Hotels in Sanctuary

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Tonight
Sep 22 - Sep 23
Tomorrow
Sep 23 - Sep 24
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Where to stay in Sanctuary?

A resort with a central pool, multiple lounge areas, and a beach view.
A table set for dining with a view of the sunset over the ocean.
A covered porch with a view of the sea, a white railing, and two Adirondack chairs.
A sandy pathway leading to a beach with palm trees and a clear sky.

1. Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.7 km from Sanctuary
United States
Nicholas J
$279
$346 total
includes taxes & fees
Sep 28 - Sep 29
Tween Waters Island Resort & Spa
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.
A swimming pool area with lounge chairs, a small building, and a basketball court surrounded by palm trees and greenery.
A hotel room with two beds, a large mirror, and a view of the outdoors.
A modern hotel room with a large bed, two armchairs, a small side table with a lamp, and a large window with blinds.

2. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
19.3 km from Sanctuary
United States
nydeshwia
$86
$96 total
includes taxes & fees
Sep 24 - Sep 25
Residence Inn by Marriott Fort Myers Sanibel
A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.
A bedroom with a large bed, a desk, and a chair. There is a sliding barn door and a painting of a beach on the wall.
A beachfront hotel with palm trees, a sandy walkway, and a pool.
A modern kitchen with grey cabinets, a stainless steel refrigerator, a microwave, and a sink. There is a painting of a flamingo on the wall.

3. Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
8.8 km from Sanctuary
United States
Catherine
$135
$184 total
includes taxes & fees
Sep 28 - Sep 29
Off the Charts Inn & Out Island Resort
A beach with a variety of seashells and pebbles.
A pool area with lounge chairs and a building with a red roof.
A hotel room with a bed, a view of the beach, and a window with curtains.
A landscaped area with palm trees and a view of the ocean.

4. Sanibel Island Beach Resort

Sanibel Island Beach Resort
Mid Island, 13.1 km from Sanctuary
United States
Jennifer
$179
$227 total
includes taxes & fees
Oct 4 - Oct 5
Sanibel Island Beach Resort
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.
A modern lobby with a fireplace, seating area, and artwork.
A reception area with a beach view mural, a staircase, and a reception desk.
A spacious indoor dining area with high ceilings, large windows, and modern orange chairs and white tables.

5. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
19.9 km from Sanctuary
United States
Carol
$71
$79 total
includes taxes & fees
Sep 29 - Sep 30
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
A beachfront hotel with a central entrance, outdoor seating, and palm trees.
A restaurant with multiple tables and chairs, large windows with a view of the ocean, and hanging pendant lights.
A resort pool area with multiple sun loungers and umbrellas, surrounded by palm trees and a view of the ocean.
A beachside restaurant with outdoor seating, a pool area, and palm trees.

6. South Seas

South Seas
5.5 km from Sanctuary
United States
Jarrett
$221
$366 total
includes taxes & fees
Oct 8 - Oct 9
South Seas
A beach with a view of the ocean and a sunset.
A modern living room with a sofa, chairs, and a dining table. There is a kitchen area with cabinets and appliances.
A multi-story hotel with a central entrance, balconies, and palm trees.
A modern kitchen with wooden cabinets, a stainless steel refrigerator, and a dining area with white chairs and a table.

7. Island Inn

Island Inn
West End, 9.6 km from Sanctuary
United States
Andrew
$202
$225 total
includes taxes & fees
Sep 29 - Sep 30
Island Inn
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.
A swimming pool with lounge chairs and palm trees.
A modern reception desk with a digital display, a cash register, and a customer service counter.
A modern indoor space with a large table, chairs, and a television.

8. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
23.1 km from Sanctuary
United States
Phillip
$95
$106 total
includes taxes & fees
Oct 22 - Oct 23
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
A beachside area with colorful Adirondack chairs, a fire pit, and a view of the water.
A modern kitchen with white cabinets, granite countertops, a built-in oven, and a microwave.
A living room with two sofas, a coffee table, a ceiling fan, a TV, and a cabinet.
A bedroom with a large bed, a TV mounted on the wall, two bedside tables with lamps, and a window with blinds.

9. Matlacha on Shoreview

Matlacha on Shoreview
20.2 km from Sanctuary
United States
Jacquelyn
$65
$139 total
includes taxes & fees
Sep 24 - Sep 25
Matlacha on Shoreview
A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.
A marina with rows of blue Adirondack chairs under turquoise umbrellas, wooden docks, and boats.
A room with a large aquarium, a dining table with chairs, a refrigerator, and a wall-mounted TV displaying a resort advertisement.
A swimming pool with a thatched roof overhead, surrounded by lounge chairs and a covered patio area.

10. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
21.5 km from Sanctuary
United States
Jorge
$88
$98 total
includes taxes & fees
Sep 24 - Sep 25
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
A wooden boardwalk leading to a beach with clear skies and calm waters.
A pool area with lounge chairs and umbrellas, a wooden deck, and a view of the beach and ocean.
A resort with multiple buildings featuring blue roofs, a beach, and a clear view of the ocean.
A modern room with a large sliding glass door leading to a balcony with a view of the beach. There is a white sofa, a small table, and a white desk with a chair.

11. Shalimar Beach Resort

Shalimar Beach Resort
West End, 10.3 km from Sanctuary
United States
Martha
$249
$277 total
includes taxes & fees
Sep 27 - Sep 28
Shalimar Beach Resort
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and artwork on the walls.
A grocery store with shelves stocked with snacks, beverages, and dairy products.
A reception desk with a wooden panel design, a welcome sign for 'Sunshine State', and a motivational rug on the floor.

12. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
22.9 km from Sanctuary
United States
Elines
$77
$86 total
includes taxes & fees
Sep 29 - Sep 30
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
A balcony with a wicker sofa, a yellow table, and a potted plant.
A poolside area with lounge chairs, a swimming pool, and a covered seating area with a thatched roof.
A cozy interior with a wooden ceiling, a blue patterned sofa, yellow cushions, a dining area with a table and chairs, and a TV on the wall.
A marina with boats docked, a wooden dock, and a building with balconies.

13. Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
22 km from Sanctuary
United States
Teresa
$111
$123 total
includes taxes & fees
Sep 24 - Sep 25
Latitude 26 Waterfront Resort & Marina
A kitchen with white cabinets, a microwave, a sink, and a green refrigerator.
A boat-shaped deck chair with cushions, positioned on a wooden deck with a white fence.

14. The Anchor Inn

The Anchor Inn
Mid Island, 12.8 km from Sanctuary
United States
Daniel
$148
$180 total
includes taxes & fees
Sep 27 - Sep 28
The Anchor Inn
A hotel room with a large bed, two bedside tables with lamps, a nightstand, and a window with curtains.
A gym with exercise equipment, benches, dumbbells, and a mirror.
A swimming pool with a lifeguard chair, a no diving sign, and a pool rules sign.
A compact kitchen with a wooden table, chairs, a refrigerator, a microwave, and cabinets.

15. Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
25.4 km from Sanctuary
United States
Beatrice
$52
$58 total
includes taxes & fees
Sep 27 - Sep 28
Candlewood Suites Fort Myers Sanibel Gateway by IHG
A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.
A resort pool area with a clear view of the ocean, surrounded by palm trees and lounge chairs.
A well-maintained garden with a wooden deck, palm trees, and a building in the background.
A large, two-story house with a wrap-around porch and a steeply pitched roof.

16. Casa Ybel Resort

Casa Ybel Resort
Ybel, 11.6 km from Sanctuary
United States
Juan
$288
$321 total
includes taxes & fees
Sep 27 - Sep 28
Casa Ybel Resort
A balcony with a pool view, a table, and chairs.
A living room with a black leather sofa, a wooden coffee table, and a dining area with a wooden table and chairs. There is a kitchen area with white cabinets and a refrigerator.
A small, clean room with a dining table, chairs, a washing machine, and a window with blinds.
A hotel room with two beds, a TV, a desk, and a window with blinds.

17. OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
25.2 km from Sanctuary
United States
Gina
$54
$60 total
includes taxes & fees
Oct 6 - Oct 7
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
A balcony with a table and chairs, large windows, and a view of the sea.
A swimming pool with clear blue water, surrounded by lounge chairs and umbrellas, and a building with a tiled roof.
A spacious living area with a high ceiling, a ceiling fan, a pool table, and a view of the outdoors.

18. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
18.1 km from Sanctuary
United States
jessica
$146
$208 total
includes taxes & fees
Oct 1 - Oct 2
The Westin Cape Coral Resort At Marina Village
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.
An outdoor dining area with thatched roofs and string lights, surrounded by tropical plants.
A hotel room with a bed, a sofa, a dining table with chairs, and a view of the sea through the window.
A multi-story hotel with a central atrium, palm trees, and a well-lit exterior.

19. The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
21.5 km from Sanctuary
United States
Cody
$97
$128 total
includes taxes & fees
Sep 30 - Oct 1
The Lighthouse Resort Inn & Suites
A pathway flanked by palm trees and wooden buildings with thatched roofs.
A hotel room with a bed, a television, a desk, a chair, and a ceiling fan.
A thatched-roof structure with outdoor seating, surrounded by palm trees and a wooden deck.
A compact kitchen with a stainless steel refrigerator, a microwave, a coffee maker, and a sink.

20. Kona Kai Motel

Kona Kai Motel
Mid Island, 12.2 km from Sanctuary
United States
Paloma
$179
$206 total
includes taxes & fees
Sep 24 - Sep 25
Kona Kai Motel
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Our prices for hotels in Sanibel are cheapest in October
Price trends for hotels in Sanibel
Pricing is based on two traveler single night rates
View properties in September
Typical weather for Sanibel
September
High 30°C / low 26°C. Partly sunny.
View properties in September
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Monthly weather averages (˚C)

Check out reviews of Sanctuary hotels guests love

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

10/10 Excellent
"It was our first visit since the last devastating hurricane. We were pleased how well the hotel looked and amenities and staff were great. Everyone was friendly and dining at Rae's was outstanding. We are local and will definitely be back"
John 2-night trip
Posted 2 hours ago
Pink Shell Beach Resort and Marina
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

10/10 Excellent
"We had a great time!"
Giovanni 2-night trip
Posted 4 hours ago
The Lighthouse Resort Inn & Suites
Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel

10/10 Excellent
"The room and facility were clean. The staff was friendly and polite. The breakfast was good. I was impressed with the experience."
Alan 2-night trip
Posted 5 hours ago
Residence Inn by Marriott Fort Myers Sanibel
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

10/10 Excellent
"Love the resort and great access to beach"
Lisa Renee 5-night trip
Posted 5 hours ago
Sundial Beach Resort & Spa
DiamondHead Beach Resort

DiamondHead Beach Resort

10/10 Excellent
"The room was very comfortable with a beautiful view of the beach. The staff were very friendly and helpful. Would definitely stay here again."
Rebecca 8-night trip
Posted 6 hours ago
DiamondHead Beach Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

10/10 Excellent
"Was a great stay! Clean rooms, clean property, great amenities, great food, great drinks, amazing atmosphere, fun and engaging entertainment, the sunsets weren't bad either."
Michele 1-night trip
Posted 10 hours ago
Margaritaville Beach Resort Fort Myers
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

8/10 Good
"Front desk staff, Grace and Tyquan were amazing"
Thomas 2-night trip
Posted 15 hours ago
Lani Kai Beachfront Resort
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

8/10 Good
"This was close to our destination and always clean and friendly folks."
Brandon 1-night trip
Posted 1 day ago
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

10/10 Excellent
"Very clean. Breakfast and pool were an added touch! Loved to coffee too!"
Jennifer Marie 1-night trip
Posted 1 day ago
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
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