Hotels in Sanctuary

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Check prices for these dates

Tonight
Oct 21 - Oct 22
Tomorrow
Oct 22 - Oct 23
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Where to stay in Sanctuary?

A resort with multiple swimming pools, sun loungers, and palm trees.
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a clear sky.
A bedroom with two beds, a ceiling fan, and a view of greenery outside.
A spacious dining area with a wooden floor, a large round clock, and a chandelier.

1. South Seas

South Seas
5.5 km from Sanctuary
United States
Jarrett
$202
$341 total
includes taxes & fees
Nov 11 - Nov 12
South Seas
A resort with a central pool, multiple lounge areas, and a beach view.
A sandy pathway leading to a beach with palm trees and a clear sky.
A table set for dining with a view of the sunset over the ocean.
A covered porch with a view of the sea, a white railing, and two Adirondack chairs.

2. Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.7 km from Sanctuary
United States
Nicholas J
$287
$355 total
includes taxes & fees
Oct 22 - Oct 23
Tween Waters Island Resort & Spa
A beach with a variety of seashells and pebbles.
A hammock between palm trees with a view of the ocean.
A landscaped area with palm trees and a view of the ocean.
A hotel room with a bed, a view of the beach, and a window with curtains.

3. Sanibel Island Beach Resort

Sanibel Island Beach Resort
Mid Island, 13.1 km from Sanctuary
United States
Cary
$179
$227 total
includes taxes & fees
Oct 22 - Oct 23
Sanibel Island Beach Resort
A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.
A beachfront hotel with palm trees, a sandy walkway, and a pool.
A resort with a pool, thatched umbrellas, and palm trees.
A bedroom with a large bed, a desk, and a chair. There is a sliding barn door and a painting of a beach on the wall.

4. Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
8.8 km from Sanctuary
United States
Catherine
$179
$234 total
includes taxes & fees
Oct 22 - Oct 23
Off the Charts Inn & Out Island Resort
A beach with a view of the ocean and a sunset.
A multi-story hotel with a central entrance, balconies, and palm trees.
A modern living room with a sofa, chairs, and a dining table. There is a kitchen area with cabinets and appliances.
A covered outdoor area with a table and chairs, a ceiling fan, and a view of a beach with palm trees and a boat.

5. Island Inn

Island Inn
West End, 9.6 km from Sanctuary
United States
Andrew
$280
$312 total
includes taxes & fees
Oct 31 - Nov 1
Island Inn
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.
A spacious indoor dining area with high ceilings, large windows, and modern orange chairs and white tables.
A modern lobby with a white brick wall, a flat-screen TV, and colorful abstract paintings. There are several seating areas with different styles of chairs.
A reception area with a beach view mural, a staircase, and a reception desk.

6. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
19.9 km from Sanctuary
United States
Carol
$74
$83 total
includes taxes & fees
Oct 28 - Oct 29
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
A balcony with a table and chairs, large windows, and a view of the sea.
An outdoor seating area with round tables and pink cushions, palm trees, and string lights against a twilight sky.
A swimming pool with clear blue water, surrounded by lounge chairs and umbrellas, and a building with a tiled roof.
A spacious living area with a high ceiling, a ceiling fan, a pool table, and a view of the outdoors.

7. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
18.1 km from Sanctuary
United States
jessica
$146
$208 total
includes taxes & fees
Nov 15 - Nov 16
The Westin Cape Coral Resort At Marina Village
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.
A hotel lobby with a reception desk, seating area, and a large window.
A hotel room with two beds, a large mirror, and a view of the outdoors.
A swimming pool area with lounge chairs, a small building, and a basketball court surrounded by palm trees and greenery.

8. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
19.3 km from Sanctuary
United States
Benjamin
$94
$105 total
includes taxes & fees
Oct 25 - Oct 26
Residence Inn by Marriott Fort Myers Sanibel
A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.
A spacious living area with wicker furniture, a chandelier, and large windows offering a view of palm trees and a balcony.
A table set for two on a beach with a view of the sea and distant islands.
A resort pool area with a large pool, lounge chairs, and umbrellas.

9. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
15.6 km from Sanctuary
United States
Matthew
$207
$266 total
includes taxes & fees
Nov 3 - Nov 4
Marriott Sanibel Harbour Resort & Spa
Living area
A kitchen with white cabinets, a microwave, a sink, and a green refrigerator.
Room
A boat-shaped deck chair with cushions, positioned on a wooden deck with a white fence.

10. The Anchor Inn

The Anchor Inn
Mid Island, 12.8 km from Sanctuary
United States
Ricardo E
$148
$180 total
includes taxes & fees
Oct 22 - Oct 23
The Anchor Inn
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.
A swimming pool with lounge chairs and palm trees, surrounded by a building with a red roof and multiple windows.
A reception desk with a wooden panel design, a welcome sign for 'Sunshine State', and a motivational rug on the floor.
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and artwork on the walls.

11. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
22.9 km from Sanctuary
United States
Felicia
$78
$87 total
includes taxes & fees
Oct 29 - Oct 30
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
A modern living room with a TV, dining table, and chairs. There is a balcony with a view of palm trees.
A well-maintained garden with a wooden deck, palm trees, and a building in the background.
A resort pool area with a clear view of the ocean, surrounded by palm trees and lounge chairs.
A wooden pathway leading to a beach with a clear view of the ocean.

12. Casa Ybel Resort

Casa Ybel Resort
Ybel, 11.6 km from Sanctuary
United States
Juan
$238
$265 total
includes taxes & fees
Oct 25 - Oct 26
Casa Ybel Resort
A pathway flanked by palm trees and wooden buildings with thatched roofs.
A hotel room with a bed, a television, a desk, a chair, and a ceiling fan.
A thatched-roof structure with outdoor seating, surrounded by palm trees and a wooden deck.
A compact kitchen with a stainless steel refrigerator, a microwave, a coffee maker, and a sink.

13. Kona Kai Motel

Kona Kai Motel
Mid Island, 12.2 km from Sanctuary
United States
Paloma
$179
$206 total
includes taxes & fees
Oct 22 - Oct 23
Kona Kai Motel
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.
A modern reception desk with a digital display, a cash register, and a customer service counter.
A Holiday Inn Express & Suites building with a parking lot, a covered entrance, and a landscaped area with flowers.
A modern indoor space with a large table, chairs, and a television.

14. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
23.1 km from Sanctuary
United States
Phillip
$101
$113 total
includes taxes & fees
Oct 25 - Oct 26
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
A wooden boardwalk leading to a beach with clear skies and calm waters.
A resort with multiple buildings featuring blue roofs, a beach, and a clear view of the ocean.
A pool area with lounge chairs and umbrellas, a wooden deck, and a view of the beach and ocean.
A hotel room with a large bed, a desk, a chair, and a view of the beach through the window.

15. Shalimar Beach Resort

Shalimar Beach Resort
West End, 10.3 km from Sanctuary
United States
Martha
$349
$389 total
includes taxes & fees
Oct 25 - Oct 26
Shalimar Beach Resort
A covered patio with tiled flooring, wooden lounge chairs, and a small table.
Living area
A grassy yard with palm trees and a wooden fence.
A hotel room with a bed, a desk, a chair, a TV mounted on the wall, and a sliding glass door leading to a balcony.

16. White Orchid Apartments

White Orchid Apartments
20 km from Sanctuary
United States
Laura
$65
$105 total
includes taxes & fees
Oct 22 - Oct 23
White Orchid Apartments
A spacious living room with a grey sofa, striped armchair, and a woven coffee table. Large windows offer a view of a tropical garden.
A garden with a thatched-roof structure, palm trees, and a gravel path.
A bedroom with a bed, nightstands, a ceiling fan, a window with a view of greenery, and a sliding glass door.
An aerial view of a coastal residential area with a beachfront, including a large hotel complex with multiple buildings and a parking lot.

17. Driftwood Inn

Driftwood Inn
Mid Island, 13.1 km from Sanctuary
United States
Heather
$216
$482 total
includes taxes & fees
Oct 25 - Oct 26
Driftwood Inn
An outdoor seating area with tables and chairs, surrounded by palm trees and a thatched-roof structure.
A bar with multiple liquor bottles and a large American flag in the background.
A nighttime view of a bar with a pool in front.
A lobby with a mural of dolphins, seating area, and a reception desk.

18. Dolphin Key Resort

Dolphin Key Resort
23.8 km from Sanctuary
United States
Patrick
$95
$106 total
includes taxes & fees
Nov 9 - Nov 10
Dolphin Key Resort
A beachside area with colorful Adirondack chairs, a fire pit, and a view of the water.
A bedroom with a large bed, a TV mounted on the wall, two bedside tables with lamps, and a window with blinds.
A modern kitchen with white cabinets, granite countertops, a built-in oven, and a microwave.
A balcony with wicker furniture, a pool, and a white fence.

19. Matlacha on Shoreview

Matlacha on Shoreview
20.2 km from Sanctuary
United States
Jacquelyn
$60
$134 total
includes taxes & fees
Oct 22 - Oct 23
Matlacha on Shoreview
A hotel with a modern facade, palm trees, and a clear blue sky.
A hotel room with a sofa, armchair, TV, and a small table with a vase.
A compact kitchen with a wooden table, chairs, a refrigerator, a microwave, and cabinets.
A hotel room with a large bed, two bedside tables with lamps, a nightstand, and a window with curtains.

20. Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
25.4 km from Sanctuary
United States
Beatrice
$67
$75 total
includes taxes & fees
Oct 25 - Oct 26
Candlewood Suites Fort Myers Sanibel Gateway by IHG
View all properties

Compare popular hotels in Sanctuary

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A resort with a central pool, multiple lounge areas, and a beach view.
Tween Waters Island Resort & Spa
8.6
Excellent
1,000 reviews
View
A wooden boardwalk leading to a beach with clear skies and calm waters.
Shalimar Beach Resort
9.8
Exceptional
108 reviews
View
A resort with multiple swimming pools, sun loungers, and palm trees.
South Seas
8.4
Very good
1,003 reviews
View
A beach with a variety of seashells and pebbles.
Sanibel Island Beach Resort
9.2
Wonderful
2,372 reviews
View
A beach with a view of the ocean and a sunset.
Island Inn
9.4
Exceptional
1,164 reviews
View
Our prices for hotels in Sanibel are cheapest in October
Price trends for hotels in Sanibel
Pricing is based on two traveler single night rates
View properties in October
Typical weather for Sanibel
October
High 29°C / low 23°C. Sunny most days.
View properties in October
29°
23°
25°
20°
23°
18°
21°
15°
23°
17°
24°
18°
27°
21°
29°
23°
30°
26°
31°
27°
31°
27°
30°
26°
Monthly weather averages (˚C)

Check out reviews of Sanctuary hotels guests love

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

8/10 Good
"A nice “retro” hotel with easy access to the beach. The Tiki Bar was straight out of the early sixties - the only tell was the modern music they played. The beach was great, but we were there immediately after a hurricane passed through, so the water was turbid and there was loads of seaweed along the high-water mark. It reminded me of a natural and unassuming shoreline from Florida’s past."
Tim 1-night trip
Posted 7 hours ago
The Lighthouse Resort Inn & Suites
Sanibel Island Beach Resort

Sanibel Island Beach Resort

10/10 Excellent
"We enjoyed our time here so much! It was a great location to all the beaches, restaurants and shopping. It was very updated & cute!"
Lori 5-night trip
Posted 13 hours ago
Sanibel Island Beach Resort
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

10/10 Excellent
"Great view of the Gulf, nice beach, chair/umbrella rental and a great Italian Restaurant. The only thing I could’ve done without was one of their beach bars starts playing at 9:30am and could’ve lowered the volume till 11:00am."
Karl 1-night trip
Posted 15 hours ago
Lani Kai Beachfront Resort
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

10/10 Excellent
"Everything was awesome with our stay. The only thing I would recommend is new pool furniture that's comfortable. It was like sitting on metal bars. Other than that we would definitely stay again!!"
Jean 3-night trip
Posted 17 hours ago
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

10/10 Excellent
"I stay often in Fort Myers (family), this is 1st at Garden Inn, I will definitely stay here in the future. Everything was immaculate, staff is friendly and ever so helpful. The rates were less than what I had been paying for someplace a few mins closer to the family. Discovered Garden Inn was <5 mins further, worth the extra few mins at less the cost. We ordered a breakfast to take to our room, cooked to order and plentiful."
Jo 1-night trip
Posted 2 days ago
Hilton Garden Inn Ft Myers
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

10/10 Excellent
"Very clean and nice place!"
Charles 2-night trip
Posted 2 days ago
The Westin Cape Coral Resort At Marina Village
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

8/10 Good
"Gotta get rid of the sand chiggers."
Jelani 1-night trip
Posted 4 days ago
Sundial Beach Resort & Spa
Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG

10/10 Excellent
"Excellent"
arlene 2-night trip
Posted 8 days ago
Candlewood Suites Fort Myers Sanibel Gateway by IHG
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