Hotels in St. Charles

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Relax Inn Saint Charles
Relax Inn Saint Charles
2.0 star property
St. Charles
6.8 out of 10, (1,001 reviews)
  • cleanliness
    Affordable highway motel with 24-hour service just minutes from Ameristar Casino.
The price is $63
$72 total
includes taxes & fees
Mar 13 - Mar 14
Relax Inn Saint Charles
Super 8 by Wyndham St Charles
Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.0 out of 10, Very Good, (1,008 reviews)
  • cleanliness
    Peaceful highway oasis with free continental breakfast and casino access nearby.
The price is $84
$97 total
includes taxes & fees
Mar 19 - Mar 20
Super 8 by Wyndham St Charles
WoodSpring Suites St Louis St Charles
WoodSpring Suites St Louis St Charles
2.5 star property
St. Charles
5.4 out of 10, (293 reviews)
  • cleanliness
    Convenient home base near Ameristar Casino with free WiFi and parking.
The price is $80
$92 total
includes taxes & fees
Mar 30 - Mar 31
WoodSpring Suites St Louis St Charles
Holiday Inn Express Hotel and Suites St. Charles by IHG
Holiday Inn Express Hotel and Suites St. Charles by IHG
3.0 star property
St. Charles
8.2 out of 10, Very Good, (722 reviews)
  • cleanliness
    Ideal getaway with free breakfast near Ameristar Casino and Hollywood Casino.
The price is $139
$160 total
includes taxes & fees
Mar 22 - Mar 23
Holiday Inn Express Hotel and Suites St. Charles by IHG
Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. Charles
3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    Retreat with indoor and outdoor pools near Ameristar Casino in St. Charles.
The price is $144
$167 total
includes taxes & fees
Apr 3 - Apr 4
Drury Plaza Hotel St. Louis St. Charles
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
St. Charles
5.8 out of 10, (1,005 reviews)
  • cleanliness
    Experience the best of St. Charles with easy access to Ameristar Casino nearby.
The price is $90
$104 total
includes taxes & fees
Mar 15 - Mar 16
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1,000 reviews)
  • cleanliness
    Serene pool and fitness amenities near Ameristar Casino in convenient St. Charles.
The price is $106
$122 total
includes taxes & fees
Mar 29 - Mar 30
Hampton Inn St. Charles St. Peters
Sleep Inn Saint Charles North
Sleep Inn Saint Charles North
2.5 star property
St. Charles
5.8 out of 10, (524 reviews)
  • cleanliness
    Modern comfort just minutes from Ameristar Casino with free breakfast and parking.
The price is $68
$79 total
includes taxes & fees
Apr 5 - Apr 6
Sleep Inn Saint Charles North
Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very Good, (1,009 reviews)
  • cleanliness
    Riverside comfort with easy casino access and complimentary breakfast each morning.
The price is $84
$97 total
includes taxes & fees
Apr 5 - Apr 6
Comfort Suites St Charles - St Louis
Country Inn & Suites by Radisson, St. Peters, MO
Country Inn & Suites by Radisson, St. Peters, MO
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1,000 reviews)
  • cleanliness
    Stay near Ameristar Casino in St. Charles with indoor pool and free amenities.
The price is $85
$97 total
includes taxes & fees
Apr 5 - Apr 6
Country Inn & Suites by Radisson, St. Peters, MO
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1,000 reviews)
  • cleanliness
    Luxurious casino resort with spa treatments and poolside relaxation in St. Charles.
The price is $170
$215 total
includes taxes & fees
Apr 5 - Apr 6
Ameristar Casino Resort and Spa
Candlewood Suites St Louis St Charles by IHG
Candlewood Suites St Louis St Charles by IHG
2.5 star property
St. Charles
7.6 out of 10, Good, (786 reviews)
  • cleanliness
    Guests praise the central location, just minutes from top St. Charles attractions.
The price is $84
$97 total
includes taxes & fees
Mar 15 - Mar 16
Candlewood Suites St Louis St Charles by IHG
Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Stay just 5 minutes from Ameristar Casino in this business-friendly hotel.
The price is $122
$140 total
includes taxes & fees
Apr 5 - Apr 6
Embassy Suites by Hilton St. Louis St. Charles
Hampton Inn & Suites St. Charles Old Town Area
Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
St. Charles
9.0 out of 10, Wonderful, (663 reviews)
  • cleanliness
    Riverside retreat in St. Charles with free breakfast and convenient casino access.
The price is $114
$137 total
includes taxes & fees
Apr 5 - Apr 6
Hampton Inn & Suites St. Charles Old Town Area
Tru by Hilton St. Charles St. Louis, MO
Tru by Hilton St. Charles St. Louis, MO
2.5 star property
St. Charles
8.6 out of 10, Excellent, (801 reviews)
  • cleanliness
    Modern hotel with free breakfast and parking near Ameristar Casino St. Charles.
The price is $114
$132 total
includes taxes & fees
Mar 22 - Mar 23
Tru by Hilton St. Charles St. Louis, MO
Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1,001 reviews)
  • cleanliness
    Peaceful riverfront hotel with easy access to St. Charles Historic District.
The price is $116
$133 total
includes taxes & fees
Apr 5 - Apr 6
Country Inn & Suites by Radisson, St. Charles Historic District
Holiday Inn Express & Suites Edwardsville by IHG
Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
Edwardsville
9.2 out of 10, Wonderful, (851 reviews)
  • cleanliness
    Discover comfort near Edwardsville Arts Center with complimentary perks and indoor pool.
The price is $146
$168 total
includes taxes & fees
Apr 5 - Apr 6
Holiday Inn Express & Suites Edwardsville by IHG
Country Hearth Inn & Suites Edwardsville St. Louis
Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
Edwardsville
8.6 out of 10, Excellent, (672 reviews)
  • cleanliness
    Peaceful Edwardsville retreat with fitness center and easy access to trails.
The price is $129
$148 total
includes taxes & fees
Mar 15 - Mar 16
Country Hearth Inn & Suites Edwardsville St. Louis
Comfort Inn Edwardsville - St. Louis
Comfort Inn Edwardsville - St. Louis
2.5 star property
Edwardsville
8.4 out of 10, Very Good, (830 reviews)
  • cleanliness
    Unwind at this tranquil Edwardsville retreat, minutes from local attractions.
The price is $107
$123 total
includes taxes & fees
Apr 5 - Apr 6
Comfort Inn Edwardsville - St. Louis
Best Western Plus Pontoon Beach
Best Western Plus Pontoon Beach
3.0 star property
Granite City
8.6 out of 10, Excellent, (835 reviews)
The price is $92
$102 total
includes taxes & fees
Apr 5 - Apr 6
Best Western Plus Pontoon Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check out pet-friendly hotels in St. Charles

You may also like hotels with pools in St. Charles

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit St. Charles?

Our prices for hotels in St. Charles are cheapest in January
Price trends for hotels in St. Charles
Pricing is based on two traveler single night rates
View properties in March
Currently viewing crowd sizes and weather for March.
Typical weather for St. Charles
March
High 13°C / low 3°C. Partly sunny.
View properties in March
13°
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March, no crowd data, average high temperature 13 degrees Celsius, average low temperature 3 degrees Celsius. Partly sunny.
18°
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April, no crowd data, average high temperature 18 degrees Celsius, average low temperature 8 degrees Celsius. Sunny most days.
24°
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May, no crowd data, average high temperature 24 degrees Celsius, average low temperature 14 degrees Celsius. Sunny most days.
14°
29°
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June, no crowd data, average high temperature 29 degrees Celsius, average low temperature 19 degrees Celsius. Sunny most days.
19°
31°
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July, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
30°
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August, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
27°
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September, no crowd data, average high temperature 27 degrees Celsius, average low temperature 16 degrees Celsius. Sunny most days.
16°
20°
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October, no crowd data, average high temperature 20 degrees Celsius, average low temperature 10 degrees Celsius. Sunny most days.
10°
13°
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November, no crowd data, average high temperature 13 degrees Celsius, average low temperature 3 degrees Celsius. Partly sunny.
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December, no crowd data, average high temperature 7 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
-1°
weather_cloudy
January, no crowd data, average high temperature 4 degrees Celsius, average low temperature -4 degrees Celsius. Cloudy most days.
-4°
weather_partly_sunny
February, no crowd data, average high temperature 6 degrees Celsius, average low temperature -3 degrees Celsius. Partly sunny.
-3°
Monthly weather averages (˚C)

Top neighborhoods in St. Charles

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Top landmarks in St. Charles

Learn more about St. Charles

Wander cobblestone streets on historic Main Street, where gas lamps illuminate shops selling everything from handcrafted jewelry to homemade fudge. The Lewis and Clark Boathouse offers a fascinating glimpse into the explorers' journey that began right here in 1804. Pedal along the Katy Trail, where the former railroad track hugs the Missouri River with views that explain why those French-Canadian fur traders settled here in the first place. The restored buildings house restaurants where locals debate which has the best bread pudding (they're all correct). At the riverfront, watch barges navigate the same waters that launched America's westward expansion. History feels remarkably present here, as if those early pioneers might stroll around the corner at any moment.

The historic 18th century Main Street through the brick paved old town of St. Charles, Missouri, along the Missouri River.

Check out reviews of St. Charles hotels guests love

Frequently asked questions

What accommodations do travelers like in St. Charles?
Can I book a refundable accommodation in St. Charles?
If you need the flexibility to change your plans to St. Charles, most properties provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in St. Charles if I want a vacation rental instead of a hotel?
If you want a good alternative to a hotel, review our selection of 86 vacation homes. You can also consider one of the 32 apartments or 8 cottages.
What will the weather in St. Charles be like during my vacation?
July and August are typically the warmest months in St. Charles when the average temp is 75°F. January and February are the coldest months when the average temperature is 37°F. May and April are the months with the most rain.
Why should I book my St. Charles hotel through Hotels.com?
There are lots of reasons to book your St. Charles trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.