Hotels in Mesa

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Where to stay in Mesa?

A restaurant interior with wooden beams, antler decorations, and a long wooden bench.

A bedroom with a wooden headboard, a bed with a green bedspread, two bedside tables with lamps, and a small wooden desk with a plant.

A wooden reception desk with a computer monitor, a sign indicating the desk is open, and a wall-mounted light fixture.

A building with a porch, wooden steps, and two large wheels on the facade.

1. Wagon Wheel Restaurant Bar and Motel

Mesa

$170

$179 total

includes taxes & fees

Oct 12 - Oct 13

A hotel with a swimming pool, lounge chairs, and a view of a mountain.

A covered porch with white rocking chairs, a wooden barrel, and a view of a mountain.

A house with a covered porch, a stone wall, and a mountain in the background.

A vineyard estate with multiple buildings, including a large house with a green roof and several smaller structures.

2. Wine Country Inn Palisade

Palisade

$152

$169 total

includes taxes & fees

Nov 1 - Nov 2

A sign for the Spoke and Vine Motel with a bicycle symbol, set against a mountainous backdrop.

A metal cart with shelves holding mugs, a kettle, wine bottles, and fruit.

A dining area with a wooden table and chairs, a patterned rug, and pendant lighting.

A covered outdoor seating area with wooden benches and a round table.

3. Spoke and Vine Motel

Palisade

$152

$169 total

includes taxes & fees

Oct 27 - Oct 28

A rustic cabin with a garage, surrounded by a gravel driveway, a large tree with yellow leaves, and a rocky cliff in the background.

A rustic building with a red exterior and white walls, a gravel driveway, and a large tree in front.

A modern bedroom with a large bed, a TV mounted on the wall, a bathroom with a shower curtain, and a small seating area with a chair.

A patio with a lounge chair and a table, a tree, and a view of the landscape.

4. The Homestead

Palisade

$207

$218 total

includes taxes & fees

Nov 1 - Nov 2

Two people sitting on chairs outside a building with green doors, one holding a bottle.

A green door with the number 3, two brown chairs, and a potted plant.

A room with a dark blue wall, a brown sofa, a wicker chair, a small side table with a plant, and a hanging macrame piece.

A room with a sofa, a dining table, chairs, a potted plant, a wall-mounted plant, and a framed picture.

5. The Alpine Motel

Collbran

$122

$131 total

includes taxes & fees

Oct 12 - Oct 13

A wooden deck with a view of a forest and a lake.

Two wooden cabins surrounded by a snowy forest.

A rustic interior with a wooden dining table, a striped armchair, a gray sofa, and a wooden cabinet.

A cozy cabin interior with a wooden dining table, a sofa, and a kitchen area including a stove and cabinets.

6. Grand Mesa Lodge

Cedaredge

$122

$133 total

includes taxes & fees

Nov 1 - Nov 2

A wooden deck with a table and chairs, a stone wall, and a view of a lake surrounded by trees.

A long wooden table with a polished surface, surrounded by chairs, in a rustic room with wooden walls and a brick fireplace.

A wooden cabin room with two beds, a small desk, and a stone archway.

A log cabin with large windows, surrounded by snow.

7. Alexander lake lodge

Cedaredge

$113

$122 total

includes taxes & fees

Oct 25 - Oct 26

A spacious living area with a high ceiling, a wooden coffee table, a leather sofa, and a staircase leading to an upper level.

A spacious living room with a stone fireplace, a leather sofa, a desk with a computer, and a large mirror.

A hotel room with a large bed, a TV, a dresser, and a door.

An indoor swimming pool with clear water, a 3-foot depth marker, and a lifeguard stand.

8. Best Western Grande River Inn & Suites

Clifton

$110

$117 total

includes taxes & fees

Oct 26 - Oct 27

A parking lot with a red SUV, a blue truck, and a white car.

A hotel room with a bed, a desk, a television, and a window with curtains.

A hotel room with a wooden dining table, chairs, a TV, a desk, and a window with curtains.

A gym with treadmills, weight machines, and exercise balls.

9. Western Slope suites

Parachute

$72

$81 total

includes taxes & fees

Nov 1 - Nov 2

A restaurant with stone walls and large windows, outdoor wooden tables and chairs, and a garden with colorful flowers.

An indoor swimming pool with a mural of a desert landscape, a ceiling with skylights, and a seating area with chairs.

A bar area with a wooden interior, bar stools, and a sign for Cook's Goldblume beer.

A dining area with a wooden table and chairs, a kitchen counter with various items, and a view of trees through large windows.

10. Grand Vista Hotel

Horizon Drive District

$79

$91 total

includes taxes & fees

Nov 1 - Nov 2

A rustic interior with a staircase, wooden beams, and potted plants.

A modern building with large windows, a staircase, and a solar panel.

A stone-floored patio with a bed, a chair, and a table.

A room with a bed, a desk, a chair, a table, and a view through a glass door to the outside.

11. Maison de Terre

Cedaredge

$140

$179 total

includes taxes & fees

Oct 12 - Oct 13

A reception desk at the Grand River Hotel with a stone wall backdrop and a large illuminated sign.

An indoor swimming pool with clear water, a red lounge chair, and a tiled floor.

A cozy living room with a fireplace, leather sofa, and horse-themed artwork.

A Grand River Hotel with a modern design, featuring a prominent entrance and a parking lot.

12. Grand River Hotel

Parachute

$65

$74 total

includes taxes & fees

Nov 1 - Nov 2

A reception desk with a clock, a computer, and a potted plant.

A modern living room with a fireplace, red leather chairs, a glass coffee table, and a large window with a mountain view.

A corridor with tiled flooring, several round tables with chairs, and a black refrigerator.

A modern office space with a desk, office chair, and a large landscape painting on the wall.

13. Ramada by Wyndham Grand Junction

Horizon Drive District

$77

$88 total

includes taxes & fees

Nov 1 - Nov 2

A reception area with a wooden reception desk, a framed welcome sign, and a no-smoking sign.

A clean, modern dining area with a wooden counter and chairs.

A rectangular swimming pool with a blue tiled edge, surrounded by white lounge chairs and a metal fence.

A hotel room with two beds, a nightstand with a lamp, and two framed pictures on the wall.

14. Super 8 by Wyndham Grand Junction Colorado

Horizon Drive District

$60

$68 total

includes taxes & fees

Nov 8 - Nov 9

A large indoor swimming pool with a hot tub, surrounded by lounge chairs and a tiled floor.

An outdoor patio with stone walls, wooden benches, and a fire pit.

A Grand Vista Hotel with a covered entrance, multiple windows, and a well-lit facade.

A hotel room with a large bed, two bedside tables with lamps, a window with curtains, and a view of mountains.

15. Grand Vista Hotel Parachute

Parachute

$77

$88 total

includes taxes & fees

Nov 1 - Nov 2

16. Camp Eddy

Pear Park

$60

$123 total

includes taxes & fees

Nov 9 - Nov 10

A hotel room with two beds, a nightstand with a lamp, framed pictures on the wall, and an air conditioning unit.

A hotel room with a green sofa, a small table with a lamp, a phone, a mirror, and a red carpeted floor.

A spacious room with a large window, a red armchair, a wooden desk, and a lamp.

A hotel room with a bed, a desk with a computer, a mirror, a lamp, and a telephone.

17. Quality Inn Grand Junction near University

Horizon Drive District

$80

$92 total

includes taxes & fees

Nov 2 - Nov 3

A breakfast bar with a variety of food items, including fruits, pastries, and dairy products.

A hotel room with two beds, a desk, and a window with curtains.

A modern lounge area with a leather sofa, two patterned side tables, a flat-screen TV mounted on a textured wall, and a built-in fireplace.

A reception area with a large mural of a desert landscape, two reception desks with modern design, and a patterned wall to the left.

18. La Quinta Inn & Suites by Wyndham Grand Junction

Horizon Drive District

$89

$102 total

includes taxes & fees

Nov 10 - Nov 11

A spacious living area with a staircase, two grey armchairs, a round coffee table, and a view of the outside.

A hotel room with a large bed, a desk, a chair, a small table, and a wall-mounted heater.

A spacious dining area with multiple tables and chairs, a kitchen in the background, and a modern ceiling design.

A kitchen with a granite countertop, wooden cabinets, and a stone accent wall.

19. Comfort Inn Grand Junction I-70

Horizon Drive District

$81

$93 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor dining area with orange chairs and tables, a glass railing, and a view of the cityscape through large windows.

A breakfast station with yogurt and oatmeal dispensers, a coffee machine, and a sign advertising 'Top T Breakfast'.

A modern lounge area with blue and purple seating, round tables, and unique pendant lighting.

20. Tru by Hilton Grand Junction Downtown

Historic Grand Junction

$98

$112 total

includes taxes & fees

Nov 8 - Nov 9

View all properties

Go beyond your typical stay in Mesa

Pet friendly

Hot tub

Pool

Cottage

Family friendly

Our prices for hotels in Mesa are cheapest in September

Top landmarks in Mesa

Powderhorn Resort

8.6/10 (106 reviews)

Skiers and snowboarders might want to test out the slopes at Powderhorn Resort, a skiing spot located 6.7 mi (10.8 km) from central Mesa.

See properties

Learn more about Mesa

Mesa is well-known for its attractions such as Powderhorn Resort and Grand Mesa National Forest.

See all hotels in Mesa

A leafless tree on a rocky hillside with a vast landscape in the background.

Check out reviews of Mesa hotels guests love

Quality Inn Grand Junction near University

8/10 Good

"Comfortable."

Ramada by Wyndham Grand Junction

8/10 Good

"Nice, clean rooms and quiet, friendly staff and a great breakfast. I stay here every time I’m in Grand Junction."

Grand River Hotel

10/10 Excellent

"Nice hotel for the price."

Super 8 by Wyndham Grand Junction Colorado

10/10 Excellent

"The outdoor pool was super clean w/sparkling water & open even in early Oct. while it says it’s heated pool, it is not a heated pool but gets warmed from the sun. This was a fantastic place when traveling w/kids! Used the laundry but couldn’t get the coin to drop & they took care of it for us. Took less than an hr to wash & dry. Vending machine didn’t give any issues! More than 5 ⭐️ if I could rate it as the beds were super comfy & the fridge was cold! Thank you for a great experience!"

Western Slope suites

10/10 Excellent

"Staff was very friendly, room were fine"

Ville 718

8/10 Good

"Older hotel but very clean. Nice location close to airport. Everyone was friendly and helpful. We stayed there twice during our trip, our first night in Grand Junction and our last night before flying home. I would stay again."

Frequently asked questions

What accommodations do travelers like in Mesa?

Guests like Wagon Wheel Restaurant Bar and Motel and Powderhorn Lodging.

Can I book a refundable hotel in Mesa?

If you need the flexibility to change your travel plans to Mesa, most properties offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Mesa if I want a vacation home instead of a hotel?

Browse 10 vacation homes on our site. You can also book one of the 13 cabins for your stay.

What will the weather in Mesa be like during my vacation?

July and August are typically the warmest months in Mesa when the average temp is 69°F. January and December are the coldest months when the average temperature is 27°F. March and December are the months with the most rain.

Why should I book my Mesa hotel with Hotels.com?

There are lots of reasons to book your Mesa trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

More ways to book

Book Hotels in Mesa on Hotels.com

Hotels in Mesa

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Mesa?

1. Wagon Wheel Restaurant Bar and Motel

2. Wine Country Inn Palisade

3. Spoke and Vine Motel

4. The Homestead

5. The Alpine Motel

6. Grand Mesa Lodge

7. Alexander lake lodge

8. Best Western Grande River Inn & Suites

9. Western Slope suites

10. Grand Vista Hotel

11. Maison de Terre

12. Grand River Hotel

13. Ramada by Wyndham Grand Junction

14. Super 8 by Wyndham Grand Junction Colorado

15. Grand Vista Hotel Parachute

16. Camp Eddy

17. Quality Inn Grand Junction near University

18. La Quinta Inn & Suites by Wyndham Grand Junction

19. Comfort Inn Grand Junction I-70

20. Tru by Hilton Grand Junction Downtown

Go beyond your typical stay in Mesa

Price trends for hotels in Mesa

Typical weather for Mesa

Top landmarks in Mesa

Powderhorn Resort

Learn more about Mesa

Check out reviews of Mesa hotels guests love

Quality Inn Grand Junction near University

Ramada by Wyndham Grand Junction

Grand River Hotel

Super 8 by Wyndham Grand Junction Colorado

Western Slope suites

Ville 718

Frequently asked questions

Keep exploring