Hotels in De Soto

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Oct 27 - Oct 28
Tomorrow
Oct 28 - Oct 29
This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Where to stay in De Soto?

A compact room with two beds, a kitchenette, and a TV mounted on the wall.

1. Scenic Valley Motel

Scenic Valley Motel
2.0 star property
Lansing
8.2 out of 10, Very good, (154 reviews)
This cozy motel sits just 5 minutes from the magnificent Mississippi River. Nearby Mount Hosmer Park and Lansing City Library offer local exploration while complimentary WiFi and convenient parking enhance your stay.
The price is $59
$86 total
includes taxes & fees
Oct 28 - Oct 29
Scenic Valley Motel
A wooden reception desk with a clock and a 'No Smoking' sign.

2. Boarders Inn & Suites by Cobblestone Hotels – Waukon

Boarders Inn & Suites by Cobblestone Hotels – Waukon
3.5 star property
Waukon
8.0 out of 10, Very good, (513 reviews)
Escape to this welcoming hotel with free daily continental breakfast and complimentary WiFi and parking. Clean rooms provide a comfortable base for exploring the area, while the friendly staff ensures a pleasant, hassle-free stay in this convenient Waukon location.
The price is $89
$100 total
includes taxes & fees
Oct 28 - Oct 29
Boarders Inn & Suites by Cobblestone Hotels – Waukon
A hotel room with two beds, a nightstand with a phone and a lamp, and a carpeted floor.

3. AmericInn by Wyndham Viroqua

AmericInn by Wyndham Viroqua
3.0 star property
Viroqua
8.2 out of 10, Very good, (416 reviews)
Tranquil retreat in Viroqua offering free continental breakfast, WiFi, and parking. This hotel provides a convenient base for exploring nearby Viroqua Country Club and Sidie Hollow Park. Business travelers appreciate the friendly amenities and La Crosse Airport is just 56 minutes away.
The price is $90
$103 total
includes taxes & fees
Nov 1 - Nov 2
AmericInn by Wyndham Viroqua
A room with two wooden beds, a carpeted floor, and wooden paneling on the walls.

4. Sportsmen Motel

Sportsmen Motel
2.0 star property
Dorchester
8.8 out of 10, Excellent, (74 reviews)
Tranquil accommodations in Dorchester featuring complimentary WiFi and convenient self parking. Unwind with Netflix in your room after exploring nearby attractions. La Crosse Municipal Airport is just a 48-minute drive away.
The price is $64
$94 total
includes taxes & fees
Oct 28 - Oct 29
Sportsmen Motel
A hotel room with two beds, a nightstand, a lamp, and two paintings on the wall.

5. MIDWAY MOTEL

MIDWAY MOTEL
2.5 star property
Viroqua
8.2 out of 10, Very good, (76 reviews)
Located along the route in Viroqua, this budget-friendly motel offers free WiFi and parking with 24-hour front desk assistance. Nearby attractions include Viroqua Country Club and Sidie Hollow Park for outdoor enthusiasts.
The price is $100
$111 total
includes taxes & fees
Oct 28 - Oct 29
MIDWAY MOTEL
A hotel entrance with a covered walkway, cars parked outside, and a clear sky.

6. Gundersen Hotel & Suites

Gundersen Hotel & Suites
2.5 star property
Powell-Poage-Hamilton
9.2 out of 10, Wonderful, (1,015 reviews)
This business-friendly hotel offers a convenient indoor pool and 24-hour fitness center near La Crosse Center and City Brewery. Enjoy free breakfast, WiFi, and parking while exploring the Mississippi River area. Fellow travelers praise the helpful staff.
The price is $88
$102 total
includes taxes & fees
Nov 8 - Nov 9
Gundersen Hotel & Suites
A modern kitchen with dark cabinetry, a dining area with a table and chairs, and a hallway with a decorative rug.

7. Tobacco Warehouse Inn

Tobacco Warehouse Inn
3.0 star property
Soldiers Grove
9.6 out of 10, Exceptional, (50 reviews)
This restored warehouse hotel sits along the Kickapoo River, where kayaking and mountain biking await. After exploring nearby trails, return for an in-room massage or relax on the grounds with complimentary WiFi.
The price is $255
$282 total
includes taxes & fees
Oct 28 - Oct 29
Tobacco Warehouse Inn
A hotel reception area with a glass door, a clock, and a welcome sign.

8. Welch Motel

Welch Motel
2.5 star property
La Crosse
7.2 out of 10, Good, (336 reviews)
Escape to this welcoming motel where free WiFi and parking make exploring La Crosse simple. Just a short drive from La Crosse Center and Mississippi River, with 24-hour assistance from the highly praised staff.
The price is $55
$63 total
includes taxes & fees
Nov 8 - Nov 9
Welch Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Go beyond your typical stay in De Soto

pet friendly image
Pet friendly
Pet friendly
hot tub image
Hot tub
Hot tub

Learn more about De Soto

The region around De Soto is home to attractions such as Mississippi River and Mount Hosmer Park.

See all hotels in De Soto
A riverbank with rocks and a tree, a bridge with lights, and a sunset sky.

Check out reviews of De Soto hotels guests love

A room with two wooden beds, a carpeted floor, and wooden paneling on the walls.
Sportsmen Motel

Sportsmen Motel

Sportsmen Motel
Dorchester

10/10 Exceptional

This place is amazing! Comfy beds! Will definitely stay here again.
United States
Chad
Reviewed October 19, 2026
Sportsmen Motel

Frequently Asked Questions

What hotels do travelers like in De Soto?

Guests like Scenic Valley Motel.

Can I book refundable accommodations in De Soto?

If you need the flexibility to change your travel plans to De Soto, most hotels offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in De Soto if I want a vacation home instead of a hotel?

You'll find 12 vacation homes on our site. You can also book one of the 15 cabins for your stay.

What will the weather in De Soto be like during my visit?

The warmest months in De Soto are usually July and August with an average temp of 68°F. January and February are the chilliest months when the average temp is 24°F. The rainiest months are June and May.

Why should I book my De Soto accommodation with Hotels.com?

There are plenty of reasons to book your De Soto travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.