Hotels in Santee
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Check prices for these dates
Tonight
Aug 20 - Aug 21Tomorrow
Aug 21 - Aug 22This weekend
Aug 21 - Aug 23Next weekend
Aug 28 - Aug 30Top 5 hotels in Santee at a glance
- Tru By Hilton Santee — 2.5-star hotel in Santee. Guest rating: 9.2/10 — Wonderful.
- Baymont by Wyndham Santee — 2.5-star hotel in Santee. Guest rating: 8.0/10 — Very Good.
- Hampton Inn Santee-I-95 — 2.5-star hotel in Santee. Guest rating: 9.6/10 — Exceptional.
- Best Western Plus Santee Inn — 2.5-star hotel in Santee. Guest rating: 8.8/10 — Excellent.
- Fairfield Inn & Suites by Marriott Santee — 3-star hotel in Santee. Guest rating: 9.8/10 — Exceptional.
Where to stay in Santee?
Tru By Hilton Santee
Tru By Hilton SanteeSantee
$98
$108 total
includes taxes & fees
Aug 30 - Aug 31
Baymont by Wyndham Santee
Baymont by Wyndham SanteeSantee
$80
$89 total
includes taxes & fees
Aug 23 - Aug 24
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95Santee
$123
$137 total
includes taxes & fees
Sep 7 - Sep 8
Best Western Plus Santee Inn
Best Western Plus Santee InnSantee
$111
$123 total
includes taxes & fees
Aug 30 - Aug 31
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
$134
$149 total
includes taxes & fees
Aug 27 - Aug 28
Holiday Inn Santee by IHG
Holiday Inn Santee by IHGSantee
$104
$115 total
includes taxes & fees
Aug 23 - Aug 24
Comfort Inn & Suites Santee
Comfort Inn & Suites SanteeSantee
$101
$113 total
includes taxes & fees
Sep 13 - Sep 14
Travelodge by Wyndham Santee
Travelodge by Wyndham SanteeSantee
$64
$71 total
includes taxes & fees
Sep 3 - Sep 4
Super 8 by Wyndham Santee/I-95
Super 8 by Wyndham Santee/I-95Santee
$64
$71 total
includes taxes & fees
Aug 27 - Aug 28
Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95Santee
$54
$66 total
includes taxes & fees
Sep 10 - Sep 11
Red Roof Inn Santee
Red Roof Inn SanteeSantee
$63
$70 total
includes taxes & fees
Aug 24 - Aug 25
Econo Lodge Santee
Econo Lodge SanteeSantee
$58
$64 total
includes taxes & fees
Sep 13 - Sep 14
Ramada by Wyndham Santee I-95
Ramada by Wyndham Santee I-95Santee
$67
$75 total
includes taxes & fees
Aug 30 - Aug 31
Red Roof Inn Orangeburg
Red Roof Inn OrangeburgOrangeburg
$58
$65 total
includes taxes & fees
Aug 27 - Aug 28
Doyles B and B at Players course LLC
Doyles B and B at Players course LLCManning
$181
$201 total
includes taxes & fees
Aug 21 - Aug 22
Hampton Inn Manning
Hampton Inn ManningManning
$119
$132 total
includes taxes & fees
Sep 7 - Sep 8
Bells Marina & Resort
Bells Marina & ResortEutawville
$67
$78 total
includes taxes & fees
Aug 23 - Aug 24
SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western ManningManning
$92
$102 total
includes taxes & fees
Sep 6 - Sep 7
Tru by Hilton Orangeburg
Tru by Hilton OrangeburgOrangeburg
$114
$127 total
includes taxes & fees
Sep 3 - Sep 4
Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott OrangeburgOrangeburg
$101
$112 total
includes taxes & fees
Aug 24 - Aug 25
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$80
per night
$89 total
includes taxes & fees
$119
per night
$132 total
includes taxes & fees
$111
per night
$123 total
includes taxes & fees
Sign in for extra savings
$135
per night
$150 total
includes taxes & fees
$149
per night
$165 total
includes taxes & fees
$64
per night
$71 total
includes taxes & fees
$134
per night
$149 total
includes taxes & fees
$64
per night
$77 total
includes taxes & fees
$8 off
Ramada by Wyndham Santee I-95$75
per night
$83 total
includes taxes & fees
$70
per night
$78 total
includes taxes & fees
$75
per night
$83 total
includes taxes & fees
$75
per night
$83 total
includes taxes & fees
$100
per night
$111 total
includes taxes & fees
$129
per night
$143 total
includes taxes & fees
$120
per night
$133 total
includes taxes & fees
Sign in for extra savings
$70
per night
$78 total
includes taxes & fees
$144
per night
$160 total
includes taxes & fees
$170
per night
$189 total
includes taxes & fees
$74
per night
$88 total
includes taxes & fees
$165
per night
$183 total
includes taxes & fees
$174
per night
$193 total
includes taxes & fees
$80
per night
$89 total
includes taxes & fees
$90
per night
$100 total
includes taxes & fees
$10 off
Ramada by Wyndham Santee I-95$91
per night
$101 total
includes taxes & fees
$84
per night
$94 total
includes taxes & fees
$118
per night
$262 total
includes taxes & fees
$141
per night
$313 total
includes taxes & fees
$125
per night
$277 total
includes taxes & fees
Sign in for extra savings
$100
per night
$222 total
includes taxes & fees
Sign in for extra savings
$130
per night
$289 total
includes taxes & fees
$157
per night
$348 total
includes taxes & fees
$140
per night
$311 total
includes taxes & fees
$22 off
Quality Inn & Suites Santee I-95$63
per night
$151 total
includes taxes & fees
$70
per night
$156 total
includes taxes & fees
$77
per night
$170 total
includes taxes & fees
$72
per night
$160 total
includes taxes & fees
$25 off
Econo Lodge Santee$72
per night
$159 total
includes taxes & fees
$88
per night
$195 total
includes taxes & fees
Patio + Pool Table: Lake Marion Getaway
Patio + Pool Table: Lake Marion GetawaySantee
Check out pet-friendly hotels in Santee
$98
$108 total
includes taxes & fees
Aug 30 - Aug 31
$80
$89 total
includes taxes & fees
Aug 23 - Aug 24
$111
$123 total
includes taxes & fees
Aug 30 - Aug 31
$123
$137 total
includes taxes & fees
Sep 7 - Sep 8
$104
$115 total
includes taxes & fees
Aug 23 - Aug 24
$134
$149 total
includes taxes & fees
Aug 27 - Aug 28
$64
$71 total
includes taxes & fees
Sep 3 - Sep 4
$64
$71 total
includes taxes & fees
Aug 27 - Aug 28
$54
$66 total
includes taxes & fees
Sep 10 - Sep 11
$63
$70 total
includes taxes & fees
Aug 24 - Aug 25
You may also like hotels with pools in Santee
$98
$108 total
includes taxes & fees
Aug 30 - Aug 31
$123
$137 total
includes taxes & fees
Sep 7 - Sep 8
$134
$149 total
includes taxes & fees
Aug 27 - Aug 28
$104
$115 total
includes taxes & fees
Aug 23 - Aug 24
$111
$123 total
includes taxes & fees
Aug 30 - Aug 31
$101
$113 total
includes taxes & fees
Sep 13 - Sep 14
$54
$66 total
includes taxes & fees
Sep 10 - Sep 11
$64
$71 total
includes taxes & fees
Aug 27 - Aug 28
$67
$75 total
includes taxes & fees
Aug 30 - Aug 31
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Santee
Pet friendly
Family friendly
Our prices for hotels in Santee are cheapest in November
Our prices for hotels in Santee are cheapest in November
Price trends for hotels in Santee
Pricing is based on two traveler single night rates
Top landmarks in Santee
Santee State Park
8.0/10 (219 reviews)
Santee State Park is 2.7 mi (4.4 km) from central Santee, why not stop by during your stay.
Santee Cooper Country Club
7.8/10 (94 reviews)
You might want to play some rounds at Santee Cooper Country Club, located 0.6 mi (1 km) from central Santee. If Santee Cooper Country Club doesn't quite scratch your golfing itch, Santee National Golf Club is also nearby.
Santee National Golf Club
8.0/10 (74 reviews)
You might want to practice your swing at Santee National Golf Club, a golf course located 0.8 mi (1.4 km) from central Santee. If Santee National Golf Club doesn't quite scratch your golfing itch, Santee Cooper Country Club is also nearby.
Santee Town Hall
Santee Town Hall is worth a visit, located 1 mi (1.6 km) from central Santee.
Learn more about Santee
Tee off at championship golf courses or cast a line in Lake Marion's fish-rich waters where locals claim the bass practically jump into your boat. The Santee National Wildlife Refuge offers hiking trails where alligators sun themselves with reptilian nonchalance. Interstate 95 crosses the lake on a causeway that provides views worth pulling over for (safely, of course). Santee State Park delivers lakeside tranquility that makes visitors forget their phones exist. This resort town punches well above its weight with dining options that range from fresh-caught catfish to surprisingly sophisticated fare. The recent addition of the Santee Cooper Regional Water System has locals buzzing about growth while still cherishing their small-town atmosphere.
See all hotels in Santee
Check out reviews of Santee hotels guests love
Fairfield Inn & Suites by Marriott Santee
10/10 Excellent
"Clean"
Best Western Plus Santee Inn
10/10 Excellent
"We've been staying in this hotel on our way to SC since I was a kid and now I stop here with my own kids. It's always clean, welcoming and has great breakfast. They added a little gift shop to the lobby which is very cute. The rooms are not the most up-to-date as other hotels but they are clean and comfortable."
Tru By Hilton Santee
10/10 Excellent
"Great Galway point between DC and FL —Cel was great — wonderful Lavazza coffee."
Travelodge by Wyndham Santee
8/10 Good
"The staff was very helpful and respectful."
Quality Inn & Suites Santee I-95
10/10 Excellent
"I love the hotel the staff was great and breakfast was awesome"
Hampton Inn Santee-I-95
10/10 Excellent
"Our room had that fresh air clean smell when we entered, the hotel looked spotless. Our bed was comfortable… the breakfast was on point.,, we use Hampton when we travel down East …. We came down for an overnight stay to attend a funeral…. The location was perfect…We love Hampton Inn"
Ramada by Wyndham Santee I-95
8/10 Good
"The price rate was great"
Red Roof Inn Santee
10/10 Excellent
"Clean rooms and staff was great"