comfortable seating, large windows, and a view of the parking lot.

A modern hotel room with a large bed, bedside tables with lamps, a wall-mounted air conditioner, and a large window with curtains.

6. Days Inn by Wyndham Seneca / Clemson Area

Seneca

$85

$94 total

includes taxes & fees

Oct 19 - Oct 20

A wooden interior with a fireplace, large windows, and outdoor deck.

A bedroom with a bed, a desk, a chair, a window, and a door.

A lodge with a wooden exterior, a balcony, and a staircase leading to the upper level.

A rustic wooden dining area with a large table and chairs, large windows with a forest view, and a fireplace.

7. Brook Trout Inn

Sapphire

$164

$183 total

includes taxes & fees

Oct 18 - Oct 19

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

An aerial view of a multi-story hotel with a central courtyard, outdoor pool, and lounge area.

A spacious dining area with a long wooden table and patterned upholstered chairs.

A swimming pool with lounge chairs and a covered patio area, surrounded by trees and a view of a lake.

8. Lakeside Lodge Clemson

Seneca

$109

$135 total

includes taxes & fees

Oct 18 - Oct 19

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

A wall with a decorative design featuring a building, trees, and a sky with clouds.

A hotel room with two beds, a desk, a television, and a clock on the wall.

A dining area with a brick floor, wooden tables, and chairs, a kitchen counter with appliances, and large windows offering a view of the outside.

9. Inn @ Clemson

Clemson

$89

$99 total

includes taxes & fees

Oct 18 - Oct 19

A modern bar area with a menu board, bar stools, and a countertop with various items.

An outdoor patio with a circular fire pit surrounded by wicker furniture and a pergola overhead.

A modern lobby with a reception desk, a seating area with three chairs, a round table, and a bookshelf with books.

A modern dining area with a bar, bar stools, and a patterned rug.

10. Courtyard Marriott Clemson

Clemson

$111

$123 total

includes taxes & fees

Oct 18 - Oct 19

An outdoor patio area with a fire pit, seating, and string lights.

A food court with a beverage display, seating area, and a Clemson University sign.

A modern restaurant with a central counter, seating area, and a TV displaying news.

A modern indoor space with a mix of seating options, including a sofa and tables, under stylish pendant lighting.

11. Tru by Hilton Seneca Clemson

Seneca

$110

$121 total

includes taxes & fees

Nov 8 - Nov 9

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.

A bar area with a counter, multiple chairs, and a display of bottles and glasses.

A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.

12. The Abernathy of Clemson

Clemson

$170

$189 total

includes taxes & fees

Nov 1 - Nov 2

A wooden deck with a camera on a tripod, overlooking a mountainous landscape with lush greenery.

A modern hotel room with a large bed, a flat-screen TV, a seating area with a table and bench, and a window offering a view of trees.

A spacious living area with a stone fireplace, high ceilings, and large windows.

A large indoor swimming pool with clear lanes, a lifeguard station, and multiple seating areas.

13. Hampton Inn & Suites Cashiers Sapphire Valley

Sapphire

$127

$143 total

includes taxes & fees

Nov 8 - Nov 9

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

A modern bar area with a wooden ceiling, green bar stools, and a bar counter.

A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

An outdoor patio with wicker furniture, a round table, and a fountain.

14. The Shepherd Hotel Downtown Clemson

Clemson

$209

$232 total

includes taxes & fees

Oct 18 - Oct 19

A swimming pool with lounge chairs and a covered area with tables and chairs.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a microwave.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

15. Carolina Camp Cedar

Pickens

$109

$204 total

includes taxes & fees

Oct 18 - Oct 19

A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

A hotel breakfast area with a self-serve station, including a refrigerator, coffee machine, and fruit display.

A conference room with a large round table, multiple chairs, and a projector.

A hotel room with a large bed, bedside tables, a desk with a chair, a TV, and a window with a view.

16. Holiday Inn Express & Suites Clemson by IHG

Clemson

$129

$143 total

includes taxes & fees

Oct 18 - Oct 19

A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

A brick building with a sign reading "The Inn at Patrick Square".

A hotel with a brick facade, multiple windows, and a sign reading "The Inn at Patrick Square".

A modern restaurant with a marble-top dining table, blue upholstered chairs, and a variety of food items displayed in the background.

17. The Inn at Patrick Square

Clemson

$149

$165 total

includes taxes & fees

Oct 18 - Oct 19

A forested area with a fire pit and wooden chairs.

A spacious living area with a large window, a wooden dining table, and a cozy seating arrangement.

A room with a desk, two chairs, a small table with a vase of flowers, and a view of greenery outside.

18. Trailborn Highlands, Outdoor Collection by Marriott Bonvoy

Highlands

$169

$185 total

includes taxes & fees

Nov 15 - Nov 16

A golf course with a water body, trees, and a distant view of a bridge.

A modern building with a central entrance, surrounded by a well-maintained lawn and trees.

A large, curved swimming pool with lounge chairs and umbrellas, surrounded by landscaped areas and a building in the background.

A golf course with a clubhouse, surrounded by dense trees and a large body of water.

19. Clemson University's James F. Martin Inn

Clemson

$149

$165 total

includes taxes & fees

Oct 18 - Oct 19

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A cozy living room with a dining table, sofas, and a chandelier.

A bedroom with a bed, bedside tables, a nightstand, a wooden floor, a door, and a wall-mounted shelf.

20. Clemson Memorabilia House

Clemson

$89

$238 total

includes taxes & fees

Oct 18 - Oct 19

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Go beyond your typical stay in Salem

Top neighborhoods in Salem

Turtlehead

Turtlehead

Salem's Turtlehead neighborhood is home to attractions such as Lake Keowee and Chapman Bridge Oconee Bell Preserve.

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Top landmarks in Salem

Devils Fork State Park

9.2/10 (41 reviews)

Devils Fork State Park is 4.7 mi (7.5 km) from central Salem, why not stop by during your stay.

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Keowee Key Golf Course

9.6/10 (7 reviews)

You might want to practice your swing at Keowee Key Golf Course, a golf course located 4.9 mi (7.9 km) from central Salem. If Keowee Key Golf Course doesn't quite scratch your golfing itch, Keowee Springs Golf Course is also nearby.

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Devils Fork Lake Jocassee

Devils Fork Lake Jocassee is 4.6 mi (7.4 km) from central Salem, why not stop by during your stay. If you like Devils Fork Lake Jocassee, you'll love Long Shoals Recreation Area and DAR Monument, both just a short drive away.

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South Beach

If want to top up your tan, you might want to head out to South Beach, located 6 mi (9.7 km) from central Salem. Enjoy the sunset by the shore at North Beach.

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Keowee Key Fitness & Tennis Center

You can catch an event at Keowee Key Fitness & Tennis Center, located 4.7 mi (7.6 km) from central Salem.

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Ultimate Action Sports

10.0/10 (1 review)

Ultimate Action Sports is 2.5 mi (4.1 km) from central Salem, why not stop by during your stay. If you'd also like to explore some of the parks in Salem, Devils Fork Lake Jocassee and DAR Monument are both nearby.

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North Beach

If being by the water is a major draw, North Beach is a spot you might want to check out, located 5.1 mi (8.1 km) from central Salem. Enjoy the sunset by the shore at South Beach.

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Chapman Bridge Oconee Bell Preserve

Chapman Bridge Oconee Bell Preserve is 4 mi (6.4 km) from central Salem, why not stop by during your stay.

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Learn more about Salem

Salem is well-known for its attractions such as Devils Fork Lake Jocassee and Devils Fork State Park.

See all hotels in Salem

Check out reviews of Salem hotels guests love

Hampton Inn & Suites Seneca-Clemson Area

Seneca

10/10 Exceptional

LuAnn

The Shepherd Hotel Downtown Clemson

Clemson

10/10 Exceptional

Amy

The Inn at Patrick Square

Clemson

10/10 Exceptional

SHARRA

Brook Trout Inn

Sapphire

10/10 Exceptional

Julie

The Abernathy of Clemson

Clemson

10/10 Exceptional

Michele

A hotel with a stone facade, large windows, and a well-maintained garden.

A person holding a dog in a garden with various plants and a street lamp.

A living room with a grey sofa, a dining table, a lamp, and a kitchen area with a dishwasher.

A bedroom with a large bed, a dark-colored bench, a patterned carpet, and a view of the outside through a glass door.

The Park On Main

Downtown Highlands

10/10 Exceptional

Jim

Lakeside Lodge Clemson

Seneca

10/10 Exceptional

Maria

Trailborn Highlands, Outdoor Collection by Marriott Bonvoy

Highlands

10/10 Exceptional

Jennifer

Best Western Seneca-Clemson

Seneca

10/10 Exceptional

Amy

Courtyard Marriott Clemson

Clemson

10/10 Exceptional

Anonymous traveler

Clemson University's James F. Martin Inn

Clemson

10/10 Exceptional

Margot

Hampton Inn & Suites Cashiers Sapphire Valley

Sapphire

10/10 Exceptional

Anonymous traveler

A white, two-story house with a front porch, surrounded by trees and shrubs.

A dining area with round tables, black chairs, and white tablecloths.

A bedroom with two beds, a TV, and a fireplace.

A hallway with a wooden bench, a chair, a cabinet, and a painting on the wall.

Liberty Hall Bed and Breakfast

Pendleton

10/10 Exceptional

William

A modern living room with a stone fireplace, wooden flooring, and black leather furniture.

A log cabin with a porch, surrounded by trees.

A dining area with a wooden table and chairs, a kitchen with white cabinets, and a bedroom with a bed and nightstand.

A bedroom with a large bed, wooden ceiling beams, a ceiling fan, a TV mounted on the wall, and a balcony with a view of trees.

The Wells Hotel Cashiers

Cashiers

10/10 Exceptional

Norman

Frequently Asked Questions

Can I book refundable accommodations in Salem?

If you want the flexibility to change your travel plans to Salem, most properties provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Salem if I want a vacation rental instead of a hotel?

If you want to find a good alternative to a hotel, browse our selection of 42 vacation homes. In addition, there are 25 apartments and 51 condos.

What will the weather in Salem be like during my trip?

The warmest months in Salem are usually July and August with an average temp of 68°F. January and February are the chilliest months when the average temp is 42°F. The rainiest months are December and April.

Why should I book my Salem hotel through Hotels.com?

There are plenty of reasons to book your Salem travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.