Hotels in Centerville
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Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.0 out of 10, Wonderful, (585)
9.0/10
Wonderful
(585)
The price is $103
$103
$114 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Country Inn & Suites by Radisson, Anderson, SC
Country Inn & Suites by Radisson, Anderson, SC
2.5 star property
Anderson
8.4 out of 10, Very Good, (1000)
8.4/10
Very Good
(1000)
The price is $112
$112
$124 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Comfort Suites Anderson-Clemson
Comfort Suites Anderson-Clemson
2.5 star property
Anderson
8.4 out of 10, Very Good, (1003)
8.4/10
Very Good
(1003)
The price is $107
$107
$119 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Courtyard Marriott Clemson
Courtyard Marriott Clemson
3.0 star property
Clemson
9.0 out of 10, Wonderful, (523)
9.0/10
Wonderful
(523)
The price is $119
$119
$132 total
includes taxes & fees
Dec 30 - Dec 31
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1000)
9.0/10
Wonderful
(1000)
The price is $109
$109
$135 total
includes taxes & fees
Dec 30 - Dec 31
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (745)
9.8/10
Exceptional
(745)
The price is $169
$169
$188 total
includes taxes & fees
Dec 30 - Dec 31
Hampton Inn Clemson-University Area
Hampton Inn Clemson-University Area
2.5 star property
Clemson
8.8 out of 10, Excellent, (623)
8.8/10
Excellent
(623)
The price is $110
$110
$122 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1003)
8.2/10
Very Good
(1003)
The price is $84
$84
$93 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Inn at Patrick Square
The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (786)
9.8/10
Exceptional
(786)
The price is $149
$149
$165 total
includes taxes & fees
Dec 30 - Dec 31
Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.6 out of 10, Exceptional, (961)
9.6/10
Exceptional
(961)
The price is $149
$149
$165 total
includes taxes & fees
Dec 30 - Dec 31
Holiday Inn Express & Suites Clemson by IHG
Holiday Inn Express & Suites Clemson by IHG
2.5 star property
Clemson
8.8 out of 10, Excellent, (950)
8.8/10
Excellent
(950)
The price is $118
$118
$131 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Inn @ Clemson
Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very Good, (1002)
8.0/10
Very Good
(1002)
The price is $89
$89
$99 total
includes taxes & fees
Dec 30 - Dec 31
Fairfield Inn & Suites by Marriott Anderson Clemson
Fairfield Inn & Suites by Marriott Anderson Clemson
2.5 star property
Anderson
9.0 out of 10, Wonderful, (567)
9.0/10
Wonderful
(567)
The price is $89
$89
$99 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Holiday Inn Anderson by IHG
Holiday Inn Anderson by IHG
3.0 star property
Anderson
8.8 out of 10, Excellent, (698)
8.8/10
Excellent
(698)
The price is $100
$100
$111 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Abernathy of Clemson
The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (558)
9.6/10
Exceptional
(558)
The price is $149
$149
$165 total
includes taxes & fees
Dec 30 - Dec 31
Best Western Seneca-Clemson
Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very Good, (642)
8.4/10
Very Good
(642)
The price is $89
$89
$98 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (668)
9.2/10
Wonderful
(668)
The price is $121
$121
$134 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very Good, (1005)
8.2/10
Very Good
(1005)
The price is $103
$103
$114 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Liberty Hall Bed and Breakfast
Liberty Hall Bed and Breakfast
4.0 star property
Pendleton
10.0 out of 10, Exceptional, (78)
10/10
Exceptional
(78)
The price is $168
$168
$237 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (800)
9.2/10
Wonderful
(800)
The price is $105
$105
$115 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Centerville
Apartment
Family friendly
Cottage
Pet friendly
Check out reviews of Centerville hotels guests love
Days Inn by Wyndham Anderson
10/10 Excellent
"Love it"
Hampton Inn Anderson/ Alliance Business Park
10/10 Excellent
"Room was excellent. Food was excellent. Staff is very nice. "
Tru by Hilton Seneca Clemson
10/10 Excellent
"Staff is amazing, hotel and amenities are great. "
Best Western Plus Clemson Hotel & Conference Center
10/10 Excellent
"This hotel was up-to-date, seemingly remodeled recently. I would definitely stay here again. "
Comfort Inn & Suites Clemson - University Area
10/10 Excellent
"Great area behind the hotel to walk my dog!!"
Home2 Suites by Hilton Anderson Downtown
10/10 Excellent
"An easy and convenient place to stay!"
Baymont by Wyndham Anderson Clemson
10/10 Excellent
"Everything was great"
Hampton Inn & Suites Seneca-Clemson Area
10/10 Excellent
"Rooms are clean, nice place"
Inn @ Clemson
10/10 Excellent
"No frills, comfy clean rooms in an older hotel. "
Frequently asked questions
What accommodations do travelers like in Centerville?
Can I book a refundable hotel in Centerville?
If you want the flexibility to change your travel plans to Centerville, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Centerville be like during my trip?
July and August are typically the warmest months in Centerville when the average temp is 77°F. January and February are the coldest months when the average temperature is 47°F. December and April are the months with the most rain.
Why should I book my Centerville hotel through Hotels.com?
There are lots of reasons to book your Centerville trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.