Hotels in Mesopotamia

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Mesopotamia?

Marriott Corrientes Hotel
Marriott Corrientes Hotel
4.5 star property
Corrientes
10.0 out of 10, Exceptional, (21 reviews)
  • cleanliness
    Luxurious riverside retreat with modern amenities for the traveler seeking comfort.
The price is $143
$143 total
Feb 27 - Feb 28
Marriott Corrientes Hotel
Maran Suites & Towers - Hotel & Spa
Maran Suites & Towers - Hotel & Spa
3.5 star property
Parana
9.0 out of 10, Wonderful, (32 reviews)
  • cleanliness
    Relax in the heart of Parana with a full-service spa and health club amenities.
The price is $103
$103 total
Feb 18 - Feb 19
Maran Suites & Towers - Hotel & Spa
Mayim Hotel Termal & SPA
Mayim Hotel Termal & SPA
3.0 star property
Concordia
9.2 out of 10, Wonderful, (7 reviews)
  • cleanliness
    Lakeside luxury with thermal pools and spa services in Concordia.
The price is $90
$90 total
Feb 23 - Feb 24
Mayim Hotel Termal & SPA
Estancia Iberá
Estancia Iberá
3.0 star property
Mercedes
10.0 out of 10, Exceptional, (1 review)
  • cleanliness
    Take a countryside retreat at this scenic B&B in Mercedes with an outdoor pool.
The price is $135
$135 total
Feb 28 - Mar 1
Estancia Iberá
La Regina Lodge
La Regina Lodge
4.0 star property
Municipo de Itati
The price is $76
$76 total
Feb 12 - Feb 13
La Regina Lodge
Rio Arriba Suites Apartments y Resto
Rio Arriba Suites Apartments y Resto
3.5 star property
Bella Vista
8.6 out of 10, Excellent, (4 reviews)
Rio Arriba Suites Apartments y Resto
Turismo Hotel Casino
Turismo Hotel Casino
2.5 star property
Corrientes
7.4 out of 10, Good, (3 reviews)
The price is $113
$113 total
Mar 3 - Mar 4
Turismo Hotel Casino
Costarenas Hotel & Spa
Costarenas Hotel & Spa
3.5 star property
Colon
8.6 out of 10, Excellent, (60 reviews)
  • cleanliness
    Relax in a serene Colon retreat with indoor and outdoor pools and revitalizing spa.
The price is $117
$117 total
Mar 4 - Mar 5
Costarenas Hotel & Spa
Hathor Concordia
Hathor Concordia
3.0 star property
Concordia
8.6 out of 10, Excellent, (368 reviews)
Hathor Concordia
Bungalows Mexico
Bungalows Mexico
2.5 star property
Concepción del Uruguay
8.8 out of 10, Excellent, (12 reviews)
  • cleanliness
    Kitchenette-equipped cabins minutes from Concepción del Uruguay's top attractions.
The price is $52
$52 total
Mar 2 - Mar 3
Bungalows Mexico
Club Valle Termal Resort
Club Valle Termal Resort
3.0 star property
Federacion
9.2 out of 10, Wonderful, (94 reviews)
  • cleanliness
    Thermal spa getaway with poolside bar and nearby hot springs attractions.
The price is $54
$54 total
Mar 4 - Mar 5
Club Valle Termal Resort
La Alondra Casa De Huéspedes
La Alondra Casa De Huéspedes
4.0 star property
Corrientes
9.2 out of 10, Wonderful, (68 reviews)
  • cleanliness
    Boutique hideaway near Corrientes landmarks with an outdoor pool and poolside bar.
La Alondra Casa De Huéspedes
Agustín 1 Apart
Agustín 1 Apart
4.0 star property
Parana
9.0 out of 10, Wonderful, (4 reviews)
  • cleanliness
    Comfortable urban retreat with espresso makers and premium linens to enjoy.
The price is $90
$90 total
Feb 12 - Feb 13
Agustín 1 Apart
Rincón del Socorro
Rincón del Socorro
3.0 star property
Mercedes
10.0 out of 10, Exceptional, (6 reviews)
  • cleanliness
    Escape to a scenic Argentinian lodge with a refreshing outdoor pool and dining options.
The price is $600
$600 total
Feb 12 - Feb 13
Rincón del Socorro
Donsuites Apart Hotel
Donsuites Apart Hotel
3.0 star property
Corrientes
8.6 out of 10, Excellent, (106 reviews)
  • cleanliness
    Unwind on a scenic rooftop terrace with cityscape views and premium comforts.
The price is $63
$63 total
Feb 12 - Feb 13
Donsuites Apart Hotel
Posada Che Teindy
Posada Che Teindy
2.5 star property
Colonia Carlos Pellegrini
  • cleanliness
    Riverside guesthouse in Colonia Carlos Pellegrini with easy marina access.
The price is $105
$105 total
Feb 12 - Feb 13
Posada Che Teindy
Hotel Rio
Hotel Rio
3.0 star property
Chajarí
8.8 out of 10, Excellent, (11 reviews)
  • cleanliness
    In the heart of Chajarí, this relaxing hotel offers easy access to Termas de Chajarí.
The price is $79
$79 total
Mar 1 - Mar 2
Hotel Rio
Nandereta Lodge
Nandereta Lodge
2.5 star property
Colonia Carlos Pellegrini
The price is $212
$212 total
Feb 20 - Feb 21
Nandereta Lodge
O2 Hotel Gualeguaychú
O2 Hotel Gualeguaychú
2.5 star property
Gualeguaychú
7.6 out of 10, Good, (70 reviews)
  • cleanliness
    Enjoy free WiFi and central location at this modern hotel in Gualeguaychú.
The price is $45
$45 total
Feb 18 - Feb 19
O2 Hotel Gualeguaychú
Intersur Colon
Intersur Colon
3.0 star property
Colón
8.8 out of 10, Excellent, (6 reviews)
  • cleanliness
    Relax in this tranquil retreat along Colon's riverside, perfect for poolside leisure.
The price is $99
$99 total
Feb 24 - Feb 25
Intersur Colon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Get last-minute hotel deals in Mesopotamia and save more

Sign in to unlock great savings.
Showing deals for:Feb 20 - Feb 22
Showing deals for:Mar 12 - Mar 13

You can also stay at hotels with a spa in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mesopotamia

Learn more about Mesopotamia

Notable for its natural beauty, Mesopotamia features attractions such as Termas de Chajarí and Lago de Salto Grande. This romantic city has something for everyone including sights like Termas Federacion Water Park and Termas de Federacion.

Iguazu Falls featuring a waterfall

Check out reviews of Mesopotamia hotels guests love

Frequently asked questions

Why should I book my Mesopotamia hotel through Hotels.com?
There are lots of reasons to book your Mesopotamia trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.