Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Southeast Minnesota, MN
Enjoy the collegiate vibe when you visit Winona State University, during your trip to Winona. Stroll along the riverfront or experience the area's museums.
Commune with nature and explore the great outdoors at Forestville Mystery Cave State Park during your travels in Preston. Wander the parks or discover the area's countryside.
Commune with nature and explore the great outdoors at Niagara Cave during your travels in Harmony. Amble within the natural setting or visit the churches in this family-friendly area.
Southeast Minnesota is well-known for its sports and riverfront, featuring attractions such as Mayowood Mansion and Apache Mall. Visitors to this family-friendly city speak highly of the restaurants whereas sights include Plummer House and Soldiers Field Veterans Memorial.
Check out reviews of Southeast Minnesota hotels guests love
Country Inn & Suites Rochester South Mayo Clinic
10/10 Excellent
"You’re basic motel room everything is clean and neat. Lots of towels everything you need soap Dishoom towels, washcloth everything’s here. Great room. I’ll stay again if I’m coming back."
"Loved all the hard surfaces. Everything was very clean, and our room was freshened up each day. The location is perfect for our Mayo appointments and close to a lot of restaurant options. We will definitely be returning!"
Can I book a refundable hotel in Southeast Minnesota?
If you need the flexibility to change your travel plans to Southeast Minnesota, most properties offer refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Southeast Minnesota if I want a vacation home instead of a traditional hotel?
If you want a good alternative to a hotel, browse our selection of 359 vacation homes. In addition, there are 96 apartments and 47 condos.
Why should I book my Southeast Minnesota accommodation with Hotels.com?
There are plenty of reasons to book your Southeast Minnesota travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.
