Hotels in Sanctuary

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Where to stay in Sanctuary?

A resort with a central pool, multiple lounge areas, and a beach view.

A covered porch with a view of the sea, a white railing, and two Adirondack chairs.

A table set for dining with a view of the sunset over the ocean.

A sandy pathway leading to a beach with palm trees and a clear sky.

1. Tween Waters Island Resort & Spa

3.7 km from Sanctuary

Nicholas J

$251

$315 total

includes taxes & fees

Oct 6 - Oct 7

A beachfront hotel with a central entrance, outdoor seating, and palm trees.

A beach with palm trees, string lights, and beach chairs.

A restaurant with multiple tables and chairs, large windows with a view of the ocean, and hanging pendant lights.

A beachside restaurant with outdoor seating, a pool area, and palm trees.

2. South Seas

5.5 km from Sanctuary

Jarrett

$216

$359 total

includes taxes & fees

Oct 8 - Oct 9

A beach with a view of the ocean and a sunset.

A covered outdoor area with a table and chairs, a ceiling fan, and a view of a beach with palm trees and a boat.

A multi-story hotel with a central entrance, balconies, and palm trees.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, and a dining area with white chairs and a table.

3. Island Inn

West End, 9.6 km from Sanctuary

Andrew

$202

$225 total

includes taxes & fees

Oct 5 - Oct 6

A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.

A modern kitchen with grey cabinets, a stainless steel refrigerator, a microwave, and a sink. There is a painting of a flamingo on the wall.

A beachfront hotel with palm trees, a sandy walkway, and a pool.

A resort with a pool, thatched umbrellas, and palm trees.

4. Off the Charts Inn & Out Island Resort

8.8 km from Sanctuary

Catherine

$135

$184 total

includes taxes & fees

Oct 5 - Oct 6

A beach with a variety of seashells and pebbles.

A hammock between palm trees with a view of the ocean.

A landscaped area with palm trees and a view of the ocean.

A hotel room with a bed, a view of the beach, and a window with curtains.

5. Sanibel Island Beach Resort

Mid Island, 13.1 km from Sanctuary

Jennifer

$179

$227 total

includes taxes & fees

Oct 4 - Oct 5

A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

A modern lobby with a white brick wall, a flat-screen TV, and colorful abstract paintings. There are several seating areas with different styles of chairs.

A reception area with a beach view mural, a staircase, and a reception desk.

A modern lobby with a fireplace, seating area, and artwork.

6. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

19.9 km from Sanctuary

Carol

$80

$89 total

includes taxes & fees

Oct 8 - Oct 9

A balcony with a table and chairs, large windows, and a view of the sea.

An outdoor seating area with round tables and pink cushions, palm trees, and string lights against a twilight sky.

A spacious living area with a high ceiling, a ceiling fan, a pool table, and a view of the outdoors.

A swimming pool with clear blue water, surrounded by lounge chairs and umbrellas, and a building with a tiled roof.

7. The Westin Cape Coral Resort At Marina Village

18.1 km from Sanctuary

jessica

$146

$208 total

includes taxes & fees

Oct 25 - Oct 26

A kitchen with white cabinets, a microwave, a sink, and a green refrigerator.

8. The Anchor Inn

Mid Island, 12.8 km from Sanctuary

Daniel

$142

$174 total

includes taxes & fees

Oct 8 - Oct 9

A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

A resort pool area with a large pool, lounge chairs, and umbrellas.

A spacious lobby with a staircase, large windows, and a chandelier.

A table set for two on a beach with a view of the sea and distant islands.

9. Marriott Sanibel Harbour Resort & Spa

15.6 km from Sanctuary

Matthew

$223

$284 total

includes taxes & fees

Oct 15 - Oct 16

A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

A reception desk with a wooden panel design, a welcome sign for 'Sunshine State', and a motivational rug on the floor.

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and artwork on the walls.

A grocery store with shelves stocked with snacks, beverages, and dairy products.

10. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

22.9 km from Sanctuary

Elines

$77

$86 total

includes taxes & fees

Oct 8 - Oct 9

A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

A hotel lobby with a reception desk, seating area, and a large window.

A hotel room with two beds, a large mirror, and a view of the outdoors.

A modern hotel room with a large bed, two armchairs, a small side table with a lamp, and a large window with blinds.

11. Residence Inn by Marriott Fort Myers Sanibel

19.3 km from Sanctuary

nydeshwia

$94

$105 total

includes taxes & fees

Oct 5 - Oct 6

A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.

A well-maintained garden with a wooden deck, palm trees, and a building in the background.

A wooden pathway leading to a beach with a clear view of the ocean.

A resort pool area with a clear view of the ocean, surrounded by palm trees and lounge chairs.

12. Casa Ybel Resort

Ybel, 11.6 km from Sanctuary

Juan

$288

$321 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

A swimming pool with lounge chairs and palm trees.

A modern reception desk with a digital display, a cash register, and a customer service counter.

A Holiday Inn Express & Suites building with a parking lot, a covered entrance, and a landscaped area with flowers.

13. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

23.1 km from Sanctuary

Phillip

$84

$94 total

includes taxes & fees

Oct 5 - Oct 6

A pathway flanked by palm trees and wooden buildings with thatched roofs.

A hotel room with a bed, a television, a desk, a chair, and a ceiling fan.

A thatched-roof structure with outdoor seating, surrounded by palm trees and a wooden deck.

A clear blue pool with lounge chairs and umbrellas, surrounded by palm trees and a thatched-roof structure.

14. Kona Kai Motel

Mid Island, 12.2 km from Sanctuary

Paloma

$179

$206 total

includes taxes & fees

Oct 5 - Oct 6

A modern kitchen with white cabinetry, a built-in microwave, a stove, and wooden shelves above holding glassware and a plant.

15. Fountain Cottages Inn

24.2 km from Sanctuary

Just

$33

$67 total

includes taxes & fees

Oct 21 - Oct 22

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

A room with a large aquarium, a dining table with chairs, a refrigerator, and a wall-mounted TV displaying a resort advertisement.

A swimming pool with a thatched roof overhead, surrounded by lounge chairs and a covered patio area.

A marina with rows of blue Adirondack chairs under turquoise umbrellas, wooden docks, and boats.

16. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

21.5 km from Sanctuary

Jorge

$92

$102 total

includes taxes & fees

Oct 4 - Oct 5

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

A kitchen with white cabinets, a microwave, and a sink. There are two white chairs and a table.

An outdoor dining area with thatched roofs and string lights, surrounded by tropical plants.

A hotel room with a bed, a sofa, a dining table with chairs, and a view of the sea through the window.

17. The Lighthouse Resort Inn & Suites

21.5 km from Sanctuary

Cody

$103

$135 total

includes taxes & fees

Oct 4 - Oct 5

A turquoise building with a red door, surrounded by potted plants and flowers.

A bedroom with a bed, a nightstand, a painting, and a window with blinds.

A patio area with outdoor seating, a grill, and a view of a building with large windows.

A person sitting on a sandy beach with the ocean in the background.

18. Angler's Inn

18.8 km from Sanctuary

Cindy

$111

$213 total

includes taxes & fees

Oct 13 - Oct 14

A beachside area with colorful beach houses, a dock, and a sandy beach.

A compact kitchen with a built-in seating area, a refrigerator, and a ceiling fan.

A wooden deck with picnic tables and chairs, a pool, and buildings in the background.

A kitchen with white cabinets, a granite countertop, and a coffee maker.

19. Matlacha Tiny Village

18.8 km from Sanctuary

PETER

$147

$239 total

includes taxes & fees

Oct 3 - Oct 4

A modern hotel lobby with a seating area, a reception desk, and a dining area.

A Hampton Inn & Suites hotel entrance with a 'Welcome' sign, palm trees, and a well-lit facade.

A modern hotel room with a flat-screen TV mounted on a wooden console, a microwave, a small sink, and a yellow chair.

A hotel room with a bed, a desk, a chair, a TV, and a mirror.

20. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

22.6 km from Sanctuary

Amy

$94

$105 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Our prices for hotels in Sanibel are cheapest in October

Check out reviews of Sanctuary hotels guests love

Sanibel Island Beach Resort

10/10 Excellent

"We spent 4 days in Sanibel and this resort was everything. Walking distance to the beach, nice pool and bar area, clean, the restaurant had great food too. We were also able to check in a little early which was really helpful for us. Will definitely be back!!"

Hilton Garden Inn Ft Myers

10/10 Excellent

"Excellent property!"

DiamondHead Beach Resort

10/10 Excellent

"Every thing was amazing"

Sundial Beach Resort & Spa

10/10 Excellent

"Tiki bar and restaurants were excellent and very good prices for excellent food. All staff were so helpful. So much to do. Rooms were spacious and comfy"

The Bay Inn at Lani Kai

10/10 Excellent

"Clean room, helpful staff, very close to the beach."

Residence Inn by Marriott Fort Myers Sanibel

10/10 Excellent

"Great location, clean, delicious breakfast. A+."

The Westin Cape Coral Resort At Marina Village

10/10 Excellent

"My husband and I chose this resort as our monthly get away. It is the sister hotel of the Currant Hotel. Our stay was very pleasurable and relaxing. This was our first stay here. I had read the reviews prior to staying here, and of course everyone cannot be pleased. I would suggest for younger couples with small children, that this resort isn't very child friendly due to not seeing any amenities for small children, teenagers will be fine. Our valet attendant who was a middle-aged Middle Eastern gentleman was absolutely amazing! This man truly valued his job. He stated he had been working for around eight months, and that his son was also an employee at the Resort. The food was decent, but I didn't understand how they would allow the restaurant to run out of shrimp on a Saturday at 1 p.m. The drinks were also good, not to strong, but worth the money. The only concern that I do have, is that housekeeping tried to enter our room after the doorbell was rang, but we had the latch lock on. When we opened the door there was no one there, and we didn't see a housekeeping cart or anything. I was left wondering who trying to get into our room being a key was used. My husband called the front desk and informed them what had happened. They promised to check into the inquiry and call back. The front desk called and confirmed that it was a housekeeper who badge showed that she/he had swiped our room door. Why would she come into our room if she didn't have any supplies."

Marriott Sanibel Harbour Resort & Spa

10/10 Excellent

"Super"

Edison Beach House

10/10 Excellent

"The Edison Beach House is a fabulous place to stay. A spacious room, friendly staff and gorgeous location made our vacation special."

Find out more about Sanctuary

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Hotels in Sanctuary

Room 1

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Sanctuary?

1. Tween Waters Island Resort & Spa

2. South Seas

3. Island Inn

4. Off the Charts Inn & Out Island Resort

5. Sanibel Island Beach Resort

6. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

7. The Westin Cape Coral Resort At Marina Village

8. The Anchor Inn

9. Marriott Sanibel Harbour Resort & Spa

10. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

11. Residence Inn by Marriott Fort Myers Sanibel

12. Casa Ybel Resort

13. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

14. Kona Kai Motel

15. Fountain Cottages Inn

16. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

17. The Lighthouse Resort Inn & Suites

18. Angler's Inn

19. Matlacha Tiny Village

20. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Typical weather for Sanibel

Check out reviews of Sanctuary hotels guests love

Sanibel Island Beach Resort

Hilton Garden Inn Ft Myers

DiamondHead Beach Resort

Sundial Beach Resort & Spa

The Bay Inn at Lani Kai

Residence Inn by Marriott Fort Myers Sanibel

The Westin Cape Coral Resort At Marina Village

Marriott Sanibel Harbour Resort & Spa

Edison Beach House

Keep exploring

Hotels in Sanctuary

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Sanctuary?

1. Tween Waters Island Resort & Spa

2. South Seas

3. Island Inn

4. Off the Charts Inn & Out Island Resort

5. Sanibel Island Beach Resort

6. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

7. The Westin Cape Coral Resort At Marina Village

8. The Anchor Inn

9. Marriott Sanibel Harbour Resort & Spa

10. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

11. Residence Inn by Marriott Fort Myers Sanibel

12. Casa Ybel Resort

13. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

14. Kona Kai Motel

15. Fountain Cottages Inn

16. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

17. The Lighthouse Resort Inn & Suites

18. Angler's Inn

19. Matlacha Tiny Village

20. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Price trends for hotels in Sanibel

Typical weather for Sanibel

Check out reviews of Sanctuary hotels guests love

Sanibel Island Beach Resort

Hilton Garden Inn Ft Myers

DiamondHead Beach Resort

Sundial Beach Resort & Spa

The Bay Inn at Lani Kai

Residence Inn by Marriott Fort Myers Sanibel

The Westin Cape Coral Resort At Marina Village

Marriott Sanibel Harbour Resort & Spa

Edison Beach House

Keep exploring