A bridge spanning a body of water with a city skyline in the background during sunset.

Hotels near Mississippi River

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Where to stay near Mississippi River?

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

1. Sleep Inn & Suites Hannibal West

30.3 km from Mississippi River

Polly

$116

$135 total

includes taxes & fees

Oct 11 - Oct 12

A gazebo with a table and benches, surrounded by trees and a body of water.

A two-story building with a flat roof and a covered entrance. There are two cars parked in front, and a truck is visible on the left.

A hotel room with a bed, two sofas, a small table, a desk with a chair, a TV, and a potted plant.

A hotel room with a bed, a desk, a chair, a television, a microwave, and a lamp.

2. River's Edge Motel

13.6 km from Mississippi River

Greg

$83

$94 total

includes taxes & fees

Sep 29 - Sep 30

A restaurant with a bar area, wooden flooring, checkered tablecloths, and a brick wall.

A downtown area with a mix of historic and modern buildings, a prominent Mercantile Bank, and a view of a lake.

A bedroom with a brick wall, a wooden bed, two bedside tables with lamps, and a ceiling fan.

A row of multi-story buildings with a variety of storefronts, including a coffee shop and a restaurant.

3. The Eagles Nest Inn

14.2 km from Mississippi River

Judith

$113

$128 total

includes taxes & fees

Sep 29 - Sep 30

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

4. Best Western On The River

25.3 km from Mississippi River

Robert

$110

$127 total

includes taxes & fees

Oct 1 - Oct 2

A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

A wooden table with a bottle of champagne, two glasses, and scattered rose petals.

A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

A historic building with a stone facade and multiple windows, featuring a sign about Tom Sawyer's fence.

5. Riverside Inn Hannibal

25.1 km from Mississippi River

Philip

$171

$232 total

includes taxes & fees

Sep 29 - Sep 30

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

A hotel entrance with a central fountain, large columns, and a clear sky.

6. Quality Inn & Suites Hannibal West

30 km from Mississippi River

Dawn

$80

$93 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a large bed, a desk with a computer, a television, and a bathtub.

A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.

A hotel room with a bathtub, two yellow armchairs, a desk with a chair, a small table, and a lamp.

A bar area with a long counter, multiple bottles, glasses, and a few chairs.

7. Oak Hill Inn & Suites

71.8 km from Mississippi River

Tracy

$112

$128 total

includes taxes & fees

Sep 29 - Sep 30

A hotel room with a bed, a sofa, a desk, and a lamp.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

A restaurant with multiple tables and chairs, an exit sign, and a counter area.

A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

8. Comfort Inn & Suites - Hannibal

26.2 km from Mississippi River

Wendy

$77

$91 total

includes taxes & fees

Oct 4 - Oct 5

A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

A fireplace with decorative elements, framed pictures, and a vase of red flowers.

A cozy living room with a fireplace, a red armchair, a globe, and various framed pictures on the mantel.

A dining area with a table set for four, surrounded by wooden chairs. A chandelier hangs above the table, and a lamp provides additional lighting.

9. Garden House Bed and Breakfast

25.2 km from Mississippi River

Randolph

$93

$107 total

includes taxes & fees

Sep 29 - Sep 30

A modern kitchen with wooden cabinets, a granite countertop, a coffee machine, a microwave, a toaster, and a refrigerator.

A compact living space with a dining table, two chairs, a sofa, a desk, and a kitchenette.

A compact living space with a kitchenette, a sofa, a patterned armchair, and a television.

10. Heritage Hotel Quincy

47.8 km from Mississippi River

Gary

$78

$89 total

includes taxes & fees

Oct 5 - Oct 6

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A swimming pool with lounge chairs and a covered seating area.

A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

11. Lighthouse Inn & Suites

25.8 km from Mississippi River

Mary Ann

$188

$216 total

includes taxes & fees

Sep 29 - Sep 30

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

A building with a covered entrance and a sign indicating a clearance height of 13 feet.

A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

A coffee station with a coffee machine, cups, and a sign that says "RISE & SHINE."

12. Motel 6 Hannibal, MO

26.1 km from Mississippi River

Darlene

$58

$67 total

includes taxes & fees

Sep 29 - Sep 30

A hotel room with a bed, a desk with a computer, a TV, and a bathroom with a shower.

A hotel entrance with a sign reading "Quality Inn & Suites by Choice Hotels".

A modern kitchen with dark cabinets, a central island with bar stools, and pendant lighting.

A hotel room with a bed, a desk with a chair, a television, and a dining area with chairs.

13. Quality Inn & Suites Quincy - Downtown

47.8 km from Mississippi River

James

$119

$136 total

includes taxes & fees

Oct 29 - Oct 30

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

A patio with red Adirondack chairs and a table, surrounded by a pebble border.

A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

A long hallway with a patterned carpet, wooden paneling on the walls, and a ceiling light.

14. Super 8 by Wyndham Hannibal

26.3 km from Mississippi River

Roy

$62

$71 total

includes taxes & fees

Oct 26 - Oct 27

A hot tub with a rocky backdrop and a mural.

A restaurant with wooden walls, a bar area, and multiple seating arrangements.

A cozy log cabin interior with a fireplace, wooden furniture, and a television mounted on the wall.

An indoor swimming pool with a 'No Diving' sign, lounge chairs, and a mural on the wall.

15. Stoney Creek Inn Quincy

46.5 km from Mississippi River

Anonymous traveler

$134

$153 total

includes taxes & fees

Oct 4 - Oct 5

A buffet with various food items, including omelets and cheese.

A Holiday Inn Express hotel with a brick facade, multiple windows, and a parking lot with several cars.

A hotel room with a large bed, a desk with a computer, a TV, and a window with a view.

A coffee station with two espresso machines, a coffee grinder, and various coffee accessories.

16. Holiday Inn Express & Suites Wentzville St Louis West by IHG

86.2 km from Mississippi River

Jeanith

$139

$165 total

includes taxes & fees

Oct 4 - Oct 5

A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.

An outdoor patio with tables and chairs, green umbrellas, and string lights.

A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.

A spacious lobby with a fireplace, seating area, and large windows.

17. Holiday Inn Quincy East by IHG

46.1 km from Mississippi River

Joyce

$127

$145 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with two beds, a wooden headboard, a nightstand with a phone and lamp, and a large sunset painting above the beds.

A laundry room with a washing machine, dryer, and a shelf with detergent bottles.

A corner kitchenette with a refrigerator, coffee maker, and food display.

A kitchenette with a bread display, a microwave, a toaster, and a coffee maker on a small table.

18. Days Inn by Wyndham Hannibal

26.4 km from Mississippi River

Cordon

$56

$65 total

includes taxes & fees

Oct 4 - Oct 5

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A gym with treadmills, stationary bikes, and a weight machine.

A spacious lobby with a large sectional sofa, a reception desk, and a bar area.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

19. Drury Plaza Hotel St. Louis St. Charles

104 km from Mississippi River

Jeff

$136

$158 total

includes taxes & fees

Oct 12 - Oct 13

A spacious lobby with a high ceiling, a dining area, and a seating area with sofas and a coffee table.

A spacious lobby with a blue sofa, round coffee table, and blue chairs. There is a reception desk and a seating area with a high ceiling and large windows.

An indoor swimming pool with clear blue water, a tiled floor, and a ceiling with square vents.

A hotel room with a bed, a dresser, a nightstand with a lamp, a framed map on the wall, and a carpeted floor.

20. Drury Inn & Suites St. Louis St. Peters

95.3 km from Mississippi River

Martha

$110

$126 total

includes taxes & fees

Oct 4 - Oct 5

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Compare popular hotels close to Mississippi River

Property	Property class	Guest rating
Sleep Inn & Suites Hannibal West	9.6 Exceptional 1,000 reviews	View
River's Edge Motel	9.0 Wonderful 390 reviews	View
The Eagles Nest Inn	9.4 Exceptional 26 reviews	View
Best Western On The River	8.6 Excellent 1,007 reviews	View
Riverside Inn Hannibal	9.6 Exceptional 199 reviews	View

Other landmarks near Mississippi River

Mark Twain Cave

8.8/10 (89 reviews)

If you're planning a bit of sightseeing during your trip, head to Mark Twain Cave— just one of the landmarks located 3.3 mi (5.4 km) from central Hannibal.

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Sawyer's Creek Fun Park

7.8/10 (16 reviews)

Sawyer's Creek Fun Park is 3.3 mi (5.3 km) from central Hannibal, why not stop by during your stay. Our travelers also like this walkable area for its restaurants. Want to stretch your legs some more? Head to Sodalis Nature Preserve, located nearby.

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Lovers Leap

8.8/10 (171 reviews)

You might want to get your camera out and head to Lovers Leap— just one of the landmarks located 2.4 mi (3.9 km) from central Hannibal.

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Sodalis Nature Preserve

Sodalis Nature Preserve is 1.5 mi (2.4 km) from central Hannibal, why not stop by during your stay. Want to stretch your legs some more? Head to Sawyer's Creek Fun Park, located nearby.

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Bluff City Theater

7.6/10 (5 reviews)

Bluff City Theater is 2.1 mi (3.4 km) from central Hannibal, why not stop by during your stay. If you enjoy the show and want to see another, Planters Barn Theater is just a short walk away.

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Planters Barn Theater

8.8/10 (22 reviews)

Planters Barn Theater is 2.1 mi (3.4 km) from central Hannibal, why not stop by during your stay. If you enjoy the show and want to see another, Bluff City Theater is just a short walk away.

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Mark Twain Boyhood Home and Museum

9.0/10 (278 reviews)

If seeing the sights is on your list of things to do, head to Mark Twain Boyhood Home and Museum— just one of the landmarks located 2.1 mi (3.3 km) from central Hannibal.

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Jim's Journey: The Huck Finn Freedom Center

8.4/10 (33 reviews)

If museums are on your list of things to see in Hannibal, then you might want to head to Jim's Journey: The Huck Finn Freedom Center. If you want to see more of the museums in Hannibal, you can easily walk to Mark Twain Boyhood Home and Museum or Molly Brown Museum and Home.

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