Business Hotels in Colon

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Business Hotels in Colon

A spacious lobby with a reception desk, seating area, and a second-floor balcony.

A modern hotel with a pool, featuring a large glass facade and a rooftop terrace.

A modern lobby with a long reception desk, black sofas, and green vertical gardens.

A modern hotel with a prominent 'SAND DIAMOND' sign, featuring a glass facade and a white lower section.

SAND DIAMOND HOTEL

Colon

$105

$116 total

includes taxes & fees

Aug 25 - Aug 26

A hotel entrance with a stone facade, a glass door, and two potted plants.

A large dam with water flowing through its gates, surrounded by green fields and a small body of water.

A bedroom with a bed, a TV mounted on the wall, an air conditioning unit, and a bedside table.

A historical cannon overlooking a body of water with boats and a small island in the distance.

La Cubana Hotel & Residencial

Cristobal

$30

$33 total

includes taxes & fees

Aug 29 - Aug 30

A hotel with a swimming pool, a covered area, and a multi-story building with balconies.

A spacious lobby with high ceilings, a central seating area, and large windows offering views of the outdoors.

A spacious lobby with a glass staircase, large arched windows, and a dragon sculpture.

A spacious atrium with a glass ceiling, a staircase, and lush indoor plants.

Gamboa Rainforest Reserve

Colon

$137

$151 total

includes taxes & fees

Sep 8 - Sep 9

A buffet with various food items including fruits, juices, and cheeses.

A gym with treadmills, weight machines, and dumbbells.

A modern hotel lobby with a sectional sofa, a glass coffee table, and a vibrant green wall mural.

An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.

Courtyard by Marriott Panama Metromall

San Antonio

$98

$108 total

includes taxes & fees

Aug 28 - Aug 29

A hotel entrance with a central water feature, seating areas, and potted plants.

A pool with a central water feature, surrounded by seating areas and potted plants.

A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.

An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Juan Diaz

$269

$296 total

includes taxes & fees

Sep 3 - Sep 4

A buffet with various food items and a decorative plant.

A hotel with a swimming pool, outdoor seating, and a modern architectural design.

A gym with treadmills, weight machines, and a red carpet.

A spacious lobby with a high ceiling, a glass railing on the upper level, and a seating area with modern furniture.

Sheraton Grand Panama

San Francisco

$176

$193 total

includes taxes & fees

Aug 31 - Sep 1

A poolside area with lounge chairs and a view of the ocean.

A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.

A terrace with seating and a view of the ocean.

A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.

JW Marriott Panama

San Francisco

$271

$298 total

includes taxes & fees

Sep 11 - Sep 12

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

A modern hotel room with a dining area, a TV, and a city view.

A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.

A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

Hotel Riu Plaza Panama

Bella Vista

$138

$151 total

includes taxes & fees

Sep 15 - Sep 16

A modern outdoor swimming pool with a clear view of a tall building in the background.

A modern reception area with a brick wall, wooden paneling, and a neon sign.

A modern urban pathway lined with lush greenery and a pool, leading to a building with balconies and a clear sky.

A modern kitchen with a curved island, bar stools, pendant lighting, and wooden shelving with plants.

Dovle Residences by HMS-Preferred Member

San Francisco

$138

$152 total

includes taxes & fees

Aug 26 - Aug 27

A hotel with a pool, beach, and palm trees.

A beachfront hotel with a large building, a beach, and a clear sky.

A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.

A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.

The Westin Playa Bonita Panama

Veracruz

$206

$227 total

includes taxes & fees

Sep 19 - Sep 20

A resort with a pool area, lounge chairs, and a view of a bridge at night.

A balcony with two wooden chairs, a white balustrade, and a view of boats and palm trees on a calm sea.

A modern living room with a sofa, chairs, a coffee table, and a staircase leading to a balcony.

A spacious hotel lobby with a central bar area, seating arrangements, and large windows allowing natural light.

Radisson Hotel Panama Canal

Amador

$94

$104 total

includes taxes & fees

Aug 25 - Aug 26

A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

A spacious hotel lobby with modern furniture, large windows, and a city view.

A spacious lobby with a curved ceiling, a central staircase, and a reception desk.

A modern building with a sign reading 'HYATT REGENCY.'

Hyatt Regency Panama City

Bella Vista

$224

$246 total

includes taxes & fees

Sep 15 - Sep 16

A modern, well-lit buffet area with a variety of food items and neatly arranged plates.

A hotel room with a bed, bedside lamps, a TV, a bedside table, a mirror, and a desk with a computer.

A modern living room with a sofa, armchairs, a coffee table, and a dining area with a table and chairs.

A spacious indoor area with a high ceiling, potted plants, and a seating arrangement.

Best Western El Dorado Panama Hotel

Bethania

$100

$110 total

includes taxes & fees

Aug 25 - Aug 26

A balcony with a table, chairs, and a view of a city skyline across a body of water.

A spacious lobby with a round coffee table, seating areas, and a large wall clock.

A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.

A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

Sofitel Legend Casco Viejo, Panama City

Casco Viejo

$342

$376 total

includes taxes & fees

Sep 8 - Sep 9

A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.

A buffet setup with various dishes and utensils.

A spacious lobby with high ceilings, large windows, and modern lighting fixtures.

A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.

Marriott Panama Hotel

Panama City

$161

$177 total

includes taxes & fees

Aug 30 - Aug 31

A multi-story building with balconies, arched windows, and decorative railings.

A building with a balcony and a street view.

A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.

A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.

Central Hotel Panama Casco Viejo

Casco Viejo

$183

$202 total

includes taxes & fees

Sep 22 - Sep 23

A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.

An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.

A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.

A modern lobby with a staircase, marble flooring, and large windows with tropical plants.

Renaissance Panama City Hotel

Bella Vista

$127

$140 total

includes taxes & fees

Aug 30 - Aug 31

A multi-story building with ornate balconies, large windows, and decorative moldings.

A luxurious room with ornate chandeliers, a large mirror, and a bar area with shelves of bottles.

A spacious restaurant with high wooden ceilings, multiple tables and chairs, and a bar area with shelves of bottles and glasses.

A spacious hotel room with a large bed, a seating area with a sofa and chairs, a dining table, and a staircase.

Hotel Plaza Herrera

Casco Viejo

$245

$270 total

includes taxes & fees

Aug 25 - Aug 26

A balcony with wicker chairs and a view of the cityscape.

A rooftop pool area with a view of high-rise buildings in the background.

A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.

A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.

Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco

$109

$120 total

includes taxes & fees

Aug 28 - Aug 29

A restaurant with multiple dining tables, chairs, and a central water feature.

A bar area with multiple seating options, a bar counter, and a fireplace.

A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.

Hotel La Compañía Casco Antiguo

Casco Viejo

$318

$350 total

includes taxes & fees

Sep 17 - Sep 18

See more properties

Top neighborhoods in Colon

An aerial view of a coastal area with a large body of water, a bridge, and a solar power plant.

Barrio Sur

Barrio Sur serves up Panama's vibrant Afro-Caribbean heritage with a side of history you can practically taste. Colonial buildings in faded pastels line narrow streets where reggae beats and the smell of fried plantains fill the air. The nearby Colón Art and Culture Center showcases local traditions while Limon Bay offers waterfront views just steps away. You'll feel like a local exploring this historic district with its rich maritime past. Family-run eateries dish up authentic rice and beans and fresh seafood at wallet-friendly prices. The compact neighborhood is perfect for walking, though taxis are available when needed. Basic guesthouses and hostels provide authentic stays without the frills, creating a genuine cultural experience far from typical tourist paths.

See properties

A canal with a lock system, a large cargo ship, and a white building with "PANAMA CANAL" written on it.

A white building with a red roof, labeled "Gatun Locks Panama Canal 1913."

A bridge over a river with a dock and a crowd of people.

A lock canal with ships, a bridge, and a forested island in the distance.

A large ship named 'FREJA BREEZE' entering a harbor.

Cristobal

Cristobal serves up front-row views of massive ships navigating the Panama Canal's Caribbean entrance. This historic port neighborhood blends weathered colonial architecture with the rhythmic pulse of maritime commerce. The Gatun Locks showcase engineering marvels while the waterfront promenade offers breezy spots to watch ocean-going giants pass by. Local eateries dish out Caribbean-influenced Panamanian seafood and traditional sancocho. Nearby Colon Free Zone tempts with duty-free shopping for everything from electronics to designer goods. Most visitors get around by taxi, though walking works fine within central areas if you're looking to soak up the authentic port atmosphere.

See properties

A statue of a historical figure pointing upwards with a bird in hand, set against a backdrop of a clear blue sky with scattered clouds.

Barrio Norte

Barrio Norte offers an authentic glimpse into everyday Panamanian life, away from the tourist crowds. Caribbean flavors fill family-run comedores where you can enjoy rice and beans with fresh seafood. Stroll past colorful concrete homes with neighbors chatting on porches while Caribbean music drifts through open windows. Visit nearby Limon Bay or the Monument to Christopher Columbus for sightseeing. Getting around means navigating uneven sidewalks or catching local buses with irregular schedules. Basic guesthouses offer genuine cultural exchange with friendly locals. Although lacking formal attractions, the neighborhood's Afro-Caribbean and West Indian influences create an immersive experience at a fraction of the cost of Panama City.

See properties

Top landmarks in Colon

Fort San Lorenzo

8.4/10 (36 reviews)

Fort San Lorenzo is just one of the landmarks located 7.5 mi (12 km) from central Colon, so you might want to stop by for a few pics during your trip.

See properties

Colon 2000

7.6/10 (88 reviews)

If you want to give your credit card some exercise, head out to Colon 2000 in Barrio Sur. Splash some more cash at Colon Free Zone.

See properties

Colon Free Zone

7.8/10 (127 reviews)

If you want to give your credit card some exercise, head out to Colon Free Zone in Barrio Sur. Splash some more cash at Colon 2000.

See properties

Gamboa Rainforest Resort

8.4/10 (571 reviews)

Gamboa Rainforest Resort is 0.4 mi (0.7 km) from central Gamboa, why not stop by during your stay. Want to stretch your legs some more? Head to Summit Botanical Gardens & Zoo, located nearby.

See properties

Canal Expansion Observation Center

9.2/10 (34 reviews)

If visiting museums in Colon are on your list, you might want to check out the upcoming exhibitions at Canal Expansion Observation Center. If you want to experience more of the culture Colon has to offer, head to Gatun Locks.

See properties

Galeta Island Marine Education Center

8.2/10 (21 reviews)

If visiting museums in Colon are on your list, you might want to check out the upcoming exhibitions at Galeta Island Marine Education Center. If you want to experience more of the culture Colon has to offer, head to Colon 2000, Colon Free Zone, and Monument to Christopher Columbus.

See properties

Monument to Christopher Columbus

8.2/10 (21 reviews)

If you're planning a bit of sightseeing head to Monument to Christopher Columbus— just one of the monuments in Barrio Norte.

See properties

Fantastic Casino | Colón 2000

You might want to try your luck with an evening at Fantastic Casino | Colón 2000 in Barrio Sur.

See properties