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Hotels in De Soto

September 2026
13
October 2026

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Next weekend
Sep 18 - Sep 20
In two weeks
Sep 25 - Sep 27

Where to stay in De Soto?

A modern kitchen with a central island, built-in appliances, and a view into the dining area.
A swimming pool area with a clear pool, a lifeguard chair, and a sign indicating the pool's depth.
A reception desk with a modern design, a digital screen, and a sign indicating 'IHG' branding.
A hotel room with a bed, a desk, a microwave, a coffee maker, and a TV mounted on the wall.

1. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Festus
$103
$118 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.
A swimming pool with lounge chairs and a view of the night sky.
A modern hotel with a prominent 'La Quinta' sign, large windows, and a well-lit entrance.
A hotel room with a large bed, a bedside table with a lamp, a vanity with a mirror, and a wall with framed pictures.

2. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Festus
$84
$96 total
includes taxes & fees
Sep 16 - Sep 17
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
A hotel room with a bed, bedside tables, a desk, a chair, a lamp, and a window.

3. Hampton Inn & Suites By Hilton Festus

Hampton Inn & Suites By Hilton Festus
Festus
$94
$108 total
includes taxes & fees
Oct 8 - Oct 9
Hampton Inn & Suites By Hilton Festus
A laundry room with two washing machines, a change machine, and a chair.
An indoor swimming pool with a tiled edge, surrounded by lounge chairs and a potted plant.
A breakfast corner with a waffle maker, coffee machines, and a sign for breakfast.
A hotel room with two beds, a desk with a TV, a chair, and a window with curtains.

4. Baymont by Wyndham Festus

Baymont by Wyndham Festus
Festus
$69
$79 total
includes taxes & fees
Sep 20 - Sep 21
Baymont by Wyndham Festus
A hotel lobby with a reception desk, two red armchairs, a floral centerpiece, a framed cityscape picture, and a dining area in the background.
A hotel lobby with a seating area, a reception desk, and a dining area.
A hotel lobby with a reception desk, two red armchairs, a coffee table, a floral centerpiece, and a dining area with wooden tables and chairs.
A hotel room with a shower, a bathtub, a toilet, a bed, a desk, a chair, and a television.

5. Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
Festus
$75
$88 total
includes taxes & fees
Oct 11 - Oct 12
Comfort Inn Festus - St Louis South
A hotel lobby with a reception desk, a revolving door, seating area with sofas, and a patterned rug.
A conference room with round tables and chairs, a patterned carpet, and a chandelier.
A modern living room with a sectional sofa, a glass coffee table, and a fireplace.
A hotel room with two beds, a nightstand, a lamp, and a painting on the wall.

6. Days Inn & Suites By Wyndham Festus

Days Inn & Suites By Wyndham Festus
Festus
$75
$86 total
includes taxes & fees
Sep 14 - Sep 15
Days Inn & Suites By Wyndham Festus

7. Super 8 by Wyndham Pevely

Super 8 by Wyndham Pevely
Pevely
$71
$82 total
includes taxes & fees
Sep 20 - Sep 21
Super 8 by Wyndham Pevely
A cabin with a large window, surrounded by trees.

8. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
French Village
$93
$151 total
includes taxes & fees
Sep 17 - Sep 18
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
A modern hotel room with a large bed, a desk with a lamp, a TV, and a wardrobe.
A modern kitchen with a black microwave, a refrigerator, and a flat-screen TV mounted above a desk with a yellow lamp.
A reception area with a large number '6' sign, a modern counter, and a colorful striped wall.
A motel with a prominent '6' sign, a well-lit entrance, and a visible parking area.

9. Motel 6 Bonne Terre, MO

Motel 6 Bonne Terre, MO
Bonne Terre
$61
$72 total
includes taxes & fees
Sep 20 - Sep 21
Motel 6 Bonne Terre, MO
A double door with horizontal slats, flanked by two windows with white frames.
A bed with a headboard, pillows, and a blanket in a room with plain walls.
A modern kitchen with dark blue cabinets, a large window with a view of greenery, and a built-in oven.
A modern living room with a sofa, coffee table, and a TV mounted on the wall.

10. Vive mol

Vive mol
BONNE TERRE
$108
$158 total
includes taxes & fees
Sep 14 - Sep 15
Vive mol
An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.
A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A modern bathroom with a bathtub, a window with curtains, and a view of a green landscape.

11. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
Farmington
$110
$119 total
includes taxes & fees
Sep 14 - Sep 15
Crown Pointe Lodge, BW Signature Collection
A stone building with a white porch and a small garden with yellow flowers.
A cozy seating area with wicker chairs and a coffee table, a brick wall, and a window with a view of greenery.
A narrow stone pathway leading to a brick house with a dark wooden door and a window with a white frame.
A vintage upright piano with a mirror above it, a lamp, and a floral wallpaper pattern.

12. Corner George Inn Bed & Breakfast

Corner George Inn Bed & Breakfast
Maeystown
$129
$143 total
includes taxes & fees
Sep 15 - Sep 16
Corner George Inn Bed & Breakfast
A lobby with a reception desk, blue sofas, a coffee table, and a plant display.
An indoor swimming pool area with a hot tub, a table with chairs, and a sign warning of no lifeguard on duty.
A spacious dining area with multiple tables and chairs, large windows, and ceiling lights.
A hotel room with a TV, a sofa, a small table, a lamp, and a carpeted floor.

13. Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
Arnold
$126
$146 total
includes taxes & fees
Sep 20 - Sep 21
Drury Inn & Suites St. Louis Arnold
A hotel room with a bed, a sofa, a desk, and a chair.
A modern living room with a sofa, armchairs, a coffee table, and a painting on the wall.
An indoor swimming pool with a tiled edge, surrounded by lounge chairs and potted plants.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

14. Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
Farmington
$110
$120 total
includes taxes & fees
Sep 20 - Sep 21
Holiday Inn Express & Suites Farmington by IHG
A modern interior with a high ceiling, large windows, and a brick wall. There are orange chairs and a green sofa with orange cushions.
A modern indoor space with a large window, a seating area with sofas and chairs, and a dining area with tables and chairs.
A modern building with a prominent entrance, large windows, and a covered parking area.
A hotel room with a bed, a desk, a television, a sofa, and a lamp.

15. Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
Arnold
$90
$104 total
includes taxes & fees
Sep 20 - Sep 21
Pear Tree Inn St. Louis Arnold
A hotel room with a large bed, two bedside tables, a nightstand, and a framed picture on the wall.
A modern waiting area with a grey sofa, a small table, and a black office chair. There are two doors with signs indicating restrooms.
An indoor swimming pool with clear lanes, a sunlit room with a view, and a staircase leading to an upper level.
A hotel reception area with a green carpet, a reception desk, a seating area with chairs, and a poster advertising the hotel.

16. Quality Inn Farmington

Quality Inn Farmington
Farmington
$59
$67 total
includes taxes & fees
Sep 20 - Sep 21
Quality Inn Farmington
A living room with a sofa, coffee table, and a small table with a vase. There is a window with blinds and a door in the background.
A hotel room with a bed, a desk, a chair, a couch, and a TV.
An indoor swimming pool with a 3 FT depth marker, surrounded by white walls and a ceiling with recessed lighting.
A reception area with a green marble counter, framed certificates on the wall, and a clock.

17. Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
Bonne Terre
$64
$70 total
includes taxes & fees
Sep 14 - Sep 15
Super 8 by Wyndham Bonne Terre
A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.
A hotel room with a large bed, two sofas, a desk with a lamp, a microwave, and a TV.
A hotel reception area with a glass partition, a reception desk, and a digital kiosk.

18. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
$57
$62 total
includes taxes & fees
Sep 20 - Sep 21
Baymont Inn and Suites by Wyndham Farmington, MO
A wooden deck with two Adirondack chairs and a hammock.
A spacious living room with a wooden ceiling, a fireplace, and a television.
A bedroom with a large bed, wooden ceiling, and a view of the outdoors.
A spacious living room with wooden floors, a stone fireplace, and a mounted television.

19. Tiny Houses of French Village

Tiny Houses of French Village
French Village
$222
$339 total
includes taxes & fees
Sep 14 - Sep 15
Tiny Houses of French Village
A large, two-story house with a wrap-around porch and a central tower.
A covered patio with a picnic table, surrounded by a brick pathway and greenery.
A room with a red velvet sofa, a chandelier, a mirror, and a vanity with a sink.
A dining room with a wooden table set for four, surrounded by upholstered chairs. A large wooden cabinet with intricate carvings is positioned against the wall.

20. The Conner House B&B

The Conner House B&B
Prairie du Rocher
$156
$173 total
includes taxes & fees
Sep 14 - Sep 15
The Conner House B&B
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Go beyond your typical stay in De Soto

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Our prices for hotels in De Soto are cheapest in July

Price trends for hotels in De Soto

Pricing is based on two traveler single night rates
View properties in September

September

High 28°C / low 16°C. Sunny most days.
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Monthly weather averages (˚C)

Top landmarks in De Soto

Sunrise Lake Beach

If being by the water is a major draw, Sunrise Lake Beach is a spot you might want to check out, located 6.4 mi (10.3 km) from central De Soto.
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Valle Lake Beach

Valle Lake Beach is 6.4 mi (10.3 km) from central De Soto, why not stop by during your stay. Want to stretch your legs some more? Head to Sunrise Lake Park, located nearby.
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Big Lake

Big Lake is 7 mi (11.3 km) from central De Soto, why not stop by during your stay.
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Clear Lake

Clear Lake is 6.1 mi (9.8 km) from central De Soto, why not stop by during your stay.
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Joachim Park

Joachim Park is worth a visit, located 0.4 mi (0.7 km) from central De Soto.
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Victoria Glaces Conservation Area Trailhead

6.0/10 (1 review)
Victoria Glaces Conservation Area Trailhead is 4.4 mi (7.1 km) from central De Soto, why not stop by during your stay.
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Sunrise Lake

Sunrise Lake is 6.4 mi (10.3 km) from central De Soto, why not stop by during your stay.
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Eastside Community Park

Eastside Community Park is worth a visit, located 0.7 mi (1.1 km) from central De Soto.
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Learn more about De Soto

De Soto is well-known for its attractions such as Washington State Park and Big River.

See all hotels in De Soto
A blue kayak on calm river water with trees and rocky cliffs in the background.
Photo by Jessica King

Check out reviews of De Soto hotels guests love

A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.
A swimming pool with lounge chairs and a view of the night sky.
A modern hotel with a prominent 'La Quinta' sign, large windows, and a well-lit entrance.
A hotel room with a large bed, a bedside table with a lamp, a vanity with a mirror, and a wall with framed pictures.

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Festus

10/10 Exceptional

United States
Adrian
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
A lobby with a reception desk, blue sofas, a coffee table, and a plant display.
An indoor swimming pool area with a hot tub, a table with chairs, and a sign warning of no lifeguard on duty.
A spacious dining area with multiple tables and chairs, large windows, and ceiling lights.
A hotel room with a TV, a sofa, a small table, a lamp, and a carpeted floor.

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
Arnold

10/10 Exceptional

United States
Rachel
Drury Inn & Suites St. Louis Arnold
A modern interior with a high ceiling, large windows, and a brick wall. There are orange chairs and a green sofa with orange cushions.
A modern indoor space with a large window, a seating area with sofas and chairs, and a dining area with tables and chairs.
A modern building with a prominent entrance, large windows, and a covered parking area.
A hotel room with a bed, a desk, a television, a sofa, and a lamp.

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
Arnold

10/10 Exceptional

United States
Blaine
Pear Tree Inn St. Louis Arnold
An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.
A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A modern bathroom with a bathtub, a window with curtains, and a view of a green landscape.

Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
Farmington

10/10 Exceptional

United States
Scott
Crown Pointe Lodge, BW Signature Collection
A hotel room with a large bed, two bedside tables, a nightstand, and a framed picture on the wall.
A modern waiting area with a grey sofa, a small table, and a black office chair. There are two doors with signs indicating restrooms.
An indoor swimming pool with clear lanes, a sunlit room with a view, and a staircase leading to an upper level.
A hotel reception area with a green carpet, a reception desk, a seating area with chairs, and a poster advertising the hotel.

Quality Inn Farmington

Quality Inn Farmington
Farmington

10/10 Exceptional

United States
ebonee
Quality Inn Farmington
A modern kitchen with a central island, built-in appliances, and a view into the dining area.
A swimming pool area with a clear pool, a lifeguard chair, and a sign indicating the pool's depth.
A reception desk with a modern design, a digital screen, and a sign indicating 'IHG' branding.
A hotel room with a bed, a desk, a microwave, a coffee maker, and a TV mounted on the wall.

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Festus

10/10 Exceptional

United States
Anonymous traveler
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
A bedroom with a large window, a bed, a wooden chair, and a table.
A view through a window of a lake, trees, and a building.
A wooden cabin with large windows, a view of a lake, and a forested hillside.
A hotel room with two beds, a desk, and a view of the outdoors.

YMCA Trout Lodge

YMCA Trout Lodge
Potosi

10/10 Exceptional

United States
Timothy
YMCA Trout Lodge
A hotel lobby with a reception desk, two red armchairs, a floral centerpiece, a framed cityscape picture, and a dining area in the background.
A hotel lobby with a seating area, a reception desk, and a dining area.
A hotel lobby with a reception desk, two red armchairs, a coffee table, a floral centerpiece, and a dining area with wooden tables and chairs.
A hotel room with a shower, a bathtub, a toilet, a bed, a desk, a chair, and a television.

Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
Festus

10/10 Exceptional

United States
CindyLucy
Comfort Inn Festus - St Louis South
A hotel room with a bed, bedside tables, a desk, a chair, a lamp, and a window.

Hampton Inn & Suites By Hilton Festus

Hampton Inn & Suites By Hilton Festus
Festus

10/10 Exceptional

United States
Yvelises
Hampton Inn & Suites By Hilton Festus
A cabin with a large window, surrounded by trees.

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
French Village

10/10 Exceptional

United States
Lisa
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
A wooden deck with two Adirondack chairs and a hammock.
A spacious living room with a wooden ceiling, a fireplace, and a television.
A bedroom with a large bed, wooden ceiling, and a view of the outdoors.
A spacious living room with wooden floors, a stone fireplace, and a mounted television.

Tiny Houses of French Village

Tiny Houses of French Village
French Village

10/10 Exceptional

United States
Chris
Tiny Houses of French Village
A large, two-story house with a wrap-around porch and a central tower.
A covered patio with a picnic table, surrounded by a brick pathway and greenery.
A room with a red velvet sofa, a chandelier, a mirror, and a vanity with a sink.
A dining room with a wooden table set for four, surrounded by upholstered chairs. A large wooden cabinet with intricate carvings is positioned against the wall.

The Conner House B&B

The Conner House B&B
Prairie du Rocher

10/10 Exceptional

United States
Anonymous traveler
The Conner House B&B
A stone building with a white porch and a small garden with yellow flowers.
A cozy seating area with wicker chairs and a coffee table, a brick wall, and a window with a view of greenery.
A narrow stone pathway leading to a brick house with a dark wooden door and a window with a white frame.
A vintage upright piano with a mirror above it, a lamp, and a floral wallpaper pattern.

Corner George Inn Bed & Breakfast

Corner George Inn Bed & Breakfast
Maeystown

10/10 Exceptional

United States
Richard
Corner George Inn Bed & Breakfast
A living room with a sofa, coffee table, and a small table with a vase. There is a window with blinds and a door in the background.
A hotel room with a bed, a desk, a chair, a couch, and a TV.
An indoor swimming pool with a 3 FT depth marker, surrounded by white walls and a ceiling with recessed lighting.
A reception area with a green marble counter, framed certificates on the wall, and a clock.

Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
Bonne Terre

10/10 Exceptional

United States
William
Super 8 by Wyndham Bonne Terre
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A reception area with a wooden counter, a desk, and a computer.
A motel with a covered parking area, a brick facade, and a sign indicating it is number 8.
A laundry area with two washing machines and a dryer.

Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi
Potosi

10/10 Exceptional

United States
Anonymous traveler
Super 8 by Wyndham Potosi
A modern kitchen with a coffee machine, a refrigerator, and a microwave.
A laundry room with a front-loading washer and dryer, a door, and a light fixture.
A hotel room with a large bed, a smaller bed, a nightstand with a lamp, and two large framed pictures on the wall.
A hotel lobby with a reception desk, a blue armchair, a wall-mounted clock, and a framed welcome sign.

Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
Farmington

10/10 Exceptional

United States
MarBella
Super 8 by Wyndham Farmington

Frequently Asked Questions

What accommodations do travelers recommend in De Soto?

Guests like Comfort Inn Festus - St Louis South, La Quinta Inn & Suites by Wyndham Festus - St. Louis South and Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG.

Can I book a refundable hotel in De Soto?

If you're looking for the flexibility to change your plans to De Soto, most hotels provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in De Soto be like during my trip?

July and August are typically the warmest months in De Soto when the average temp is 75°F. January and February are the coldest months when the average temperature is 38°F. April and May are the months with the most rain.

Why should I book my De Soto hotel through Hotels.com?

There are lots of reasons to book your De Soto trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.