Hotels in Greenville

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Where to stay in Greenville?

A modern living room with a fireplace, blue sofa, red chairs, and a flat-screen TV mounted on a textured wall.

A hotel reception area with a computer desk, a printer, a coffee machine, and a framed cityscape picture on the wall.

A hotel room with a blue armchair, a sofa, a bed, a desk, a television, and a window.

1. Comfort Inn & Suites Greenville I-70

Greenville

$100

$111 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with a bed, a television, a desk, and a chair.

A breakfast area with a counter, microwave, coffee machine, and seating.

A reception area with a reception desk, a computer, a sewing machine, and an exit sign.

2. Super 8 by Wyndham Greenville

Greenville

$63

$70 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, a desk, a chair, a TV, a mirror, and a bathroom with a bathtub and sink.

A restaurant with wooden tables and chairs, a kitchen area, and a vending machine.

A hotel lobby with a reception desk, a staircase to an upper level, a sofa, and a TV mounted on the wall.

An indoor swimming pool with clear water, surrounded by lounge chairs and a ceiling fan.

3. SureStay Hotel by Best Western Greenville

Greenville

$55

$61 total

includes taxes & fees

Oct 27 - Oct 28

A hotel room with a bed, bedside tables, a desk, a chair, a TV, and a window with curtains.

A covered outdoor area with a concrete walkway, large windows, and a building with a gray exterior.

A hotel lobby with a wooden reception desk, a round table, a clock, and a coat rack.

A motel with multiple rooms, a parking lot, and a wet ground, likely after rain.

4. Budget Inn Motel

Greenville

$55

$61 total

includes taxes & fees

Oct 24 - Oct 25

A neatly made bed with a patterned bedspread, a framed picture above it, a chair, a lamp, and a checkered floor.

A room with teal walls, a wooden desk, a chair, a television, a lamp, a microwave, and a coat rack.

A bathroom with a sink, toilet, and a stack of towels.

Two double beds with patterned headboards, a bedside table with a lamp, and framed pictures on the wall.

5. Powhatan Motel

Pocahontas

$97

$103 total

includes taxes & fees

Oct 24 - Oct 25

A hotel room with a bed, bedside table, chair, and artwork on the walls.

Two beverage dispensers with Coca-Cola and Sprite, and a snack display.

A hotel room with a blue sofa, a bed with white bedding, a nightstand, a desk with a chair, and a large window offering a view.

A clean, modern breakfast area with a bakery section, a hot food station, and a sign indicating breakfast is ready when you are.

6. Holiday Inn Express & Suites Vandalia by IHG

Vandalia

$106

$116 total

includes taxes & fees

Nov 1 - Nov 2

A lobby with a wooden staircase, a desk with a computer, and patterned armchairs.

A Ramada hotel with a brick facade, large entrance, and a clear sky.

A gym with treadmills, elliptical machines, and weight equipment.

A kitchen with white cabinets, a microwave, a coffee machine, and a refrigerator.

7. Ramada by Wyndham Vandalia

Vandalia

$72

$78 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.

A hotel room with a bed, a desk with a TV, a chair, a small table, and a couch.

A kitchen with a dishwasher, coffee makers, a water dispenser, and various kitchen utensils.

A hotel room with a sofa, two lamps, a television, and a desk.

8. Seasons Inn & Suites Highland

Highland

$94

$104 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a bed, a desk with a chair, a sofa, and a small table.

A hotel reception area with a reception desk, a clock, a television, and a seating area with an orange chair and a table.

A modern living room with a flat-screen TV, a small kitchen with wooden cabinets, a dining area with two chairs, and a staircase leading to an upper level.

A hotel lobby with a reception desk, seating area, and a TV mounted on the wall.

9. Quality Inn & Suites Vandalia near I-70 and Hwy 51

Vandalia

$64

$70 total

includes taxes & fees

Nov 5 - Nov 6

A modern living room with patterned carpet, two sofas, a coffee table, and a TV.

A hotel lobby with a reception desk, a chandelier, and a patterned carpet.

A living room with two floral-patterned sofas, a small white armchair, a red armchair, a green armchair, and a glass coffee table with a floral centerpiece.

A hotel room with two beds, a cityscape mural, a lamp, and a patterned bedspread.

10. Super 8 by Wyndham Staunton

Staunton

$80

$89 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with a clear view of the sky through the roof, surrounded by red lounge chairs and a few tables.

A Baymont by Wyndham hotel with a blue facade, a covered entrance, and a parking lot.

A restaurant with a fireplace, seating area, and a television.

A spacious lobby with a seating area, a television, and a reception desk.

11. Baymont by Wyndham Litchfield

Litchfield

$95

$104 total

includes taxes & fees

Oct 24 - Oct 25

A hotel room with a bed, a sofa, a desk with a lamp, and a painting on the wall.

A hotel with a covered parking area and a sign indicating it is a Quality Inn & Suites by EconoHotels.

A gym with various exercise equipment, a mirror, a sink, and a chair.

A spacious living room with a fireplace, a television, and a modern chandelier.

12. Quality Inn Litchfield Route 66

Litchfield

$82

$90 total

includes taxes & fees

Nov 12 - Nov 13

A restaurant with a bar area, seating, and a view of the outside.

A sign for the Americas Best Value Inn with an entrance sign.

A basic earth hair care kit with shampoo, conditioner, and body lotion tubes, and a box.

13. Americas Best Value Inn Vandalia

Vandalia

$63

$69 total

includes taxes & fees

Oct 24 - Oct 25

A hotel dining area with multiple tables and chairs, a reception desk, and a clock on the wall.

A conference room with a wooden table, six chairs, a television, and two framed pictures on the wall.

A kitchen with a granite countertop, stainless steel sink, black coffee maker, and a microwave.

A Hampton Inn hotel with a flagpole, clear signage, and a well-maintained lawn.

14. Hampton Inn by Hilton Litchfield

Litchfield

$105

$116 total

includes taxes & fees

Nov 15 - Nov 16

A white door with the number 16, a mailbox, and a small light fixture on the left.

A motel with a single-story structure, a visible entrance, and a parking lot.

A hotel room with two beds, a desk, and a chair. There are framed pictures on the walls and a lamp on the desk.

A bathroom with a bathtub, toilet, and a shower curtain.

15. Lighthouse Lodge

Pocahontas

$84

$89 total

includes taxes & fees

Oct 24 - Oct 25

An indoor swimming pool with a tiled edge, surrounded by green chairs and tables, and large windows with a view.

A hotel room with a large bed, a bedside table, a lamp, a chair, an air conditioning unit, and a window with curtains.

A hotel room with a double bed, a sofa, a desk, and a chair.

A hotel dining area with a long table, six chairs with patterned upholstery, and a large abstract painting on the wall.

16. Holiday Inn Express & Suites Litchfield West by IHG

Litchfield

$119

$131 total

includes taxes & fees

Nov 20 - Nov 21

A hotel room with a bed, a chair, a small table, a lamp, a television, and a window with curtains.

A hotel hallway with blue doors, a patterned carpet, and a light fixture on the wall.

A compact laundry area with a front-loading washer and dryer, a small countertop with a scale, and a mirror above the dryer.

A compact room with a television, a small desk, a chair, a kitchenette with a stove, and a blue door.

17. Countryside Inn

Hillsboro

$79

$87 total

includes taxes & fees

Oct 24 - Oct 25

A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

A spacious lobby with a large seating area, a reception desk, and a television.

An indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls. There are lounge chairs and a small seating area with tables.

A hotel room with two beds, a large window with curtains, a wall-mounted lamp, and a patterned carpet.

18. Best Western Plus Centralia Hotel & Suites

Centralia

$139

$156 total

includes taxes & fees

Oct 25 - Oct 26

An ice dispenser with a sign indicating it's for ice machines, a caution sign about not filling ice chests, and a plant in the foreground.

A hotel room with a bed, desk, chair, lamp, TV, and a bathroom visible through an open door.

A reception desk with a 'Welcome' sign, a mounted air conditioner, a potted plant, and a TV displaying a bar scene.

A reception desk with a large illuminated number 6, a clock above it, and various informational posters and signs around the area.

19. Motel 6 Litchfield, IL

Litchfield

$65

$71 total

includes taxes & fees

Oct 24 - Oct 25

A riverside view with a gravel path and a building with a red facade.

A calm body of water with a clear sky and scattered clouds.

A bathroom with a bathtub, a shower, and a curtain.

A hotel room with two beds, a small kitchenette, and a single nightstand with a lamp.

20. Innkeeper Motel

Hamel

$63

$70 total

includes taxes & fees

Nov 15 - Nov 16

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Go beyond your typical stay in Greenville

Pet friendly

Pool

Family friendly

Our prices for hotels in Greenville are cheapest in December

Top landmarks in Greenville

Patriot's Park

8.4/10 (14 reviews)

Patriot's Park is 1.4 mi (2.2 km) from central Greenville, why not stop by during your stay.

See properties

Greenville Country Club

7.6/10 (14 reviews)

You might want to practice your swing at Greenville Country Club, a golf course located 2.2 mi (3.5 km) from central Greenville.

See properties

Learn more about Greenville

Greenville is well-known for its attractions such as Greenville Country Club and Patriot's Park. Visitors speak highly of this family-friendly city's restaurants and small-town setting.

See all hotels in Greenville

A brick wall with a street sign reading 'GREENVILLE ST.' and a black street lamp.

Check out reviews of Greenville hotels guests love

Holiday Inn Express & Suites Vandalia by IHG

10/10 Excellent

"Our stay was very relaxing. The room was clean with a very comfortable bed! Breakfast was very good to start the day!"

Baymont by Wyndham Litchfield

8/10 Good

"Great Price, very spacious room, very comfortable bed. Bathroom could have had a little more attention during cleaning. Waffle maker was perfect, no hot food in the warmers (may have been in between preparations but ??). Had to ask for fresh coffee. Otherwise all good."

Super 8 by Wyndham Staunton

8/10 Good

"Very friendly staff. Rooms were clean and spacious for a basic hotel room. Breakfast was minimal. 5-10 minute drive to area towns with great diners and historic sties. Pleasant stay and would stay again."

Quality Inn & Suites Vandalia near I-70 and Hwy 51

8/10 Good

"Staff was courteous and helpful. Room was clean and comfortable. Great place for a quick overnight stay."

Quality Inn Litchfield Route 66

10/10 Excellent

"This property was my favorite on our recent trip! It was clean, well managed, convenient, and affordable. The breakfast choices were well stocked and there were choices. Missed having peanut butter though. For the money it was an excellent value!"

Best Western Plus Centralia Hotel & Suites

10/10 Excellent

"Check in desk staff welcoming and pleasant. Always greeted me when in was walking by. Nice polite people."

Ramada by Wyndham Vandalia

10/10 Excellent

"The room was very clean and well taken care of the staff was friendly and got my reserved room very quickly never enjoyed breakfast got up to late like the idea of leaving the key in the room saves going back to the desk when there is no reason everything I did was all ready paid for so I had no need to go to the desk but wood have liked to had more coffee in the room for wake-up one cup is just not enough and some people don’t like to go down to the lobby in the morning might think about putting more coffee in rooms. For morning wake up my and my lady friend didn’t have enough coffee other than that very nice stay very enjoyable"

Frequently asked questions

What accommodations do travelers recommend in Greenville?

Guests like Comfort Inn & Suites Greenville I-70, Super 8 by Wyndham Greenville and SureStay Hotel by Best Western Greenville.

Can I book refundable hotels in Greenville?

If you want the flexibility to change your plans to Greenville, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where should I stay in Greenville if I'm looking for a cheap accommodation?

Two inexpensive options worth considering are Comfort Inn & Suites Greenville I-70 and SureStay Hotel by Best Western Greenville.

Where can I stay in Greenville if I want a vacation home instead of a hotel?

If you want to find a good alternative to a hotel, look over our selection of 5 vacation homes.

What will the weather in Greenville be like during my vacation?

July and August are typically the warmest months in Greenville when the average temp is 74°F. January and February are the coldest months when the average temperature is 36°F. April and May are the months with the most rain.

Why should I book my Greenville hotel through Hotels.com?

There are lots of reasons to book your Greenville trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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Book Hotels in Greenville on Hotels.com

Hotels in Greenville

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Greenville?

1. Comfort Inn & Suites Greenville I-70

2. Super 8 by Wyndham Greenville

3. SureStay Hotel by Best Western Greenville

4. Budget Inn Motel

5. Powhatan Motel

6. Holiday Inn Express & Suites Vandalia by IHG

7. Ramada by Wyndham Vandalia

8. Seasons Inn & Suites Highland

9. Quality Inn & Suites Vandalia near I-70 and Hwy 51

10. Super 8 by Wyndham Staunton

11. Baymont by Wyndham Litchfield

12. Quality Inn Litchfield Route 66

13. Americas Best Value Inn Vandalia

14. Hampton Inn by Hilton Litchfield

15. Lighthouse Lodge

16. Holiday Inn Express & Suites Litchfield West by IHG

17. Countryside Inn

18. Best Western Plus Centralia Hotel & Suites

19. Motel 6 Litchfield, IL

20. Innkeeper Motel

Go beyond your typical stay in Greenville

Price trends for hotels in Greenville

Typical weather for Greenville

Top landmarks in Greenville

Patriot's Park

Greenville Country Club

Learn more about Greenville

Check out reviews of Greenville hotels guests love

Holiday Inn Express & Suites Vandalia by IHG

Baymont by Wyndham Litchfield

Super 8 by Wyndham Staunton

Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn Litchfield Route 66

Best Western Plus Centralia Hotel & Suites

Ramada by Wyndham Vandalia

Frequently asked questions

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