Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Oxbow Park is 3.4 mi (5.5 km) from central Byron, why not stop by during your stay. Our travelers also like this walkable area for its restaurants. If you like Oxbow Park, you'll love Douglas State Trail Head Rochester, just a short drive away.
You can search for that perfect souvenir at High Point Shopping Center during your trip to Byron. Amble around the area's parks or experience its art scene.
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
10/10 Excellent
"Exceptional Being a Mayo patient, and trying 3 other properties, this by far is the best The Housekeeping far exceed other competitors Our room was vert spacious The bed was comfy as were pillows TJ Maxx is walkable as is the Health Food store Sports Bar is just off hotel parking lot All the staff very helpful and efficient Water Park pool is in hotel There’s an adequate gym "
If you're looking for the flexibility to change your plans to Byron, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Byron be like during my vacation?
July and August are typically the warmest months in Byron when the average temp is 67°F. January and February are the coldest months when the average temperature is 21°F. June and May are the months with the most rain.
Why should I book my Byron hotel with Hotels.com?
There are lots of reasons to book your Byron trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.
Find out more about Byron
Find out more about Byron
If you're looking to discover somewhere new, look no further than Byron. Whether you're planning to stay for a night or for the week, the area around Byron has accommodations to fit every need. Search for hotels in Byron with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Byron hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Byron hotel deals are here with our lowest price guarantee.
