Hotels in Sanctuary

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Check prices for these dates

Tonight
Oct 14 - Oct 15
Tomorrow
Oct 15 - Oct 16
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Where to stay in Sanctuary?

A resort with a central pool, multiple lounge areas, and a beach view.
A sandy pathway leading to a beach with palm trees and a clear sky.
A covered porch with a view of the sea, a white railing, and two Adirondack chairs.
A hotel room with a bed, a desk, a TV, a ceiling fan, and a view of the outdoors.

1. Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.7 km from Sanctuary
United States
Nicholas J
$215
$275 total
includes taxes & fees
Oct 15 - Oct 16
Tween Waters Island Resort & Spa
A beach with a view of the ocean and a sunset.
A covered outdoor area with a table and chairs, a ceiling fan, and a view of a beach with palm trees and a boat.
A modern kitchen with wooden cabinets, a stainless steel refrigerator, and a dining area with white chairs and a table.
A multi-story hotel with a central entrance, balconies, and palm trees.

2. Island Inn

Island Inn
West End, 9.6 km from Sanctuary
United States
Andrew
$204
$228 total
includes taxes & fees
Oct 19 - Oct 20
Island Inn
A beachfront hotel with a central entrance, outdoor seating, and palm trees.
A beach with palm trees, string lights, and beach chairs.
A beachside restaurant with outdoor seating, a pool area, and palm trees.
A restaurant with multiple tables and chairs, large windows with a view of the ocean, and hanging pendant lights.

3. South Seas

South Seas
5.5 km from Sanctuary
United States
Jarrett
$223
$368 total
includes taxes & fees
Oct 25 - Oct 26
South Seas
A beach with a variety of seashells and pebbles.
A hotel room with a bed, a view of the beach, and a window with curtains.
A landscaped area with palm trees and a view of the ocean.
A pool area with lounge chairs and a building with a red roof.

4. Sanibel Island Beach Resort

Sanibel Island Beach Resort
Mid Island, 13.1 km from Sanctuary
United States
Kathleen
$179
$227 total
includes taxes & fees
Oct 15 - Oct 16
Sanibel Island Beach Resort
A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.
A resort with a pool, thatched umbrellas, and palm trees.
A beachfront hotel with palm trees, a sandy walkway, and a pool.
A bedroom with a large bed, a desk, and a chair. There is a sliding barn door and a painting of a beach on the wall.

5. Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
8.8 km from Sanctuary
United States
Catherine
$179
$234 total
includes taxes & fees
Oct 19 - Oct 20
Off the Charts Inn & Out Island Resort
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.
A reception area with a beach view mural, a staircase, and a reception desk.
A modern lobby with a fireplace, seating area, and artwork.
A spacious indoor dining area with high ceilings, large windows, and modern orange chairs and white tables.

6. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
19.9 km from Sanctuary
United States
Carol
$74
$83 total
includes taxes & fees
Oct 26 - Oct 27
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
A balcony with a table and chairs, large windows, and a view of the sea.
Spa
An outdoor seating area with round tables and pink cushions, palm trees, and string lights against a twilight sky.
A spacious living area with a high ceiling, a ceiling fan, a pool table, and a view of the outdoors.

7. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
18.1 km from Sanctuary
United States
jessica
$146
$208 total
includes taxes & fees
Oct 25 - Oct 26
The Westin Cape Coral Resort At Marina Village
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.
A hotel room with two beds, a large mirror, and a view of the outdoors.
A hotel lobby with a reception desk, seating area, and a large window.
A modern hotel room with a large bed, two armchairs, a small side table with a lamp, and a large window with blinds.

8. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
19.3 km from Sanctuary
United States
nydeshwia
$86
$96 total
includes taxes & fees
Oct 15 - Oct 16
Residence Inn by Marriott Fort Myers Sanibel
A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.
A table set for two on a beach with a view of the sea and distant islands.
A spacious lobby with a staircase, large windows, and a chandelier.
A spacious living area with wicker furniture, a chandelier, and large windows offering a view of palm trees and a balcony.

9. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
15.6 km from Sanctuary
United States
Matthew
$223
$284 total
includes taxes & fees
Oct 27 - Oct 28
Marriott Sanibel Harbour Resort & Spa
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.
A grocery store with shelves stocked with snacks, beverages, and dairy products.
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and artwork on the walls.
A swimming pool with lounge chairs and palm trees, surrounded by a building with a red roof and multiple windows.

10. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
22.9 km from Sanctuary
United States
Felicia
$86
$96 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
Living area
Room
A boat-shaped deck chair with cushions, positioned on a wooden deck with a white fence.
Dining

11. The Anchor Inn

The Anchor Inn
Mid Island, 12.8 km from Sanctuary
United States
leslie
$142
$174 total
includes taxes & fees
Oct 19 - Oct 20
The Anchor Inn
A pathway flanked by palm trees and wooden buildings with thatched roofs.
A hotel room with a bed, a television, a desk, a chair, and a ceiling fan.
A thatched-roof structure with outdoor seating, surrounded by palm trees and a wooden deck.
A clear blue pool with lounge chairs and umbrellas, surrounded by palm trees and a thatched-roof structure.

12. Kona Kai Motel

Kona Kai Motel
Mid Island, 12.2 km from Sanctuary
United States
Paloma
$179
$206 total
includes taxes & fees
Oct 15 - Oct 16
Kona Kai Motel
A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.
A well-maintained garden with a wooden deck, palm trees, and a building in the background.
A large, two-story house with a wrap-around porch and a steeply pitched roof.
A resort pool area with a clear view of the ocean, surrounded by palm trees and lounge chairs.

13. Casa Ybel Resort

Casa Ybel Resort
Ybel, 11.6 km from Sanctuary
United States
Juan
$238
$265 total
includes taxes & fees
Oct 15 - Oct 16
Casa Ybel Resort
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.
A modern hotel room with a wooden desk, a flat-screen TV, a chair, a wardrobe, and a framed picture on the wall.
A Holiday Inn Express building with a clear entrance, palm trees, and a purple sky.
A breakfast station with a bakery section and a display for breakfast items.

14. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
23.9 km from Sanctuary
United States
Shannon
$103
$115 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Room
A grassy yard with palm trees and a wooden fence.
A covered patio with tiled flooring, wooden lounge chairs, and a small table.
A modern living room with a grey sofa, a small table, and a TV mounted on the wall.

15. White Orchid Apartments

White Orchid Apartments
20 km from Sanctuary
United States
Laura
$65
$105 total
includes taxes & fees
Oct 15 - Oct 16
White Orchid Apartments
An outdoor patio with wicker furniture, a fire feature, and string lights.
A hotel with a clear entrance, a covered waiting area, and a sign indicating a clearance height of 10'-3".
A pool area with a hot tub, lounge chairs, and palm trees.
A modern kitchen with a central island, bar stools, and hanging pendant lights.

16. Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
29.5 km from Sanctuary
United States
Wesley
$100
$112 total
includes taxes & fees
Oct 16 - Oct 17
Hilton Garden Inn Ft Myers
An outdoor seating area with tables and chairs, surrounded by palm trees and a thatched-roof structure.
A nighttime view of a bar with a pool in front.
A lobby with a mural of dolphins, seating area, and a reception desk.
A bar with multiple liquor bottles and a large American flag in the background.

17. Dolphin Key Resort

Dolphin Key Resort
23.8 km from Sanctuary
United States
Patrick
$95
$106 total
includes taxes & fees
Nov 9 - Nov 10
Dolphin Key Resort
A beachside area with colorful Adirondack chairs, a fire pit, and a view of the water.
A balcony with wicker furniture, a pool, and a white fence.
A modern kitchen with white cabinets, granite countertops, a built-in oven, and a microwave.
A bedroom with a large bed, a TV mounted on the wall, two bedside tables with lamps, and a window with blinds.

18. Matlacha on Shoreview

Matlacha on Shoreview
20.2 km from Sanctuary
United States
Jacquelyn
$65
$139 total
includes taxes & fees
Oct 15 - Oct 16
Matlacha on Shoreview
Room
Outdoor pool
Check-in/check-out kiosk
A modern kitchen with white cabinetry, a built-in microwave, a stove, and wooden shelves above holding glassware and a plant.

19. Fountain Cottages Inn

Fountain Cottages Inn
24.2 km from Sanctuary
United States
Lisa
$29
$138 total
includes taxes & fees
Oct 21 - Oct 22
Fountain Cottages Inn
A modern hotel lobby with a seating area, a reception desk, and a dining area.
A reception desk with a "Welcome to the Sun Shine State" sign, a wooden wall, and a minibar.
A Hampton Inn & Suites hotel entrance with a 'Welcome' sign, palm trees, and a well-lit facade.
A modern hotel room with a flat-screen TV mounted on a wooden console, a microwave, a small sink, and a yellow chair.

20. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
22.6 km from Sanctuary
United States
Amy
$93
$103 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
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Our prices for hotels in Sanibel are cheapest in October
Price trends for hotels in Sanibel
Pricing is based on two traveler single night rates
View properties in October
Typical weather for Sanibel
October
High 29°C / low 23°C. Sunny most days.
View properties in October
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Monthly weather averages (˚C)

Check out reviews of Sanctuary hotels guests love

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

8/10 Good
"This resort is a little rough looking on the outside. Also was hit by hurricane ira, so they have done fantastic since then. Perfect for an elderly couple as far as easy access, just the most pleasant and helpful staff and bars and restaurants on site is perfect for us without a car. I would come back here just to be able to talk with the front desk staff!"
Margaret 1-night trip
Posted 2 hours ago
Lani Kai Beachfront Resort
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

10/10 Excellent
"Good breakfast clean rooms good staff help"
Robert 1-night trip
Posted 3 hours ago
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

10/10 Excellent
"This is a great place! We’ve stayed here several times! New pool is fabulous!"
Kimberly 1-night trip
Posted 3 hours ago
The Lighthouse Resort Inn & Suites
Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

10/10 Excellent
"No"
Richard H 1-night trip
Posted 4 hours ago
Pink Shell Beach Resort and Marina
Sanibel Island Beach Resort

Sanibel Island Beach Resort

10/10 Excellent
"I absolutely love this hotel! We celebrated our first anniversary here, and everything was wonderful. The beach staff were especially helpful, kind, and attentive, which made our experience even more special. We truly enjoyed our stay and would definitely love to come back!"
MARIA 1-night trip
Posted 6 hours ago
Sanibel Island Beach Resort
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

10/10 Excellent
"Stay was prefect. Has everything you need."
Eric 5-night trip
Posted 20 hours ago
Margaritaville Beach Resort Fort Myers
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

10/10 Excellent
"I absolutely loved it here at this hotel. I came here due to the pool and it did not disappoint. It’s a 22 m pool so I was able to do lapses. People complain. It was too cold, but I found the water actually warm. The only sad part is that I did not stay the entire week as it was hurricane season and I was not able to do anything due to the rain. Next time I will make sure to book when it’s not gray and rainy. Aside from that the rooms were a little muggy and humid due to the temperature outside but nothing the hotel can do anything about. It is definitely not a luxury hotel but it really worked well for me. The wonderful young man at the front desk with the red hair and blue eyes was so kind. They were able to give me a refund for the remaining days with no questions asked. The breakfast was stunning and delicious, the coffee in the lobby was wonderful. The breakfast room unlike many other hotel was large and spacious so you didn’t have to struggle to find a spot. I really wanna come back at this hotel but like I said, at better times with better weather I highly recommend this hotel as it is incredible deal for your budget. Keep in mind that the cab ride from airport to this hotel is about $50 as it’s not in the centre of town. There is a bus that runs nearby, but not that simple to get and stops running at certain times. Thank you to all the wonderful stuff at this hotel, even though my stay was short it was sweet"
Kathy 7-night trip
Posted 21 hours ago
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

10/10 Excellent
"I love everything about this hotel"
Yunior 1-night trip
Posted 1 day ago
Marriott Sanibel Harbour Resort & Spa
Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG

10/10 Excellent
"Excellent"
arlene 2-night trip
Posted 1 day ago
Candlewood Suites Fort Myers Sanibel Gateway by IHG
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