Hilton Jacksonville At Mayo Clinic

Luxury hotel in Jacksonville with outdoor pool and restaurant

Choose dates to view prices

Where to?

Dates

November 2025

1

December 2025

Breakfast, lunch, dinner served; American cuisine

Premium bedding, in-room safe, blackout drapes, iron/ironing board

When you stay at Hilton Jacksonville At Mayo Clinic, you'll be within a 10-minute drive of Mayo Clinic Florida and St. Johns Town Center. The outdoor pool is a great spot to take a dip, and guests can grab a bite to eat at Coastal Kitchen, which serves American cuisine and is open for breakfast, lunch, and dinner. Other highlights at this luxurious hotel include a fitness center and a bar/lounge.

Exceptional

Popular amenities

Pool
Electric vehicle charging point
Bar
Gym
Free parking
24/7 front desk

Main amenities (12)

Daily housekeeping
Restaurant and bar/lounge
Outdoor pool
Breakfast available
Free area shuttle
Fitness center
Room service
12 meeting rooms
Meeting rooms
24-hour front desk
Air conditioning
Convenience store

For families (6)

Children stay free
Free cribs/infant beds
Premium TV channels
Daily housekeeping
Laundry facilities
Coffee/tea maker

$152 total

includes taxes & fees

Nov 25 - Nov 26

Room options

Check availability for these dates

Tonight

Nov 1 - Nov 2

Tomorrow

Nov 2 - Nov 3

All rooms

1 bed

2 beds

Showing 20 of 20 rooms

Room, 1 King Bed

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 2
1 King Bed

Deluxe Room, 1 King Bed (Water View)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Sofa bed - single

Premium bedding

Blackout drapes/curtains

Water view
Sleeps 2
1 King Bed

Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 2
1 King Bed

Junior Suite, 1 King Bed

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Sofa bed - single

Premium bedding

Blackout drapes/curtains

Sleeps 4
1 King Bed

Junior Suite, 1 King Bed, Corner

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Sofa bed - single

Premium bedding

Blackout drapes/curtains

Sleeps 4
1 King Bed

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 2
1 King Bed

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 2
1 King Bed

Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 2
1 King Bed

Room, 1 King Bed (Zero Count)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 2
1 King Bed

Room, 1 King Bed (Water View)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Water view
Sleeps 2
1 King Bed

Room, 1 King Bed (Water View, Roll-In Shower)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Water view
Sleeps 2
1 King Bed

Room, 1 King Bed, Accessible (Hearing)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 2
1 King Bed

Room, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 2
1 King Bed

Room, 1 King Bed, Accessible (Hearing)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 2
1 King Bed

Room, 2 Queen Beds

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 4
2 Queen Beds

Room, 2 Queen Beds, Accessible (Water View, Hearing)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Water view
Sleeps 4
2 Queen Beds

Room, 2 Queen Beds, Accessible, Bathtub

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 4
2 Queen Beds

Room, 2 Queen Beds, Accessible (Hearing)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 4
2 Queen Beds

Room, 2 Queen Beds (Water View)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Water view
Sleeps 4
2 Queen Beds

Room, 2 Queen Beds, Accessible, Bathtub (View)

Highlights

Air conditioning

Heating

Free cribs/infant beds

Mini-fridge

Smart TV

Premium bedding

Blackout drapes/curtains

Hair dryer

Sleeps 4
2 Queen Beds

Similar properties

On the beach, white sand, surfing, kayaking

Pool
Parking available
Free WiFi
Restaurant

$197 total

includes taxes & fees

Nov 2 - Nov 3

Sign in to view eligible discounts and perks. More rewards for more adventures!

Sign in Sign up, it's free

About the neighborhood

4745 Transformation Way, Jacksonville, FL, 32224

What's nearby

Mayo Clinic Florida - 8 min walk - 0.7 km
University of North Florida - 6 min drive - 9.0 km
St. Johns Town Center - 7 min drive - 10.9 km
Jacksonville Beach Pier - 10 min drive - 10.4 km
TPC Sawgrass - 12 min drive - 14.7 km

Getting around

Jacksonville, FL (CRG-Jacksonville Executive at Craig) - 14 min drive
Jacksonville International Airport (JAX) - 31 min drive
St. Augustine, FL (UST-Northeast Florida Regional) - 40 min drive
Jacksonville Station - 28 min drive
Free area shuttle

Restaurants

‪Culver's #964 - ‬3 min drive
‪M Brothers at Mayo - ‬14 min walk
‪Starbucks - ‬3 min drive
‪Circle K - ‬16 min walk
‪Mayo Clinic - Employee Cafeteria - ‬14 min walk

About this property

Hilton Jacksonville At Mayo Clinic

When you stay at Hilton Jacksonville At Mayo Clinic, you'll be within a 10-minute drive of Mayo Clinic Florida and St. Johns Town Center. The outdoor pool is a great spot to take a dip, and guests can grab a bite to eat at Coastal Kitchen, which serves American cuisine and is open for breakfast, lunch, and dinner. Other highlights at this luxurious hotel include a fitness center and a bar/lounge.

At a glance

Hotel size

- 252 rooms
- Arranged over 8 floors

Arriving/Leaving

- Check-in start time: 4:00 PM; Check-in end time: 5:00 AM
- Express check-out available
- Late check-in subject to availability
- Minimum check-in age: 21
- Check-out time is 11:00 AM
- Contactless check-out available

Special check-in instructions

- Front desk staff will greet guests on arrival at the property
- If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation
- The credit card used to book the reservation must be presented by the cardholder at check-in along with matching photo identification, and other arrangements must be coordinated with the property prior to arrival

Required at check-in

- Credit card required for incidental charges
- Government-issued photo ID may be required
- Minimum check-in age is 21

Children

- Up to 2 children (18 years old and younger) stay free, per registered adult, when occupying the parent or guardian's room, using existing bedding

Pets

- Pets not allowed

Internet

- Free WiFi in public areas
- Free WiFi in rooms (speed: 25+ Mbps)

Parking

- Free uncovered onsite self parking
- Electric vehicle charging point on site

Offsite

- Free area shuttle within 350 yards

Other information

- Smoke-free property

Property amenities

Food and drink

Buffet breakfast (surcharge) each morning 6:00 AM–10:30 AM
Restaurant
Bar/lounge
Room service (late night)

Traveling with children

Children stay free (see details)
Free local shuttle
Grocery/convenience store
Children's menu

Working away

12 meeting rooms
Coworking spaces
Conference space (20000 square feet)

Services

24-hour front desk
Concierge services
Dry cleaning/laundry services
Luggage storage
Wedding services
Porter/bellhop
Pool loungers
Pool umbrellas
Romance packages

Facilities

1 building/tower
Built in 2025
Television in common areas
Fitness center
An outdoor pool
At least 80% of food locally-sourced
Vegetarian dining options
At least 80% lighting from LEDs
Comprehensive food waste policy
Firepit
Outdoor furniture
Traditional architecture

Accessibility

Tile flooring in public areas

Room amenities

Be entertained

55-inch Smart TV
Premium cable channels
Netflix
Streaming services

Home comfort

Air conditioning and heating
Coffee/tea maker
Iron/ironing board

Sleep well

Blackout drapes/curtains
Premium bedding
Free crib/infant bed
Rollaway/extra bed (surcharge)

Freshen up

Bathtub or shower
Soap and shampoo
Hair dryer
Towels
Toilet paper

Stay connected

Free WiFi (speed of 25+ Mbps)
Free long-distance and local calls

Food and drink

Mini-fridge
Free bottled water

More

Daily housekeeping
In-room safe (laptop compatible)
LED light bulbs
Recycling
Water-efficient showers only
Water-efficient toilets only
Mobile key entry
Local maps

Special features

Dining

Coastal Kitchen - This restaurant specializes in American cuisine and serves breakfast, lunch, and dinner. Guests can enjoy drinks at the bar. A children's menu is available.

Coastal Kitchen Bar - Onsite cocktail bar. Open daily.

Fees & policies

Refundable deposits

Breakage deposit: USD 100 per stay

Optional extras

Buffet breakfast is offered for an extra charge of approximately USD 26.99 to 26.99 for adults, and USD 15 to 21 for children

Children & extra beds

Rollaway beds are available for USD 50.00 per night

Pool, spa, & gym (if applicable)

Pool access available from 8:00 AM to 10:00 PM
Guests under 16 years old are not allowed in the fitness facility, and guests under 16 years old are only allowed in the swimming pool with adult supervision

Policies

Only registered guests are allowed in the guestrooms.

Guests can rest easy knowing there's a carbon monoxide detector and a smoke detector on site.

This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation.

This property accepts credit cards and debit cards. Cash is not accepted.

Credit cards accepted: Visa, Mastercard, American Express, Discover, Diners Club, Carte Blanche

Cashless transactions are available.

This property reserves the right to pre-authorize the guest's credit card prior to arrival.

Also known as

Hilton Jacksonville At Mayo Clinic Hotel

Hilton Jacksonville At Mayo Clinic Jacksonville

Hilton Jacksonville At Mayo Clinic Hotel Jacksonville

Frequently asked questions

Is there a pool at Hilton Jacksonville At Mayo Clinic?

Yes, there's an outdoor pool. Guests have pool access from 8:00 AM to 10:00 PM.

Are pets allowed at Hilton Jacksonville At Mayo Clinic?

Sorry, pets aren't allowed.

Is parking offered on site at Hilton Jacksonville At Mayo Clinic?

Yes, there's free self parking. Electric vehicle charging is available.

What are the check-in and check-out times at Hilton Jacksonville At Mayo Clinic?

Check-in start time: 4:00 PM; Check-in end time: 5:00 AM. Check-out time is 11:00 AM. Express check-out and contactless check-out are available.

What is there to do at Hilton Jacksonville At Mayo Clinic and nearby?

Hilton Jacksonville At Mayo Clinic has an outdoor pool and a fitness center.

Are there restaurants at or near Hilton Jacksonville At Mayo Clinic?

Yes, Coastal Kitchen offers American cuisine.

What's the area around Hilton Jacksonville At Mayo Clinic like?

Hilton Jacksonville At Mayo Clinic is located a short 6-minute walk from Mayo Clinic Florida.

Have a question?

Beta

Get instant answers with AI powered search of property information and reviews.

Ask a question

Hilton Jacksonville At Mayo Clinic

Choose dates to view prices

Photo gallery for Hilton Jacksonville At Mayo Clinic

Reviews

Popular amenities

Main amenities (12)

For families (6)

Room options

Check availability for these dates

View all photos for Room, 1 King Bed

Room, 1 King Bed

Highlights

View all photos for Deluxe Room, 1 King Bed (Water View)

Deluxe Room, 1 King Bed (Water View)

Highlights

View all photos for Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)

Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)

Highlights

View all photos for Junior Suite, 1 King Bed

Junior Suite, 1 King Bed

Highlights

View all photos for Junior Suite, 1 King Bed, Corner

Junior Suite, 1 King Bed, Corner

Highlights

View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Highlights

View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Highlights

View all photos for Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)

Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)

Highlights

View all photos for Room, 1 King Bed (Zero Count)

Room, 1 King Bed (Zero Count)

Highlights

View all photos for Room, 1 King Bed (Water View)

Room, 1 King Bed (Water View)

Highlights

View all photos for Room, 1 King Bed (Water View, Roll-In Shower)

Room, 1 King Bed (Water View, Roll-In Shower)

Highlights

View all photos for Room, 1 King Bed, Accessible (Hearing)

Room, 1 King Bed, Accessible (Hearing)

Highlights

View all photos for Room, 1 King Bed, Accessible (Roll-In Shower)

Room, 1 King Bed, Accessible (Roll-In Shower)

Highlights

View all photos for Room, 1 King Bed, Accessible (Hearing)

Room, 1 King Bed, Accessible (Hearing)

Highlights

View all photos for Room, 2 Queen Beds

Room, 2 Queen Beds

Highlights

View all photos for Room, 2 Queen Beds, Accessible (Water View, Hearing)

Room, 2 Queen Beds, Accessible (Water View, Hearing)

Highlights

View all photos for Room, 2 Queen Beds, Accessible, Bathtub

Room, 2 Queen Beds, Accessible, Bathtub

Highlights

View all photos for Room, 2 Queen Beds, Accessible (Hearing)

Room, 2 Queen Beds, Accessible (Hearing)

Highlights

View all photos for Room, 2 Queen Beds (Water View)

Room, 2 Queen Beds (Water View)

Highlights

View all photos for Room, 2 Queen Beds, Accessible, Bathtub (View)

Room, 2 Queen Beds, Accessible, Bathtub (View)

Highlights

Similar properties

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

About the neighborhood

What's nearby

Getting around

Restaurants

About this property

Hilton Jacksonville At Mayo Clinic

At a glance

Hotel size