Hotels in Santa Ana

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A hotel corridor with wooden doors, a central white reception desk, and a staircase leading to an upper level.

A group of people in a dimly lit room with tables and chairs, some holding drinks.

A restaurant interior with a brick wall, a pizza oven, bar stools, and a sign indicating a private event.

A hotel room with a bed, a desk, a chair, a plant, and a chandelier.

1. Hotel Caracas - Casco Viejo

Santa Ana

Lital

$46

$51 total

includes taxes & fees

Oct 18 - Oct 19

A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

A modern kitchen with a large window, a dining area with chairs, and a view of the city.

A modern kitchen with a central island, stainless steel appliances, and a dining area with black chairs.

A balcony with a view of the sea, a table with a vase and a candle, and a chair.

2. Casco View Life Residences

Santa Ana

Glenn

$84

$122 total

includes taxes & fees

Oct 16 - Oct 17

A hotel room with a large bed, a window with curtains, a city view, and a lamp.

A corridor with tiled flooring, doors, and a fire extinguisher mounted on the wall.

A multi-story building with a flat facade, multiple balconies, and a sign indicating it is a public building.

A balcony with a city view, featuring a curved railing and a palm tree.

3. Hotel República

Santa Ana

Danilo

$29

$92 total

includes taxes & fees

Oct 16 - Oct 17

A bar area with a curved counter, multiple seating options, and a variety of bottles and glasses on display.

A teal wall-mounted rack with multiple circular slots, likely for hanging items.

A bathroom with a shower, a window with a view, and a potted plant on the windowsill.

A multi-story hotel with a blue and yellow facade, named HOTEL RIAZOR.

4. Hotel Riazor

Santa Ana

Del

$27

$30 total

includes taxes & fees

Oct 16 - Oct 17

An indoor dining area with tables and chairs, a mural on the wall, and hanging plants.

A living room with wicker furniture, a yellow sofa, and a bookshelf.

A hallway with a wooden door marked '14', a window, and a staircase with a railing.

A staircase with white walls and a blue wall at the top. There are green and black safety lines on the stairs.

5. Hostal La Cigarra

Santa Ana

Mark

$29

$32 total

includes taxes & fees

Oct 16 - Oct 17

A dining area with a round glass table, two chairs, a potted plant, a vase with flowers, a bottle of wine, and a plate with apples.

A modern kitchen with a gas stove, microwave, and stainless steel refrigerator.

A multi-story building with balconies, a staircase, and a website address on the facade.

A lobby with green seating, a colorful mural, and a brick wall.

6. Casco View Apartments & Rooftop Pool

Santa Ana

$85

$94 total

includes taxes & fees

Oct 20 - Oct 21

A hotel entrance with a green facade and a metal fence.

A living room with a television on a stand, a Christmas tree, and a small table with two chairs.

A neatly made bed with a teal bedspread, two pillows, and two towels folded at the foot of the bed. There is a wooden nightstand with a phone and a small table beside the bed.

A reception desk with a green wall and a sign that reads "CASCO HOTEL".

7. ART CASCO The Hotel

Santa Ana

Eldris

$37

$41 total

includes taxes & fees

Oct 16 - Oct 17

A modern hotel room with a large bed, a sofa, a TV, and a view of the city.

A modern kitchen with a bar area, green bar stools, a stainless steel refrigerator, and a patterned floor.

A modern hotel room with a large bed, a wooden headboard, a hanging plant, and a view of the kitchen area.

A modern living room with a geometric patterned floor, a white sofa set, a coffee table, and a TV mounted on the wall.

8. La Manzana Barrio Vivo by Wynwood

Santa Ana

Javier Alberto Lindauer

$84

$120 total

includes taxes & fees

Oct 18 - Oct 19

A modern living room with a flat-screen TV, a dark-colored sofa, a glass coffee table, and a dining area with chairs and a table.

A panoramic view from a high balcony overlooking a marina with boats, a coastal town, and a bridge.

A modern dining area with grey sofas and blue chairs, large windows offering a view of the sea and cityscape.

9. Room-sofa Bed Stay Rooftop Pool & Gym, A

Santa Ana

Cristian Camilo Betancur

$97

$106 total

includes taxes & fees

Oct 19 - Oct 20

A hotel named PRINCIPE with a modern facade and large glass windows.

A swimming pool with lounge chairs and a table.

A hotel lobby with a reception desk, seating area, and a visible sign for 'PRINCIPES HOTEL & SQUITES'.

A hotel reception area with a modern design, featuring a reception desk, white chairs, and a visible fire feature.

10. Principe Hotel and Suites

El Cangrejo, 3.9 km from Santa Ana

machelle

$59

$65 total

includes taxes & fees

Oct 16 - Oct 17

A modern lobby with a chandelier, seating area, reception desk, and a staircase.

A dining area with a glass table, wicker chairs, a plate of fruit, and a cocktail glass.

A hotel dining area with wicker chairs, a bar counter, and pendant lighting.

A modern hotel lobby with a marble reception desk, comfortable seating, a large painting, and a large plant.

11. The Executive Hotel

Campo Alegre, 3.2 km from Santa Ana

Matthew

$80

$88 total

includes taxes & fees

Nov 8 - Nov 9

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.

A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.

A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

12. Hotel Riu Plaza Panama

Campo Alegre, 3.6 km from Santa Ana

Rocky Lee

$118

$130 total

includes taxes & fees

Oct 25 - Oct 26

A rooftop bar with a city skyline view, outdoor seating, and a bar area with bottles and glasses.

A hotel room with a large bed, a painting on the wall, a door, and a small table with a lamp.

A modern living room with a purple wall, two abstract paintings, a white sofa with colorful cushions, a wooden coffee table with books and bottles, and patterned floor tiles.

A room with a kitchenette, a sofa, a bed, and a mural with the phrase "Just Breathe".

13. Tantalo Hotel

San Felipe, 0.7 km from Santa Ana

SUSAN

$83

$91 total

includes taxes & fees

Nov 9 - Nov 10

A spacious living room with blue sofas, a marble coffee table, and framed pictures on the walls.

A blue building with arched windows and balconies, labeled 'Magnolia.'

A bedroom with a large bed, white walls, and a view of a building through arched windows.

14. Hotel Magnolia Boutique

San Felipe, 0.7 km from Santa Ana

Layal

$89

$98 total

includes taxes & fees

Oct 20 - Oct 21

A hotel room with a bed, a desk with a computer, a chair, a mirror, and a staircase.

A spacious living area with a staircase leading to a second floor, a sofa, a TV, and a dining area.

A spacious living area with a staircase leading to a loft, a large mirror, and a television.

A balcony with a view of a city skyline, a river, and a large tree.

15. Hotel Bardot Boutique

San Felipe, 1.1 km from Santa Ana

Gabriela

$86

$95 total

includes taxes & fees

Oct 20 - Oct 21

A hotel entrance with a covered walkway, large windows, and a well-maintained garden area.

A spacious lobby with a blue sofa set, a coffee table, and a green ottoman. There is a large window with a view of palm trees outside.

A hotel reception area with a desk, chairs, and a computer.

A hotel room with a bed, a desk, a chair, and a sofa.

16. Hotel Milan

El Cangrejo, 3.6 km from Santa Ana

Dan

$40

$44 total

includes taxes & fees

Oct 16 - Oct 17

A balcony with a view of a cityscape, including a river and a bridge.

A living room with a sofa, coffee table, TV, and artwork on the walls.

A high-rise building with a glass elevator shaft, a metal railing on the balcony, and a sign with the letters "OASIS".

A bedroom with a sloped ceiling, a bed with white bedding, a small wooden drying rack, a patterned rug, and an air conditioning unit.

17. Oasis Hotel

San Felipe, 0.6 km from Santa Ana

Maura

$59

$65 total

includes taxes & fees

Nov 12 - Nov 13

A resort with a pool area, lounge chairs, and a view of a bridge at night.

A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.

A bar area with a counter, stools, and a seating area with tables and chairs.

A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.

18. Radisson Hotel Panama Canal

Amador, 2.3 km from Santa Ana

Tilmann

$78

$86 total

includes taxes & fees

Oct 16 - Oct 17

A balcony with wicker chairs and a view of the cityscape.

A hotel room with a large bed, a desk with a lamp, a chair, and a view of a cityscape through a window.

A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.

A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.

19. Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco, 5.1 km from Santa Ana

Leonel

$95

$105 total

includes taxes & fees

Nov 9 - Nov 10

A hotel room with a large bed, a desk with a chair, a TV, and a view of a cityscape through large windows.

A modern hotel lobby with a wooden reception desk, seating area, and a view of the cityscape.

A modern gym with treadmills, a rowing machine, and dumbbells.

A modern interior with two wicker chairs, a small table with a potted orchid, and a view through a frosted glass partition.

20. TRYP by Wyndham Panamá Centro

El Cangrejo, 3.5 km from Santa Ana

Nathan A

$87

$95 total

includes taxes & fees

Nov 5 - Nov 6

View all properties

Compare popular hotels in Santa Ana

Property	Property class	Guest rating
Casco View Life Residences	9.0 Wonderful 112 reviews	View
Hotel Caracas - Casco Viejo	8.0 Very good 20 reviews	View
Hostal La Cigarra	7.6 Good 75 reviews	View
Hotel República	6.8 Good 197 reviews	View
ART CASCO The Hotel	6.0 Good 15 reviews	View

Our prices for hotels in Santa Ana are cheapest in February

Top landmarks in Santa Ana

El Machetazo Santa Ana

If you want to give your credit card some exercise, head out to El Machetazo Santa Ana in Santa Ana. Splash some more cash at Avenida Central and Paseo de Las Bovedas.

See properties

Check out reviews of Santa Ana hotels guests love

Courtyard by Marriott Panama Multiplaza Mall

8/10 Good

"Overall, we had a pleasant stay. Check-in was quick and smooth, and the staff were very helpful. The breakfast staff were especially friendly and attentive. The rooms were comfortable and well maintained, housekeeping was excellent, and the hotel was clean and well kept. The only disappointment was the dining options. The bar had a very limited food menu, and the dinner options at the hotel were not up to standard, with very little variety. The biggest advantage is the location, with Multiplaza Mall right next door, offering excellent shopping, restaurants, and everything you need within walking distance."

Hotel Riu Plaza Panama

10/10 Excellent

"Me encantó"

Central Hotel Panama Casco Viejo

8/10 Good

"We had a great stay. You can't beat the location. The beds are comfortable and the room was very spacious. The property is clean and well maintained. The biggest issue was the dust. Our room was super dusty, every surface when we checkedn in. They were doing some renos. Even though our suit was away from the main lobby area, we had to sleep with ear plugs since the music traveled from the lobby and we could hear it even in our room. In the morning we also heard all the cleaning staff moving about and doing laundry. Woke is up st 07:30. We also never got our free welcome sparkling wine. They kept sending us from restaurant to restaurant so we eventually gave up."

Crowne Plaza Panama Airport by IHG

10/10 Excellent

"Friendly service and staff."

Principe Hotel and Suites

10/10 Excellent

"Wonderful budget minded hotel. No Mini fridge or coffee maker. However, there is a 24 hour market next door with an automatic coffee maker. We would stay again."

Hotel Ojos del Rio

10/10 Excellent

"Place was nice and quiet and was a comfortable stay."

Aloft by Marriott Panama

10/10 Excellent

"Great staff and great location! Highly recommend!"

Waymore Hotel Spa & Casino

8/10 Good

"I love the fact that the police and security was always present around the hotel. I think the breakfast buffet need to offer 2 types of juices daily instead of only orange juice as for the restaurant I think you all chicken soup was very tasty"

Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent

"Excelente lugar y centrico para todo en la Ciudad."

Find out more about Santa Ana

Hotels in Santa Ana

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Santa Ana?

1. Hotel Caracas - Casco Viejo

2. Casco View Life Residences

3. Hotel República

4. Hotel Riazor

5. Hostal La Cigarra

6. Casco View Apartments & Rooftop Pool

7. ART CASCO The Hotel

8. La Manzana Barrio Vivo by Wynwood

9. Room-sofa Bed Stay Rooftop Pool & Gym, A

10. Principe Hotel and Suites

11. The Executive Hotel

12. Hotel Riu Plaza Panama

13. Tantalo Hotel

14. Hotel Magnolia Boutique

15. Hotel Bardot Boutique

16. Hotel Milan

17. Oasis Hotel

18. Radisson Hotel Panama Canal

19. Ramada Plaza by Wyndham Panama Punta Pacifica

20. TRYP by Wyndham Panamá Centro

Compare popular hotels in Santa Ana

Price trends for hotels in Santa Ana

Typical weather for Panama City

Top landmarks in Santa Ana

El Machetazo Santa Ana

Check out reviews of Santa Ana hotels guests love

Courtyard by Marriott Panama Multiplaza Mall

Hotel Riu Plaza Panama

Central Hotel Panama Casco Viejo

Crowne Plaza Panama Airport by IHG

Principe Hotel and Suites

Hotel Ojos del Rio

Aloft by Marriott Panama

Waymore Hotel Spa & Casino

Ramada Plaza by Wyndham Panama Punta Pacifica